[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidade Ceuma\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100641661","effect-of-enamel-cleaning-on-a-remineralizing-paste-for-hypomineralizated-lesions-100641661",false,"NCT07653373","Effect of Enamel Cleaning on a Remineralizing Paste for Hypomineralizated Lesions","The Effect Of Deproteinization On The Performance Of CPP-ACPF On Hypomineralized Enamel: A Clinical Evaluation","ECLIPSE","Inclusion Criteria:\n\n* Children must have at least one permanent molar without MIH, at least two permanent molars with mild MIH lesions (demarcated opacities without structural loss), with or without sensitivity, that are cream-white or yellowish in color and at least 2 mm in diameter. The teeth with lesions may or may not be on the same dental arch.\n\nExclusion Criteria:\n\n* Children with visible bacterial biofilm, enamel malformations associated with syndromes, amelogenesis imperfecta, or fluorosis, and children who are allergic to milk proteins (casein) will not be eligible to participate in the study.",true,"ALL","7 Years","9 Years",{"count":22,"type":23},54,"ESTIMATED","INTERVENTIONAL",[26],"NA","Molar-incisor hypomineralization (MIH) is a qualitative defect of dental enamel, in which low mineral content and high protein content compromise the effectiveness of remineralizing treatments. Various agents have been used to remove proteins from hypomineralized enamel, such as sodium hypochlorite (NaOCl). Sodium hypochlorite is an antimicrobial irrigant capable of dissolving tissues. CPP-ACPF is used as a remineralizing agent for MIH lesions, it is capable of stabilizing calcium, phosphate, and fluoride ions on the tooth surface, maintaining them in an amorphous form. Therefore, the objective of this study is to evaluate the clinical performance of amorphous calcium fluoride casein phosphate phosphopeptide (CPP-ACPF) dental mousse on deproteinized hypomineralized enamel.",[29],"Molar Incisor Hypomineralization",[31,32,33,34],"molar hypomineralization","dental enamel","spectrophotometry","dental remineralization","NOT_YET_RECRUITING","2026-06-11",{"date":38,"type":39},"2026-06-17","ACTUAL",{"date":41,"type":23},"2026-08",{"date":43,"type":23},"2028-04",{"name":45,"class":46},"Universidade Ceuma","OTHER",""]