[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University Hospital of Ferrara\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":518},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,18,0,[8,43,67,89,113,139,165,193,220,243,272,296,322,349,372,403,436,491],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100637150","transcatheter-aortic-valve-implantation-without-on-site-cardiac-surgery-100637150",false,"NCT07604402","TRanscatheter Aortic-Valve Implantation Without On-site Cardiac Surgery","TRanscatheter Aortic-Valve Implantation Without On-site Cardiac Surgery Broadened Access","TRACS-PRIME","Inclusion criteria\n\n1. Severe aortic stenosis\n2. Indication to TAVI confirmed by the Heart Team\n\nAND one of the following enrichment criteria:\n\n1. Prohibitive operative risk\n2. High surgical risk as defined as STS score \\>8%\n3. Porcelain aorta or severely atherosclerotic aorta\n4. Frailty\u002FReduced physical performance\n5. Severe liver disease\u002Fcirrhosis\n6. Hostile chest and\u002For internal mammalian artery or other critical conduit(s) crossing midline and\u002For adhering to the posterior table of the sternum\n7. Severe pulmonary hypertension and\u002For severe right ventricular dysfunction\n8. Age ≥85 years\n9. Severe Chronic Obstructive Pulmonary Disease (COPD) The criteria listed above qualify the patient for eligibility in the study if present immediately after the heart team has indicated TAVI. However, this does not exclude patients without these criteria from entering the study if the heart team's evaluation still considers their risk\u002Fbenefit profile appropriate for inclusion in the protocol.\n\nExclusion criteria\n\n1. Unsuitable for transfemoral TAVI\n2. Emergent TAVI\n3. Non-cardiovascular comorbidity reducing life expectancy to \\\u003C1 year\n4. Any factor precluding 1-year follow-up\n5. Refusal of informed consent","ALL",{"count":19,"type":20},1612,"ESTIMATED","INTERVENTIONAL",[23],"NA","TRACS-PRIME is a prospective, randomized, multicenter clinical trial evaluating whether transcatheter aortic valve implantation (TAVI) can be performed safely and effectively in selected hospitals without on-site cardiac surgery, when appropriate patient selection, experienced operators, advanced imaging, and established transfer pathways are available. The study will include patients with severe symptomatic aortic stenosis who have an indication for TAVI confirmed by a multidisciplinary Heart Team. Eligible patients will be randomized to undergo TAVI either in a center without on-site cardiac surgery or in a center with on-site cardiac surgery. All procedures will be performed according to current standards of care by experienced TAVI operators. The main purpose of the study is to determine whether TAVI performed in centers without on-site cardiac surgery is not inferior to TAVI performed in centers with on-site cardiac surgery with respect to clinical outcomes at 1 year. The primary clinical outcome includes death from any cause, stroke, or hospitalization related to the procedure or the implanted valve. The study will also assess safety outcomes, including valve-related death and major procedural or technical complications. Participants will be followed after hospital discharge to assess clinical events, safety, and longer-term outcomes. An independent committee blinded to treatment allocation will review clinical events, and an independent Data Safety Monitoring Board will monitor patient safety during the trial.",[26],"Aortic Stenosis",[28,29],"TAVI","on-site cardiac surgery","RECRUITING","2026-05-26",{"date":33,"type":34},"2026-05-29","ACTUAL",{"date":36,"type":34},"2026-05-25",{"date":38,"type":20},"2034-05-25",{"name":40,"class":41},"University Hospital of Ferrara","OTHER",3,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":66},"100481331","clinical-and-diagnostic-features-of-endocarditis-100481331","NCT05547607","Clinical and Diagnostic Features of Endocarditis","Observational Prospective Multicenter Study to Characterize the cLinical ANd DiagnoStiC feAtures of Endocarditis in the contemPorary Era","ENDO-LANDSCAPE","Inclusion Criteria:\n\n* Patients above the age of 18 years.\n* all consecutive patients referred for echocardiography (transthoracic or transesophageal approach) to exclude endocarditis.\n* patients with a diagnosis of endocarditis on echocardiography independently by the request for the exam.\n\nExclusion Criteria:\n\n* patient's refusal.","18 Years",{"count":53,"type":20},500,"OBSERVATIONAL","The burden of endocarditis has changed in the last years due to an increase in percutaneous valve procedures offered to a more fragile, and old population. Therefore an update in epidemiology data is necessary. The Observational prospective multicenter study to characterize the cLinical ANd DiagnoStiC feAtures of endocarditis in the contemPorary Era, (ENDO-LANDSCAPE study) is an observational, multicenter and international study. The study has two arms: retrospective and prospective.\n\nThe retrospective arm will involve collecting data from patients discharged with a diagnosis of endocarditis between 2016 and 2022. The data obtained in the retrospective arm of the study will be utilized in a power calculation to determine the sample size for the prospective arm of the study. In the prospective phase in every participating center, all patients referred for echocardiography to assess for endocarditis and those with established endocarditis independent of the screened request will be eligible. Patients will then be stratified according to the presence or abscence of endocarditis. Those with an established diagnosis of endocarditis will be prospectively followed for outcomes.",[57],"Endocarditis","2026-04-27",{"date":60,"type":34},"2026-05-01",{"date":62,"type":34},"2022-09-09",{"date":64,"type":20},"2028-06-30",{"name":40,"class":41},1,{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":76,"targetDuration":78,"studyType":54,"phases":4,"briefSummary":79,"conditions":80,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":82,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},"100310944","scaffold-in-emilia-romagna-and-in-the-magic-network-100310944","NCT03327961","Scaffold in Emilia Romagna and in the MAGIC Network","Scaffold Implantation in Emilia-Romagna Plus Multi Absorbable Gears Intra Coronary","SHERPA-MAGIC","Inclusion Criteria:\n\n* subjects \\>18 years\n* sign of the patients informed consent\n* implanation of at least one scaffold\n\nExclusion Criteria:\n\n* inability to garantuee at least one year follow-up\n* inabiliuty to garantuee at least one year compliance to dual antiplatelet regimen",true,{"count":77,"type":20},1111,"5 Years","The prospective study will investigate the clinical performance and long-term safety of scaffold implantation in a real world regional setting. The protocol includes two different networks. The first network includes all cath-labs in the Emilia-Romagna region (SHERPA). The second includes the centers partecipating into the MAGIC retrospective study. Both networks joined into the prospective SHERPA-MAGIC project. Investigators from both networks agreed in indications and strategy implanatation described by the protocol. In each center, after IRB approval, the patients will be enrolled according to established criteria.",[81],"Coronary Artery Disease",{"date":60,"type":34},{"date":84,"type":34},"2017-12-02",{"date":86,"type":20},"2034-12-31",{"name":40,"class":41},17,{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":97,"conditions":98,"keywords":101,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":66},"100478358","atrial-fibrillation-in-beta-thalassemia-100478358","NCT05508932","Atrial Fibrillation in Beta-Thalassemia","Inclusion Criteria:\n\n1. Transfusion-dependent Beta-thalassemia;\n2. Follow-Up at the Cardiology Unit of the University Hospital of Ferrara;\n3. Electrocardiogram performed;\n4. Echocardiogram performed.\n\nExclusion Criteria:\n\n1. Age \\\u003C18 years;\n2. State Of pregnancy;\n3. Inability to give informed consent.",{"count":96,"type":20},350,"The study aims to evaluate the clinical, laboratory and instrumental differences that exist between beta-thalassemia patients with atrial fibrillation and those not affected by arrhythmia.",[99,100],"Atrial Fibrillation","Thalassemia",[99,100,102,103,104],"Thalassaemia","Arrhythmia","Hemoglobinopathies","2026-02-21",{"date":107,"type":34},"2026-02-24",{"date":109,"type":34},"2022-09-01",{"date":111,"type":20},"2032-07-01",{"name":40,"class":41},{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":119,"eligibilityCriteria":120,"healthyVolunteers":11,"sex":121,"minAge":122,"maxAge":4,"enrollmentInfo":123,"targetDuration":4,"studyType":21,"phases":125,"briefSummary":126,"conditions":127,"keywords":4,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":66},"100611744","effects-of-physical-exercise-and-cognitive-training-on-quality-of-life-in-older-women-100611744","NCT07244562","Effects of Physical Exercise and Cognitive Training on Quality of Life in Older Women","Effects of Cognitive Training and Exercise on Cognitive Function in Older Women: the INCOGNITO Randomized Clinical Trial","INCOGNITO","Inclusion Criteria:\n\n* Female\n* Age ≥ 60 years\n* Provision of the informed consent form\n\nExclusion Criteria:\n\n* Absolute contraindications to physical exercise (e.g. Nyha class iv heart failure, unstable angina, etc.)\n* Pregnancy\n* Severe cognitive impairment, defined as a MoCa score ≤ 12\n* Severe visual impairment or blindness","FEMALE","60 Years",{"count":124,"type":20},124,[23],"Ageing exposes people to a progressive loss of cognitive and functional abilities, especially in women. The aim of the study is to investigate the effectiveness of different types of intervention, based on physical exercise and\u002For cognitive stimulation or training, on quality of life, cognition and mobility, on a population of older women.",[128,129],"Elderly","Older Adults, Aging Brain","NOT_YET_RECRUITING","2025-12-04",{"date":133,"type":34},"2025-12-12",{"date":135,"type":20},"2025-12-01",{"date":137,"type":20},"2028-12-31",{"name":40,"class":41},{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":145,"eligibilityCriteria":146,"healthyVolunteers":11,"sex":17,"minAge":147,"maxAge":4,"enrollmentInfo":148,"targetDuration":4,"studyType":21,"phases":150,"briefSummary":151,"conditions":152,"keywords":154,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":159,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":66},"100611742","effects-of-physical-exercise-and-cognitive-training-on-quality-of-life-in-elderly-adults-100611742","NCT07244536","Effects of Physical Exercise and Cognitive Training on Quality of Life in Elderly Adults","Health-related Quality of Life in Elderly Adults Following Physical Exercise and Cognitive Training: a Randomized-controlled Trial","HELIOS","Inclusion Criteria:\n\n* Male and female\n* Age ≥ 70 years\n* Provision of the informed consent form\n\nExclusion Criteria:\n\n* Absolute contraindications to physical exercise (e.g. NYHA class IV heart failure, unstable angina, etc.)\n* Pregnancy\n* Severe cognitive impairment, defined as a MoCa score ≤ 12\n* Severe visual impairment or blindness","70 Years",{"count":149,"type":20},156,[23],"The aim of the study is to investigate the effectiveness of three different types of intervention, based on physical exercise and\u002For cognitive stimulation or training, on quality of life, cognition and mobility, on a population of older adults, who are most at risk of functional and cognitive decline",[153],"Elderly (People Aged 65 or More)",[155,156,157,158],"elderly","exercise","cognitive training","quality of life",{"date":133,"type":34},{"date":161,"type":34},"2025-11-15",{"date":163,"type":20},"2028-10-31",{"name":40,"class":41},{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":171,"eligibilityCriteria":172,"healthyVolunteers":11,"sex":17,"minAge":173,"maxAge":4,"enrollmentInfo":174,"targetDuration":4,"studyType":21,"phases":176,"briefSummary":177,"conditions":178,"keywords":180,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":192},"100602073","home-based-empowerment-through-physical-exercise-assisted-by-technology-for-frail-patients-100602073","NCT07118761","Home-based Empowerment Through Physical Exercise Assisted by Technology for Frail Patients","Frailty Status in Hospitalized Persons: Artificial Intelligence-based Detection and Technology-assisted Home-based Empowerment (ART.I.DE.)","ARTIDE","Inclusion Criteria:\n\n* Frail condition as determined by a Fried Frailty Score equal or more than 2,\n* Barthel Index \\> 60\n* Ability to ambulate also with assistance\n* Ability to communicate with the research team\n* Ability to use a smartphone or a tablet.\n\nExclusion Criteria:\n\n* terminal illness;\n* life-threatening conditions;\n* absolute contraindications to exercise training (e.g. fracture);\n* severe cognitive decline identified by a Mini-mental status examination \\\u003C 18;\n* incapability or unwillingness to provide informed consent.","65 Years",{"count":175,"type":20},120,[23],"This project, that lays in Health Ageing mission promoted by European Commission, aims to address the issue of frailty, a condition that poses the elderlies to increased vulnerability, deconditioning, and, ultimately, loss of independence. Frail people are exposed to a significant increase in mortality, hospitalizations and falls, with high burden for families and for the National Health Service (NHS). Nowadays, the detection of frailty is performed with more than 75 validated measures including questionnaires, scales and technologies. Moreover, frailty is usually not properly addressed, due to the limited resources in terms of personnel and programs in the NHS, and the frail patient is at high risk to be institutionalized and to definitely lose his functional independence. The project here proposed aims to address these topics, by combining clinical, rehabilitation, and engineering expertise in a unique team.\n\nIndeed, the projects aims to empower the frail people with an home-based app-guided rehabilitation program. In order to easily develop a largely tested home-based walking program, we aim to design and develop an application, compatible with any device, that will enable each person to easily exercise at home just few minutes per day. Through a randomized-controlled clinical trial, we will verify the effectiveness of the rehabilitation program on frailty status, in promoting patients' independence, quality of life and ARTIDE score.",[179],"Frailty",[181,182,183,128,179],"Exercise","Technology","Home-based training","2025-08-05",{"date":186,"type":34},"2025-08-12",{"date":188,"type":20},"2025-08-15",{"date":190,"type":20},"2028-07-14",{"name":40,"class":41},2,{"id":194,"slug":195,"hasResults":11,"nctId":196,"briefTitle":197,"officialTitle":198,"acronym":199,"eligibilityCriteria":200,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":201,"enrollmentInfo":202,"targetDuration":4,"studyType":21,"phases":203,"briefSummary":204,"conditions":205,"keywords":207,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":66},"100597467","unravelling-the-optimisation-and-consolidation-of-motor-skills-in-people-with-multiple-sclerosis-with-mild-to-moderate-gait-impairment-a-feasibility-study-100597467","NCT07058870","Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Mild to Moderate Gait Impairment: A Feasibility Study","Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Mild to Moderate Gait Impairment Via High Intensity Task Oriented Circuit Training: A Feasibility Study","UNLOCK MS MGI","Inclusion Criteria:\n\n* Diagnosis of primary or secondary progressive multiple sclerosis according to the McDonald criteria.\n* Mini-Mental State Examination (MMSE) score \\> 24.\n* Expanded Disability Status Scale (EDSS) score ≤ 6.\n\nExclusion Criteria:\n\n* Presence of other psychiatric or neurological disorders.\n* Cardiopulmonary, renal, or liver diseases.\n* Pregnancy.\n* Modifications in drug treatment within the last 3 months.","75 Years",{"count":5,"type":20},[23],"The goal of this feasibility study is to test the safety and effectiveness of an high-intensity task oriented circuit training program, followed by three months of telerehabilitation in people with mild to moderate Multiple Sclerosis (MS). The main questions it aims to answer are:\n\n* Can high-intensity task oriented circuit training improve gait and balance functional capacity?\n* Can telerehabilitation mantain the benefits in gait and balance gained via circuit training for a six month period?\n\nParticipants will:\n\n* Complete 10 session ( one hour each, three times a week) of high-intensity task oriented circuit training administered in a hospital setting. The training will target key motor skills such as walking, stepping, supine to stand transitions and general mobility.\n* Engage in 3 months of asynchronous telerehabilitation (without physiotherapist supervision)",[206],"Multiple Sclerosis",[208,209,210,211],"high intensity training","multiple sclerosis","motor learning","mild to moderate multiple sclerosis","2025-06-30",{"date":214,"type":34},"2025-07-10",{"date":216,"type":34},"2024-10-15",{"date":218,"type":20},"2026-02-28",{"name":40,"class":41},{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":226,"eligibilityCriteria":227,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":201,"enrollmentInfo":228,"targetDuration":4,"studyType":21,"phases":229,"briefSummary":230,"conditions":231,"keywords":232,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":237,"startDateStruct":238,"completionDateStruct":240,"leadSponsor":242,"locationsCount":66},"100597469","unravelling-the-optimisation-and-consolidation-of-motor-skills-in-people-with-multiple-sclerosis-with-severe-gait-impairment-a-feasibility-study-100597469","NCT07058896","Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Severe Gait Impairment: A Feasibility Study","Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Severe Gait Impairment Via High Intensity Task Oriented Circuit Training: A Feasibility Study","UNLOCK MS SGI","Inclusion Criteria:\n\n* Diagnosis of primary or secondary progressive multiple sclerosis according to the McDonald criteria.\n* Mini-Mental State Examination (MMSE) score \\> 24.\n* Expanded Disability Status Scale (EDSS) score ≥ 6.5.\n\nExclusion Criteria:\n\n* Presence of other psychiatric or neurological disorders.\n* Cardiopulmonary, renal, or liver diseases.\n* Pregnancy.\n* Modifications in drug treatment within the last 3 months.",{"count":5,"type":20},[23],"Multiple sclerosis (MS) is a progressive neurological disorder that often leads to severe gait impairment, limiting mobility and reducing the patient's quality of life. Motor rehabilitation has shown positive effects in people with MS (PwMS), but its efficacy tends to decrease as disability severity increases. High-intensity, task-oriented circuit training based on the principles of motor learning has been proposed as a potential strategy to improve motor function in severely impaired individuals.\n\nThis approach combines the benefits of high-intensity training to the motor learning principles to enhance motor skills improvement and retention.\n\nThe main questions it aims to answer are:\n\n* Can high-intensity, task oriented training in PwMS with severe gait impairment be feasible, safe and effective in enhancing motor function?\n* Can telerehabilitation maintain the benefits in gait and balance gained via circuit training for a six month period?\n\nParticipants will:\n\n* Complete 12 session ( three hour each, three times a week) of high-intensity task oriented circuit training administered in a hospital setting. The training will target key motor skills such as walking, stepping, sit to stand, wheelchair, standing and bed mobillity.\n* Engage in 3 months of asynchronous telerehabilitation (without physiotherapist supervision), including monthly televisits.",[206],[209,208,210,233,234,235,236],"circuit training","rehabilitation","balance","mobility",{"date":214,"type":34},{"date":239,"type":34},"2024-10-28",{"date":241,"type":20},"2025-10-31",{"name":40,"class":41},{"id":244,"slug":245,"hasResults":11,"nctId":246,"briefTitle":247,"officialTitle":248,"acronym":249,"eligibilityCriteria":250,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":251,"enrollmentInfo":252,"targetDuration":4,"studyType":21,"phases":253,"briefSummary":254,"conditions":255,"keywords":258,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":267,"completionDateStruct":269,"leadSponsor":271,"locationsCount":42},"100563830","exercise-activity-to-improve-mobility-in-patients-with-ckd-and-pad-100563830","NCT06621264","Exercise Activity to Improve Mobility in Patients With CKD and PAD","EXercise ACTivity to Improve Mobility, Active Behavior and Quality of Life of Chronic Kidney Disease Patients With Peripheral Artery Disease: the EXACTckd-pad Multicenter Randomized Controlled Trial","EXACT-CKDPAD","Inclusion Criteria:\n\n* chronic kidney disease at KDOQI stages III or IV and concomitant Peripheral artery disease at stages I, II, III;\n* ability to walk independently;\n* cognitive function to give informed consent identified by a Mini Mental Status Examination score greater or equal to 20\u002F30\n* absence of clinical conditions contraindicating exercise therapy (e.g., unstable angina, severe heart failure at NYHA class IV, anemia with lower than 10.0 g\u002Fdl).\n\nExclusion Criteria:\n\n* major amputations;\n* major surgery planned in the next 3 months;\n* known comorbid conditions that may limit survival to less than 2 years;\n* inability or unwillingness to comply with protocol requirements.","80 Years",{"count":124,"type":20},[23],"People affected by chronic kidney disease and concomitant diagnosed peripheral artery disease at intermediate stages, without contraindications to exercise therapy will be invited to participate in the study.\n\nWhose providing informed consent, will be randomly assigned to one of two groups:\n\n1. Exercise program receiving two daily 10-minute interval walking sessions at a slow increasing speed.\n2. Control group: receiving usual care including optimal medical therapy and nutritional advice.\n\nPatients of both groups will be measured at baseline, after the end of the exercise program (6-month) and at follow up (12-month). Outcome measures will include walking ability by the 6-minute walking test (primary outcome) and lower limbs perfusion, body composition, quality of life, laboratory outcomes and long-term hospitalizations.",[256,257],"Chronic Kidney Disease Stage 3 and 4","Peripheral Artery Disease (PAD)",[259,260,261,262,263],"Exercise therapy;","Mobility","Ageing","Chronic Kidney Disease","Peripheral artery disease","2025-05-30",{"date":266,"type":34},"2025-05-31",{"date":268,"type":34},"2024-10-01",{"date":270,"type":20},"2026-12-31",{"name":40,"class":41},{"id":273,"slug":274,"hasResults":11,"nctId":275,"briefTitle":276,"officialTitle":277,"acronym":278,"eligibilityCriteria":279,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":280,"targetDuration":4,"studyType":21,"phases":282,"briefSummary":283,"conditions":284,"keywords":286,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":66},"100592382","dynamic-perturbation-training-for-home-based-upper-limb-rehabilitation-in-chronic-stroke-100592382","NCT06992700","Dynamic Perturbation Training for Home-Based Upper Limb Rehabilitation in Chronic Stroke","Dynamic Perturbation Training for Home-Based Upper Limb Rehabilitation in Chronic Stroke: A Randomized Controlled Trial","PER ASPERA","Inclusion Criteria:\n\n* Males and females aged 18 years or older;\n* Diagnosis of first cerebral stroke (ischaemic or haemorrhagic) in the chronic phase (i.e. at least 6 months after the onset of the acute event) verified by brain imaging (brain computed tomography and\u002For magnetic resonance imaging);\n* Motor deficit in the upper limb - and in particular in the hand - caused by stroke, not attributable to other conditions or diseases and not such as to preclude the ability to perform movements with the fingers and to perform movements to grasp objects;\n* Ability to express informed consent correctly.\n* Availability of a webcam and Internet connection at home for remote supervision of activities by the staff involved in the study.\n\nExclusion Criteria:\n\n* Medical conditions that may interfere with the ability to safely complete the study protocol;\n* Cognitive dysfunction that precludes informed consent;\n* Severe neuropsychological disorders;\n* Severe visual problems;\n* Upper limb pain assessed with Visual Analogue Scale (VAS) \\> 7;\n* Severe internal diseases (e.g. cardiopulmonary, renal, hepatic);\n* Diseases with inflammatory skin lesions, wounds, sensory and circulatory disorders below the elbow and on the hand in the area of application;\n* Contraindications to transcranial magnetic stimulation (TMS) procedures, assessed as indicated by international reference, such as: presence of intracranial metal implants, positive history of epilepsy, frequent migraines, implantable devices (ventricular-peritoneal shunts, pacemakers, intrathecal pumps, intracranial metal implants). It should be noted that the presence of this type of exclusion criterion will preclude the performance of TMS assessments, but not the remaining procedures of the study;\n* Pregnancy.",{"count":281,"type":20},52,[23],"Study procedures: After acquiring clinical-demographic, neurophysiological and clinical-functional data to describe the extent of upper limb impairment at baseline at the facilities of the Rehabilitation Medicine Unit (UMR) of the Ferrara University Hospital (Department of Neuroscience), patients will undergo a 10-day home rehabilitation programme (two consecutive weeks, five days a week, two daily sessions of one hour each) with remote supervision by study staff in a randomised manner in two groups:\n\n* Experimental group: patients in this group will perform the exercises at at home with the paretic upper limb wearing the orthosis, © Aurafix, model ORT-07A, characterised by elastic bands that exert resistance on the distal phalanx of the fingers.\n* Control group: patients in this group will perform the exercises at home with the paretic upper limb wearing the orthosis (in order to stabilise the wrist and eliminate this potential confounding variable) but without the springs that provide resistance (i.e. eliminating the elastic resistance that is the subject of this study); Assignment to the treatment group will be based on a randomisation list (generated through https:\u002F\u002Fwww.random.org\u002F to obtain a balanced division) established by the Scientific Director of the study and communicated exclusively to the personnel involved in administering the treatment sessions, while it will not be disclosed to the personnel involved in the other phases of the study. This will allow for the division of patients and an evaluation of the effectiveness of the treatment between the two groups to be as objective as possible. At the end of the ten days of treatment, patients will return to the facilities of the UMR of the Ferrara University Hospital and repeat the assessments already carried out at baseline, in order to evaluate pre\u002Fpost performance differences after the home treatment and the differences between the two groups. Finally, questionnaires will be administered to assess fatigue at the end of each day of treatment and patient satisfaction in relation to this telerehabilitation approach at the end of the ten days. It should be noted that patients allocated to the control group will be offered the opportunity to undergo the same treatment as the experimental group, i.e. using the orthosis, in order to ensure that all participants have an equal opportunity to benefit from the innovative protocol.\n\nType of subjects to be enrolled: Subjects diagnosed with chronic cerebral stroke (i.e. at least 6 months after the onset of the acute event) among patients attending the UMR of the Ferrara University Hospital on an outpatient\u002Fday-hospital basis for current or previous multidisciplinary rehabilitation treatment specific to the needs of the individual patient.\n\nInformation\u002FConsent: Each participant will be assessed to determine their preliminary eligibility, informed about the aim and procedures of the study, provided with all necessary information for possible participation in the study and sign the informed consent form.\n\nSuspension procedure: At any time during the trial, participants may suspend or withdraw from the study at their own discretion. Breaks during the sessions are also provided for if the participant experiences fatigue, which is the only expected adverse effect, in line with what generally found in any form of repeated physical exercise. Such suspensions will be granted whenever requested, in order to alleviate the participant's discomfort and promote their full participation in the treatment sessions.",[285],"Stroke",[285,287],"Neurorehabilitation","2025-05-19",{"date":290,"type":34},"2025-05-28",{"date":292,"type":34},"2025-03-15",{"date":294,"type":20},"2027-06",{"name":40,"class":41},{"id":297,"slug":298,"hasResults":11,"nctId":299,"briefTitle":300,"officialTitle":300,"acronym":4,"eligibilityCriteria":301,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":302,"targetDuration":304,"studyType":54,"phases":4,"briefSummary":305,"conditions":306,"keywords":312,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":314,"lastUpdatePostDateStruct":315,"startDateStruct":317,"completionDateStruct":319,"leadSponsor":321,"locationsCount":66},"100585126","utility-of-gene-test-analysis-for-diagnosis-prognosis-and-treatment-of-patients-with-genetic-arrhythmic-heart-disease-the-arrhythmic-gene-heart-100585126","NCT06898307","Utility of Gene Test Analysis for Diagnosis, Prognosis and Treatment of Patients With Genetic Arrhythmic Heart Disease: the ARRHYTHMIC GENE-HEART","Inclusion Criteria:\n\n* Patients evaluated at the Cardiogenetic Center of the University of Ferrara in Ferrara, Italy.\n* Having a proven cardiogenetic disease\n\nExclusion Criteria:\n\n* Refuse to provide informed consents\n* Patients not having a cardiogenic disease",{"count":303,"type":20},200,"10 Years","The goal of this observational study is to enroll all patients evaluated at the specialized Cardiogenetic Center within the Cardiology Department of the University of Ferrara, Italy. The primary aim of the registry is to collect comprehensive clinical, genetic, and electrophysiological data from individuals with suspected or confirmed arrhythmogenic conditions. By systematically documenting patient demographics, family history, clinical presentations, diagnostic findings, and treatment outcomes, the registry seeks to enhance our understanding of the genetic basis and clinical implications of genetically driven arrhythmias and systemic syndromes. This registry will facilitate long-term follow-up of enrolled patients to assess the natural history of arrhythmogenic disorders and the effectiveness of various therapeutic interventions. Additionally, it aims to identify potential risk factors associated with adverse outcomes, such as sudden cardiac death or major arrhythmic events.",[307,308,309,310,311],"Genetic Disease","Cardiac Disease","Cardiac Arrhythmias","Genetic Disorder","Cardiology",[313],"Cardiogenetic","2025-03-26",{"date":316,"type":34},"2025-03-27",{"date":318,"type":34},"2017-11-01",{"date":320,"type":20},"2035-11-01",{"name":40,"class":41},{"id":323,"slug":324,"hasResults":11,"nctId":325,"briefTitle":326,"officialTitle":327,"acronym":4,"eligibilityCriteria":328,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":251,"enrollmentInfo":329,"targetDuration":4,"studyType":21,"phases":331,"briefSummary":332,"conditions":333,"keywords":335,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":341,"lastUpdatePostDateStruct":342,"startDateStruct":344,"completionDateStruct":346,"leadSponsor":348,"locationsCount":66},"100584710","using-immersive-virtual-reality-for-the-upper-limb-rehabilitation-of-post-stroke-subjects-100584710","NCT06892886","Using Immersive Virtual Reality for the Upper Limb Rehabilitation of Post-stroke Subjects","Using Immersive Virtual Reality for the Upper Limb Rehabilitation of Post-stroke Subjects: a Multicenter Randomized Control Trial","Inclusion Criteria:\n\n* diagnosis of first, ischemic or hemorrhagic, stroke verified by brain imaging within 4 week\n* upper limb motor impairment defined by an upper extremity score \\\u003C55 on the Fugl-Meyer Assessment\n\nExclusion Criteria:\n\n* neurological conditions in addition to stroke that may affect motor function\n* other medical conditions likely to interfere with the ability to safely complete the study protocol\n* impaired cognitive functioning that influences the ability to give informed consent\n* severe neuropsychological disorders\n* visual impairment\n* severe upper-limb pain defined as \\> 7 on the Visual Analogue Scale",{"count":330,"type":20},48,[23],"Stroke produces brain damages that results in sensory, motor, and cognitive impairments which reduce the patient's quality of life and social participation. Upper limb recovery is a complex process whose goal is to allow the patients to gain, in part or completely, independence in daily living activities, for that it represents one of the most important rehabilitation focus. Virtual reality is a fairly recent approach able to simulate concrete movements and functional tasks in a higher dosage compared to other therapies. It seems that the use of VR could improve limb function, however, the amount of this gain is still unclear because of insufficient evidence. This study aims at quantitatively investigating the effectiveness of an HMD immersive virtual reality system on the upper limb functioning in subacute stroke survivors.",[334],"Sub-acute Stroke",[336,234,337,338,339,340],"stroke","upper limb","immersive virtual reality","head-mounted display","subacute stroke","2025-03-17",{"date":343,"type":34},"2025-03-25",{"date":345,"type":34},"2023-03-01",{"date":347,"type":20},"2025-12-31",{"name":40,"class":41},{"id":350,"slug":351,"hasResults":11,"nctId":352,"briefTitle":353,"officialTitle":354,"acronym":355,"eligibilityCriteria":356,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":357,"enrollmentInfo":358,"targetDuration":4,"studyType":21,"phases":360,"briefSummary":361,"conditions":362,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":365,"startDateStruct":367,"completionDateStruct":369,"leadSponsor":371,"locationsCount":192},"100547770","comparison-of-the-diagnostic-accuracy-us-guided-percutaneous-lung-biopsies-vs-ct-guided-in-peripheral-lung-lesions-100547770","NCT06412289","Comparison of the Diagnostic Accuracy: US-guided Percutaneous Lung Biopsies vs CT-guided in Peripheral Lung Lesions","A Prospective, Randomized, Multicentric and Single-blinded Study on Accuracy and Safety of Ultrasound (US) Guided Percutaneous Needle Biopsy of Peripheral Lung Lesion Compared With Computed TomogrAphy (CT) Guided Needle Biopsy","SULTAN","Inclusion Criteria:\n\n* Willingness and ability to provide free and informed consent. Age older then 18 years old.\n* Peripheric pulmonary lesions adherent to the thoracic wall in CT scans with indication to typing\n\nExclusion Criteria:\n\n* Inability to provide free and informed consent, in the absence of an available legal guardian.\n* Age younger then 18 years old.\n* Terminal neoplastic diseases\u002F palliative care patients.\n* Patients with one lung, anatomical of functional.\n* Severe non-treatable blood clothing disfunctions.\n* Severe organ failure (pulmonary, renal, hepatic or cardiac).\n* Women in state of pregnancy.","90 Years",{"count":359,"type":20},236,[23],"A non-sponsored prospective randomized single-blind national multicenter interventional study which aims to compare the diagnostic accuracy between US-guided percutaneous lung needle biopsies and CT-guided in peripheral lung lesions. Secondary endpoints are:\n\n* onset of number and type of complications during and after the procedure, within the first three hour;\n* exposition to ionizing radiation, in milligray(mGy);\n* patient comfort during the procedure;\n* duration of the procedure,",[363],"Peripheral Lung Lesions","2024-12-03",{"date":366,"type":34},"2024-12-06",{"date":368,"type":34},"2024-03-08",{"date":370,"type":20},"2026-10-31",{"name":40,"class":41},{"id":373,"slug":374,"hasResults":11,"nctId":375,"briefTitle":376,"officialTitle":377,"acronym":378,"eligibilityCriteria":379,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":380,"enrollmentInfo":381,"targetDuration":4,"studyType":21,"phases":383,"briefSummary":384,"conditions":385,"keywords":389,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":396,"startDateStruct":398,"completionDateStruct":400,"leadSponsor":402,"locationsCount":192},"100561390","non-pharmacological-care-for-depression-in-cancer-patients-using-vr-and-tms-100561390","NCT06589544","Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS","Cost-effectiveness of Transcranial Magnetic Stimulation and Virtual Reality Based Cognitive Remediation on Depressive Symptoms Among Cancer Patients: a Three-arm Randomized Clinical Trial.","INCEPT","Inclusion Criteria:\n\n* Diagnosis of oncological disease in the last 5 years\n* Diagnosis of Major Depressive Disorder, without psychotic symptoms, according to DSM-5 criteria\n* 17-item Hamilton Rating Scale for Depression (HAM-D-17) (score ≥14)\n* Age: 18 years or older\n* Oncological disease in a non-advanced stage (Karnofsky Performance Status \\> 80)\n\nExclusion Criteria:\n\n* Current or prior hospitalization in the next 6 months\n* Planned surgery in the next 6 months\n* Suicidal ideation\n* Substance use\n* History of significant head trauma, neurological disorders, intellectual deficits\n* Recurrent seizures resulting from head trauma or conditions lowering seizure threshold\n* Concurrent use of medications that increase the risk of epileptic seizures (e.g., antipsychotics, tricyclics, theophylline)\n* Glaucoma, retinal detachment, or other serious vision impairments that may prevent the use of virtual reality technology\n* Severe problems with autonomous ambulation","100 Years",{"count":382,"type":20},100,[23],"Despite its significant impact on individuals and healthcare systems, substantial gaps remain in the clinical and rehabilitative management of depression in oncology patients.\n\nDepression in cancer patients is often under-recognized and untreated, and screening tools and structured healthcare pathways are lacking. Even when depression is identified in oncology patients, evidence of effective treatments is limited. There are no specific guidelines for psychotropic drug use in cancer patients, and antidepressant efficacy is uncertain despite their frequent use.\n\nEmerging strategies like transcranial magnetic stimulation and cognitive rehabilitation show promising findings. However, the cost-effectiveness of therapeutic strategies is understudied.\n\nRepetitive transcranial magnetic stimulation (rTMS) is already used for the treatment and relapse prevention of depression both as monotherapy and as an add-on to antidepressant pharmacotherapy, and it appears effective in improving cognitive performance. However, it has not yet been applied to treat depressive disorders in oncology patients.\n\nVirtual reality-based cognitive behavioral intervention (VR-COG) is designed to improve cognitive functioning, a central feature of depression in oncological conditions. VR-COG enhances learning and skill acquisition with better ecological efficiency than traditional cognitive remediation programs. VR approaches are well-received by oncology patients and show promise in reducing anxiety and depressive symptoms.\n\nThe trial aims to evaluate the effectiveness of highly specialized, nonpharmacological interventions on depressive symptoms and quality of life in oncology patients. Specifically, repetitive Transcranial Magnetic Stimulation (rTMS) and Virtual Reality-based Cognitive Remediation (VR-COG) will be analyzed, alongside standard Treatment as Usual (TAU), in comparison to TAU alone. This trial also aims at evaluate cognitive functioning, depression-related conditions and the cost-effectiveness of the interventions under study.",[386,387,388],"Depressive Symptoms","Quality of Life","Cognitive Impairment",[390,391,387,392,393,394],"Depression","Cognitive functions","Cancer","Virtual reality","Repetitive Transcranial Magnetic Stimulation","2024-09-09",{"date":397,"type":34},"2024-09-19",{"date":399,"type":34},"2024-08-21",{"date":401,"type":20},"2027-12-31",{"name":40,"class":41},{"id":404,"slug":405,"hasResults":11,"nctId":406,"briefTitle":407,"officialTitle":408,"acronym":409,"eligibilityCriteria":410,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":411,"targetDuration":304,"studyType":54,"phases":4,"briefSummary":413,"conditions":414,"keywords":419,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":428,"lastUpdatePostDateStruct":429,"startDateStruct":431,"completionDateStruct":433,"leadSponsor":435,"locationsCount":42},"100540000","multicenter-evaluation-of-patients-using-latitude-monitoring-system-100540000","NCT06311149","Multicenter Evaluation of Patients Using LATITUDE Monitoring System","Multicenter Evaluation of Patients Using LATITUDE Monitoring System: Multitude Study","Multitude","Inclusion Criteria:\n\n* Subject is willing and capable of providing informed consent to collect\u002Fstore\u002Fprocess personal health information by the sponsor or such consent is provided by a legally designated representative, if required by local law or regulation.\n* Subject is:\n\n  1. prospectively scheduled for receiving a device monitored through the LATITUDE monitoring system\n  2. retrospectively enrolled after having received a device monitored through the LATITUDE monitoring system\n\nExclusion Criteria:\n\n* Subject foreseen not to be followed at the enrolling center for at least 1 year after having received the device.\n* Subject is receiving a device that is not approved for commercial use at the time of procedure.",{"count":412,"type":20},20000,"The Multitude is a registry of patients who receive commercially available CIEDs that remotely communicate through the LATITUDE monitoring system and transfer data to a central database.\n\nThe registry is designed to constitute a shared environment for the collection, management, analysis and reporting of clinical and diagnostic data, adopted by a network of European scientifically-motivated physicians who use rhythm management diagnostic and therapeutic solutions from Boston Scientific in their clinical practice.\n\nThe Multitude study will facilitate the sharing of scientific proposals within a large network of researchers, and it will allow researchers to record the experience with medical devices throughout the device and patient lifecycle.",[415,416,417,418],"Cardiovascular Diseases","Arrhythmias, Cardiac","Heart Failure","Sudden Cardiac Death",[420,421,422,423,424,425,426,427],"Cardiac implantable electrical device","Implantable cardioverter defibrillator","Pacemaker","Cardiac resynchronization therapy","Subcutaneous defibrillator","Implantable cardiac monitor","Remote monitoring","Latitude monitoring system","2024-08-08",{"date":430,"type":34},"2024-08-12",{"date":432,"type":34},"2023-12-01",{"date":434,"type":20},"2043-12-31",{"name":40,"class":41},{"id":437,"slug":438,"hasResults":11,"nctId":439,"briefTitle":440,"officialTitle":441,"acronym":442,"eligibilityCriteria":443,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":444,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":446,"conditions":447,"keywords":471,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":483,"lastUpdatePostDateStruct":484,"startDateStruct":486,"completionDateStruct":488,"leadSponsor":489,"locationsCount":490},"100541040","contemporary-cardiac-stimulation-in-clinical-practice-left-biventricular-right-and-conduction-system-pacing-100541040","NCT06324682","ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","Evaluation of conTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","TREEBEARD","Inclusion Criteria:\n\n* Indication for cardiac stimulation\n* Having performed the implantation of a device for cardiac stimulation\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years;\n* Pregnancy status;",{"count":445,"type":20},8400,"The goal of this observational study is to evaluate the clinical characteristics of patients undergoing permanent cardiac pacing and to compare procedural efficacy and safety of different implantation approaches in the clinical practice of the participating centres. The contribution of non-fluoroscopic anatomical and electrophysiological reconstruction systems to device implantation procedures will also be evaluated.\n\nParticipants \\[patients over 18 years old with an indication to receive a definitive pacemaker\u002Fintracardiac defibrillator implant\\] will receive a permanent cardiac pacing implant as requested according to European Society of Cardiology (ESC) guidelines; the investigators will evaluate procedural efficacy and safety of different implantation approaches.",[416,448,449,99,450,451,452,453,454,455,456,457,458,459,460,461,462,463,464,465,466,467,468,469,470],"Atrioventricular Block","Reduced Systolic Function","Bradyarrhythmia","Ventricular Tachycardia","Ventricular Dysfunction","Ventricular Fibrillation","Ventricular Arrythmia","Atrioventricular Nodal Disease","Atrioventricular Conduction Defects","Atrioventricular Block Complete","Atrioventricular Block Incomplete","Atrioventricular Junctional Rhythm","Bundle-Branch Block","Left Bundle-Branch Block","Heart Failure, Systolic","Block;Atrioventricular","Block; Arrhythmic","Block; Mobitz","Block, Heart","Block, Fascicular","Block Branch Bundle Left","Heart Failure，Congestive","Heart Arrhythmia",[472,473,448,450,452,474,475,476,477,478,479,480,481,457,482,454,453,451],"Pace maker (PM)","Implantable cardioverter defibrillator (ICD)","Cardiac Resynchronization therapy","Conduction System Pacing","His Pacing","Left bundle branch area pacing (LBBAP)","CRT","CSP","Primary prevention","Secondary prevention","Heart failure","2024-03-19",{"date":485,"type":34},"2024-03-22",{"date":487,"type":34},"2023-01-01",{"date":86,"type":20},{"name":40,"class":41},31,{"id":492,"slug":493,"hasResults":11,"nctId":494,"briefTitle":495,"officialTitle":496,"acronym":497,"eligibilityCriteria":498,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":499,"targetDuration":78,"studyType":54,"phases":4,"briefSummary":501,"conditions":502,"keywords":504,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":510,"lastUpdatePostDateStruct":511,"startDateStruct":513,"completionDateStruct":515,"leadSponsor":517,"locationsCount":66},"100242730","prospective-registry-of-acute-coronary-syndromes-in-ferrara-100242730","NCT02438085","Prospective Registry of Acute Coronary Syndromes in Ferrara","Acute coRonary sYndrOmes proSpective regisTry Of Ferrara","ARYOSTO","Inclusion Criteria:\n\n* age \\>18 years\n* hospital admission for acute coronary syndromes\n* resident in the Ferrara area\n\nExclusion Criteria:\n\n* none",{"count":500,"type":20},10000,"The ARYOSTO has been designed to describe the clinical epidemiology and the current management of acute coronary syndromes (ACS) in the area of Ferrara. Especially, the Authors will evaluate the medical and interventional management of ACS patients admitted to hospitals in the area of Ferrara and receiving coronary artery angiography and percutaneous coronary intervention (PCI) in the hub center of Ferrara (Azienda Ospedaliera Universitaria di Ferrara, Cona (FE), Italy)",[503],"Acute Coronary Syndromes",[505,506,507,508,509],"acute coronary syndromes","outcome","medical management","comorbidities","registry","2023-11-12",{"date":512,"type":34},"2023-11-14",{"date":514,"type":34},"2014-06",{"date":516,"type":20},"2032-11-30",{"name":40,"class":41},""]