[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Alabama, Tuscaloosa\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":290},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,51,84,110,139,167,189,217,243,269],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100613920","the-impact-of-brief-behavioral-treatment-for-insomnia-versus-brief-mindfulness-treatment-on-cognition-and-sleep-health-in-adults-age-50-with-hiv-100613920",false,"NCT07272863","The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV","The Impact of BBTI on Cognition and Sleep Health in Older Adults With HIV","Inclusion Criteria:\n\n* must be age 50 or older\n* have a DSM-5 diagnostic criteria for insomnia including sleep difficulty that occurs at least 3 times per week and has been a problem for at least 3 consecutive months (indicated on the Structured Clinical Interview for Sleep Disorders, SCISD) during telephone screening\n* have a confirmed HIV diagnosis and a prescribed ART regimen for at least 12 months.\n\nExclusion Criteria:\n\n* unable to speak English\n* have a reported or documented (in medical records) diagnosis of AD or dementia\n* have severe neurocognitive impairment (\\>7 errors on the Short Portable Mental Status Questionnaire, SPMSQ) during telephone screening\n* have a history of a stroke\n* currently undergoing radiation\u002Fchemotherapy\n* reports a history of brain trauma with loss of consciousness greater than 30 minutes\n* have a learning disability\n* have a documented diagnosis of sleep apnea (in medical records)\n* reports use of a continuous positive airway pressure machine\n* have been identified as high risk for moderate to severe sleep apnea (Snoring, Tiredness, Observed sleep apnea, Pressure, BMI, Age, Neck circumference, and Gender, STOP BANG ≥ 5) during telephone screening\n* have restless leg syndrome and\u002For have narcolepsy\n* have a documented history of bipolar disorder or psychotic disorder\n* not be receiving efavirenz as part of their current ART regimen","ALL","50 Years","99 Years",{"count":20,"type":21},214,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to examine the effects of a telephone-delivered Brief Behavioral Treatment Insomnia (BBTI) versus a Brief Mindfulness Treatment (BMT) on cognitive and sleep outcomes in older adults with HIV. The main questions it aims to answer are:\n\nWhat are the effects of BBTI vs BMT on self-reported and observed sleep outcomes in older adults with HIV and insomnia up to 1-year post-intervention? What are the effects of BBTI vs BMT on self-reported and observed cognitive comes in older adults with HIV and insomnia up to 1-year post-intervention? What is the association between Alzheimer's Disease biomarkers and sleep and cognitive outcomes in older adults with HIV receiving BBTI vs BMT?\n\nParticipants will:\n\n* Complete 4 weeks of telephone-delivered BBTI or BMT\n* Attend baseline, post-intervention, and 1-year post in-person visits for sleep and cognitive assessments\n* Have blood collected at all three time points",[27,28,29,30],"Insomnia","Cognition","Aging","HIV",[32,33,34,30,35,36,37],"insomnia","cognition","older adults","Alzheimer's Disease","brief behavioral treatment","randomized control trial","NOT_YET_RECRUITING","2026-05-07",{"date":41,"type":42},"2026-05-08","ACTUAL",{"date":44,"type":21},"2026-05",{"date":46,"type":21},"2030-09",{"name":48,"class":49},"University of Alabama, Tuscaloosa","OTHER",2,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":16,"minAge":60,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},"100624886","evaluating-the-impact-of-sky-breath-meditation-on-stress-well-being-and-connection-in-college-students-100624886","NCT07415460","Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students","Breath of Resilience: Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students - A Pilot Feasibility Randomized Controlled Trial","SKY Breath","Inclusion Criteria:\n\n* Participants must:\n\n  1. be currently enrolled as undergraduate or graduate students at the university in Alabama;\n  2. be at least 18 years old;\n  3. speak and read English;\n  4. be available to attend a 3-day in-person retreat and twice-weekly online sessions for SKY breath program over 8 weeks;\n  5. be able to provide informed consent.\n\nExclusion Criteria:\n\n* Participants will be excluded if they:\n\n  1. have a serious psychiatric condition (e.g., schizophrenia, psychotic disorders) that could be exacerbated by group-based interventions;\n  2. are in acute psychiatric crisis; such as, active suicidal ideation\n  3. have acute medical conditions that contraindicate light physical activity or breathwork;\n  4. are unable to obtain physician clearance for participation due to chronic conditions (e.g., uncontrolled asthma, severe cardiovascular disease, active psychiatric illness requiring intensive treatment).",true,"18 Years",{"count":62,"type":21},53,[24],"This pilot study will evaluate the feasibility and potential benefits of Sudarshan Kriya Yoga (SKY) for university students. Over an eight-week period, 56 students will be randomly assigned to either a SKY breathwork group or a control group engaging in general yoga without breathwork. The SKY group will participate in a three-day in-person retreat, weekly virtual sessions, and independent home practice. The study will assess recruitment, retention, and adherence, as well as changes in physical activity, perceived stress, anxiety, resilience, social connectedness, and cognitive focus. All participants will complete validated wellness questionnaires at baseline and post-intervention. The goal is to determine whether SKY is a feasible, low-risk intervention that may enhance student well-being and inform future research.",[66,67,68],"Stress","Anxiety","Physical Activity",[70,71,72,73],"SKY Breath Meditation","perceived stress scale","GAD-7","IPAQ-short form","RECRUITING","2026-04-27",{"date":77,"type":42},"2026-04-29",{"date":79,"type":21},"2026-08-28",{"date":81,"type":21},"2027-04-30",{"name":48,"class":49},1,{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":59,"sex":16,"minAge":60,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":22,"phases":93,"briefSummary":94,"conditions":95,"keywords":98,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":50},"100582512","assessing-pharmacy-technician-educational-training-for-the-provision-of-over-the-counter-hearing-aids-in-rural-alabama-and-mississippi-pharmacies-100582512","NCT06864273","Assessing Pharmacy Technician Educational Training for the Provision of Over-the-Counter Hearing Aids in Rural Alabama and Mississippi Pharmacies","Increasing Access to Hearing Healthcare: An Assessment of Pharmacy Technician Educational Training for the Provision of Over-the-Counter Hearing Aids in Rural Alabama and Mississippi Pharmacies","Inclusion Criteria:\n\n1. Pharmacy technicians licensed to practice in the state of Alabama or Mississippi.\n2. Pharmacy technicians who practice in rural communities of Alabama and Mississippi.\n3. Adults 18 years of age with mild to moderate hearing loss and who live in rural communities of Alabama or Mississippi.\n\nExclusion Criteria:\n\n1. Pharmacy technicians with hearing loss who could have prior understanding of care for those with hearing loss will not be included in the study.\n2. Adults 18 years of age or older with typical hearing will not be included in the study.\n3. Adults with hearing loss who live in urban areas of Alabama and Mississippi will not be included in the study.\n4. Participants will be excluded if they have any medical condition resulting in cognitive impairment that results in an inability to complete the study tasks (e.g., mental health condition, stroke, head injury, dementia, or Alzheimer's disease)",{"count":92,"type":21},144,[24],"Hearing loss is a major public health concern due to its negative association with emotional well-being, cognition, and physical ailments, such as diabetes. Access to audiologists and otolaryngologists in many regions across the US is poor or extremely limited. Rural populations are older, less educated, and have lower household incomes compared to populations in metropolitan areas. Also, with increasing age adults experience greater rates of hearing loss. Fortunately, the 2022 FDA Final Rule for Over-the-Counter Hearing Aids (OTC HAs) could revolutionize assess to hearing aids and hearing healthcare by allowing adults with perceived mild-to-moderate hearing loss to purchase these devices over the counter, without medical clearance or care from an audiologist. Pharmacies located in rural areas now have the option to provide OTC HAs, something previously not possible. Currently, however, there are no established guidelines for effective provision of these devices in pharmacies located in rural communities. Educating pharmacy technicians to provide basic hearing healthcare related to OTC HAs use could address a critical need and create a new care delivery model to ensure sustainable, long-term access to hearing healthcare. The long-term goal of this study is to create a sustainable interprofessional collaborative between audiologists and pharmacists for the development of a hearing healthcare model that improves access and affordability of care in rural regions across the country. The specific aims are to 1) Determine an effective approach for educating pharmacy technicians for the provision of OTC HAs in rural community pharmacies, and 2) Identify satisfaction of care provided by pharmacy technicians and initial performance with OTC HAs in adults with hearing loss living in rural communities. A stepped wedged clinical trial design will be used to study the effectiveness of a comprehensive educational training program for pharmacy technicians. Technicians from rural Alabama and Mississippi, placed within four different clusters, will participate in a multimodal training program for the purpose of developing basic clinical skills to assist adults with perceived mild-to-moderate hearing loss. Additionally, adults with hearing loss who receive clinical services from trained pharmacy technicians will be asked to report on the care they received and benefit from their OTC HAs. The central hypotheses are a) that pharmacy technician training will result in greater understanding of hearing healthcare concepts compared to no training, and b) the training will lead to successful provision of basic hearing healthcare to adults with hearing loss in rural communities. The expected outcome of this project will be the establishment of a multimodal education program, leveraging the increased access of OTC HAs, to support those with hearing loss in rural pharmacies across the county. The ability of pharmacy technicians to provide this support will dramatically increase the availability of hearing services in rural communities, which will positively impact the quality of life for those with hearing loss.",[96,97],"Bilateral Hearing Loss","Health Services Research",[99,100,101],"pharmacy education","rural health","Aids, Hearing","2025-08-08",{"date":104,"type":42},"2025-08-13",{"date":106,"type":42},"2025-07-25",{"date":108,"type":21},"2026-08-31",{"name":48,"class":49},{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":59,"sex":16,"minAge":60,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":22,"phases":120,"briefSummary":121,"conditions":122,"keywords":125,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":83},"100573411","strengthening-health-and-insight-in-new-educators-100573411","NCT06745934","Strengthening Health and Insight in New Educators","Healthy Minds for Pre-Service Teachers","SHINE","Inclusion Criteria:\n\n* Students in Block 3 will be invited to participate in the study.\n\nExclusion Criteria:\n\n* Students who are not in Block 3 will be excluded. Participants experiencing suicidal ideations at baseline and deemed via the clinical risk assessment procedure to be at moderate or high risk of suicide will be excluded from the study after baseline, and prior to randomization.",{"count":119,"type":21},140,[24],"Teachers are at notable risk for depression and anxiety. The present study tests an app-based mindfulness intervention for teachers in their final year of training with the goal of preventing the deterioration of their mental health during the transition into the classroom. The project will strengthen the research environment at the University of Alabama and will involve undergraduate research assistants in each step of the research process.",[123,124],"Anxiety Symptoms","Depressive Symptoms",[126,127,128,129,130],"Healthy Minds Program","mindfulness-based intervention","app","pre-service teachers","mental health","2025-03-31",{"date":133,"type":42},"2025-04-02",{"date":135,"type":42},"2025-01-17",{"date":137,"type":21},"2027-06",{"name":48,"class":49},{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":145,"eligibilityCriteria":146,"healthyVolunteers":11,"sex":16,"minAge":60,"maxAge":4,"enrollmentInfo":147,"targetDuration":4,"studyType":22,"phases":149,"briefSummary":150,"conditions":151,"keywords":153,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":83},"100513475","the-home-study-healthy-options-made-easy-telehealth-nutrition-sessions-for-people-living-with-brain-injury-100513475","NCT05965947","The HOME Study (Healthy Options Made Easy): Telehealth Nutrition Sessions for People Living With Brain Injury","Medical Nutrition Therapy and Diet Quality Among Survivors of Brain Injury - The HOME Study (Healthy Options Made Easy): Telehealth Nutrition Sessions for People Living With Brain Injury","HOME","Inclusion Criteria:\n\n* At least 18 years of age\n* History of brain injury\n* Live in Alabama\n* Live at home in the community\n* Have internet access to join Zoom sessions\n\nExclusion Criteria:\n\n* Under 18 years of age\n* No history of brain injury\n* Lives outside of Alabama\n* Currently in a hospital, rehabilitation facility, group home, or other location other than 'home'\n* Pregnant or breastfeeding\n* Not able\u002Fwilling to participate based on the Decision-Making Capacity Assessment",{"count":148,"type":21},134,[24],"Brain injury is a leading cause of disability in the United States. When survivors of brain injury recover from the initial injury and return home to live in the community, they often face chronic health conditions that warrant nutrition therapy, such as diabetes, high blood pressure, high cholesterol, and overweight and obesity. Typically, these individuals do not receive nutrition counseling.\n\nThus, the purpose of this clinical trial is to compare changes in diet quality between community-dwelling individuals with a history of brain injury who receive three individualized nutrition therapy sessions versus handouts only.\n\nOur research question is:\n\nCan nutrition counseling improve dietary intake among this population?\n\nParticipants will complete a survey, participate in three days of dietary recalls via Zoom or telephone, and receive either three individualized nutrition counseling sessions with a Registered Dietitian or standard of care (handouts).\n\nResearchers will compare the diets of the recipients of the nutrition counseling to a control group who receives nutrition handouts to see if nutrition sessions with a Registered Dietitian improve dietary intake.",[152],"Brain Injuries",[154,155,156,157,158],"brain injury","Medical Nutrition Therapy","Registered Dietitian","diet quality","Healthy Eating Index","2024-12-04",{"date":161,"type":42},"2024-12-09",{"date":163,"type":42},"2023-06-12",{"date":165,"type":21},"2025-10-31",{"name":48,"class":49},{"id":168,"slug":169,"hasResults":11,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":4,"eligibilityCriteria":173,"healthyVolunteers":59,"sex":16,"minAge":174,"maxAge":4,"enrollmentInfo":175,"targetDuration":4,"studyType":22,"phases":177,"briefSummary":178,"conditions":179,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":83},"100414037","improving-access-and-affordability-of-adult-hearing-healthcare-100414037","NCT04671381","Improving Access and Affordability of Adult Hearing Healthcare","Improving Access and Affordability of Adult Hearing Healthcare: Effectiveness of Community-based Interventions in West Central and South Alabama","Inclusion Criteria:\n\n* Mild-to-moderate hearing loss\n* Live in West Central or South Alabama\n* 40 years of age or older\n\nExclusion Criteria:\n\n• Medical conditions resulting in severe cognitive impairment (e.g., stroke, head injury, senile dementia or Alzheimer's disease)","40 Years",{"count":176,"type":21},210,[24],"This project will address quality of care issues associated with hearing loss in adults who have mild-to-moderate hearing loss and who have no access to hearing healthcare. Through the use of three different interventions involving over-the-counter hearing aids, it will lead to options that will increase access and affordability of hearing healthcare for adults with mild-to-moderate hearing loss.",[180],"Hearing Loss","2024-10-28",{"date":183,"type":42},"2024-10-30",{"date":185,"type":42},"2021-01-01",{"date":187,"type":21},"2025-12",{"name":48,"class":49},{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":59,"sex":16,"minAge":196,"maxAge":197,"enrollmentInfo":198,"targetDuration":4,"studyType":22,"phases":200,"briefSummary":201,"conditions":202,"keywords":204,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":209,"lastUpdatePostDateStruct":210,"startDateStruct":212,"completionDateStruct":214,"leadSponsor":216,"locationsCount":83},"100492725","steps-implementation-trial-100492725","NCT05695885","STEPS Implementation Trial","Stepped Transition in Education Program for Emerging Adults With Autism: Pilot Effectiveness Trial","Inclusion Criteria:\n\n* 16-25 years of age\n* have confirmed diagnosis of ASD\n* want to participate in STEPS\n* have a caregiver\u002Fparent who can complete assessments\n\nExclusion Criteria:\n\n* presence of suicidal\u002Fhomicidal intent","16 Years","25 Years",{"count":199,"type":21},80,[24],"This study will inform understanding of how to support emerging adults with autism spectrum disorder (ASD). The investigators will use a theoretically informed and research-based transition support program developed for people with ASD and test how effective it is when delivered by community agencies. Results will provide information on the effectiveness of the program as well as on mechanisms of change and contextual factors that promote or impede implementation.",[203],"Autism Spectrum Disorder",[205,206,207,208],"transition","adulthood","employment","education","2024-08-14",{"date":211,"type":42},"2024-08-16",{"date":213,"type":42},"2023-04-01",{"date":215,"type":21},"2025-12-31",{"name":48,"class":49},{"id":218,"slug":219,"hasResults":11,"nctId":220,"briefTitle":221,"officialTitle":221,"acronym":4,"eligibilityCriteria":222,"healthyVolunteers":11,"sex":16,"minAge":223,"maxAge":197,"enrollmentInfo":224,"targetDuration":4,"studyType":22,"phases":226,"briefSummary":227,"conditions":228,"keywords":230,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":235,"lastUpdatePostDateStruct":236,"startDateStruct":238,"completionDateStruct":240,"leadSponsor":242,"locationsCount":50},"100522005","mindfulness-intervention-for-college-students-with-adhd-100522005","NCT06076967","Mindfulness Intervention for College Students With ADHD","Inclusion Criteria:\n\n* First-semester college student with ADHD\n* Age 17-25\n* Must meet criteria for ADHD\n* No major medical problems\n\nExclusion Criteria:\n\n* Severe depression\n* Mania\n* Ongoing substance abuse\n* Personality disorder that may interfere with group delivery\n* Psychotic symptoms\n* Recent history of trauma\n* Unstable dosage of psychotropic medication","17 Years",{"count":225,"type":21},100,[24],"Attention-deficit\u002Fhyperactivity disorder (ADHD) is a neurodevelopmental disorder that commonly persists into adulthood and is associated with significant life impairments. The current study evaluates the feasibility, acceptability, and preliminary efficacy of a group-based mindfulness intervention for first-year college students with ADHD. If found to be feasible, acceptable, and efficacious, subsequent research will examine its impact on a larger scale to have a broader public health impact for college students with ADHD.",[229],"Attention Deficit Hyperactivity Disorder",[231,232,233,234],"ADHD","Mindfulness","College students","Emerging adults","2024-08-09",{"date":237,"type":42},"2024-08-12",{"date":239,"type":42},"2023-09-15",{"date":241,"type":21},"2026-07-31",{"name":48,"class":49},{"id":244,"slug":245,"hasResults":11,"nctId":246,"briefTitle":247,"officialTitle":248,"acronym":249,"eligibilityCriteria":250,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":251,"targetDuration":4,"studyType":22,"phases":253,"briefSummary":254,"conditions":255,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":260,"lastUpdatePostDateStruct":261,"startDateStruct":263,"completionDateStruct":265,"leadSponsor":267,"locationsCount":268},"100502335","enhancing-sleep-quality-for-nursing-home-residents-with-dementia---r33-phase-100502335","NCT05820919","Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase","Enhancing Sleep Quality for Nursing Home Residents With Dementia: Pragmatic Trial of an Evidence-Based Frontline Huddling Program","40Winks","Inclusion Criteria:\n\n* Nursing home residents aged \\>=50 years with an Alzheimer disease or related dementia (ADRD) diagnosis, identified by nursing home staff participating in frontline LOCK sleep huddles as having sleep problems\n\nExclusion Criteria:\n\n* Residents with a high risk of OSA who are not being treated for OSA because actigraph measurements are inaccurate in that population.\n* Residents who have a persistent bilateral resting tremor or paralysis in both arms (a subset of persons with Parkinson's disease and related significant tremor-causing diagnoses), due to actigraph measurement inaccuracies",{"count":252,"type":21},456,[24],"This study seeks to improve clinical outcomes for an important, growing, and vulnerable population-nursing home residents with Alzheimer's disease or related dementias-by testing an evidence-based intervention to improve these residents' sleep. It will also examine the implementation and sustainment of this intervention.",[256,257,258,259],"Alzheimer Disease","Dementia","Sleep Disorder","Sleep Disturbance","2024-03-11",{"date":262,"type":42},"2024-03-12",{"date":264,"type":42},"2023-09-07",{"date":266,"type":21},"2027-05-29",{"name":48,"class":49},3,{"id":270,"slug":271,"hasResults":11,"nctId":272,"briefTitle":273,"officialTitle":273,"acronym":4,"eligibilityCriteria":274,"healthyVolunteers":59,"sex":16,"minAge":60,"maxAge":275,"enrollmentInfo":276,"targetDuration":4,"studyType":22,"phases":278,"briefSummary":279,"conditions":280,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":83},"100527164","the-influence-of-aerobic-exercise-on-consolidation-of-fear-extinction-learning-in-ptsd-100527164","NCT06144203","The Influence of Aerobic Exercise on Consolidation of Fear Extinction Learning in PTSD","Inclusion Criteria for PTSD:\n\n* male or female sex\n* right-handed\n* age 18-64\n* a current diagnosis of PTSD where the index event involves interpersonal violence exposure (e.g., physical\u002Fsexual assault).\n\nInclusion criteria for the trauma-exposed (without PTSD) control participants includes:\n\n* male or female sex\n* right-handed\n* age 18-64\n* interpersonal violence exposure (e.g., physical\u002Fsexual assault).\n\nExclusion Criteria for all participants:\n\n* current substance use disorder (other than alcohol, nicotine, or cannabis)\n* acute suicidality\n* history of bipolar\u002Fpsychotic disorder\n* changes to or addition of psychiatric medication in the past 4 weeks (6 weeks for fluoxetine)\n* medications that effect neurovascular properties upon which BOLD fMRI capitalizes (e.g., water pills)\n* history of neurological disorders or disease (e.g., traumatic brain injury, epilepsy, seizures)\n* loss of consciousness \\> 10 minutes\n* intellectual disabilities (IQ\\\u003C70)\n* developmental disorders\n* MRI contraindication (e.g., internal ferromagnetic objects such as electronic devices, surgical implants, shrapnel; see phone screen)\n* claustrophobia or the inability to lie still in a confined space\n* physical disabilities that prohibit task performance (e.g., blindness or deafness)\n* positive pregnancy test\n* cochlear implant\n* an implanted neurostimulator\n* physical disabilities that prohibit task performance (e.g., blindness or deafness)\n* vulnerable populations (i.e., pregnant women, individuals appearing to lack consent capacity, prisoners, individuals unable to read consent materials, individuals in a relationship with study researchers (e.g., friends, family members, significant others)\n* having a history of chest pain during physical activity\n* having a bone, joint, cardiac, or other medical condition that a doctor has said may be worsened by physical activity\n* having asthma\n* responding 'Yes' to any of the seven questions on the Physical Activity Readiness Questionnaire (PAR-Q - administered as part of the Exercise Safety Questions of the phone screen), indicating it is unsafe for the individual to engage in aerobic exercise without physician approval (i.e., potential participant would be eligible to participate if they indicated 'Yes' to one or more of the PAR-Q items provided they obtain a doctor's note indicating it is safe for them to participate in the study)\n* Percutaneous Coronary Intervention or acute myocardial infarction in the last 6 weeks\n* unstable arrhythmias\u002Fimplanted cardiac defibrillator shocks in the last 3 months\n* any other condition that the PI believes might put the participant at risk.\n* Additionally, due to their effects on image quality, interested individuals with the following may be ineligible to participate per PI's judgement: nonremovable dental implants (e.g., braces or upper permanent retainers) as these will distort the MRI images we collect (note: filings, crowns, and silver or gold teeth are okay); any other condition, medication, or implant that the PI believes would degrade image quality or render data unusable","64 Years",{"count":277,"type":21},120,[24],"This study aims to test whether aerobic exercise performed after fear extinction learning improves cognitive, physiological, and neural indices of extinction recall in a sample of trauma-exposed men and women with and without posttraumatic stress disorder (PTSD). Participants will complete a clinical intake visit (Day 0), followed by a three-day fear conditioning (day 1), fear extinction + activity (day 2), and fear extinction recall (day 3) protocol.",[281],"PTSD","2024-02-13",{"date":284,"type":42},"2024-02-15",{"date":286,"type":42},"2024-01-29",{"date":288,"type":21},"2029-03",{"name":48,"class":49},""]