[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University Hospital Augsburg\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":319},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,55,80,105,137,165,193,217,245,271,294],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":35,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100643240","the-warm-study-is-a-pilot-study-that-aims-to-investigate-the-impact-of-environmental-factors-on-acute-and-chronic-wounds-mental-illness-and-social-factors-among-people-experiencing-housing-emergencies-in-augsburg-100643240",false,"NCT07640672","The WARM Study is a Pilot Study That Aims to Investigate the Impact of Environmental Factors on Acute and Chronic Wounds, Mental Illness, and Social Factors Among People Experiencing Housing Emergencies in Augsburg.","Impact of Environmental Factors on Acute and Chronic Wounds, Mental Illness, and Social Factors Among People Experiencing Housing Emergencies in Augsburg","WARM","Inclusion Criteria:\n\n* Age over 18\n* Existing capacity to consent to participation in the study, which will be verified and documented by the study physicians\n* Inclusion of patients who present for wound treatment at the Johanniter-Hilfsmobil, the wound consultation hour of the Clinic for Vascular Surgery at Augsburg University Hospital and\u002For the substitution outpatient clinic of the Clinic for Psychiatry, Psychotherapy and Psychosomatics at Augsburg District Hospital\n* Written consent to participate in the study has been obtained from the test subject.\n\nExclusion Criteria:\n\n* Minderjährigkeit\n* Fehlende schriftliche Einwilligung zur Studienteilnahme\n* Instabiler somatischer Zustand der Betroffenen\n* Akute Selbst- und Fremdgefährdung","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","Providing healthcare to homeless people is a key and challenging task, both for society as a whole and for medical and psychosocial professionals. It must be noted that the standard healthcare system is hardly used, or can only be used to an insufficient extent, by homeless people, and therefore does not comprehensively reach this group. One low-threshold and acceptance-oriented service outside the standard care system is the Johanniter-Hilfsmobil, which was established on June 3, 2024, as an innovative approach to healthcare for homeless people in Augsburg and will be scientifically examined in the following study.\n\nThe aim is to compare acute and chronic wounds in people experiencing housing emergencies who are treated by the Johanniter-Hilfsmobil with those of patients who attend the outpatient wound clinic at the Clinic for Vascular Surgery at Augsburg University Hospital.\n\nIn addition, a saliva test will be carried out to estimate the amount and type of substance consumed, and a survey will be conducted among drug-dependent test subjects who present themselves either via the Johanniter-Hilfsmobil or via the substitution outpatient clinic of the Clinic for Psychiatry, Psychotherapy, and Psychosomatics at Augsburg District Hospital.\n\nAnother focus of research is the quantitative and qualitative analysis of the psychosocial living situation and environmental influences on users of the Johanniter-Hilfsmobil.",[27,28,29,30,31,32,33,34],"Homeless Persons","Wound and Injuries","Chronic Wound Care","Homelessness","Environmental Health","Environmental Factors","Psychiatric Disorders","Drug Abuse\u002FDependence",[36,37,38,39,40,41],"wound care","environmental health","wound and injuries","homeless persons","psychiatric disorders","drug abuse\u002Fdependence","NOT_YET_RECRUITING","2026-06-05",{"date":45,"type":46},"2026-06-11","ACTUAL",{"date":48,"type":21},"2026-06-01",{"date":50,"type":21},"2027-12-31",{"name":52,"class":53},"University Hospital Augsburg","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":22,"phases":66,"briefSummary":67,"conditions":68,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":54},"100637697","subcutaneous-suture-versus-no-subcutaneous-suture-for-abdominal-wound-closure-100637697","NCT07615517","Subcutaneous Suture Versus no Subcutaneous Suture for Abdominal Wound Closure","Subcutaneous Suture Versus no Subcutaneous Suture for Abdominal Wound Closure in Abdominal Surgery","SUTURE","Inclusion Criteria:\n\n* Adult patients (≥18 years)\n* elective laparotomy (midline laparotomy, transverse laparotomy, subcostal incision, thoracoabdominal incision, or extended Pfannenstiel incision) or laparoscopically assisted abdominal surgery with a specimen extraction incision of at least 6 cm.\n\nExclusion Criteria:\n\n* Emergency laparotomy.\n* Anticipated or documented non-compliance with study procedures or follow-up.\n* Patients in whom primary wound closure cannot be achieved at the end of surgery.\n* Patients unable to provide informed consent.",true,{"count":65,"type":21},655,[24],"Surgical site infections are among the most frequent complications after abdominal surgery and are associated with impaired wound healing, prolonged hospital stay, additional treatments, and increased healthcare costs. Closure of the subcutaneous tissue before skin closure is commonly performed in abdominal surgery, but the available evidence supporting this practice remains limited and heterogeneous, particularly outside caesarean section surgery.\n\nThe SUTURE trial is a prospective, randomized, patient- and assessor-blinded superiority trial evaluating whether subcutaneous tissue closure reduces the incidence of surgical site infections after abdominal surgery. Adult patients undergoing elective open or laparoscopically\u002Frobotically assisted abdominal surgery with an abdominal incision of at least 6 cm will be randomized intraoperatively after fascial closure to either subcutaneous tissue closure using interrupted Vicryl® 2-0 sutures or no subcutaneous tissue closure. The primary endpoint is the occurrence of surgical site infection according to CDC criteria grade I-II within 30 days after surgery.\n\nThe trial aims to provide high-quality evidence on whether routine subcutaneous tissue closure should be recommended as a standardized wound closure strategy in abdominal surgery.",[69,70],"Surgical Site Infection (SSI)","Wound Healing Complication","RECRUITING","2026-05-22",{"date":74,"type":46},"2026-05-29",{"date":76,"type":46},"2026-03-23",{"date":78,"type":21},"2028-05-30",{"name":52,"class":53},{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":63,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":90,"phases":4,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":104,"locationsCount":54},"100548077","widening-aims-and-giving-patients-a-voice-for-expanded-structures-in-breast-cancer-care-jointly-developed-by-patients-and-physicians-100548077","NCT06416293","Widening Aims and Giving Patients a Voice for Expanded Structures in Breast Cancer Care Jointly Developed by Patients and Physicians","Widening Aims and Giving Patients a Voice for Expanded Structures in Breast Cancer Care Jointly Developed by Patients and Physicians (Wechselseitiger Patienten-Arzt-Austausch in Der Versorgung Bei Brustkrebs Mit Dem Ziel Der Gemeinsamen Erarbeitung Neuer Patienten-orientierter Strukturen)","WAVES","Inclusion Criteria (patients):\n\n* Breast cancer or DCIS\n* women and men aged 18 years and older\n\nExclusion Criteria (patients):\n\n* women and men \\\u003C 18 years\n* no histologically confirmed breast cancer or DCIS diagnosis\n\nInclusion Criteria (physicians):\n\n\\- Treatment of breast cancer patients",{"count":89,"type":21},2000,"OBSERVATIONAL","The aim of this BZKF project is to record the current care structure for breast cancer patients in order to use this as a basis for developing possible future models for improvement. The active involvement of representatives of regional and national patient organizations in the creation of a patient-based and patient-oriented survey ensures that the needs of patients are the focus. In addition to and in contrast to other projects, relevant questions are explicitly addressed not only to patients but also to physicians in order to identify and specify the interfaces between patient wishes\u002Fsuggestions and to develop clinical consequences for care.\n\nThe first objective is to survey the \"current situation\" by recording the current care structure for breast cancer. The focus is on the survey of both groups on patient-physician communication, time management and coping strategies.\n\nBy planning the future harmonization of national data structures, the basis is created for the long-term goal of an improved \"target\", a concept developed jointly by physicians and patients for an improved communication and care structure that focuses on the patient.",[93],"Breast Cancer",[95,96,97],"Communication","patient-physician-relationship","questionnaire","2026-04-28",{"date":100,"type":46},"2026-04-29",{"date":102,"type":46},"2022-04-01",{"date":50,"type":21},{"name":52,"class":53},{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":22,"phases":114,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":135,"locationsCount":136},"100630075","bcc-one-stop-study-100630075","NCT07482956","BCC-One-Stop-Study","Multicentre, Interventional Prospective Study to Evaluate the Efficiency of Pre- and Postoperative Margin Determination of Basal Cell Carcinomas Using Optical Coherence Tomography and Line-field Confocal Optical Coherence Tomography During Micrographically Controlled Surgery","Inclusion Criteria:\n\n* Adults (≥18 years) with basal cell carcinoma (BCC) scheduled for Mohs micrographic surgery (MMS),\n* Diagnosis confirmed by dermoscopy and histopathology or optical coherence tomography (OCT),\n* No limitation regarding tumor size or BCC subgroups.\n\nExclusion Criteria:\n\n* Poor LC-OCT image quality,\n* Incomplete adherence to the study protocol,\n* Previous treatment of the BCC,\n* Anatomical sites that are difficult to access with LC-OCT (e.g., inner ear, medial canthus of the eye).",{"count":113,"type":21},290,[24],"Basal cell carcinoma (BCC) is the most common malignant skin tumour. The standard treatment is micrographically controlled surgery (MMS), which achieves high cure rates but requires considerable time and personnel. A key problem is the inadequate preoperative determination of tumour margins, which often leads to multiple cycles of excision.\n\nThe aim of this multicentre, prospective, randomised controlled intervention study is to evaluate line-field confocal optical coherence tomography (LC-OCT) for preoperative margin determination in BCC within the framework of MMS.\n\nResearch question:\n\nCan preoperative LC-OCT-assisted margin marking increase the efficiency of MMS by reducing the number of excision cycles required without compromising oncological safety?\n\nMethodology:\n\nApproximately 290 patients with histologically confirmed BCC will be enrolled at five German centres and randomly assigned to either standard MMS or MMS with upstream LC-OCT margin determination. In the intervention group, the excision margin will be specifically extended if a tumour is detected in the LC-OCT.\n\nPrimary endpoint:\n\nNumber of MMS cycles required to achieve R0 resection.\n\nSecondary endpoints:\n\nTotal duration of surgery, size of surgical defect, cosmetic outcome (POSAS), patient satisfaction and stress, sensitivity and specificity of LC-OCT compared to histopathology.\n\nSignificance:\n\nThe study addresses the clinical conflict of objectives between complete tumour removal and maximum tissue preservation. Successful implementation could optimise MMS through modern imaging, conserve surgical resources and improve patient care in the long term.",[117],"Basal Cell Carcinoma",[119,120,121,122,123,124,125,126,127,128],"basal cell carcinoma","line-field confocal optical coherence tomography","BCC","LC-OCT","Mohs micrographic surgery","MMS","margin mapping","margin assessment","skin cancer","one stop shop","2026-03-16",{"date":131,"type":46},"2026-03-19",{"date":133,"type":21},"2026-04-01",{"date":50,"type":21},{"name":52,"class":53},5,{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":4,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":144,"targetDuration":4,"studyType":22,"phases":146,"briefSummary":147,"conditions":148,"keywords":153,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":54},"100590313","study-on-sex-specific-individualized-dose-calculation-of-contrast-agent-in-ct-examinations-100590313","NCT06965790","Study on Sex-specific, Individualized Dose Calculation of Contrast Agent in CT Examinations","Randomized Controlled Study on Sex-specific, Individualized Dose Calculation of Intravenously Administered Contrast Agent in CT Examinations in Portal Venous Phase to Achieve Equivalent Contrast in Men and Women","Inclusion Criteria:\n\n* Presence of a justifying indication for a CT scan of the thorax and abdomen with application of intravenous contrast medium and a start delay corresponding to the portal venous contrast medium phase\n* Ability to give informed consent, as well as written and verbal consent to participate in the study available\n\nExclusion Criteria:\n\n* Cardiorespiratory instability (as assessed by the attending physician)\n* Age \\\u003C18 years\n* Existing or suspected pregnancy\n* Known post hepatectomy and\u002For splenectomy\n* Lack of current height (in the same inpatient\u002Foutpatient hospital stay) or lack of possibility of height measurement\n* Lack of current daily body weight or inability to measure body weight\n* Height under 140 cm or over 220 cm\n* Body weight under 50 kg or over 120 kg\n* Contraindication to iodine-containing contrast medium (Allergy to contrast media containing iodine, Severe renal insufficiency (eGFR \\\u003C 30 ml\u002Fmin), Hyperthyroidism)",{"count":145,"type":21},400,[24],"A large proportion of radiological CT examinations require the intravenous administration of iodine-containing X-ray contrast medium. According to current guidelines, the amount required for CT examinations in the (portal) venous phase is calculated on the basis of body weight (e.g. 0.2-0.4 g iodine\u002Fkg body weight), but a standardized application dose of the contrast agent is often also used.\n\nIn earlier studies, the investigators found that the iodine contrast in vessels and organs achieved with a standardized amount of contrast agent differs significantly between women and men. On average, women showed around 10% higher iodine contrast than men of the same height and weight. The investigators attribute these differences to physiological, sex-specific differences in blood volume. For example, the blood volume of a woman 175 cm tall and weighing 75 kg is approx. 400 ml less than that of a man of the same height and weight (approx. 4.6 vs. 5.0 l, calculated according to Nadler). Taking blood volume into account, sex was no longer a significant influencing factor in a retrospective cohort (n=274).\n\nThe investigators would now like to investigate these results in a prospective study. For this purpose, two groups of patients with a clinical indication for a contrast-enhanced CT scan in the venous phase will be compared:\n\n1. control group with regular weight-adjusted (n = 200)\n2. study group with dosing according to blood volume (n = 200).\n\nThe hypothesis is that the application scheme adapted to the blood volume leads to a more homogeneous contrasting of women and men. In order to quantify this effect, the iodine contrast values of both groups will be quantitatively analyzed, taking into account other influencing variables (height, weight).\n\nThe investigators hope that this approach will reduce or even eliminate the observed sex-specific differences. This would lead to a sex-equal contrast based on an individualized amount of contrast medium.",[149,150,151,152],"CT Scans","Contrast Media","Gender","Womens Health",[154,149,150,155,156],"CT","contrast","gender","2025-12-07",{"date":159,"type":46},"2025-12-09",{"date":161,"type":46},"2025-04-01",{"date":163,"type":21},"2027-03",{"name":52,"class":53},{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":171,"eligibilityCriteria":172,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":173,"targetDuration":4,"studyType":22,"phases":174,"briefSummary":175,"conditions":176,"keywords":179,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":192},"100582948","towards-a-more-standardized-bicuspid-aortic-valve-repair-rationale-and-design-of-contour-trial---a-randomized-trial-100582948","NCT06869954","Towards a More Standardized Bicuspid Aortic Valve Repair: Rationale and Design of CONTOUR Trial - a Randomized Trial","Towards a More Standardized Bicuspid Aortic Valve Repair: Rationale and Design of CONTOUR Trial","CONTOUR","Inclusion Criteria:\n\n1. Presence of fused BAV phenotype with an asymmetric configuration (commissural orientation \\\u003C 170 degree) \\[14\\]\n2. Severe aortic regurgitation (vena contracta (vc) \\> 6mm and\u002For pressure half-time (PHT) \\\u003C 200 ms and\u002For effective regurgitant orifice area (EROA) \\> 30 mm2 and\u002For regurgitant volume (RV) \\> 60 ml\u002Fbeat and\u002For left ventricular end-systolic diameter (LVESD) \\> 50mm (or indexed LVESD \\> 20mm\u002Fm2 BSA) and\u002For regurgitation fraction (RF) in cardiothoracic MRI \\> 40%) (at least one parameter is required) \\[15\\]\n3. Isolated aortic valve surgery or concomitant procedure (including CABG and\u002For mitral\u002Ftricuspid valve surgery and\u002For ascending aortic surgery)\n4. Willingness to participate and written informed consent\n5. Age at surgery \\> 18 years\n\nExclusion Criteria:\n\n1. Moderate\u002Fsevere BAV stenosis (pmean \\> 20mmHg)\n2. Moderate\u002Fsevere BAV cusp calcifications extending beyond the raphe region and\u002For necessitating patch implantation (deemed irreparable based on preoperative TOE (as by decision of the operating surgeon)\n3. Concomitant aortic root aneurysm \\> 45mm requiring simultaneous aortic root surgery \\[16\\]\n4. Acute\u002Fsubacute BAV endocarditis\n5. Contraindication to MRI",{"count":20,"type":21},[24],"Background: Between one-third and one-half of patients with bicuspid aortic valve (BAV) disease develop significant aortic regurgitation (AR) at a young age, leading to cardiomyopathy and heart failure. Aortic valve repair is an evolving and still underused strategy in BAV patients with AR. The lack of sufficient standardization remains the main limitation of current repair techniques, resulting in an increased risk of AR recurrence and reoperation. The most controversial issue is the stabilization of the BAV annulus. The CONTOUR trial aims to compare two different BAV annuloplasty concepts in a prospective randomized study.\n\nMethods: CONTOUR is a multicenter, randomized controlled trial designed to enroll 100 consecutive BAV patients with AR across four sites in Germany. BAV AR patients with an asymmetric configuration and without concomitant root aneurysm will be randomized 1:1 to undergo aortic valve repair using an internal HAART 200 annuloplasty device (i.e., INTERNAL group) (n=50) or external annuloplasty (i.e., double external ring annuloplasty) in the EXTERNAL group (n=50). 4D flow MRI will be performed preoperatively (t1), postoperatively at discharge (t2), and at 1-year follow-up (t3) for rater-blinded assessment of hemodynamic profiles (i.e., flow eccentricity) and regurgitation fraction at the MRI core-lab. Two hierarchically ordered primary endpoints will be considered: (1) postoperative reduction of flow eccentricity at hospital discharge and (2) regurgitation fraction (%) at 1-year follow-up.\n\nDiscussion: The CONTOUR trial is designed to test the hypothesis that an internal annuloplasty device, creating a completely symmetric post-repair BAV geometry, achieves superior aortic valve repair outcomes compared to external annuloplasty. If our hypothesis is confirmed, our study will significantly influence aortic valve repair practice and contribute to the refinement of guideline recommendations in the management of BAV patients with AR.",[177,178],"Bicuspid Aortic Valve (BAV)","Aortic Regurgitation Disease",[180,181,182,183],"aortic regurgitation","aortic valve repair","annuloplasty","bicuspid aortic valve","2025-10-01",{"date":186,"type":46},"2025-10-07",{"date":188,"type":46},"2025-05-21",{"date":190,"type":21},"2027-06",{"name":52,"class":53},4,{"id":194,"slug":195,"hasResults":11,"nctId":196,"briefTitle":197,"officialTitle":198,"acronym":199,"eligibilityCriteria":200,"healthyVolunteers":63,"sex":201,"minAge":18,"maxAge":4,"enrollmentInfo":202,"targetDuration":4,"studyType":22,"phases":203,"briefSummary":204,"conditions":205,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":209,"lastUpdatePostDateStruct":210,"startDateStruct":212,"completionDateStruct":214,"leadSponsor":216,"locationsCount":54},"100508359","seroma-of-the-mammary-gland-100508359","NCT05899387","Seroma of the Mammary Gland","Prospective, International, Multicenter Minimal Interventional Study to Detect Possible Markers for Prediction of Seroma Development and Risk Assessment of a Breast Seroma After Mastectomy with or Without Implant-based Breast Reconstruction","SerMa","Inclusion criteria study group and control group 1:\n\n* Written informed consent\n* Age ≥ 18 years\n* all stages of DCIS or primary breast cancer (T1-T4, N0 or N+, M0) including all histopathological subtypes (ER\u002FPR positive, ER positive\u002FPR negative, Her-2\u002Fneu positive and triple negative)\n* Surgical procedure planned including ablatio or subcutaneous mastectomy with implant or expander insertion\n\nInclusion criteria control group 2 and 3:\n\n* Written informed consent\n* Age ≥ 18 years\n* Surgical procedure planned with implant or expander insertion with or without subcutaneous mastectomy\n\nExclusion criteria:\n\n* Age \\\u003C18 years\n* Male sex\n* Breast cancer patients planned for breast conserving therapy\n* Recurrent breast cancer disease\n* History of breast surgery\n* Diagnosis of LCIS only\n* Pregnancy at time of diagnosis\n* Patients with a known immunodeficiency","FEMALE",{"count":89,"type":21},[24],"The study is designed as international, prospective, minimal interventional study in cooperation with EUBREAST e.V. (European Breast Cancer Research Association of Surgical Trialists). Furthermore, it is planned to initiate a registry for postoperative breast seromas.",[206,93,207,208],"Seroma","Mastectomy","Breast Implant; Complications","2025-02-25",{"date":211,"type":46},"2025-02-28",{"date":213,"type":46},"2024-04-01",{"date":215,"type":21},"2027-07-01",{"name":52,"class":53},{"id":218,"slug":219,"hasResults":11,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":223,"eligibilityCriteria":224,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":225,"targetDuration":4,"studyType":22,"phases":226,"briefSummary":227,"conditions":228,"keywords":232,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":54},"100570206","stress-reduction-using-video-googles-on-patients-undergoing-vascular-surgery-100570206","NCT06704230","Stress Reduction Using Video Googles on Patients Undergoing Vascular Surgery","Multimedia Patient Entertainment During Vascular Surgery Procedures in Regional Anesthesia","MEP-VASC","Inclusion Criteria:\n\n* Planed carotid endarterectomy in local anesthesia\n\nExclusion Criteria:\n\n* patients which are not able to communicate because of stroke or language barrier,\n* Dementia or neurological damage which impairs answering questionnaires or the understanding of the situation during surgery\n* medication with steroids",{"count":20,"type":21},[24],"One treatment option of internal carotid artery stenosis is open surgical endarterectomy. The operation is frequently carried out under regional plexus anesthesia, allowing the patient to remain awake during the procedure. This approach offers the advantage of monitoring for neurological changes during carotid artery clamping, allowing the surgical team to immediately respond by placing a shunt to ensure cerebral perfusion. As a result, performing surgery under regional anesthesia provides therefor a benefit. However, for patients, the procedure, which can last up to two hours or longer in some cases, may pose a significant burden. The fixed position, inability to move, sterile drapes over the face, manipulation by the surgical team, and anxiety about potential complications are just a few of the factors that may distress patients during the operation. Increased sweating and reports of substantial subjective distress are not uncommon if the procedure is performed under local anesthesia.\n\nIn many medical fields, devices and therapies are now being utilized to reduce patient stress in the perioperative setting. In procedures performed under local or regional anesthesia, such as in orthopedics or dentistry, efforts are being made to make operations more tolerable and less stressful for patients. For example, music and video goggles are employed to entertain and distract patients during the intervention. Newer approaches using video googles appear in more and more fields to reduce distress. Especially in vascular surgery and particularly in carotid surgery, the use of audiovisual distraction during the procedure has not been implemented to our knowledge, and its benefits remain undocumented. Because of the special setting and burden for the patients it is highly necessary to test these devices in carotid surgery and explore potential benefits for these patients.",[229,230,231],"Carotid Artery Diseases","Regional Anesthesia","Distress, Procedural",[233,234,235,236],"video googles","carotid endarterectomy","distress in patients","vascular surgery","2024-11-22",{"date":239,"type":46},"2024-11-26",{"date":241,"type":46},"2022-09-09",{"date":243,"type":21},"2025-04",{"name":52,"class":53},{"id":246,"slug":247,"hasResults":11,"nctId":248,"briefTitle":249,"officialTitle":249,"acronym":4,"eligibilityCriteria":250,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":251,"targetDuration":4,"studyType":90,"phases":4,"briefSummary":253,"conditions":254,"keywords":256,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":263,"lastUpdatePostDateStruct":264,"startDateStruct":266,"completionDateStruct":268,"leadSponsor":270,"locationsCount":54},"100544150","analysis-of-individual-activity-at-the-time-of-aortic-rupture-in-patients-with-abdominal-aortic-aneurysms-100544150","NCT06365138","Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms","Inclusion Criteria:\n\n* inclusion of all patients with ruptured aortic aneurysm in Augsburg University Hospital\n* Written consent to participate in the study by the patient or their legal representative\n\nExclusion Criteria:\n\n* Lack of consent",{"count":252,"type":21},500,"It is currently unclear what activities aneurysms are involved in at the time of rupture. The aim of the study is to determine the activity performed at the time of aneurysm rupture.",[255],"Aortic Aneurysm",[257,258,259,260,261,262],"Aortic Rupture","Physical stress","Emotional Stress","Rupture Risc","Follow-Up","Activity","2024-04-11",{"date":265,"type":46},"2024-04-15",{"date":267,"type":46},"2024-01-01",{"date":269,"type":21},"2030-12-01",{"name":52,"class":53},{"id":272,"slug":273,"hasResults":11,"nctId":274,"briefTitle":275,"officialTitle":276,"acronym":4,"eligibilityCriteria":277,"healthyVolunteers":63,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":278,"targetDuration":279,"studyType":90,"phases":4,"briefSummary":280,"conditions":281,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":286,"lastUpdatePostDateStruct":287,"startDateStruct":289,"completionDateStruct":291,"leadSponsor":293,"locationsCount":54},"100538712","intraocular-lens-implant-registry-study-100538712","NCT06294405","Intraocular Lens Implant Registry Study","Development of a Database to Optimize the Results With Intraocular Lens Implants","Inclusion Criteria:\n\nTreatment with an intraocular lens implant 18 years of age or older Patient consent Full legal capacity\n\nExclusion Criteria:\n\nDementia Pregnancy Breastfeeding",{"count":252,"type":21},"6 Months","The goal of this registry study is to optimize the results with intraocular lens implants used in cataract surgery.",[282,283,284,285],"Intraocular Lens Complication","Intraocular Lens Rotation","Intraocular Lens Associated Postoperative Inflammation","Lens Opacities","2024-03-04",{"date":288,"type":46},"2024-03-05",{"date":290,"type":46},"2024-02-21",{"date":292,"type":21},"2029-02-14",{"name":52,"class":53},{"id":295,"slug":296,"hasResults":11,"nctId":297,"briefTitle":298,"officialTitle":298,"acronym":4,"eligibilityCriteria":299,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":300,"targetDuration":4,"studyType":90,"phases":4,"briefSummary":302,"conditions":303,"keywords":305,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":311,"lastUpdatePostDateStruct":312,"startDateStruct":314,"completionDateStruct":316,"leadSponsor":318,"locationsCount":54},"100504285","registry-for-vascular-trauma-and-follow-up-examinations-100504285","NCT05846321","Registry for Vascular Trauma and Follow-up Examinations","Inclusion Criteria:\n\n* Age over 18 years\n* Vascular involvement in trauma\n* Isolated vascular injury\n* Written informed consent, except for those deceased from trauma sequelae\n\nExclusion Criteria:\n\n* Minority\n* Lack of consent",{"count":301,"type":21},300,"Within the framework of the project presented here, a registry for traumatic vascular injuries will be established at Augsburg University Hospital. Patients who are treated at our hospital for an isolated vascular trauma or a vascular involvement in (poly-)trauma will be included. This is a rare complication of trauma, so data collection in a registry is useful to pool data on therapeutic procedures and outcome.\n\nThese patients differ from the usual vascular surgery patient clientele because there is usually no previous vascular disease. Healthy vessels show different physiological responses than pre-diseased vessels. The usual therapeutic procedures and materials are also developed for arteriosclerotic or aneurysmatic vessels. Therefore, a core objective of this study is to assess long-term outcomes after vascular trauma.",[304],"Vascular Injury",[306,307,308,309,310],"Trauma","Vascular trauma","Bleeding","Ischemia","Registry","2023-09-07",{"date":313,"type":46},"2023-09-13",{"date":315,"type":46},"2023-06-01",{"date":317,"type":21},"2030-12-31",{"name":52,"class":53},""]