[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidad de Zaragoza\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":403},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,48,76,105,127,170,190,207,232,266,293,325,354,376],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100053218","effect-of-dry-needling-plus-vibration-on-myofascial-trigger-points-in-individuals-with-nonspecific-low-back-pain-100053218",false,"NCT06527339","Effect of Dry Needling Plus Vibration on Myofascial Trigger Points in Individuals With Nonspecific Low Back Pain","Acceptability and Effectiveness of Adding a Percutaneous Vibratory Stimulus to Dry Needling for the Treatment of Myofascial Trigger Points in Nonspecific Low Back Pain: A Randomized Controlled Trial.","Inclusion Criteria:\n\n1. Individuals with NSLBP: pain persisting for more than six weeks, located between the twelfth rib and the buttocks, and scoring at least 3 points on the Numeric Pain Rating Scale;\n2. Presence of MTrPs in any of the following muscles that are associated with low back pain (erector spinae muscles, longissimus, iliocostalis, multifidus, gluteus maximus, gluteus medius, and quadratus lumborum);\n3. Aged between 35-65 years: this population exhibits the highest prevalence of low back pain and consequently represents the greatest socio-economic impact on society;\n4. Having signed the informed consent form.\n\nExclusion Criteria:\n\n1. Diagnosis of specific pathologies associated with low back pain (e.g., herniated discs, neurological disorders);\n2. Any form of infiltration within the past 3 months;\n3. Having received any physiotherapy interventions in the lumbopelvic region within the past 4 weeks;\n4. History of surgical intervention in the lumbopelvic region;\n5. Use of anticoagulant or antiplatelet medications within the last week;\n6. Presence of systemic or local lumbar infections;\n7. Pregnancy;\n8. Fear of needles (belonephobia).","ALL","35 Years","65 Years",{"count":20,"type":21},36,"ESTIMATED","INTERVENTIONAL",[24],"NA","Low back pain is one of the most common health issues worldwide, and in most cases, this pain is nonspecific low back pain (NSLBP). NSLBP is characterized by the inability to determine the real source of the pain and commonly presents with myofascial trigger points (MTrPs) in the muscles related to the lumbar region.\n\nOne of the most widely used techniques for treating NSLBP by targeting MTrPs is dry needling (DN), a technique that involves inserting a needle to produce a mechanical effect capable of \"deactivating\" the MTrP and thereby alleviating its symptoms. However, some studies have concluded that other techniques are more effective than DN, such as percutaneous electrolysis (PE).\n\nWhen using the PE technique, it appears that adding a galvanic current enhances the effects of DN. Nonetheless, this poses a greater risk to the patient, as the galvanic current could damage nervous tissue if it comes into contact. For this reason, it is proposed to investigate whether other physical agents that are not electrical could enhance the effect of DN without increasing its risk. This is the case for vibration, a stimulus that has already been used successfully for the treatment of MTrPs, allowing us to investigate whether adding vibration to DN introduces therapeutic capabilities that:\n\n* Maintain or increase the effectiveness of DN in terms of pain and functional capacity.\n* Do not add risks for the patient, unlike PE.\n* Are less painful than DN and cause less post-needling pain than that generated after successive needle insertions with DN. Emphasizing these adverse effects is necessary since most clinical trials do not report these variables, which is fundamental for describing the safety of invasive techniques.\n\nFollowing this idea, the present project will analyze a new invasive therapy for the treatment of MTrPs: dry needling with vibratory stimulus (DN+V), for which the following hypotheses are proposed:\n\n* DN+V, instead of using an electrical stimulus like PE that could cause damage to some tissues, will apply vibration to the DN needles to increase the mechanical stimulus exerted on the MTrP, expecting greater benefits in terms of pain, functional capacity, muscle strength, and other variables of interest in individuals with NSLBP, and possibly requiring less treatment time than DN.\n* In DN, the repeated insertions and withdrawals of the needle in the MTrP provoke a hemorrhagic and inflammatory reaction that translates into hypersensitivity and microscopic tissue injury in the muscle, causing pain during treatment and post-needling pain for the following 24-32 hours. Another study showed that PE caused less post-needling pain than DN, which may be due to the fact that, unlike DN, it is common in PE to only perform a single puncture with each needle and not mobilize them.\n* The methodology for DN+V will be the same as for PE, with a single puncture and no needle manipulation, so it is expected that DN+V, being less invasive than DN, will reduce pain during treatment and post-needling pain compared to that generated by DN. There are studies that support this hypothesis, concluding that needle manipulation in DN produces greater post-needling pain than DN without needle manipulation.",[27,28,29,30],"Low Back Pain","Dry Needling","Trigger Points","Vibration",[32,33,34],"Non-specific low back pain","vibration dry needling","miofascial trigger points","NOT_YET_RECRUITING","2026-07-08",{"date":38,"type":39},"2026-07-13","ACTUAL",{"date":41,"type":21},"2026-09",{"date":43,"type":21},"2027-07",{"name":45,"class":46},"Universidad de Zaragoza","OTHER",2,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},"100622167","development-of-a-qualitative-scale-to-asses-the-acceptability-of-percutaneous-techniques-a-delphi-study-100622167","NCT07380100","Development of a Qualitative Scale to Asses the Acceptability of Percutaneous Techniques. A Delphi Study","Accept_scale","Experts were required to:\n\n* have at least five years of experience in percutaneous techniques\n* have clinical experience working with patients with pain",true,{"count":57,"type":21},65,"OBSERVATIONAL","This study aims to develop a new evaluation tool to assess patient acceptability of percutaneous interventions. A Delphi methodology will be implemented, involving the recruitment of a panel of experts in percutaneous interventions and pain management. The scale will be developed through several iterative phases until a final version is reached, comprising clearly defined domains, subdomains, items, and questions to be answered by patients in order to obtain an overall acceptability score for the percutaneous technique received. The scale is intended to be applicable across a wide range of percutaneous interventions and, consequently, to a broad patient population undergoing different percutaneous treatments depending on their clinical condition.",[61],"Acceptability of Percutaneous Interventions",[63,64,65],"Acceptability","Scale","Percutaneous Interventions","RECRUITING","2026-06-09",{"date":69,"type":39},"2026-06-11",{"date":71,"type":39},"2025-04-01",{"date":73,"type":21},"2026-08-01",{"name":45,"class":46},1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":55,"sex":16,"minAge":84,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":75},"100639259","rideclas-delphi-classification-of-rica-pathway-recommendations-100639259","NCT07615855","RIDECLAS: Delphi Classification of RICA Pathway Recommendations","Delphi Study for the Classification of Recommendations for the RICA Pathway (Enhanced Recovery in Adult Surgery)","RIDECLAS","Inclusion Criteria:\n\n* Healthcare professional or researcher with relevant clinical or scientific experience in enhanced recovery pathways, perioperative medicine, surgery, anesthesiology, nursing, rehabilitation, or related disciplines.\n\nAt least 5 years of professional experience. Membership in GERM or participation in professional networks related to enhanced recovery in adult surgery.\n\nWillingness to participate in the planned Delphi rounds. Provision of electronic informed consent.\n\nExclusion Criteria:\n\n* Failure to meet the predefined professional experience criteria. Failure to provide informed consent. Failure to complete the first Delphi round. Duplicate or incomplete responses that cannot be validated for analysis.","18 Years",{"count":86,"type":21},384,"RIDECLAS is an observational, prospective, non-interventional consensus study using a modified Delphi methodology. The study aims to obtain expert consensus on the classification and final formulation of recommendations for the RICA Pathway, an enhanced recovery pathway for adult surgery. Participants will be healthcare professionals with experience in enhanced recovery, perioperative medicine, surgery, anesthesiology, nursing, rehabilitation, or related disciplines. Experts will complete sequential online questionnaires. Individual responses will remain confidential, and aggregated anonymized feedback will be provided between Delphi rounds. The study does not involve patients, clinical interventions, biological samples, drugs, or medical devices.",[89,90,91],"Enhanced Recovery After Surgery","Perioperative Care","Surgical Care",[93,94,95,96],"ERAS","Delphi Technique","RICA Pathway","Perioperative Medicine","2026-05-22",{"date":99,"type":39},"2026-05-29",{"date":101,"type":21},"2026-06-01",{"date":103,"type":21},"2026-12-31",{"name":45,"class":46},{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":16,"minAge":84,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":22,"phases":115,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":75},"100631172","change-in-ator-screening-test-scores-over-12-weeks-100631172","NCT07497217","Change in ATOR Screening Test Scores Over 12 Weeks","Validity of a Screening Test Compared to Other Measures in Senior Runners With Achilles Tendinopathy After a Physiotherapy Protocol","ATOR","Inclusion Criteria:\n\n* Senior runners\n* They belong to a running club\n* That they have run at least 5 10-kilometer races in the past year\n* They should work out at least three times a week\n\nExclusion Criteria:\n\n* Runners who have received physiotherapy treatment involving invasive techniques in the last 3 months\n* Runners who have received pharmacological treatment with fluoroquinolones (levofloxacin, ciprofloxacin) in the last year\n* Runners with autoimmune diseases\n* Individuals with limited comprehension who may be unable to answer surveys",{"count":114,"type":21},40,[24],"Achilles tendinopathy (AT) is one of the most common overuse injuries in runners, with an estimated incidence ranging from 0.6% to 18.5% of all running-related injuries, reaching up to 52% in elite runners. Its prevalence increases significantly from the fourth decade of life due to histological changes associated with aging, such as tissue degeneration, decreased vascularization, alterations in collagen structure, reduced recovery capacity, and increased tendon stiffness. The repetitive nature of running and the high proportion of the population practicing this sport make runners, especially those over 40 years old, a particularly vulnerable group.\n\nThe etiology of AT is multifactorial and includes biomechanical, physiological, and contextual factors. Major risk factors include sudden increases in load, planning errors in training, biomechanical alterations, overweight, metabolic comorbidities such as diabetes or dyslipidemia, and exposure to certain medications, especially corticosteroids and fluoroquinolones. In middle-aged individuals, the combination of intrinsic and extrinsic factors along with structural tendon changes explains both the higher prevalence and the worse prognosis observed in this population.\n\nPhysiotherapy is one of the preferred treatments for AT, with therapeutic exercise-particularly the Alfredson protocol-being the intervention with the strongest scientific support. Despite its efficacy, between 25% and 45% of patients do not achieve full recovery, suggesting the influence of clinical, personal, and contextual factors not always considered in studies. Additionally, there is high variability in return-to-sport times, which has led to the development of specific programs for runners over 40.\n\nIn the Aragón community, there are no studies describing the extent of AT in senior runners nor systematically analyzing their clinical characteristics, comorbidities, referral patterns, or healthcare service use. This lack of information hampers evidence-based decision-making and the planning of preventive and therapeutic strategies in physiotherapy. This study aims to fill this gap by providing contextualized information to improve clinical practice, healthcare pathways, and physiotherapeutic guidelines.\n\nThe hypothesis of the study is that an assessment system using screening has validity for detecting clinical changes in senior runners with Achilles tendon pain. The main objective is to determine the validity of this screening compared to other clinical measures after applying a physiotherapy protocol.\n\nA clinimetric validity design is proposed. The sample will include 40 runners over 40 years old, belonging to sports clubs, who train at least three days a week and have participated in at least five 10 km races in the past year. Participants will be recruited through running clubs and social media, and randomly assigned to two groups of 20 people each. Exclusion criteria include recent invasive treatments, use of fluoroquinolones in the last year, autoimmune diseases, or difficulties understanding questionnaires.\n\nData collected will include sociodemographic, anthropometric, sports activity, and clinical variables through validated scales (VISA-A, NPRS, IPAQ, and SMFA), as well as ultrasound characteristics of the tendon, ankle mobility, passive calcaneal mobility, and functional screening tests based on active movements and jumps.\n\nThe procedure involves initial measurements, random assignment to control or experimental groups, and a 12-week home self-treatment program. Both groups will perform the Alfredson exercise protocol and receive health education; the experimental group will add analytical stretching of the posterior chain following OMT methodology.\n\nStatistical analysis will assess intergroup and intragroup differences using repeated measures ANOVA, analyze time-group interactions, and include sensitivity-to-change statistics such as effect size, minimal clinically important difference, and reliable change index.\n\nA gender perspective will be incorporated, limiting the representation of one sex to a maximum of 70% of the sample and analyzing results separately by gender. Main limitations include the small sample size, short follow-up duration, and limited control over adherence to home treatment.\n\nFinally, the study clearly defines internal and external validity and clarifies the use of the term screening as a functional discrimination tool within a homogeneous and clinically defined population, without asserting generalization to the broader population.",[118],"Achilles Tendinopathy (AT)","2026-03-27",{"date":121,"type":39},"2026-04-02",{"date":123,"type":39},"2026-02-16",{"date":125,"type":21},"2026-07-18",{"name":45,"class":46},{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":11,"sex":16,"minAge":84,"maxAge":4,"enrollmentInfo":134,"targetDuration":4,"studyType":22,"phases":136,"briefSummary":137,"conditions":138,"keywords":145,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":47},"100631700","active-coping-interdisciplinary-program-for-chronic-pain-physiotherapy-unit-spain-100631700","NCT07504094","Active Coping: Interdisciplinary Program for Chronic Pain, Physiotherapy Unit (Spain)","Interdisciplinary Active Coping Program for Chronic Pain in the Physiotherapy Unit in Primary Care - Teruel Health Sector (Aragón, Spain)","Inclusion Criteria:\n\n* Adult (18 years or older)\n* Diagnosis of non-oncological chronic back pain\n* Referred from Primary Care to the Physiotherapy Unit of Teruel Ensanche . (UFAP) from one of the following basic health zones: Teruel Centro, Teruel Ensanche, Albarracín, Alfambra, Cella, or Villel\n* Able to provide voluntary written informed consent\n\nExclusion Criteria:\n\n* Oncological pain\n* Cognitive impairment that prevents following the program\n* Spinal surgery in the last year\n* Internal electrostimulator device (e.g. pacemaker, spinal cord stimulator)",{"count":135,"type":21},20,[24],"The goal of this observational intervention study is to evaluate the impact of a multidisciplinary active coping program for chronic back pain in adults referred from Primary Care to the Physiotherapy Unit of Teruel Ensanche. The main questions it aims to answer are:\n\n* Does the program improve physical function, measured through gait speed, balance, and chair stand tests?\n* Does it reduce pain-related psychological factors such as kinesiophobia, catastrophizing, anxiety, and depression?\n* Does it improve quality of life and sleep quality, and reduce analgesic medication use?\n\nParticipants will attend group sessions on pain neuroscience education, followed by sessions on healthy habits, nutrition and sleep hygiene and group psychological intervention focused on emotional wellbeing tools, and will complete therapeutic exercise sessions over the course of the program. They will also complete validated questionnaires and physical assessments at three timepoints: at baseline, at the end of the program, and at a 6-month follow-up.",[139,140,141,142,143,144],"Chronic Back Pain","Chronic Pain","Back Pain","Low Back Pain, Chronic","Musculoskeletal Pain","Kinesiophobia",[146,147,148,149,150,139,151,152,153,154,155,156,157,158,159,160,161],"Pain Neuroscience Education","Therapeutic Exercise","Multidisciplinary Intervention","Active Coping","Psychological Intervention","Chronic Musculoskeletal Pain","Central Sensitization","Pain Catastrophizing","Primary Care","Physiotherapy","Primary Care Physiotherapy Unit","Quality of Life","Physical Function","Sleep Quality","Anxiety","Depression","2026-03-26",{"date":164,"type":39},"2026-03-31",{"date":166,"type":21},"2026-04-01",{"date":168,"type":21},"2028-02",{"name":45,"class":46},{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":55,"sex":16,"minAge":84,"maxAge":17,"enrollmentInfo":177,"targetDuration":4,"studyType":22,"phases":178,"briefSummary":179,"conditions":180,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":187,"leadSponsor":189,"locationsCount":4},"100623376","effects-of-a-multisensory-vr-experience-on-stress-and-user-experience-100623376","NCT07395830","Effects of a Multisensory VR Experience on Stress and User Experience","Effects of a Multisensory VR Experience on Stress and User Experience: A Randomized Controlled Study","Inclusion Criteria:\n\n* must meet the required age.\n* must have corrected vision\u002Fhearing.\n\nExclusion Criteria:\n\n* uncontrolled asthma.\n* uncontrolled odor-triggered migraines.\n* pregnancy state.\n* nasal congestion.\n* severe predisposition to dizziness in virtual reality.",{"count":114,"type":21},[24],"This study explicitly tests a multisensory virtual reality experience that combines visual, auditory, and olfactory channels to modulate the stress response in young adults. In addition to visual and auditory stimulation, the study also assesses whether a relaxing olfactory stimulus attenuates this effect. The environment and task remain constant (constant visuals); auditory and olfactory elements are varied. Objective. To evaluate the main effects of varying auditory and olfactory stimuli, as well as their interaction, on variables related to the performance of a quiz-type task in virtual reality.",[181,182],"To Evaluate the Main Effects of Varying Auditory Stimuli","To Evaluate the Main Effects of Varying Olfactory Stimuli","2026-02-06",{"date":185,"type":39},"2026-02-10",{"date":185,"type":21},{"date":188,"type":21},"2026-05-01",{"name":45,"class":46},{"id":191,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":192,"acronym":4,"eligibilityCriteria":193,"healthyVolunteers":11,"sex":16,"minAge":84,"maxAge":4,"enrollmentInfo":194,"targetDuration":4,"studyType":22,"phases":195,"briefSummary":25,"conditions":196,"keywords":198,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":199,"lastUpdatePostDateStruct":200,"startDateStruct":202,"completionDateStruct":204,"leadSponsor":206,"locationsCount":75},"100556610","RCT: Analysis of the Effectiveness on Pain in Individuals With Nonspecific Low Back Pain by Adding a Percutaneous Vibratory Stimulus to Dry Needling in the Treatment of MTrPs","Inclusion Criteria:\n\n* Individuals with nonspecific low back pain, defined as pain persisting for more than 3 months between the twelfth rib and the buttocks, registering a Numeric Pain Rating Scale (NPRS) score of 3 or higher prior to the intervention. Additionally, participants must meet the following criteria:\n* Presence of myofascial trigger points (PGMs) in any of the following muscles relevant to the project: erector spinae (longissimus and iliocostal), multifidus, gluteus maximus, gluteus medius, and quadratus lumborum. Detection of these PGMs will be conducted by a specialized physiotherapist.\n* Individuals aged 18 years or older, proficient in either Spanish or English. Participants who have provided informed consent by signing the consent form\n\nExclusion Criteria:\n\n* Diagnosis of lumbar pain associated with specific pathologies such as disc herniations or neurological disorders.\n* Recent infiltration therapy within the past 3 months.\n* Recent manual therapy, acupuncture, or dry needling interventions in the lumbopelvic region within the last 4 weeks.\n* Previous surgical intervention in the lumbopelvic region.\n* Leg length discrepancy (\\>1 cm).\n* Recent use of anticoagulant or antiplatelet medications within the last week.\n* Systemic or local infection in the lumbar region.\n* Pregnancy.\n* Needle phobia (belonephobia).",{"count":20,"type":21},[24],[27,28,197,29],"Electrolysis",[32,33,34],"2025-11-27",{"date":201,"type":39},"2025-12-04",{"date":203,"type":21},"2026-05",{"date":205,"type":21},"2026-12",{"name":45,"class":46},{"id":208,"slug":209,"hasResults":11,"nctId":210,"briefTitle":211,"officialTitle":211,"acronym":4,"eligibilityCriteria":212,"healthyVolunteers":11,"sex":16,"minAge":84,"maxAge":4,"enrollmentInfo":213,"targetDuration":4,"studyType":22,"phases":215,"briefSummary":216,"conditions":217,"keywords":219,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":199,"lastUpdatePostDateStruct":226,"startDateStruct":227,"completionDateStruct":229,"leadSponsor":231,"locationsCount":75},"100517470","effects-of-dry-needling-on-electromyographic-activity-and-ultrasonographic-characteristics-in-post-stroke-spasticity-100517470","NCT06017960","Effects of Dry Needling on Electromyographic Activity and Ultrasonographic Characteristics in Post-Stroke Spasticity","Inclusion Criteria:\n\n* be over 18 years old\n* understand and voluntarily sign informed consent before performing the intervention\n* have a medical diagnosis of ischemic or hemorrhagic stroke\n* have a grade between 1-3 according to the modified Ashworth scale (MAS) on the triceps sural\n* able to walk independently to perform gait test\n\nExclusion Criteria:\n\n* recurrent stroke\n* who have received previous treatments of botulinum toxin type A in the last 3 months\n* who have received treatments with dry needling in the last month\n* severe cognitive deficits\n* fear of needles\n* metal allergy.",{"count":214,"type":21},28,[24],"Stroke is a global health problem, with an incidence in Europe of 147\u002F100,000 people per year. It is estimated that 43% of them present spasticity throughout the first year, causing disability, hindering mobility and functionality, which can generate comorbidity problems, which in turn hinders its improvement over time.\n\nRecently, high quality studies have conclude that there is a moderate level of evidence with large effect size in reducing spasticity with dry needling, as well as being cost-effective in stroke patients in both the subacute and chronic phases. However, due to the limitation of manual evaluations of spasticity, and it is necessary to look for measurement alternatives that complement it, such as the analysis of the electromyographic activity and the muscular structure measured with ultrasound. These data could provide objective, useful and complementary information to clinical assessments to be more specific and effective in the treatment of stroke patients.\n\nThis randomized controlled trial aim to analyse the effect of dry needling in this parameters in patients with stroke and spasticity, as well as correlated with gait variables. Each participant will be randomly assigned to the dry needling group or to the sham dry needling group, where participants receive a total of 4 sessions of ultrasound-guided dry needling or sham ultrasound-guided dry needling in the gastrocnemius medialis over 4 weeks, one per week. Measures of spasticity, electromyographic activity and muscle structure via ultrasound will made at baseline (T0) and immediate after each intervention (T1,T2,T3,T4). Gait variables will be made at baseline and after the last intervention (T0 and T4).",[218],"Spasticity as Sequela of Stroke",[220,221,222,223,224,225],"Dry needling","Spasticity","Hypertonia","Surface electromyography","Diagnostic ultrasound","Gait",{"date":201,"type":39},{"date":228,"type":39},"2023-09-15",{"date":230,"type":21},"2026-09-15",{"name":45,"class":46},{"id":233,"slug":234,"hasResults":11,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":238,"eligibilityCriteria":239,"healthyVolunteers":11,"sex":16,"minAge":240,"maxAge":4,"enrollmentInfo":241,"targetDuration":4,"studyType":22,"phases":242,"briefSummary":243,"conditions":244,"keywords":248,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":259,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":75},"100606263","peer-mentorship-program-for-newly-graduated-occupational-therapists-in-aragn-mentoras-100606263","NCT07173283","Peer Mentorship Program for Newly Graduated Occupational Therapists in Aragón (MenTOras)","Evaluation of the Impact of a Peer Mentorship Program on the Professional Integration of Newly Graduated Occupational Therapists: The MenTOras Program","MenTOras","Inclusion Criteria (Mentees - Recently graduated occupational therapists):\n\n* Completed a degree in Occupational Therapy within the past 2 years.\n* May or may not be currently employed in the profession.\n* Registered member of the Aragon Professional Association of Occupational Therapists (COPTOA).\n\nInclusion Criteria (Mentors - Experienced occupational therapists):\n\n* Minimum of 5 years of clinical or community-based practice in occupational therapy.\n* Actively practicing at the time of enrollment.\n* Registered member of COPTOA.\n\nExclusion Criteria (applies to both groups unless otherwise specified):\n\n* For mentors: occupational therapists who are no longer actively practicing.\n* For all participants: current involvement in another mentorship program or structured training initiative with overlapping objectives.","21 Years",{"count":114,"type":21},[24],"This study evaluates the MenTOras program, a structured peer mentorship intervention designed for newly graduated occupational therapists in Aragón, Spain. The transition from university to professional practice can be challenging, and many new occupational therapists face isolation, limited guidance, and uncertainty about their professional role.\n\nThe MenTOras program connects newly graduated occupational therapists (mentees) with more experienced colleagues (mentors). Over a three-month period, mentor-mentee pairs participate in at least six structured sessions, either online or in person. These sessions are designed to support professional integration, strengthen self-confidence, promote reflective practice, and provide emotional support.\n\nThe study uses a mixed-methods approach. Quantitative data are collected before the program, after completion, and six months later to assess perceived professional integration, emotional well-being, and professional confidence. In addition, qualitative interviews with a subset of participants explore their experiences in greater depth.\n\nBy fostering peer support, MenTOras aims to improve the early career experience of occupational therapists and provide a model for sustainable mentoring practices within the profession.",[245,246,247],"Professional Integration of Newly Graduated Occupational Therapists","Peer Mentorship in Health Professions","Early Career Transition and Professional Identity",[249,250,251,252,253,254,255,256,257],"Occupational Therapy","Peer Mentorship","Professional Development","Newly Graduated Health Professionals","Early Career Support","Professional Identity","Job Satisfaction","Spain","Pilot Study","2025-09-08",{"date":260,"type":39},"2025-09-15",{"date":262,"type":39},"2025-08-01",{"date":264,"type":21},"2026-07-01",{"name":45,"class":46},{"id":267,"slug":268,"hasResults":11,"nctId":269,"briefTitle":270,"officialTitle":271,"acronym":4,"eligibilityCriteria":272,"healthyVolunteers":55,"sex":16,"minAge":4,"maxAge":273,"enrollmentInfo":274,"targetDuration":4,"studyType":22,"phases":276,"briefSummary":277,"conditions":278,"keywords":280,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":285,"lastUpdatePostDateStruct":286,"startDateStruct":288,"completionDateStruct":290,"leadSponsor":292,"locationsCount":4},"100599570","optimizing-hamstring-rehabilitation-with-amino-acids-100599570","NCT07086209","Optimizing Hamstring Rehabilitation With Amino Acids","Optimizing Hamstring Rehabilitation With Amino Acids: A Randomized Controlled Study for Seamless Return to Sports in Football Athletes","Inclusion Criteria:\n\n* • Male football players aged 18 to 35 years.\n\n  * Active players from eight clubs in the Iraqi Football League.\n  * MRI-confirmed partial hamstring muscle injury.\n  * No participation in other ongoing rehabilitation programs.\n\nExclusion Criteria:\n\n* • History of hamstring injury in the past six months.\n\n  * Any other musculoskeletal injuries affecting lower limbs.\n  * Contraindications for MRI scanning (e.g., metal implants, pacemakers).\n  * Any existing neurological or metabolic conditions affecting muscle recovery.","60 Years",{"count":275,"type":21},25,[24],"Hamstring injuries are among the most prevalent and troublesome injuries in athletes, particularly those engaged in sports that require high-speed movements such as sprinting, kicking, and rapid changes in direction. The hamstring muscles, which include the biceps femoris, semitendinosus, and semimembranosus, are essential for powerful lower limb actions, and thus, any injury to these muscles can significantly impact an athlete's performance and recovery. These injuries often occur during eccentric muscle contractions, such as when the muscles lengthen rapidly under tension, as seen in running and sprinting. According to epidemiological studies, hamstring strains account for a substantial portion of sports-related injuries, with hamstring strains being the most commonly reported injury in disciplines such as football, soccer, rugby, and athletics. In professional football, for instance, hamstring injuries account for approximately 12% of all injuries and represent the most frequent muscle strain, underlining their significance in the context of athletic performance.",[279],"Seamless Return to Sports",[281,282,283,284],"Hamstring Rehabilitation","Return to play","Amino Acids","Football","2025-07-18",{"date":287,"type":39},"2025-07-25",{"date":289,"type":21},"2025-09-19",{"date":291,"type":21},"2025-10-20",{"name":45,"class":46},{"id":294,"slug":295,"hasResults":11,"nctId":296,"briefTitle":297,"officialTitle":298,"acronym":299,"eligibilityCriteria":300,"healthyVolunteers":11,"sex":16,"minAge":301,"maxAge":4,"enrollmentInfo":302,"targetDuration":4,"studyType":22,"phases":304,"briefSummary":305,"conditions":306,"keywords":314,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":317,"lastUpdatePostDateStruct":318,"startDateStruct":320,"completionDateStruct":322,"leadSponsor":324,"locationsCount":75},"100598069","mindfulness-and-compassion-program-for-the-improvement-of-emotional-and-behavioral-problems-academic-performance-and-school-climate-in-students-in-the-last-cycle-of-primary-education-100598069","NCT07066696","Mindfulness and Compassion Program for the Improvement of Emotional and Behavioral Problems, Academic Performance and School Climate in Students in the Last Cycle of Primary Education.","Mindfulness and Compassion Program for the Improvement of Emotional and Behavioral Problems, Academic Performance and School Climate in Students in the Last Cycle of Primary Education (Cuida2 Project)","Cuida2","Inclusion Criteria:\n\n* To be a pupil, parent\u002Fguardian of a child or minor under guardianship or academic tutor in the 5th or 6th year of Primary Education.\n* Fluent in Spanish.\n* Provided informed consent.\n\nExclusion Criteria:\n\n* Participant's decision to withdraw from the study at any point","10 Years",{"count":303,"type":21},448,[24],"This randomized controlled trial aims to evaluate the efficacy of a Mindfulness and Compassion program to improve emotional and behavioral problems, academic performance and school climate of students in the last cycle of Primary Education.\n\nParticipants will be randomly assigned to the Cuida2 program or to an active control group practicing relaxation.\n\nThe different variables studied will be evaluated before and after the intervention, and at a three months follow-up. These evaluations will be carried out by the students and their families. In addition, a qualitative exploration will be carried out at the end of the programs, also including the teachers' perceptions.",[307,308,309,310,311,312,313],"Mindfulness","Compassion","Self-Compassion","Academic Performance","School Climate","Mental Health","Primary School Students",[307,308,315,313,316,311,310],"Self-compassion","Emotional and Behavioural Problems","2025-07-04",{"date":319,"type":39},"2025-07-15",{"date":321,"type":21},"2025-10-06",{"date":323,"type":21},"2027-01-30",{"name":45,"class":46},{"id":326,"slug":327,"hasResults":11,"nctId":328,"briefTitle":329,"officialTitle":330,"acronym":4,"eligibilityCriteria":331,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":332,"targetDuration":4,"studyType":22,"phases":334,"briefSummary":335,"conditions":336,"keywords":341,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":347,"lastUpdatePostDateStruct":348,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":353,"locationsCount":75},"100587143","motivational-training-program-for-pre-service-physical-education-teachers-100587143","NCT06924554","Motivational Training Program for Pre-service Physical Education Teachers","Study Protocol of a Non-randomized Controlled Trial on a Circumplex Model-based Motivational Training Program for Pre-service Physical Education Teachers","Inclusion Criteria:\n\n* Enrollment in the Master's in Physical Education Teacher Education at the University of Zaragoza.\n* 100% attendance in training sessions (experimental group).\n* Completion of questionnaires at three time points (pre-test, intermediate, and post-test).\n* Participation in the final focus group discussion.\n\nExclusion Criteria:\n\n* Failure to complete required assessments.\n* Lack of attendance in mandatory sessions.",{"count":333,"type":21},38,[24],"This study presents the protocol for a non-randomized controlled trial evaluating a motivational-based training program for pre-service Physical Education teachers. The experimental group will participate in a 14-hour training program based on Self-Determination Theory and the circumplex model. The program consists of theoretical and practical training to foster motivating teaching styles and minimize demotivating ones. The control group will follow the standard curriculum of the Master's in Physical Education Teacher Education program without exposure to the specific intervention.",[337,338,339,340],"Teaching Styles","Motivation","Competence","Pre-service Teachers",[342,343,344,345,346],"Self-Determination Theory","(de)motivating teaching styles","physical education teacher education","quasi-experimental study","mixed-methods research","2025-04-04",{"date":349,"type":39},"2025-04-11",{"date":351,"type":21},"2025-09",{"date":41,"type":21},{"name":45,"class":46},{"id":355,"slug":356,"hasResults":11,"nctId":357,"briefTitle":358,"officialTitle":359,"acronym":4,"eligibilityCriteria":360,"healthyVolunteers":55,"sex":16,"minAge":273,"maxAge":4,"enrollmentInfo":361,"targetDuration":4,"studyType":22,"phases":363,"briefSummary":364,"conditions":365,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":368,"lastUpdatePostDateStruct":369,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":375,"locationsCount":75},"100537553","effects-of-a-computerized-cognitive-stimulation-intervention-adapted-to-the-level-of-cognitive-reserve-100537553","NCT06279325","Effects of a Computerized Cognitive Stimulation Intervention Adapted to the Level of Cognitive Reserve","Analysis of the Effectiveness of a Computerized Cognitive Stimulation Program Designed from Occupational Therapy According to the Level of Cognitive Reserve in Older Adults in Primary Care: Stratified Randomized Clinical Trial Protocol","Inclusion Criteria:\n\n* Age: ≥ 60 years.\n* With score in Lobo's Mini-cognitive Examination (MEC-35) (Lobo, A., Escolar, V., Ezquerra, J., \\& Seva Díaz, 1979) between: 28-35 points (Friedman et al., 2012; Vinyoles Bargalló et al., 2002).\n* Non-institutionalized persons, belonging to the health centers where the study was conducted.\n* With a minimum educational level (knowing how to read and write).\n* Who do not present hearing, visual or communication difficulties that would prevent them from completing the cognitive training.\n\nExclusion Criteria:\n\n* People with mild cognitive impairment or Alzheimer's disease (AD).\n* People with significant functional impairment.\n* People who have received any type of professionalized cognitive stimulation therapy in the last year.\n* People with significant psychiatric conditions, such as major depressive disorder or schizophrenia.\n* People who are taking medications that may adversely affect cognitive function, such as anticholinergics, tranquilizers and anticonvulsants.",{"count":362,"type":21},100,[24],"Normal ageing presents subtle cognitive changes that can be detected before meeting the criteria for Mild cognitive impairment (MCI). Older people with low cognitive reserve and who receive limited cognitive stimulation are at greater risk of deterioration. In this regard, cognitive stimulation (CS) has been identified as an intervention that reduces this risk, provided that its design considers the differences in the level of cognitive reserve (CR) acquired throughout life and the baseline level of cognitive functioning. The general objective of this study is to evaluate, through a randomized clinical trial, the effectiveness of a computerized cognitive stimulation program, designed and adapted from Occupational Therapy based on the level of cognitive reserve in older adults in Primary Care. 100 participants will be randomized in a stratified manner according to the level of cognitive reserve (high\u002Flow), assigning 50 participants to the control group and 50 participants to the intervention group. The intervention group will carry out a computerized cognitive stimulation intervention designed and adapted from occupational therapy according to the level of cognitive reserve, through the \"stimulus\" platform. The main result expected to be achieved is the improvement of higher brain functions. As secondary results, the investigators expect that those cognitive aspects most vulnerable to ageing will decrease more slowly (in areas such as memory, executive function, attention and processing speed) and that the cognitive reserve of the participants will increase, in addition to being able to balance gender differences in these aspects. The investigators think that these results can positively impact the creation of adapted, meaningful and stimulating CS programs in older adults to prevent MCI and experience healthier ageing.",[366,367],"Mild Cognitive Impairment","Cognitive Dysfunction","2024-12-06",{"date":370,"type":39},"2024-12-12",{"date":372,"type":39},"2024-04-01",{"date":374,"type":21},"2025-01-15",{"name":45,"class":46},{"id":377,"slug":378,"hasResults":11,"nctId":379,"briefTitle":380,"officialTitle":381,"acronym":4,"eligibilityCriteria":382,"healthyVolunteers":55,"sex":16,"minAge":383,"maxAge":4,"enrollmentInfo":384,"targetDuration":4,"studyType":22,"phases":386,"briefSummary":387,"conditions":388,"keywords":391,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":368,"lastUpdatePostDateStruct":398,"startDateStruct":399,"completionDateStruct":400,"leadSponsor":402,"locationsCount":75},"100520595","effects-of-a-computerised-cognitive-stimulation-versus-stimulating-leisure-activities-100520595","NCT06058611","Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities","Effects of a Personalised and Tailored Computerised Cognitive Stimulation Programme Versus Stimulating Leisure Activities in Older Adults with Mild Cognitive Impairment and Subjective Cognitive Impairment: Randomised Controlled Trial","Inclusion Criteria:\n\n* ≥ 50 years old, resident in the community.\n* Diagnosis of MCI or having between 24 and 27 points on the MEC-35 (this score seems to indicate the presence of MCI) (Calero, M. D and Navarro, 2006).\n* Subjective cognitive impairment (score between 28-31 points on the MEC-35) (Gómez-Soria et al. 2023)\n\nExclusion Criteria:\n\n* Institutionalisation.\n* Taking acetylcholinesterase inhibitors as they may act on global cognition and\u002For cognitive functions.\n* Sensory deficits (deafness and blindness) preventing intervention.\n* Agitation.\n* Having received cognitive stimulation in the last 12 months.","50 Years",{"count":385,"type":21},90,[24],"The aim of the study is to evaluate, at the level of global cognition, cognitive neuroconstructs, memory, verbal fluency, ADLs, IADLs, symptoms of depression and anxiety, the effectiveness of a personalised and adapted computerised cognitive stimulation programme (GI1) implemented from Primary Care versus stimulating leisure activities (GI2), in older adults aged 50 years and over with mild cognitive impairment and subjective cognitive impairment living in the community.",[366,389,390],"Randomized Controlled Trial","Subjective Cognitive Impairment",[366,392,393,389,394,395,396,397,390],"Older adults","Elderly","Cognitive Stimulation","Cognitive Intervention","Cognitively Stimulating Leisure Activities","Leisure Activities",{"date":370,"type":39},{"date":372,"type":39},{"date":401,"type":21},"2025-09-30",{"name":45,"class":46},""]