[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universiti Tunku Abdul Rahman\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":194},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,47,74,100,121,149,168],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100632592","efficacy-and-safety-of-acupuncture-combined-with-chinese-herbal-fumigation-for-chronic-non-specific-neck-pain-100632592",false,"NCT07515690","Efficacy and Safety of Acupuncture Combined With Chinese Herbal Fumigation for Chronic Non-Specific Neck Pain","Efficacy and Safety of Acupuncture Combined With Chinese Herbal Fumigation in the Treatment of Chronic Non-Specific Neck Pain: A Multicenter Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18 to 65 years, any gender\n* Diagnosed with chronic non-specific neck pain lasting ≥ 3 months\n* Visual Analog Scale (VAS) pain score ≥ 4\n* Cervical range of motion reduced by ≥ 20% compared to normal range\n* Conformity to both Western diagnostic criteria and Traditional Chinese Medicine pattern differentiation for \"cold coagulation type\" neck pain\n* Voluntarily participate and provide signed informed consent\n\nExclusion Criteria:\n\n* Presence of confirmed cervical disc herniation, nerve compression, or other specific pathologies (e.g., infection, tumor, fracture, etc.)\n* History of cervical spine surgery or recent acute neck trauma\n* Concomitant severe systemic diseases (e.g., cardiovascular, hepatic, renal, hematological, or psychiatric disorders)\n* Pregnancy or breastfeeding\n* Known allergy to acupuncture needles or herbal fumigation components\n* Receipt of other neck pain-related treatments (e.g., physical therapy, medication, or acupuncture) within the past month\n* Presence of open wounds or skin lesions in the treatment area\n* Any patient not meeting the inclusion criteria","ALL","18 Years","65 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","Chronic non-specific neck pain is a common musculoskeletal disorder that significantly affects quality of life and functional ability. Conventional treatments often provide limited relief and may be associated with adverse effects. Acupuncture and Chinese herbal fumigation are commonly used therapies in traditional Chinese medicine and have shown potential benefits in pain relief and functional recovery.\n\nThis multicenter randomized controlled trial aims to evaluate the efficacy and safety of acupuncture combined with Chinese herbal fumigation in patients with chronic non-specific neck pain. A total of 120 participants will be randomly assigned to three groups: acupuncture combined with Chinese herbal fumigation, acupuncture combined with sham fumigation, and acupuncture alone. All participants will receive five treatment sessions within three weeks, followed by a four-week follow-up period.\n\nThe primary outcome measure is pain intensity assessed using the Visual Analog Scale (VAS). Secondary outcome measures include the Neck Disability Index (NDI), cervical range of motion, Pittsburgh Sleep Quality Index (PSQI), quality of life scale, and Central Sensitization Inventory (CSI). This study aims to provide high-quality clinical evidence regarding the effectiveness of acupuncture combined with Chinese herbal fumigation for chronic non-specific neck pain.",[27],"Chronic Non-specific Neck Pain",[29,30,31,32,33],"Acupuncture","Chinese herbal fumigation","Chronic neck pain","Traditional Chinese medicine","Randomized controlled trial","NOT_YET_RECRUITING","2026-04-07",{"date":37,"type":38},"2026-04-13","ACTUAL",{"date":40,"type":21},"2026-05",{"date":42,"type":21},"2027-03",{"name":44,"class":45},"Universiti Tunku Abdul Rahman","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":53,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":46},"100600083","effects-of-chamomile-with-l-theanine-beverage-among-young-women-experiencing-primary-dysmenorrhea-100600083","NCT07092878","Effects of Chamomile With L-theanine Beverage Among Young Women Experiencing Primary Dysmenorrhea","Inclusion Criteria:\n\n* A VAS score of ≥4 cm for the past three consecutive menstrual cycles\n* Regular monthly menstruation\n* No history of allergies or psychological\u002Fgynecological illnesses\n* Absence of secondary dysmenorrhea\n* No current use of any medications\n* No ongoing non-pharmacological management for dysmenorrhea.\n\nExclusion Criteria:\n\n* Pregnant\n* Breastfeeding","FEMALE","30 Years",{"count":56,"type":21},30,[24],"This study aims to evaluate the effects of a beverage containing chamomile and L-theanine on menstrual symptoms, pain intensity, mood, and sleep quality among young adult females with primary dysmenorrhea.",[60],"Primary Dysmenorrhea",[62,63,64],"primary dysmenorrhea","sleep","mood","RECRUITING","2025-07-21",{"date":68,"type":38},"2025-07-30",{"date":70,"type":38},"2025-03-01",{"date":72,"type":21},"2025-07-31",{"name":44,"class":45},{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":80,"targetDuration":82,"studyType":83,"phases":4,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":46},"100595903","prevalence-and-determinants-of-migraine-among-headache-patients-100595903","NCT07038499","Prevalence and Determinants of Migraine Among Headache Patients","Inclusion Criteria:\n\n• Patients diagnosed with headache according to the International Classification of Headache Disorders, 3rd Edition (ICHD-3).\n\nExclusion Criteria:\n\n* Patients with other major diseases or severe mental disorders;\n* History of endocrine, immune, or nervous system diseases or other severe somatic diseases.",{"count":81,"type":21},158,"1 Day","OBSERVATIONAL","Migraine is a prevalent and disabling neurological condition that often coexists with other health issues, such as hypertension and impaired physical, mental, and social functioning. Understanding the prevalence of migraine and its associations with these health domains can provide valuable insights into the broader impact of migraine on overall well-being. By focusing on patients at the Affiliated Hospital of Hebei University of Engineering in China, this study can identify specific health burdens within this population, inform integrated clinical management strategies, and support the development of targeted interventions to improve patient outcomes and quality of life.",[86],"Headache (Migraine)",[88,89,90,91],"Pain","Headache","Migraine","Disability","2025-06-25",{"date":94,"type":38},"2025-06-26",{"date":96,"type":21},"2025-06-23",{"date":98,"type":21},"2025-10-31",{"name":44,"class":45},{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":108,"briefSummary":109,"conditions":110,"keywords":111,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},"100594827","effectiveness-of-auricular-acupuncture-for-migraine-100594827","NCT07024511","Effectiveness of Auricular Acupuncture for Migraine","Inclusion Criteria:\n\n* Diagnosed as having migraine with aura and without aura according to the diagnostic criteria specified by the ICHD 3;\n* Aged between 18 and 65 years old;\n* Provided written informed consent;\n* Headache lasting for 4 to 72 hours and occur at least 5 times (untreated or poorly treated);\n* At least 2 out of 4 criteria must be met (unilateral, pulsatile, moderate to severe pain, headache aggravated by daily physical activity, or avoidance of daily activities such as walking or climbing stairs due to headache);\n* At least one of the two criteria must be met (nausea and\u002For vomiting, photophobia, and fear of sound);\n* At least one fully recoverable premonitory symptom (visual, sensory, speech and\u002For language, motor, brainstem, retina); Onset time more than 5 minutes; (8) No prophylaxis treatments with acupuncture or drugs in the past 3 months; (9) Written informed consent provided.\n\nExclusion Criteria:\n\n* All other diagnoses of chronic, tension-type headache, cluster headache and\u002For secondary headaches;\n* History of psychotic disorder(s).;\n* Pregnancy or lactation;\n* Severe somatic disorder(s);\n* History of severe organic psychiatric disorder(s);\n* History of other chronic pain condition(s) in the pass 3 months;\n* History of addictive disorder(s);\n* Visual Aura Rating Scale, VARS≥5 score;\n* Taking long-term painkillers for more than 1 month within 3 months.",{"count":107,"type":21},156,[24],"Migraine is a primary headache disorder characterized by recurrent episodes of moderate to severe pain, frequently accompanied by nausea, photophobia, and phonophobia. It ranks as the third most prevalent medical condition globally and is recognized by the World Health Organization (WHO) as one of the top ten causes of disability worldwide. Migraine presents substantial public health concerns due to its considerable socioeconomic burden and its detrimental impact on individuals' quality of life. Although pharmacological treatments are widely available, their effectiveness is often limited, with many patients experiencing inadequate symptom relief or adverse side effects. Consequently, there has been growing interest in non-pharmacological approaches, particularly acupuncture and auricular therapy, due to their favorable safety profiles and reported efficacy in alleviating migraine symptoms. Auricular therapy, a microsystem of acupuncture applied to specific points on the external ear, has gained popularity for its simplicity, low risk, and therapeutic potential. Despite its increasing clinical use, robust scientific evidence supporting the effectiveness of auricular therapy for migraine remains insufficient, underscoring the need for well-designed clinical studies to validate its therapeutic value.",[90],[88,90],"2025-06-12",{"date":114,"type":38},"2025-06-17",{"date":116,"type":21},"2025-07-01",{"date":118,"type":21},"2025-12-31",{"name":44,"class":45},2,{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":4,"eligibilityCriteria":127,"healthyVolunteers":11,"sex":53,"minAge":17,"maxAge":4,"enrollmentInfo":128,"targetDuration":4,"studyType":22,"phases":129,"briefSummary":130,"conditions":131,"keywords":134,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":46},"100427273","tcm-as-an-adjuvant-treatment-in-breast-cancer-patients-100427273","NCT04843865","TCM as an Adjuvant Treatment in Breast Cancer Patients","A Systemic Approach to Study the Traditional Chinese Medicine as an Adjuvant Treatment in Breast Cancer Patients","Inclusion Criteria:\n\n* Postmenopausal women as determined by cessation of menses for at least 1 year or FSH\\>20 mIU\u002FmL\n* Histology confirmed stage 2 to 3 hormone-receptor positive breast cancer patient\n* Currently taking letrozole for at least 1 month\n* Reported ongoing musculoskeletal pain or stiffness, which started or worsened after initiation of letrozole\n* Had a baseline average pain score over the past week on the Brief Pain Inventory Short Form (BPI-SF) of ≥4 points on a scale of 0 to 10.\n* Completed all indicated surgery, chemotherapy and radiation therapy\n* Agreed to take prescribed Chinese herbs\n* No evidence of distant metastasis\n* Follow-up for the duration of the study\n* No acute disease in the past month\n* Able to communicate to practitioner and interviewer\n* Willing to give informed consent\n\nExclusion Criteria:\n\n* Pregnant or nursing woman or woman of childbearing potential without effective method of birth control.\n* Patients who default subsequent follow-up\u002F has irregular follow-up.\n* Patients who directly involved in other study at the same time.\n* History of non-compliance to medical regime and patients who are unwilling or unable to comply with the protocol.\n* Bedridden and\u002F or cancer metastasis to bone\u002F lung.\n* Concurrent infection requiring intravenous antibiotics\n* History of allergy to Chinese herbs\n* Had previously received Chinese herbs for their AI-induced musculoskeletal symptoms\n* Had received Chinese herbs within one month prior to study entry\n* Current use of steroids or narcotics for pain relief within the past 2 weeks\n* Subjects with acute onset of a chronic illness or with acute disease in the past month or had pre-existing chronic diseases\n* Patients with concomitant severe illness or metastatic disease (poorly controlled hypertension, hypothyroidism, diabetes mellitus, liver diseases, osteoarthritis, rheumatoid arthritis, gout or neuropathic arthropathy, autoimmune or inflammatory joint disease, bone fracture, stroke)",{"count":56,"type":21},[24],"Chinese herbs can alleviates the side effects caused by conventional treatment in breast cancer patients and affects the syndrome element differentiation by altering the specific set of proteomes at specific time point of treatment.",[132,133],"Breast Cancer","Musculoskeletal Pain",[135,136,137,138,139,140],"Chinese herbs","Breast cancer","Aromatase inhibitor-associated musculoskeletal symptoms","Protein profiling","System biology","Syndrome element differentiation","2024-12-30",{"date":143,"type":38},"2024-12-31",{"date":145,"type":38},"2022-04-22",{"date":147,"type":21},"2024-12",{"name":44,"class":45},{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":156,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":158,"conditions":159,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":167,"locationsCount":46},"100445146","biomarkers-tcm-body-constitution-dietary-pattern-and-psychological-factors-in-predicting-depression-100445146","NCT05076643","Biomarkers, TCM Body Constitution, Dietary Pattern and Psychological Factors in Predicting Depression","Biomarkers, Traditional Chinese Medicine Body Constitution, Dietary Pattern and Psychological Factors in Predicting Depression Among University Students in UTAR, Malaysia","Inclusion Criteria:\n\n* Malaysian citizen\n* Able to read and communicate in English\n\nExclusion Criteria:\n\n* Special education disability (deaf and blind)\n* Physical support\n* History of infectious diseases",{"count":157,"type":21},397,"This study aims to determine the predictors of depression among university students in Universiti Tunku Abdul Rahman (UTAR) Sungai Long Campus.",[160],"Depression","2024-08-24",{"date":163,"type":38},"2024-08-27",{"date":165,"type":38},"2022-03-17",{"date":147,"type":21},{"name":44,"class":45},{"id":169,"slug":170,"hasResults":11,"nctId":171,"briefTitle":172,"officialTitle":173,"acronym":4,"eligibilityCriteria":174,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":175,"enrollmentInfo":176,"targetDuration":4,"studyType":22,"phases":178,"briefSummary":180,"conditions":181,"keywords":182,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":193,"locationsCount":46},"100496249","phase-3-physiotherapy-intervention-for-migraine-symptoms-100496249","NCT05741775","Physiotherapy Intervention for Migraine Symptoms","Efficacy of Physiotherapy Intervention Among University Students With Migraine Symptoms","Inclusion Criteria:\n\n* Undergraduate, and postgraduate students from Universiti Tunku Abdul Rahman\n* 4 of 5 on the Migraine Screen Questionnaire\n\nExclusion Criteria:\n\n* Score of more than or equal to 5 on the visual aura rating scale,\n* Diagnosed to have a secondary headache (headache attributed to the causative disorder example: infection, trauma, injury to head\u002F or neck)\n* Pregnancy,\n* Took medication for neurological conditions like stroke, multiple sclerosis and took medications for cardiorespiratory conditions like asthma,\n* Took medications for headache and\n* Unwilling to participate will be excluded","40 Years",{"count":177,"type":21},87,[179],"PHASE3","The goal of this randomized control trial is to analyse the effectiveness of Physiotherapy intervention among university students with migraine symptoms. The main objective is:\n\n1. To determine the effect of aerobic exercise on the resting-state brainwaves among university students in UTAR with migraine symptoms compared with biofeedback and control exercise.\n2. To analyse the influence of aerobic exercise on the sleep quality and quality of life among the cohort compared with biofeedback and control exercise.\n\nAlthough the Migraine Research Foundation listed three main types of non-drug treatments for migraine are lifestyle advice, therapies, and exercises. Some common aerobic exercises such as walking, jogging, a behavioral weight loss program, cycling, and a combination of cross-training, walking, jogging, and cycling are suggested to be beneficial to the migraine patients but there remains no specific protocol established till now. Hence the other main objective of this is to establish a aerobic exercise protocol for patients with migraine symptoms.",[90],[183,184,185,186],"Migraine symptoms","Aerobic exercise","Biofeedback training","University students","2024-06-28",{"date":189,"type":38},"2024-07-01",{"date":191,"type":38},"2022-09-18",{"date":147,"type":21},{"name":44,"class":45},""]