[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidade do Estado do Pará\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":128},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,49,78,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100640150","effects-of-a-rehabilitation-protocol-on-muscle-strength-muscle-fatigue-and-postural-control-in-post-dengue-and-chikungunya-patients-100640150",false,"NCT07600879","Effects Of A Rehabilitation Protocol On Muscle Strength, Muscle Fatigue And Postural Control In Post-Dengue And Chikungunya Patients","Effects Of A Rehabilitation Protocol On Muscle Strength, Muscle Fatigue And Postural Control In Post-Dengue And Chikungunya Patients: Non-Randomized Clinical Trial","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Individuals of both sexes\n* Residents of the 1st, 4th, or 11th Health Regions of the state of Pará\n* Confirmed diagnosis of Dengue (DENV) and\u002For Chikungunya (CHIKV) infection by serological testing (ELISA or IgG\u002FIgM)\n* Diagnosis confirmed within the last 5 years\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Hemodynamic instability\n* Musculoskeletal instability, including fractures or acute muscle injuries\n* Cognitive deficits impairing the understanding of commands or study procedures\n* History of balance disorders prior to Dengue or Chikungunya infection\n* Obesity\n* Blindness or low vision\n* Hearing impairment","ALL","18 Years",{"count":19,"type":20},54,"ESTIMATED","INTERVENTIONAL",[23],"NA","Introduction: Dengue and Chikungunya arboviral diseases are considered major public health challenges in tropical regions due to high infection rates and the occurrence of musculoskeletal sequelae that impair strength, balance, and functionality. After the acute phase, symptoms such as fatigue, joint pain, muscle weakness, and postural instability are common, reducing quality of life and hindering social and occupational reintegration.Objective: To analyze the effects of a rehabilitation protocol on muscle fatigue, muscle strength, and postural control in post-Dengue and Chikungunya patients.Methods: This is a non-randomized clinical trial conducted at the Integrated Laboratory for Research and Care in Infectious and Sequelae Diseases (LabDIS\u002FUEPA). Individuals of both sexes, aged over 18 years, with a confirmed diagnosis of Dengue and\u002For Chikungunya within the last five years will be included. Data collection will include a clinical interview, surface electromyography of the flexor carpi radialis, tibialis anterior, lateral and medial gastrocnemius muscles, hydraulic and electronic dynamometry, manovacuometry, and baropodometry. The rehabilitation protocol will consist of twenty supervised sessions of aerobic, anaerobic, and respiratory exercises.Expected Results: Improvements in muscle strength, muscle fatigue, and postural control are expected following the intervention.Conclusion: The findings may support physiotherapeutic strategies aimed at improving strength, fatigue, and balance, expanding knowledge on the neuromuscular and respiratory consequences of arboviral diseases, and contributing to the development of evidence-based rehabilitation protocols, with potential positive impacts on healthcare delivery and public health policies.",[26,27],"Dengue","Chikungunya",[29,30,31,32,33,34,35],"dengue","Chikungunya Virus","Muscle Strength","Electromyography","Rehabilitation","Posture","Muscle Fatigue","NOT_YET_RECRUITING","2026-05-20",{"date":39,"type":40},"2026-05-26","ACTUAL",{"date":42,"type":20},"2026-07-01",{"date":44,"type":20},"2027-07-30",{"name":46,"class":47},"Universidade do Estado do Pará","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":21,"phases":61,"briefSummary":62,"conditions":63,"keywords":67,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":48},"100628197","tdcs-combined-with-constraint-induced-therapy-in-post-stroke-upper-limb-rehabilitation-100628197","NCT07458503","tDCS Combined With Constraint-Induced Therapy in Post-Stroke Upper Limb Rehabilitation","Effects of Transcranial Direct Current Stimulation Combined With Constraint-Induced Therapy on Upper Limb Motor Function in Individuals After Stroke: A Randomized Controlled Trial","tDCS-CIT Strok","Inclusion Criteria:\n\n* (1) present a clinical diagnosis of stroke confirmed by imaging examination and\u002For report issued by a neurologist; (2) are in the chronic phase of the lesion with an occurrence time greater than six months; (3) hemiparesis with brachial predominance, mild to moderate motor deficit in the affected upper limb defined by a score between 19 and 55 points on the FMA-UE; (4) have minimum joint integrity to perform the movements required in the protocol with an active range of motion of at least 20° of wrist extension, 10° of extension of the metacarpophalangeal and interphalangeal joints and 20° of elbow extension considering the standard position of 90° elbow flexion, measured with a Carci® goniometer; (5) demonstrate the ability to understand and follow simple commands on the Mini Mental State Examination (MMSE) (ANNEX II) with a score higher than 23 points for literate persons and lower than 15 points for illiterate persons.\n\nExclusion Criteria:(1) diagnosis of epilepsy; (2) intracranial metallic implants or implantable electronic devices; (3) contraindications to transcranial direct current stimulation (tDCS), including skin lesions on the scalp; (4) severe musculoskeletal limitations that prevent the execution of tasks; (5) history of recurrent stroke; (6) associated disabling musculoskeletal and neurological pathologies; (7) use of botulinum toxin in the previous three months; (8) uncontrolled systemic arterial hypertension or diabetes mellitus; (9) clinically relevant heart disease; (10) apraxia and aphasia of comprehension; (11) fracture and pain during movement or displacement of the affected limb, or pain related to shoulder subluxation. Those who feel uncomfortable, drop out of the research, do not respect the rules established in the Informed Consent Form (APPENDIX C), or do not attend the stages of the study will also be excluded.","40 Years","80 Years",{"count":60,"type":20},40,[23],"The objective of this clinical trial is to evaluate the effects of transcranial direct current stimulation (tDCS) combined with constraint-induced therapy (CIT) on upper limb motor recovery in individuals after stroke.\n\nThe main questions it aims to answer are:\n\nDoes the combination of tDCS and CIT improve upper limb motor function compared to CIT alone?\n\nDoes the combined intervention promote changes in muscle morphology and electromyographic activity?\n\nResearchers will compare the group receiving tDCS combined with constraint-induced therapy to the group receiving constraint-induced therapy alone to determine whether the addition of cortical neuromodulation enhances motor recovery outcomes.\n\nThis is a randomized, controlled, and blinded clinical trial in which participants will be divided into two groups: one group will receive tDCS combined with CIMT, and the other will undergo only CIMT. The protocol will include 18 sessions over six weeks, three times a week.\n\nClinical and instrumental assessments will be performed before, during, and after the intervention, including the Fugl-Meyer scale for the upper limb, musculoskeletal ultrasound for morphological analysis, and surface electromyography for muscle activity assessment.",[64,65,66],"Stroke","Upper Limb Motor Impairment","Post-Stroke Hemiparesis",[64,68,69],"Transcranial Direct Current Stimulation","Upper Limb","2026-03-03",{"date":72,"type":40},"2026-03-09",{"date":74,"type":20},"2026-04-15",{"date":76,"type":20},"2027-04-10",{"name":46,"class":47},{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":21,"phases":86,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":48},"100624908","functional-assessment-and-pulmonary-rehabilitation-challenges-and-perspectives-for-comprehensive-care-100624908","NCT07415746","Functional Assessment and Pulmonary Rehabilitation: Challenges and Perspectives for Comprehensive Care","Inclusion Criteria:\n\n* Age 40 years or older.\n* Both sexes are eligible (men and women).\n* Clinically diagnosed COPD, clinically stable, classified in Stages I, II, III or IV of GOLD (Global Initiative for Chronic Obstructive Lung Disease).\n* Ability to understand and provide the signed Informed Consent Form to participate in the study.\n\nExclusion Criteria:\n\n* Physical limitations and\u002For cognitive impairment that prevent the execution of the study protocol.\n* Currently engaged in physical therapy treatment and\u002For physical activity that may interfere with the study results.\n* Presence of severe, uncontrolled, or disabling comorbidities.",{"count":85,"type":20},46,[23],"Individuals with Chronic Obstructive Pulmonary Disease (COPD) present with respiratory muscle dysfunction, characterized by reduced diaphragmatic contractility and mobility due to pulmonary hyperinflation, oxidative stress, and systemic inflammation. Effective assessment of diaphragmatic function is crucial for monitoring progress in pulmonary rehabilitation programs. This study aims to evaluate diaphragmatic function and mobility in COPD patients undergoing pulmonary rehabilitation with inspiratory muscle training, using ultrasound, and to identify associations between diaphragmatic dysfunction and clinical symptoms such as dyspnea and fatigue. A randomized clinical trial will be conducted to investigate the impact of rehabilitation on diaphragmatic function, correlating it with pulmonary function and physical performance.",[89],"Pulmonary Disease, Chronic Obstructive",[89,33,91,92],"Ultrasonography","Breathing Exercises","2026-02-09",{"date":95,"type":40},"2026-02-17",{"date":97,"type":20},"2026-03",{"date":99,"type":20},"2026-10",{"name":46,"class":47},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":109,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":21,"phases":113,"briefSummary":114,"conditions":115,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":4},"100596495","effects-os-physiotherapeutic-rehabilitation-on-function-autonomic-and-inflammatory-in-patients-with-long-covid-100596495","NCT07046208","Effects os Physiotherapeutic Rehabilitation on Function Autonomic and Inflammatory in Patients With Long Covid","Effects os Physiotherapeutic Rehabilitation on Cardiovascular Autonomic Modulation and Biomarkers Inflammatory and Cardiac Conditions in Patients With Long Covid","LongCovidRehab","Inclusion Criteria:\n\n* both sexes\n* aged 20 and 59 years\n* clinical evaluation and undergoing clinical follow-up of Post COVID-19.\n* least one persistent COVID-19-related symptom.\n\nExclusion Criteria:\n\n* incomplete data.\n* presence of a pacemaker\n* use of antihypertensive drugs that alter HRV\n* persistent pulmonary alterations\n* persistent desaturation\n* anaemia or presence of reinfection.","20 Years","59 Years",{"count":112,"type":20},58,[23],"Introduction: Long COVID is characterized by persistent symptoms that persist for weeks or months after the acute phase of infection, with a significant impact on the cardiovascular and autonomic systems. Objectives: This study aims to evaluate the effects of a physiotherapeutic rehabilitation protocol on cardiovascular autonomic modulation and on inflammatory and cardiac biomarkers in patients with Long COVID. Methodology: This is a controlled clinical trial, carried out in a cardiorespiratory rehabilitation outpatient clinic, involving individuals with a clinical diagnosis of Long COVID undergoing a protocol of 20 aerobic, anaerobic and respiratory rehabilitation sessions. Heart rate variability (HRV) variables will be analyzed using linear and non-linear methods, in addition to serum levels of CKMB, LDH, ferritin and C-reactive protein. Expected results: Rehabilitation is expected to provide an improvement in autonomic function and a reduction in inflammatory and cardiac markers, contributing to the understanding of the pathophysiological mechanisms of Long COVID and helping to propose evidence-based therapeutic strategies.",[116,117,118,119],"Long COVID","Heart Rate Variability (HRV)","Cardiac Biomarkers","Inflammatory Biomarkers","2025-06-29",{"date":122,"type":40},"2025-07-01",{"date":124,"type":20},"2025-08-11",{"date":126,"type":20},"2026-09-30",{"name":46,"class":47},""]