[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universiti Putra Malaysia\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":679},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,30,0,25,[9,47,82,110,136,171,193,225,250,276,299,324,348,375,413,439,464,484,511,537,567,589,611,632,650],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100642727","a-just-in-time-digital-learning-platform-for-teacher-oral-health-training-100642727",false,"NCT07645612","A Just-in-Time Digital Learning Platform for Teacher Oral Health Training","A Just-in-Time Digital Learning Platform for Teacher Oral Health Training: Effects on Oral Health Literacy, Implementation, and Student Oral Health Outcomes in a Randomized Controlled Trial","Inclusion Criteria: Teachers aged ≥18 years. Currently employed in participating schools. Access to a smartphone, tablet, or computer with internet connectivity. Able to understand the intervention language. Willing to provide informed consent and participate in study activities. -\n\nExclusion Criteria: Currently participating in another oral health training program or research study.\n\nPlanning to leave employment at the participating school during the study period.\n\nUnable to access or use the digital learning platform. Refusal or withdrawal of informed consent.\n\n\\-",true,"ALL","18 Years","65 Years",{"count":22,"type":23},870,"ESTIMATED","INTERVENTIONAL",[26],"NA","This randomized controlled trial aims to evaluate the effectiveness and implementation of a Just-in-Time Digital Learning Platform designed to improve teachers' oral health literacy and support the delivery of oral health education in schools. Teachers play an important role in promoting healthy behaviors among children, but many have limited access to structured oral health training. Digital microlearning approaches may provide a scalable and cost-effective solution for strengthening teacher capacity in school-based oral health promotion.\n\nTeachers assigned to the intervention group will receive access to a digital learning platform that delivers short, interactive, and evidence-based oral health training modules through mobile devices. The platform will provide educational content, reminders, quizzes, feedback, and progress monitoring. Teachers in the control group will receive standard information or routine training practices.\n\nThe study will assess changes in teachers' oral health literacy, knowledge, attitudes, and confidence in delivering oral health education. It will also evaluate implementation outcomes, including acceptability, feasibility, adoption, fidelity, reach, and engagement with the digital platform. In addition, the study will examine whether improvements in teacher training lead to better oral health knowledge, behaviors, and clinical oral health outcomes among students.",[29,30,31],"Oral Health Behavior Change","Oral Hygiene, Oral Health","Digital Literacy",[33],"Oral Health Literacy; Digital Learning; Teacher Training; Implementation Outcomes; Health Equity","NOT_YET_RECRUITING","2026-06-08",{"date":37,"type":38},"2026-06-12","ACTUAL",{"date":40,"type":23},"2026-06-15",{"date":42,"type":23},"2026-10-30",{"name":44,"class":45},"Universiti Putra Malaysia","OTHER",1,{"id":48,"slug":49,"hasResults":12,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":17,"sex":18,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":24,"phases":59,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},"100617987","effectiveness-of-a-remind-diet-intervention-on-sarcopenia-cognitive-frailty-and-nutritional-status-in-older-adults-100617987","NCT07325760","Effectiveness of a ReMIND Diet Intervention on Sarcopenia, Cognitive Frailty and Nutritional Status in Older Adults","1. Translating MY-MINDD Into Practice: Retort Meal Interventions to Improve Muscle Health, Nutritional Status, and Food Security Among Malaysian Older Adults 2. Effectiveness of ReMIND Diet- Based Retort Meal Intervention on Cognitive Frailty in Low-Income Malaysian Older Adults: A Cluster Randomised Controlled Trial","ReMIND","Inclusion Criteria:\n\n* Malaysian older adults aged 60 to 84 years.\n* Classified under the B40 income group.\n* Preferably living independently, without receiving daily meals from family members; cohabitation with other older adults is acceptable if meal support is not provided.\n* Experiencing food insecurity as assessed by screening questionnaires.\n* Able to provide informed consent.\n* Participate in the study for the full duration.\n* Able to stand without support.\n* For older adults living with a spouse, preferably both partners must be eligible, willing to participate, and recruited for the study.\n\nExclusion Criteria:\n\n* Individuals with diagnosed terminal illnesses (e.g., cancer, end-stage liver failure, end-stage lung disease, and severe form of heart diseases) and having medical conditions requiring specialized dietary restrictions (e.g., chronic\u002Fend-stage renal disease, severe dysphagia).\n* Those with cognitive impairments or disabilities that prevent them from understanding the study procedures or providing consent.\n* Participants or their spouse enrolled in other nutrition-related intervention programs during the study period.\n* Those unwilling or unable to adhere to the intervention protocol.\n* Bedridden\n* Handicapped or amputated\n* Wearing pacemaker\n* Vegetarian, food allergies or food intolerance","60 Years","84 Years",{"count":58,"type":23},70,[26],"This research is a single-blinded, 12-week, two-arm cluster randomized controlled trial to evaluate the effectiveness of a Malaysian-adapted MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet retort meal intervention on sarcopenia risk, cognitive frailty status, nutritional status, depression, functional ability, and food security among older adults in Malaysia. With Malaysia projected to become an aged society by 2030, addressing age-related health challenges, including cognitive frailty and sarcopenia, is a national priority. Current evidence indicates that poor diet quality and food insecurity among older adults, especially those in low-income urban communities, exacerbate these conditions. The study is grounded on the Meals on Wheels (MoW) program, which has been effective in reducing malnutrition among older populations globally but is limited in scalability due to high delivery costs. Retort meals which are shelf-stable and nutritionally balanced offer a feasible alternative for meal provision in poor urban settings. The MIND diet, originally designed to support brain health, also demonstrates benefits for muscle health and overall physical function. However, its adaptation to the Malaysian context is crucial due to cultural dietary preferences and cost barriers to certain ingredients. The intervention will recruit 70 older adults (aged 60-84 years) from Program Perumahan Rakyat (PPR) Seri Alam Fasa 2 and Perumahan Awam (PA) Loke Yew in Kuala Lumpur, classified under the B40 income group and at risk of food insecurity. The intervention group will receive retort meals designed according to the adapted MIND diet principles, while the control group will not receive intervention. Data will be collected at baseline, 6 weeks, and 12 weeks to assess outcomes in muscle health, cognitive frailty, nutritional status, depression, functional ability, food security, and cost-effectiveness. Overall, the conceptual framework provides a structured approach to understanding how the intervention contributes to improved nutritional well-being and supports the economic viability of the Meals on Wheels program. Potential confounding variables, including socioeconomic status, baseline health conditions, social support, and lifestyle factors, may also influence the outcomes. Participants will fill up a questionnaire regarding their sociodemographic characteristics, medical factors, psychological factors, lifestyle factors, food security status, functional ability, and depression status. Besides, the researcher will conduct face-to-face interviews to collect data regarding anthropometric measurements, handgrip strength, medical costs, and diet history. Statistical analyses will employ mixed-effects models to evaluate both continuous and categorical outcomes over time. The findings will generate crucial evidence on the feasibility, effectiveness, and cost-efficiency of using retort meals within MoW programs in Malaysia. Furthermore, it will inform national strategies to address food insecurity, promote healthy ageing, and reduce the burden of age-related health conditions. With Malaysia's rapidly ageing population and increasing prevalence of sarcopenia and cognitive frailty, this study has the potential to shape policy and practice by offering a sustainable, culturally tailored nutrition intervention. The evidence derived will support the scaling up of MoW programs using retort meals and contribute to long-term solutions for improving the quality of life and independence of older adults in Malaysia.",[62,63,64],"Sarcopenia","Cognitive Frailty","Nutritional Interventions",[66,67,68,69,70,71,72,73],"older adults","sarcopenia","cognitive","cognitive frailty","malnutrition","mind diet","my-mindd","nutrition intervention","2026-06-04",{"date":76,"type":38},"2026-06-05",{"date":40,"type":23},{"date":79,"type":23},"2027-02-26",{"name":44,"class":45},2,{"id":83,"slug":84,"hasResults":12,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":90,"enrollmentInfo":91,"targetDuration":4,"studyType":24,"phases":92,"briefSummary":93,"conditions":94,"keywords":97,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":46},"100643605","satiety-evaluation-of-mature-okra-flour-incorporated-biscuit-100643605","NCT07631663","Satiety Evaluation of Mature Okra Flour-incorporated Biscuit","Evaluating the Impact of Mature Okra Flour-Incorporated Biscuits (MOFB) on Perceived Satiety Through the Satiety Labeled Intensity Magnitude (SLIM) Scale and Metabolomic Approach","MOFB","Inclusion Criteria:\n\n* Young adults aged between 18 and 39 years.\n* Normal Body Mass Index (BMI).\n\nExclusion Criteria:\n\n* Smokers.\n* Pregnant or lactating women.\n* Individuals with daily medication prescriptions for chronic metabolic conditions, cardiovascular management, or hormonal regulation.\n* Use of daily medications\u002Fsupplements that influence appetite regulation, metabolic signalling, or systemic metabolomic profiles, including:\n\n  1. Hormonal contraceptives, glucocorticoids, and oral\u002Finjectable anti-obesity medications (e.g., GLP-1 agonists).\n  2. Antihypertensives and lipid-lowering agents (statins).\n  3. Chronic Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).\n  4. Daily fibre supplements.","39 Years",{"count":5,"type":23},[26],"This study aims to evaluate whether eating biscuits made with mature okra flour can help young adults feel fuller (enhance satiety) and change certain blood markers compared to eating standard biscuits.\n\nMature okra is a nutrient-dense agricultural by-product that is often discarded due to its tough texture. For this study, mature okra pods are dried and ground into a flour, which is then used to replace 10% of the wheat flour in a custom biscuit formulation.\n\nParticipants will take part in a single-blind, randomised trial where they will consume either the okra-incorporated biscuits or the standard control biscuits on separate occasions. Researchers will measure participants' perceived fullness over 165 minutes using a visual rating scale. Blood samples will also be collected at specific intervals during this time to evaluate blood glucose levels, appetite-related hormones, and metabolic responses.",[95,96],"Appetite Regulation","Healthy Young Adults",[98,99,100,101],"Satiety response","Blood glucose response","Hormonal change","Metabolomic analysis","RECRUITING","2026-06-03",{"date":35,"type":38},{"date":106,"type":38},"2026-05-15",{"date":108,"type":23},"2026-06-25",{"name":44,"class":45},{"id":111,"slug":112,"hasResults":12,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":24,"phases":118,"briefSummary":119,"conditions":120,"keywords":123,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":133,"leadSponsor":135,"locationsCount":46},"100637384","cost-effectiveness-of-a-re-aim-informed-autonomy-competence-intervention-to-improve-medication-adherence-and-quality-of-life-among-patients-with-heart-failure-100637384","NCT07580508","Cost-effectiveness of a RE-AIM-Informed Autonomy-Competence Intervention to Improve Medication Adherence and Quality of Life Among Patients With Heart Failure","Cost-effectiveness of a RE-AIM-Informed Autonomy-Competence Intervention to Improve Medication Adherence, Health-related Quality of Life, and Implementation Outcomes Among Patients With Heart Failure: a Hybrid Effectiveness-implementation Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥18 years\n\n  * Diagnosed heart failure for at least 6 months\n  * Prescribed ≥2 heart failure medications\n  * Documented medication non-adherence\n  * Able to provide informed consent\n  * Access to a smartphone\n\nExclusion Criteria:\n\n* Severe psychiatric illness\n* Terminal illness\n* Severe cognitive impairment\n* End-stage renal disease\n* Participation in another intervention trial",{"count":22,"type":23},[26],"Medication non-adherence leads to recurrent admissions, worsening symptoms, poor quality of life, and increased healthcare costs in an already overburdened health system. Existing adherence interventions in Pakistan are limited, mostly educational, and rarely guided by behavioural theory, implementation science, or economic evaluation.\n\nTherefore, a culturally appropriate, RE-AIM-informed autonomy-competence intervention is needed to improve medication adherence and quality of life among heart failure patients in Pakistan, while also assessing implementation feasibility and cost-effectiveness for future scale-up.",[121,122],"Heart Failure","Chronic Heart Failure (CHF)",[124,125,126,127,128],"Chronic Heart Failure","Medication adherence","Cost-effectiveness","Randomized controlled trial","RE-AIM","2026-05-06",{"date":131,"type":38},"2026-05-12",{"date":106,"type":23},{"date":134,"type":23},"2026-09-15",{"name":44,"class":45},{"id":137,"slug":138,"hasResults":12,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":4,"eligibilityCriteria":142,"healthyVolunteers":17,"sex":143,"minAge":19,"maxAge":4,"enrollmentInfo":144,"targetDuration":4,"studyType":24,"phases":146,"briefSummary":147,"conditions":148,"keywords":155,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":170},"100578742","enhancing-maternal-vaccine-knowledge-and-uptake-the-introduce-programme-trial-100578742","NCT06815250","Enhancing Maternal Vaccine Knowledge and Uptake: The InTroDuce-Programme Trial","Effectiveness of the Influenza and Tdap (Tetanus, Diphtheria, Acellular Pertussis) Vaccination Educational and Learning Module (InTroDuce-Programme) in Improving Knowledge and Future Uptake of Vaccination Among Pregnant Mothers in Primary Care Clinics: A Randomised Control Trial Secondary IDs","Inclusion Criteria:\n\n* Pregnant women aged 18 years and older\n* Before or equal to 32 weeks of gestation as we need to follow-up the patients again at 36 weeks of gestation before delivery occurs.\n* Able to understand and consent to participation in the study.\n\nExclusion Criteria:\n\n* Pregnant women with severe anaphylactic or allergic reactions to previous dose of influenza or Tdap vaccination.\n* Non-Malaysian","FEMALE",{"count":145,"type":23},351,[26],"The goal of this InTroDuce-Programme interventional trial aims to test whether a web-based educational program can improve pregnant women's knowledge about Influenza and Tdap vaccinations and increase their intention to get vaccinated in the future. The main questions it aims to answer are:\n\nDoes the InTroDuce-Programme increase knowledge and future intention of pregnant mothers to get vaccinated against Influenza and Tdap? How does demographic factors, attitudes and barriers affect vaccination decisions among pregnant mothers?\n\nResearchers will compare InTroDuce-Programme to standard care (routine antenatal care) to see if InTroDuce-Programme works to improve knowledge and future intention of pregnant mothers to be vaccinated against Influenza and Tdap. Participants will:\n\nReceive the web-based educational module (InTroDuce-Programme), which covers the importance, safety, and effectiveness of vaccinations, as well as addressing common concerns.\n\nBe followed up one month after the intervention. Answer questionnaires before and after the intervention to measure changes in vaccination knowledge and future intention to get vaccinated",[149,150,151,152,153,154],"Vaccination Uptake","Knowledge","Tetanus, Diphtheria and Acellular Pertussis Vaccination","Influenza","Web Based Intervention","Vaccine Knowledge",[156,157,158,159,160,161],"Influenza vaccination","Tdap vaccination","Educational module","Pregnant mothers","Vaccine knowledge","Vaccine uptake","2026-04-27",{"date":164,"type":38},"2026-05-01",{"date":166,"type":38},"2026-01-13",{"date":168,"type":23},"2026-06",{"name":44,"class":45},4,{"id":172,"slug":173,"hasResults":12,"nctId":174,"briefTitle":175,"officialTitle":176,"acronym":4,"eligibilityCriteria":177,"healthyVolunteers":17,"sex":18,"minAge":178,"maxAge":20,"enrollmentInfo":179,"targetDuration":4,"studyType":24,"phases":181,"briefSummary":182,"conditions":183,"keywords":4,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":46},"100627329","the-effectiveness-of-ergonomics-intervention-program-to-reduce-the-risk-factors-of-musculoskeletal-100627329","NCT07447219","The Effectiveness of Ergonomics Intervention Program to Reduce the Risk Factors of Musculoskeletal","The Effectiveness of Ergonomics Intervention Program to Reduce the Risk Factors of Musculoskeletal Symptoms Among Dubai Healthcare Workers in Dubai (UAE)","Inclusion Criteria:\n\n* Dental healthcare workers currently active in their professional roles.\n* Minimum of one year of professional experience to ensure adequate occupational exposure.\n* Age range between 25 and 65 years to focus on the working-age population most at risk.\n* Consent to participate in the study.\n\nExclusion Criteria:\n\n* Individuals on extended leave or not currently practicing.\n* History of upper limb injuries unrelated to work.\n* Presence of neurological or rheumatological conditions.\n* Severe systemic diseases such as multiple sclerosis or stage II hypertension.\n* Recent surgeries involving the neck or shoulder.\n* Pregnancy.","25 Years",{"count":180,"type":23},110,[26],"This study evaluates an ergonomics intervention to reduce work-related musculoskeletal disorders (MSDs) among dental healthcare workers in Dubai government hospitals, where up to 90% prevalence affects the lower back, neck, shoulders, and upper extremities due to repetitive tasks and postures. Using a cluster randomized controlled trial (RCT) across three hospitals (55 participants per intervention\u002Fcontrol group), it assesses MSD prevalence\u002Fseverity, mental health, physical activity, and KAP scores at baseline, post-intervention, and three-month follow-up. Analyses include logistic regression, ANOVA, and GEE. Expected outcomes: identify predictors and demonstrate intervention efficacy via education, environmental, and behavioral changes, informing UAE occupational health policies.",[184],"Work-related Musculoskeletal Disorders","2026-02-25",{"date":187,"type":38},"2026-03-03",{"date":189,"type":38},"2024-03-01",{"date":191,"type":23},"2027-03-30",{"name":44,"class":45},{"id":194,"slug":195,"hasResults":12,"nctId":196,"briefTitle":197,"officialTitle":198,"acronym":199,"eligibilityCriteria":200,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":55,"enrollmentInfo":201,"targetDuration":4,"studyType":24,"phases":203,"briefSummary":204,"conditions":205,"keywords":208,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":217,"lastUpdatePostDateStruct":218,"startDateStruct":220,"completionDateStruct":222,"leadSponsor":224,"locationsCount":46},"100621066","internet-based-group-cbt-for-anxiety-and-depression-among-international-students-100621066","NCT07365787","Internet-Based Group CBT for Anxiety and Depression Among International Students","Effectiveness of Internet-Based Group Cognitive Behaviour Therapy (GCBT) for Anxiety and Depression Among International Students Studying in Malaysia: A Randomized Controlled Trial","DARE Program","Inclusion Criteria:\n\n* International students.\n* 18 and 60 years of age.\n* Moderate to severe symptoms of anxiety and depression.\n* Fluent in the English language.",{"count":202,"type":23},128,[26],"The goal of this RCT trial is to learn if internet-based group cognitive behaviour therapy delivered via the Zoom application works to treat anxiety and depression among international students. It will also learn about the predictive factors of the intervention's effectiveness. The main questions it aims to answer are:\n\n* Does participating in internet-based GCBT reduce the symptoms of anxiety among international students in Malaysia?\n* Does participating in internet-based GCBT reduce the symptoms of depression among international students in Malaysia?\n\nResearchers will compare students who take part in the intervention program with students in a waitlist control group to understand whether the intervention is associated with changes in anxiety and depression symptoms.\n\nParticipants will:\n\n* Be randomly assigned to either the intervention program or a waitlist control group\n* Attend four sessions of one hour each, including 1) psychoeducation, 2) cognitive techniques, 3) behaviour techniques, and 4) support and relapse prevention. A booster session and a follow-up assessment will be done1 month post intervention.",[206,207],"Anxiety","Depression",[206,207,209,210,211,212,213,214,215,216],"Anxiety and Depression","Internet-based Group Cognitive Behaviour Therapy","Internet-based Group CBT","Internet-based Group CBT Intervention","iGCBT","Internet-based GCBT","International Students","University Students","2026-01-28",{"date":219,"type":38},"2026-01-30",{"date":221,"type":23},"2026-06-01",{"date":223,"type":23},"2027-08-31",{"name":44,"class":45},{"id":226,"slug":227,"hasResults":12,"nctId":228,"briefTitle":229,"officialTitle":230,"acronym":4,"eligibilityCriteria":231,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":232,"enrollmentInfo":233,"targetDuration":4,"studyType":24,"phases":235,"briefSummary":236,"conditions":237,"keywords":239,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":242,"lastUpdatePostDateStruct":243,"startDateStruct":245,"completionDateStruct":247,"leadSponsor":249,"locationsCount":46},"100606907","the-effectiveness-of-intermittent-fasting-caloric-restriction-and-physical-activity-on-metabolic-syndrome-100606907","NCT07181655","The Effectiveness of Intermittent Fasting, Caloric Restriction and Physical Activity On Metabolic Syndrome","The Effectiveness of Intermittent Fasting, Caloric Restriction and Physical Activity Intervention On Metabolic Syndrome Biomarkers Among Adults With Metabolic Syndrome at Hospitals in Riyadh, Saudi Arabia","Inclusion Criteria:\n\n* The inclusion criteria will be adult aged 18 years and above who have three or more of the following five risk factors (Kunduraci \\& Ozbek, 2020):\n\n  * Abdominal obesity.\n  * Elevated triglycerides.\n  * Low HDL cholesterol.\n  * Elevated blood pressure.\n  * Elevated fasting blood glucose.\n\nExclusion Criteria:\n\n* Being pregnant, lactating women.\n* Diagnosis of cardiac failure or\u002Fand severe renal or liver diseases, cancer.\n* Having had bariatric surgery.\n* Physical or mental disability.\n* Neurological or cognitive impairment.\n* Participant with severely impaired vision, hearing, or speech.\n* Following a special diet or having changed their dietary pattern within the previous 12 weeks of the study's start date.\n* Use of insulin or sulphonamide derivative oral antidiabetic drugs.\n* Conditions that will seriously affect weight management such as having had bariatric surgery.","80 Years",{"count":234,"type":23},140,[26],"Metabolic syndrome (MetS) is a global health issue defined by a cluster of risk factors-abdominal obesity, elevated blood pressure, high fasting blood sugar, high triglycerides, and low HDL cholesterol-that together significantly increase the risk of cardiovascular disease, type 2 diabetes, and overall mortality. Globally, about 20-25% of adults are affected, but prevalence varies by region and population; in Saudi Arabia, studies report rates ranging from 28.3% to 56.4%, with higher rates observed in northern and central regions and among men. Major contributors to MetS in Saudi Arabia include obesity, sedentary lifestyle, smoking, and poor dietary habits, such as low fruit consumption. Effective management strategies focus on weight loss through caloric restriction, intermittent fasting, and increased physical activity, all of which have demonstrated improvements in metabolic markers like insulin sensitivity, blood pressure, and lipid profiles. Despite international evidence supporting these interventions, no randomized controlled trials have yet evaluated the combined effects of these approaches on MetS biomarkers in Saudi adults, underscoring the need for targeted research and public health initiatives to address the high and regionally variable burden of MetS in the country.",[238],"Metabolic Syndrome",[240,241],"metabolic syndrome","MetS","2025-09-18",{"date":244,"type":38},"2025-09-24",{"date":246,"type":38},"2025-04-01",{"date":248,"type":23},"2027-12-30",{"name":44,"class":45},{"id":251,"slug":252,"hasResults":12,"nctId":253,"briefTitle":254,"officialTitle":255,"acronym":256,"eligibilityCriteria":257,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":258,"targetDuration":4,"studyType":24,"phases":260,"briefSummary":261,"conditions":262,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":268,"lastUpdatePostDateStruct":269,"startDateStruct":271,"completionDateStruct":273,"leadSponsor":275,"locationsCount":46},"100606403","rct-to-evaluate-the-efficacy-of-the-nsscep-in-reducing-burnout-among-jordanian-pediatric-oncology-nurses-100606403","NCT07175103","RCT to Evaluate the Efficacy of the NSSCEP in Reducing Burnout Among Jordanian Pediatric Oncology Nurses","Nurses' Self-Care Educational Programme (NSSCEP)","NSSCEP","Inclusion Criteria:\n\n1. A registered nurse (RN) employed in a paediatric oncology unit in for at least 6 months.\n2. Willingness to participate in all aspects of the study, including interventions, questionnaires, and follow-up assessments.\n3. Ability to understand and communicate in English\n4. Have ability Self-reported experience of burnout related to their role as a paediatric oncology nurse.\n5. Nurses provide informed consent\n\nExclusion Criteria:\n\n1. Less than six months of experience in paediatric oncology\n2. Non-registered nurses (e.g., nursing assistants or technicians)\n3. Non-voluntary participation or inability to provide informed consent\n4. Inability to communicate in English\n5. Involvement in leadership roles or administrative positions",{"count":259,"type":23},80,[26],"The goal of this clinical trial is to learn if the Nurses' Stress Self-Care Educational Program (NSSCEP) can reduce burnout and occupational stress in Jordanian pediatric oncology nurses. The main questions it aims to answer are:\n\n1. Does NSSCEP reduce symptoms of burnout in pediatric oncology nurses?\n2. Does NSSCEP improve stress management skills among pediatric oncology nurses? Researchers will compare nurses participating in the NSSCEP to a control group receiving a general technical skills program to see if NSSCEP reduces burnout and improves stress management.\n\nParticipants will:\n\n1. Attend four educational sessions over one month, focusing on stress recognition, coping strategies, and resilience-building techniques\n2. Complete weekly checklists to track their application of stress management skills\n3. Participate in pre- and post-intervention surveys to assess burnout and stress levels",[263,264,265,266,267],"Paediatric Oncology","Nurses","Burnout","Occupational Stress","Self Care","2025-09-11",{"date":270,"type":38},"2025-09-16",{"date":272,"type":23},"2025-09",{"date":274,"type":23},"2025-11",{"name":44,"class":45},{"id":277,"slug":278,"hasResults":12,"nctId":279,"briefTitle":280,"officialTitle":281,"acronym":4,"eligibilityCriteria":282,"healthyVolunteers":17,"sex":18,"minAge":283,"maxAge":284,"enrollmentInfo":285,"targetDuration":4,"studyType":24,"phases":287,"briefSummary":288,"conditions":289,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":292,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":170},"100603672","a-digital-intervention-to-improve-oral-health-practices-100603672","NCT07139561","A Digital Intervention to Improve Oral Health Practices","Oral Health in Hands: A Digital Intervention to Improve Oral Health Practices in Children","Inclusion Criteria:\n\n* Parents or primary caregivers of children aged 6-10 years.\n* Child must be free from major systemic illnesses or developmental disabilities that could interfere with oral hygiene practices.\n* Parent\u002Fcaregiver owns a smartphone with access to WhatsApp or similar digital platform.\n* Ability to read or understand Urdu or English instructions.\n* Willingness to participate for the full 12-week duration and provide informed consent.\n\nExclusion Criteria:\n\n* Children with serious medical conditions (e.g., immunodeficiency, congenital anomalies) that may affect oral health.\n* Parents or children currently enrolled in another oral health education or digital intervention program.\n* Children who have received professional oral health education or structured interventions within the past 4 months.\n* Parents\u002Fcaregivers unwilling or unable to comply with digital reporting and participation requirements.","6 Years","10 Years",{"count":286,"type":23},800,[26],"This study evaluates a 16-week parent-focused digital intervention to improve oral health practices in children aged 6-10 through daily reminders, quizzes, challenges, gamification, and behavior tracking, supported by an optional moderated WhatsApp group for peer engagement and motivation.",[290,29],"Digital Intervention","2025-08-17",{"date":293,"type":38},"2025-08-24",{"date":295,"type":23},"2025-08-18",{"date":297,"type":23},"2026-02-18",{"name":44,"class":45},{"id":300,"slug":301,"hasResults":12,"nctId":302,"briefTitle":303,"officialTitle":304,"acronym":305,"eligibilityCriteria":306,"healthyVolunteers":12,"sex":143,"minAge":19,"maxAge":232,"enrollmentInfo":307,"targetDuration":4,"studyType":24,"phases":309,"briefSummary":310,"conditions":311,"keywords":314,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":316,"lastUpdatePostDateStruct":317,"startDateStruct":319,"completionDateStruct":321,"leadSponsor":323,"locationsCount":46},"100519112","perioperative-immunonutrition-under-enhanced-recovery-after-surgery-100519112","NCT06039306","Perioperative Immunonutrition Under Enhanced Recovery After Surgery","Perioperative Immunonutrition Among Gynecological Cancer Patients Under Enhanced Recovery After Surgery","PING-ERAS","Inclusion Criteria:\n\n1. Those who diagnosed with GC\n2. Candidates for elective operation treatments\n\nExclusion Criteria:\n\n1. Those are involved gastrointestinal tract (complication)\n2. Those are diagnosed with GC (metastasis)\n3. Allergy to milk\u002Fsoy\u002Fwhey protein\n4. Participate in other intervention study",{"count":308,"type":23},106,[26],"The goal of this clinical trial is to compare the effect of perioperative immunonutrition supplement in gynecologic cancer patients. The main questions it aims to answer are:\n\n* is there any difference in the nutritional outcomes and functional outcomes between intervention and conventional groups?\n* is there any difference in the post-surgical outcomes between intervention and conventional groups?\n\nParticipants (intervention) will be provided the immunonutrition supplement before and after operation.\n\nResearchers will compare intervention group with conventional group to see if there is any difference in postoperative outcomes.",[312,313],"Gynecological Cancer","Elective Surgery",[315],"gynecological cancer, elective surgery","2025-08-13",{"date":318,"type":38},"2025-08-19",{"date":320,"type":38},"2024-09-01",{"date":322,"type":23},"2025-10-30",{"name":44,"class":45},{"id":325,"slug":326,"hasResults":12,"nctId":327,"briefTitle":328,"officialTitle":329,"acronym":4,"eligibilityCriteria":330,"healthyVolunteers":17,"sex":18,"minAge":283,"maxAge":331,"enrollmentInfo":332,"targetDuration":4,"studyType":24,"phases":334,"briefSummary":335,"conditions":336,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":339,"lastUpdatePostDateStruct":340,"startDateStruct":342,"completionDateStruct":344,"leadSponsor":346,"locationsCount":347},"100601817","effectiveness-of-school-based-oral-health-intervention-for-children-100601817","NCT07115433","Effectiveness of School-based Oral Health Intervention for Children","Effectiveness of a School-Based Oral Health Promotion Program on Oral Health Practices, Behaviour, Self-Efficacy, and Clinical Outcomes Among Primary School Children: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Children aged 6-8 years enrolled in selected schools\n* Written informed consent from parents\u002Fguardians and assent from children\n\nExclusion Criteria:\n\n* Children with systemic conditions affecting oral health\n* Those currently in other oral health interventions","8 Years",{"count":333,"type":23},600,[26],"Schools provide an ideal setting for early interventions. Evidence suggests that educational programs incorporating behavioural change theories can improve oral hygiene practices and clinical outcomes.\n\nA School-Based Oral Health Promotion Program on Oral Health Practices, Behaviour, Self-Efficacy, and Clinical Outcomes Among Primary School Children for six months, while the control group will receive no intervention, only routine care.",[337,338],"Oral","Health","2025-08-03",{"date":341,"type":38},"2025-08-11",{"date":343,"type":23},"2025-08-05",{"date":345,"type":23},"2026-02-10",{"name":44,"class":45},3,{"id":349,"slug":350,"hasResults":12,"nctId":351,"briefTitle":352,"officialTitle":353,"acronym":4,"eligibilityCriteria":354,"healthyVolunteers":17,"sex":355,"minAge":284,"maxAge":356,"enrollmentInfo":357,"targetDuration":4,"studyType":24,"phases":359,"briefSummary":360,"conditions":361,"keywords":363,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":368,"lastUpdatePostDateStruct":369,"startDateStruct":371,"completionDateStruct":372,"leadSponsor":374,"locationsCount":46},"100593636","impact-of-oral-health-program-on-al-lith-childrens-kap-100593636","NCT07009015","Impact of Oral Health Program on Al-Lith Children's KAP","The Effect Of Health Education Intervention Program In Improving Knowledge, Attitude, And Practice Of Oral Health Among Male Primary School Children In Al-Lith Saudi Arabia: A Clustered Randomised Control Trial","Inclusion Criteria:\n\n* Primary school male students.\n* Aged 10 to 11 years old.\n* Students who have at least one of their parent's consents to participate in the study.\n\nExclusion Criteria:\n\n* Students who are medically ill at the time of conducting the study.\n* Students that are absent while conducting the study.","MALE","11 Years",{"count":358,"type":23},430,[26],"Dental caries remains a significant global public health issue, particularly affecting children's health, development, and well-being, with inadequate knowledge, attitudes, and practices around oral health exacerbating these impacts. To address this, a cluster randomized controlled trial will be conducted in four primary schools in Al Lith City, Saudi Arabia, targeting children aged 10 to 11 years. The intervention involves interactive, classroom-based educational sessions led by a dental care professional, supplemented by take-home materials, focusing first on enhancing knowledge and attitudes, and then on developing behavioral skills for improved oral hygiene and eating habits. Participants' knowledge, attitudes, and practices will be assessed via questionnaires before, immediately after, and six months post-intervention, with data analyzed using SPSS through descriptive statistics, chi-square tests, One Way-ANOVA, and Generalized Estimating Equations. The study expects that school-based oral health education will significantly improve children's oral health knowledge and certain hygiene behaviors, as well as positively influence eating habits and patterns.",[362],"Dental Caries in Children",[364,365,150,366,367],"Dental caries","Oral health status","Attitude","Practice","2025-07-09",{"date":370,"type":38},"2025-07-15",{"date":189,"type":38},{"date":373,"type":23},"2027-08-30",{"name":44,"class":45},{"id":376,"slug":377,"hasResults":12,"nctId":378,"briefTitle":379,"officialTitle":380,"acronym":4,"eligibilityCriteria":381,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":382,"targetDuration":4,"studyType":24,"phases":384,"briefSummary":385,"conditions":386,"keywords":391,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":405,"lastUpdatePostDateStruct":406,"startDateStruct":408,"completionDateStruct":410,"leadSponsor":412,"locationsCount":46},"100589627","clinical-effectiveness-of-mynutrikidney-100589627","NCT06956872","Clinical Effectiveness of MyNutriKidney®","Clinical Effectiveness of MyNutriKidney® for Dietary Self-management in Chronic Kidney Disease Patients: Protocol for a Pragmatic Randomized Controlled Trial","Participants must meet all of the following inclusion criteria and none of the exclusion criteria to be eligible for enrolment into the study.\n\nInclusion Criteria:\n\n1. Clinically diagnosed Chronic Kidney Disease (CKD):\n\n   1.1. eGFR \\\u003C 60 ml\u002Fmin\u002F1.73m² for ≥ 3 months (applicable to pre-dialysis patients, Stages 3-5)\n2. Aged 18 years or older.\n3. Possesses a personal smartphone compatible with the MyNutriKidney® application and is willing to use the health app if randomized to the intervention group.\n4. Alert and oriented, and deemed capable of providing informed consent and participating in study procedures.\n5. Able to communicate and understand study procedures in English, Bahasa Melayu, or Mandarin.\n\nExclusion Criteria:\n\n1. Inability to effectively use the smartphone application due to significant impairments (e.g., severe visual or motor problems).\n2. Smartphone owned by the participant does not meet the minimum technical requirements for the MyNutriKidney® application installation and operation\n3. Presence of significant cognitive impairment or severe psychological conditions (e.g., uncontrolled anxiety or depression) likely to impede consistent participation or adherence to study requirements.\n4. Known unwillingness or inability to comply with core study procedures, including dietary assessment components.\n5. Concurrent participation in another interventional research study.\n6. Participation in another research study involving an investigational product in the 12 weeks preceding potential enrollment.\n7. Female participants who are pregnant, currently lactating, or planning a pregnancy during the course of the trial.\n8. Currently receiving primary nutritional support via enteral tube feeding or parenteral (intra-venous) nutrition.\n9. Currently receiving active treatment for cancer (e.g., chemotherapy, radiotherapy).",{"count":383,"type":23},200,[26],"This study is a 6-month, pragmatic, multi-center, sequentially recruited, stratified, open-label randomized controlled trial (RCT) conducted in Malaysia. It aims to determine the clinical effectiveness of a culturally adapted, gamified mobile health app (MyNutriKidney®) supplementing standard care, compared to standard care alone, for improving dietary self-management among 200 adults with Chronic Kidney Disease (CKD) stages 3-5. Participants will be randomly assigned (1:1, stratified by age and education) into either (i) the intervention group (MyNutriKidney® app + standard care) or (ii) the control group (standard care, including routine dietary counseling and printed materials). The co-primary outcomes are changes in Dietary Adherence (measured by CKD Diet Score) and Nutrition Literacy (measured by NLS score) from baseline to 6 months.",[387,388,389,390],"Chronic Kidney Disease Stage 3","Chronic Kidney Disease","Chronic Kidney Disease Stage 5","Chronic Kidney Disease Stage 4",[392,393,394,395,396,397,398,399,400,401,402,403,404],"MyNutriKidney","chronic kidney disease","CKD","Dietary Adherence","Nutrition Literacy","Self-management","Mobile Health","Dietitian","mHealth","Telemedicine","Digital Health","Malaysia","Kidney Diseases","2025-05-01",{"date":407,"type":38},"2025-05-04",{"date":409,"type":23},"2025-07-01",{"date":411,"type":23},"2027-02-01",{"name":44,"class":45},{"id":414,"slug":415,"hasResults":12,"nctId":416,"briefTitle":417,"officialTitle":418,"acronym":4,"eligibilityCriteria":419,"healthyVolunteers":17,"sex":18,"minAge":55,"maxAge":4,"enrollmentInfo":420,"targetDuration":4,"studyType":24,"phases":421,"briefSummary":422,"conditions":423,"keywords":425,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":431,"lastUpdatePostDateStruct":432,"startDateStruct":434,"completionDateStruct":436,"leadSponsor":438,"locationsCount":46},"100488232","peer-supported-diabetes-self-care-intervention-to-improve-health-related-quality-of-life-hrqol-and-diabetes-management-100488232","NCT05637437","Peer-Supported Diabetes Self-Care Intervention to Improve Health Related Quality of Life (HRQoL) and Diabetes Management","Peer-Supported Diabetes Self-Care Intervention to Improve Health Related Quality of Life (HRQoL) and Diabetes Management in Elderly With Type 2 Diabetes (T2DM): A Randomized Control Trial","Inclusion Criteria:\n\n* Age must be 60 years or more\n* Diagnosed with T2DM by physician minimum for more than 1 year\n* The ability to communicate in Malay or English language properly\n* The ability to perform daily activities independently\n* No major complications (e.g.- dementia, blind, deaf)\n* Planned to continue receiving care at this clinic for next 6 months\n* Participated at the usual education session\n* Access to a smart phone with internet\n\nExclusion Criteria:\n\n* Debilitating medical or related condition (e.g. end-stage cancer, severe mental illness)\n* Physical inability to provide self-care",{"count":202,"type":23},[26],"Diabetes mellitus is the ninth leading cause of mortality worldwide. Diabetes is a chronic condition with a major impact on the life and well-being of individuals, families, and societies globally. The three main types of diabetes are type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), and gestational diabetes mellitus (GDM); approximately 90% of the total cases accounts for T2DM. T2DM is characterized by chronic hyperglycaemia and affects 9.5% of adults aged 20-99 years. The highly burdensome condition is predominantly prevalent in elderly population and distresses 19.3% of elderly aged 65-99 years. Elderly with diabetes have poor Health related Quality of Life (HRQoL) in comparison with their peers of similar age from the general populations.\n\nThe determinants of poor HRQoL in elderly with T2DM diabetes population are - poor glycemic control, long duration of diabetes, multiple co-morbidities, depression, high body mass index (BMI), poor self-management practices, higher diabetes related distress, low social support and increased social isolation. Diabetes Self-management Education and Support (DSME\u002FS) is a critical element of care to improve the overall condition of diabetic patients. Self-care does play a critical role in elderly diabetes management. The goal of the current clinical trial is to develop and assess the effectiveness of peer supported diabetes self-care intervention in improving the HRQoL in elderly with type 2 diabetes.",[424],"Type 2 Diabetes Mellitus",[426,427,428,429,430],"Elderly","T2DM","HRQoL","Peer Support","Diabetes Management","2025-03-31",{"date":433,"type":38},"2025-04-03",{"date":435,"type":23},"2025-06-01",{"date":437,"type":23},"2026-12-31",{"name":44,"class":45},{"id":440,"slug":441,"hasResults":12,"nctId":442,"briefTitle":443,"officialTitle":444,"acronym":4,"eligibilityCriteria":445,"healthyVolunteers":17,"sex":143,"minAge":19,"maxAge":446,"enrollmentInfo":447,"targetDuration":4,"studyType":24,"phases":449,"briefSummary":450,"conditions":451,"keywords":4,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":456,"lastUpdatePostDateStruct":457,"startDateStruct":459,"completionDateStruct":461,"leadSponsor":463,"locationsCount":46},"100582526","breastfeeding-relaxation-intervention-among-mothers-of-preterm-infants-in-hospital-sultan-abdul-aziz-shah-hsaas-100582526","NCT06864455","Breastfeeding Relaxation Intervention Among Mothers of Preterm Infants in Hospital Sultan Abdul Aziz Shah (HSAAS)","\"Effects of a Relaxation Intervention on Physiological and Psychological Outcomes Among Mothers of Preterm Infants At Hospital Sultan Abdul Aziz Shah : a Within-subject Randomized Trials\"","Inclusion Criteria ( Mothers)\n\n* Malaysian women of reproductive age (18-49 years)\n* Muslim\n* Non-smoker\n* Understand English or Malay\n* Currently breastfeed their infants\n* Mothers of infants born in gestational age (28 weeks- 35 weeks)\n* No medical conditions that can affect infant feeding.\n\nExclusion Criteria:\n\n* Taking psychiatric medication and being diagnosed with mental illness.\n* Mothers are on medication that contradicts breastfeeding (eg: under medication HIV\u002FAIDS)\n* Plan to formula feed or mix feeding their infants.\n* Mothers of infants with illness that could affect breastfeeding and growth (respiratory issues, gastrointestinal issues, feeding difficulties, neurological disorder, etc)","49 Years",{"count":448,"type":23},15,[26],"This study is designed to compare the effects of four relaxation interventions on both physiological and psychological outcomes in lactating mothers of preterm infants. The interventions being tested include:\n\n* Guided Imagery Meditation (GIM)\n* Religious Recitation (RR)\n* Infant Video with Music\n* Distraction with News and Media\n* A Control session\n\nThe primary objectives of the study are to evaluate and compare how these different relaxation techniques influence the physiological and psychological well-being of mothers and identify which intervention is most effective for lactating mothers who deliver prematurely.\n\nThe main research questions are:\n\n1. How do different interventions (GIM, RR, Infant Video with Music, Distraction with Media, and Control) affect physiological and psychological outcomes when measured within the same participants?\n2. Are there significant differences in physiological and psychological outcomes when participants are exposed to different interventions (GIM, RR, Infant Video with Music, Distraction with Media, and Control) within the same group?\n3. Among the interventions, which one demonstrates the most beneficial effects on physiological and psychological outcomes within the same participants?\n\nStudy Design:\n\nEach participant will be exposed to five different sessions (one for each intervention), with a gap of 1-2 days between sessions. The interventions will be administered as follows:\n\n* Guided Imagery Meditation (GIM)\n* Religious Recitation (RR)\n* Infant Video with Music\n* Distraction with News and Media\n* A Control session\n\nExpected Outcomes:\n\nThis study will assess the following physiological and psychological outcomes:\n\nPhysiological changes:\n\n* Heart Rate (HR)\n* Systolic Blood Pressure (SBP)\n* Diastolic Blood Pressure (DBP)\n* Fingertip Temperature (FT)\n* Breast milk cortisol concentration\n\nPsychological changes:\n\n•. Perceived Relaxation",[452,453,454,455],"Behaviour","Psychology","Physiology","Therapy","2025-03-03",{"date":458,"type":38},"2025-03-07",{"date":460,"type":38},"2024-09-17",{"date":462,"type":23},"2026-08-21",{"name":44,"class":45},{"id":465,"slug":466,"hasResults":12,"nctId":467,"briefTitle":468,"officialTitle":469,"acronym":4,"eligibilityCriteria":470,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":232,"enrollmentInfo":471,"targetDuration":4,"studyType":24,"phases":473,"briefSummary":474,"conditions":475,"keywords":4,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":477,"lastUpdatePostDateStruct":478,"startDateStruct":480,"completionDateStruct":481,"leadSponsor":483,"locationsCount":46},"100582373","impact-of-an-intervention-education-program-on-the-knowledge-attitudes-and-practices-of-dietitians-100582373","NCT06862466","Impact of an Intervention Education Program on the Knowledge, Attitudes, and Practices of Dietitians","Impact Of An Intervention Education Program On The Knowledge, Attitudes, And Practices Of Dietitians Working With Chronic Kidney Disease Patients In Public Hospitals Of Saudi Arabia","Inclusion Criteria:\n\n* Dietitians who worked with chronic kidney disease patients.\n* Dietitians who registered in Saudi Commission for Health Specialties.\n* Completed at least one-year experience in their job.\n* Dietitians who agree to participate in the study.\n* Dietitians who are available at the time of data collection.\n\nExclusion Criteria:\n\n* Medical doctor dietitians.\n* Internship and student.\n* Dietitians under one-year experience.",{"count":472,"type":23},100,[26],"This study aims to develop, implement, and evaluate an educational program-based intervention on the knowledge, attitude, and practice toward renal nutrition among dietitians working with chronic kidney disease (CKD) patients in public hospitals in Saudi Arabia. The study hypothesizes that there will be a significant improvement in the knowledge, attitude, and practice of renal nutrition among the dietitians in the intervention group compared to the control group after the implementation of the educational program. The findings will contribute to enhancing the ability of dietitians to provide effective nutritional care and support for CKD patients in Saudi Arabia.",[476],"No Conditions","2025-03-02",{"date":479,"type":38},"2025-03-06",{"date":189,"type":38},{"date":482,"type":23},"2025-12-30",{"name":44,"class":45},{"id":485,"slug":486,"hasResults":12,"nctId":487,"briefTitle":488,"officialTitle":489,"acronym":4,"eligibilityCriteria":490,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":491,"enrollmentInfo":492,"targetDuration":4,"studyType":24,"phases":494,"briefSummary":495,"conditions":496,"keywords":498,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":503,"lastUpdatePostDateStruct":504,"startDateStruct":506,"completionDateStruct":508,"leadSponsor":510,"locationsCount":4},"100575916","effect-of-plyometric-training-on-university-student-latin-dancers-lower-limbs-explosive-strength-and-skill-performance-100575916","NCT06778499","Effect of Plyometric Training on University Student Latin Dancers' Lower Limbs Explosive Strength and Skill Performance","Effect of Plyometric Training on Lower Limbs Explosive Strength and Skill Performance Among University Student Latin Dancer in China","Inclusion Criteria:\n\n1. Have at least one year and more hours of Latin dance study.\n2. Must be a current university student.\n\nExclusion Criteria:\n\n1. Athletes who were systematically training their explosive strength.\n2. Athletes with sports injuries such as ankle or waist injuries who could not follow the entire training schedule for two months.","30 Years",{"count":493,"type":23},48,[26],"The purpose of this study is to find out if plyometric training has an effect on lower limb explosive strength and skill performance in Latin dancers.\n\nThe aim is to answer the following questions:\n\n1. Does augmented style training increase dancers' lower limb explosive strength.\n2. Whether plyometric training promotes specialized dance skills.\n3. The relationship between lower limb explosive strength and specialized dance skills.\n\nThe researchers set up an experimental group and a control group, the experimental group uses plyometric training and the control group performs traditional training, and finally, between-group and within-group comparisons are made.\n\nParticipants will:\n\nTrain for 90 minutes three times a week for eight weeks. Participants' lower limb explosive strength and skills will be measured before the start of the experiment and at the end of the experiment.",[497],"Physical Education and Training\u002FMethods",[499,500,501,502],"plyometric training","Explosive strength","Latin dancer","Latin dance performance","2025-01-17",{"date":505,"type":38},"2025-01-22",{"date":507,"type":23},"2025-03-01",{"date":509,"type":23},"2025-05-05",{"name":44,"class":45},{"id":512,"slug":513,"hasResults":12,"nctId":514,"briefTitle":515,"officialTitle":516,"acronym":4,"eligibilityCriteria":517,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":55,"enrollmentInfo":518,"targetDuration":4,"studyType":24,"phases":520,"briefSummary":521,"conditions":522,"keywords":524,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":530,"lastUpdatePostDateStruct":531,"startDateStruct":533,"completionDateStruct":535,"leadSponsor":536,"locationsCount":46},"100507044","the-role-of-plant-based-omega-3-fatty-acids-and-molecular-characterisation-in-individuals-with-cardiovascularcvd-risk-100507044","NCT05882266","The Role of Plant-Based Omega-3 Fatty Acids and Molecular Characterisation in Individuals With Cardiovascular(CVD) Risk","The Role of Plant-Based Omega-3 Fatty Acids and Molecular Characterisation in Individuals With Cardiovascular(CVD) Risk at Beacon Hospital in Selangor","Inclusion Criteria:\n\n* Malaysian aged 18 to 60 years\n* BMI between 18.5 and 39.9 kg\u002Fm2\n* Not on any weight loss therapy\n* Is able to commit to 12 weeks of either intervention\n* Presented signs of metabolic syndrome or moderate hypercholesterolemia\n\nExclusion Criteria:\n\n* Those who are pregnant or lactating\n* Had undergone bariatric surgery\n* Who have acute illnesses such as flu\n* Who has any diabetes-related chronic complications except hypertension and hyperlipidemia\n* Having chronic diseases in particular cancer, liver, kidney, heart disease, stroke, or psychiatric illness\n* Having eating disorder or hypothyroidism",{"count":519,"type":23},72,[26],"The goal of this clinical trial is to investigate the outcome of plant-based omega-3 intervention on lipid profile and blood pressure after 12 weeks and to study the molecular markers associated with the incidence of CVD risk. The main questions it aims to answer are:\n\n* What is the role of plant-based omega-3 intervention on lipid profile and blood pressure of individuals with CVD risk after 12 weeks?\n* What is the association between unique molecular markers and plant-based omega-3 intervention among individuals with CVD risk?\n\nParticipants will be subjected to two groups:\n\n* Treatment group: Receive standard dietary therapy and plant-based omega-3 supplemental beverage consumed once daily during breakfast\n* Control group: Receive only standard dietary therapy\n\nResearcher will compare between treatment and control group to see the effect of plant based omega-3 on lipid profile and blood pressure after 12 weeks",[523],"Cardiovascular Risk",[525,526,527,528,529],"cvd risk","cardiovascular risk","plant omega","plant based omega 3","omega 3","2024-12-11",{"date":532,"type":38},"2024-12-16",{"date":534,"type":23},"2024-12-20",{"date":482,"type":23},{"name":44,"class":45},{"id":538,"slug":539,"hasResults":12,"nctId":540,"briefTitle":541,"officialTitle":542,"acronym":4,"eligibilityCriteria":543,"healthyVolunteers":17,"sex":143,"minAge":19,"maxAge":544,"enrollmentInfo":545,"targetDuration":4,"studyType":546,"phases":4,"briefSummary":547,"conditions":548,"keywords":555,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":559,"lastUpdatePostDateStruct":560,"startDateStruct":562,"completionDateStruct":564,"leadSponsor":566,"locationsCount":46},"100433065","mother-infant-cohort-study-in-malaysia-and-china-100433065","NCT04919265","Mother-Infant Cohort Study in Malaysia and China","Breastmilk, Infant Gut Microbiome and the Impact on Infant Health: a Prospective Mother-Infant Cohort Study in Malaysia and China","Inclusion Criteria:\n\n* Pregnant women aged between 18 and 45 years old\n* Pregnant women who attend the antenatal check-up at the selected clinics\u002Fhospitals\n* Pregnant women with the gestational age of less than 12 weeks\n* Pregnant women who plan to attend post-natal check-ups for at least one year at the same clinic\u002Fhospital\n\nExclusion Criteria:\n\n* Pregnant women who are diagnosed with immune deficiency\n* Pregnant women who have a multiple pregnancy and preterm delivery (\\\u003C37 weeks)\n* Pregnant women who plan to move out of the study area in the next one year\n* Pregnant women with fetal\u002Fnewborn with congenital abnormalities","45 Years",{"count":383,"type":23},"OBSERVATIONAL","This mother-infant cohort study aims to determine the geographic differences in the microbial profiles in breast milk from mothers living in Malaysia and China that are potentially important determinants of infant development. It also aims to determine the impact of gut microbiome on infant health (temperament, gastrointestinal symptoms, eczema symptoms, and asthma symptoms).",[549,550,551,552,553,554],"Gut Microbiota","Gastrointestinal Symptoms","Temperament","Eczema","Asthma","Breast Milk Collection",[556,557,558],"Gut microbiota","Mother-infant cohort study","Breastmilk","2024-12-09",{"date":561,"type":38},"2024-12-13",{"date":563,"type":38},"2022-06-03",{"date":565,"type":23},"2026-12",{"name":44,"class":45},{"id":568,"slug":569,"hasResults":12,"nctId":570,"briefTitle":571,"officialTitle":572,"acronym":4,"eligibilityCriteria":573,"healthyVolunteers":12,"sex":18,"minAge":574,"maxAge":575,"enrollmentInfo":576,"targetDuration":4,"studyType":24,"phases":577,"briefSummary":578,"conditions":579,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":581,"lastUpdatePostDateStruct":582,"startDateStruct":584,"completionDateStruct":586,"leadSponsor":588,"locationsCount":4},"100566331","psychosocial-stimulations-and-treatment-outcome-of-severe-acute-malnourished-children-100566331","NCT06653790","PSYCHOSOCIAL STIMULATIONS AND TREATMENT OUTCOME OF SEVERE ACUTE MALNOURISHED CHILDREN","EFFECT OF PSYCHOSOCIAL STIMULATIONS ON TREATMENT OUTCOME OF SEVERE ACUTE MALNOURISHED CHILDREN","Inclusion Criteria:\n\n* All children aged 6m to 59 months admitted to stabilization centre fulfilling criteria of severe acute malnutrition will be included in study.\n\nExclusion Criteria:\n\n* Children with chronic diseases like cystic fibrosis, cerebral palsy, celiac disease, chronic kidney disease, chronic liver failure, congenital heart disease, inborn error of metabolism, cleft lip and palate will be excluded from study.","6 Months","59 Months",{"count":286,"type":23},[26],"A playroom and a playground are already part of the stabilization unit and are furnished with basic facilities for engaging the SAM children in play-based motor, language, and personal-social activities. The severely acute malnourished children in the intervention group will be sent to a development pediatrician who will do a developmental assessment of the child and stimulation. A sensory therapist, an occupational therapist, and a physiotherapist will also be available for sessions.",[580],"Malnutrition Severe","2024-10-21",{"date":583,"type":38},"2024-10-22",{"date":585,"type":23},"2024-11-10",{"date":587,"type":23},"2025-04-10",{"name":44,"class":45},{"id":590,"slug":591,"hasResults":12,"nctId":592,"briefTitle":593,"officialTitle":594,"acronym":4,"eligibilityCriteria":595,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":596,"enrollmentInfo":597,"targetDuration":4,"studyType":24,"phases":599,"briefSummary":600,"conditions":601,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":603,"lastUpdatePostDateStruct":604,"startDateStruct":606,"completionDateStruct":608,"leadSponsor":610,"locationsCount":46},"100563293","advance-health-mobile-app-for-the-self-management-of-diabetes-type2-100563293","NCT06614283","Advance Health Mobile APP for the Self Management of Diabetes type2","Effectiveness of Advance Health Mobile APP for the Self Management of Diabetes type2 in a Resource-constrained Setting, a Randomized Control Trial","Inclusion Criteria:\n\n* The presence of T2D and at least 1 recorded HbA1c level of 8.0% or higher in the past 6 months\n* Age between ages 21 and 85 years,\n* Receiving primary care at the clinical site\n* Having fluency in English\u002F Urdu in reading and writing\n* Having a smartphone\n* Agreeing to take part in the study\n\nExclusion Criteria:\n\n* Planning to move away from the study site\n* Being pregnant or in lactation, (6) being unable to send or read text messages on a mobile phone,\n* Having a history of receiving or planning surgery.","85 Years",{"count":598,"type":23},1600,[26],"Digital health using mobile health (mHealth) tools, such as telehealth and text messaging, and or mobile Apps can improve blood glucose levels in patients with type 2 diabetes. This intervention is designed to improve self-management of diabetes and blood glucose levels in diabetic patients.",[602],"Diabetes Mellitus Type 2","2024-09-23",{"date":605,"type":38},"2024-09-26",{"date":607,"type":23},"2024-10-05",{"date":609,"type":23},"2025-06-10",{"name":44,"class":45},{"id":612,"slug":613,"hasResults":12,"nctId":614,"briefTitle":615,"officialTitle":616,"acronym":4,"eligibilityCriteria":617,"healthyVolunteers":12,"sex":143,"minAge":19,"maxAge":20,"enrollmentInfo":618,"targetDuration":4,"studyType":24,"phases":619,"briefSummary":621,"conditions":622,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":625,"lastUpdatePostDateStruct":626,"startDateStruct":628,"completionDateStruct":630,"leadSponsor":631,"locationsCount":4},"100561448","phase-4-evaluating-the-effects-of-adjunctive-aripiprazole-on-weight-and-metabolic-outcomes-in-females-100561448","NCT06590298","Evaluating the Effects of Adjunctive Aripiprazole on Weight and Metabolic Outcomes in Females","Evaluating the Effects of Adjunctive Aripiprazole on Weight and Metabolic Outcomes in Females Receiving Atypical Antipsychotics: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Females aged 18-65 years diagnosed with a mental health condition necessitating antipsychotic treatment.\n* Diagnosis of Schizophrenia or Schizoaffective Disorder\n* On stable doses of atypical antipsychotics, either Olanzapine, Clozapine, or Risperidone for at least 1 month\n* Willingness to comply with the study protocol.\n\nExclusion Criteria:\n\n* Pregnancy or lactation.\n* Severe medical conditions impacting weight or metabolism.\n* Previous intolerance or contraindications to Aripiprazole.\n* Non-compliant with prescribed medications\n* Mental Retardation\n* Participant with an eating disorder\n* Participants with serious suicidal thoughts, or who pose a serious risk of harm to self or to others.\n* Diagnosis of Hyper or Hypothyroidism; Evidence of thyroid dysfunction as evidenced by serum thyroid function tests (i.e Thyroid Stimulating Hormone and -Free Thyroxine (fT4) levels \\> 10 % above or below the limits of the normal range Use of any medication for weight loss within the past one month to the study entry\n* Clinically significant abnormalities in physical examinations, ECG or lab assessments",{"count":333,"type":23},[620],"PHASE4","Patients with psychiatric disorders, including depression, anxiety, and schizophrenia, often require antipsychotic medications for symptom management. However, metabolic changes, especially weight gain, are a common and challenging side effect of many antipsychotics. Aripiprazole, an atypical antipsychotic, has shown promise in mitigating this adverse effect when used in combination with other antipsychotic medications.",[623,238,624],"Psychosis","Weight Gain","2024-09-06",{"date":627,"type":38},"2024-09-19",{"date":629,"type":23},"2024-09-15",{"date":587,"type":23},{"name":44,"class":45},{"id":633,"slug":634,"hasResults":12,"nctId":635,"briefTitle":636,"officialTitle":637,"acronym":4,"eligibilityCriteria":638,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":232,"enrollmentInfo":639,"targetDuration":4,"studyType":24,"phases":641,"briefSummary":642,"conditions":643,"keywords":4,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":625,"lastUpdatePostDateStruct":645,"startDateStruct":646,"completionDateStruct":648,"leadSponsor":649,"locationsCount":46},"100561465","date-seed-extract-effectiveness-in-controlling-diabetes-and-cardiovascular-risk-in-t2dm-100561465","NCT06590519","Date Seed Extract Effectiveness in Controlling Diabetes and Cardiovascular Risk in T2DM","The Effectiveness of Date Seed Extract in Controlling Diabetes and Reducing Cardiovascular Risk in Patients With Type 2 Diabetes in Riyadh, Saudi Arabia","Inclusion Criteria:\n\n* Aged 18 years old and above.\n* Diagnosis of Type 2 diabetes.\n* Receiving and monitoring diabetes care from diabetes center.\n* With stable HbA1c less than 10% (no episode of hypoglycaemia, no hospitalisation, no change in type or dosage of medication use for at least 6 months).\n\nExclusion Criteria:\n\n* Pregnant or lactating women.\n* Diagnosis of cardiac failure or\u002Fand severe renal disease, with physical or mental disability, neurological or cognitive impairment.\n* Participant with severely impaired vision, hearing, or speech.\n* Participants who have known allergy to dates products.",{"count":640,"type":23},160,[26],"Globally, chronic noncommunicable diseases rank as the leading cause of morbidity and mortality. Diabetes is reaching high epidemic proportions across the globe. The prevalence of diabetes is increasing in Saudi Arabia, with diabetes affecting 14.1% of the population across all age groups and 28% of those over the age of 30. Date seed intake is one of the best-studied patterns. Previous studies findinds showed that the phenolic compounds in date seeds have blood sugar-lowering properties. There is a lack of data on how date seed diets may affect glycaemia control and cardiovascular risk among Saudi Arabian patients with T2DM. Therefore, randomised controlled trials (RCTs) will be conducted to assess the effects of date seeds on glycaemic control and cardiovascular risk among diabetes patients.",[424,644],"Obesity",{"date":627,"type":38},{"date":647,"type":38},"2024-07-01",{"date":482,"type":23},{"name":44,"class":45},{"id":651,"slug":652,"hasResults":12,"nctId":653,"briefTitle":654,"officialTitle":655,"acronym":4,"eligibilityCriteria":656,"healthyVolunteers":17,"sex":355,"minAge":657,"maxAge":658,"enrollmentInfo":659,"targetDuration":4,"studyType":24,"phases":661,"briefSummary":662,"conditions":663,"keywords":667,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":671,"lastUpdatePostDateStruct":672,"startDateStruct":674,"completionDateStruct":676,"leadSponsor":678,"locationsCount":4},"100560618","effects-of-competitive-exergame-on-weight-loss-mental-health-and-social-emotional-100560618","NCT06579495","Effects of Competitive Exergame on Weight Loss, Mental Health, and Social-emotional","Effects of Competitive Exergame on Weight Loss, Mental Health, and Social-emotional Among Overweight and Obese Male Adolescents in China","Inclusion Criteria:\n\n* The age of the experimental subjects should be 12-14 years old;\n* The student had never played AVG before;\n* The students' BMI percentile should be more than 85;\n* There are no other sports besides daily physical activities;\n* The students without physical and\u002For mental disabilities;\n\nExclusion Criteria:\n\n* Having self-reported physical and\u002For mental disabilities;\n* Having motion sickness reaction when exercising under AVG based condition;\n* Relevant weight loss medicine taken within half a year;","12 Years","14 Years",{"count":660,"type":23},75,[26],"Overweight and obesity are prevalent, especially among adolescents. By 2016, over 124 million children and adolescents, comprising 6% of girls and 8% of boys, were classified as obese. Over the past century, childhood obesity has transitioned from a symbol of prosperity and well-being to being acknowledged as a significant health concern. Furthermore, according to the World Health Organization, it is now considered \"one of the most serious challenges of the 21st century.\" Overweight and obese adolescents have serious problems with weight loss, mental health and social-emotional. A previous study by Lopez identified time constraints and a lack of motivation as hindrances to physical activity, a key component of effective weight loss measures.\n\nIn today's society, developed modern technology plays a very important role in the growth of teenagers and in their daily life. Exergame is a new type of video game that allows participants to be more active, stimulating their whole body movement game experience and promoting non-sedentary physical activity. Active Video Games (AVGs) utilize motion-sensing technology to simplify the complex functions typically associated with computer operations. Exergaming is a novel video game that stimulates an active whole-body gaming experience that allow to play multiple players compete or cooperate on a team. Playing against a peer offering both virtual and real social interaction is more likely to sustain engagement, and also promotes higher energy expenditure in an exergame compared to playing alone.\n\nHarnessing adolescents' fascination with video games represents an innovative strategy in the battle against pediatric obesity and sedentary lifestyles. It is especially important to intervene with overweight and obese adolescents using Competitive exergame to become more actively involved in sports, no longer afraid of social interaction, and improve quality of life. Competitive exergame provides a virtual and a real social interaction to improve mental health on overweight and obese adolescents. Therefore, the study will systematically investigate the effects of Competitive Exergame on Weight loss, Mental health,and Social-emotional among overweight and obese male adolescents in China.",[664,665,666],"Weight Loss","Mental Health Issue","Overweight and Obesity",[668,669,670],"Competitive Exergame","Mental Health","Social-emotional","2024-08-27",{"date":673,"type":38},"2024-08-30",{"date":675,"type":23},"2024-09",{"date":677,"type":23},"2024-12",{"name":44,"class":45},""]