[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Barcelona\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":532},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,16,0,[8,48,78,103,132,153,181,212,244,283,326,366,398,438,471,504],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100616372","effect-of-probe-material-on-peri-implant-probing-100616372",false,"NCT07304752","Effect of Probe Material on Peri-implant Probing","Effect of Probe Material (Metallic vs. Plastic) on Peri-implant Probing: a Randomized Clinical Trial.","METPLA-PP","Inclusion Criteria:\n\n* Adults (≥18 years)\n* Presence of at least one single-unit bone-level implant rehabilitated with a screw-retained prosthesis directly connected to the implant (no intermediate abutment)\n* Implant in function for at least 1 year after prosthetic loading\n* No pathological bone loss on periapical radiograph (distance from the most coronal rough surface of the implant to the bone crest \\\u003C 3 mm)\n* Ability to understand and sign informed consent\n* Peri-implant health or mucositis, defined according to the 2017 World Workshop criteria:\n* Health: no clinical signs of inflammation, lack of profuse (line or drop) bleeding on probing, no increase in probing depth compared to previous records, and no progressive bone loss beyond initial remodeling (\\\u003C2 mm). In the absence of previous radiographs, radiographic bone level \\\u003C3 mm without bleeding and\u002For suppuration on probing.\n* Mucositis: presence of bleeding and\u002For suppuration on probing, no increase in probing depth compared to previous records, and no bone loss beyond initial remodeling (\\\u003C2 mm). In the absence of previous radiographs, radiographic bone level \\\u003C3 mm with bleeding and\u002For suppuration on probing.\n\nExclusion Criteria:\n\n* Cement-retained restorations or prostheses that cannot be removed\n* Systemic antibiotic or anti-inflammatory treatment within the previous 3 months\n* Pregnancy or lactation\n* Peri-implant treatment within the previous 3 months\n* Participation in another clinical trial within the last 30 days","ALL","18 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","Evaluate whether the type of probe (plastic vs. metallic) modifies the accuracy of peri-implant probing in single-unit implants, by comparing the probing depth recorded with the prosthesis in place versus without the prosthesis (ΔPD, mm). Secondarily, explore the influence of prosthetic design and implant position on probing values and on other clinical and radiographic parameters.",[27,28],"Peri-implant Health","Peri-implant Mucositis",[30,31,32,33,34],"Visual Analogue Scale","Peri-implant probing","Probing depth","Emergency profile","Dental implant","RECRUITING","2026-06-21",{"date":38,"type":39},"2026-06-24","ACTUAL",{"date":41,"type":39},"2026-01-01",{"date":43,"type":21},"2026-10",{"name":45,"class":46},"University of Barcelona","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":4},"100641806","knowledge-and-attitudes-about-advanced-maxillofacial-imaging-in-dental-professionals-100641806","NCT07651969","Knowledge and Attitudes About Advanced Maxillofacial Imaging in Dental Professionals","Knowledge and Attitudes About Advanced Maxillofacial Imaging (CBCT, TC, RM, PET\u002FTC y SPECT\u002FTC) in Dental Professionals","KAAMI","Inclusion Criteria:\n\nGeneral dentists, dentists with postgraduate training, oral and maxillofacial surgeons, undergraduate dental students, or postgraduate dental students.\n\nAbility to read and understand the questionnaire language. Willingness to participate and provide informed consent. Completion of the study questionnaire.\n\nExclusion Criteria:\n\nRefusal or inability to provide informed consent. Incomplete or partially completed questionnaires. Duplicate questionnaire submissions.",true,{"count":58,"type":21},220,"OBSERVATIONAL","Introduction:\n\nAdvanced maxillofacial imaging techniques, such as CBCT, CT, MRI, and hybrid modalities (PET\u002FCT and SPECT\u002FCT), have transformed diagnosis and treatment planning in dentistry. However, their increasing availability poses challenges related to the appropriate indication, interpretation, and application of radiation protection principles. Previous studies suggest variability in the level of knowledge and attitudes of dental professionals, which can impact the quality of care and patient safety.\n\nObjective:\n\nTo evaluate and compare the level of knowledge and attitudes regarding advanced maxillofacial imaging techniques among general dentists, dentists with postgraduate training, undergraduate\u002Fmaster's students in dentistry, and maxillofacial surgeons.\n\nMethodology: A cross-sectional study will be conducted using a structured questionnaire administered to general dentists, specialists, and students. A non-probability convenience sampling method will be used, with an estimated sample size of 220 participants. Statistical analysis will be performed using SPSS (version 31.0.1.0), establishing a significance level of p \\\u003C 0.05. A descriptive analysis of the variables will be carried out, expressing qualitative variables as frequencies and percentages, and quantitative variables as mean and standard deviation or median and range, depending on their distribution, which will be assessed using normality tests.\n\nFor bivariate analysis, ANOVA or Kruskal-Wallis tests will be used to compare the level of knowledge, attitudes, and confidence levels between groups, according to the data distribution, with post-hoc analysis in case of significant differences. Ordinal variables, such as the frequency of test requests, will be analyzed using chi-square tests.\n\nAssociations between variables will also be explored using Spearman's rank correlation coefficient, Student's t-test, or Mann-Whitney U test, and chi-square tests, depending on the nature of the data.\n\nExpected conclusion:\n\nThis study will allow us to identify differences in knowledge and attitudes between groups, as well as detect training needs, contributing to optimizing clinical practice and radiological safety in dentistry.",[62],"Knowledge",[64,65,66,67,68],"Cone-Beam Computed Tomography (CBCT)","Dental Radiology","Dental Education","Radiation Protection","PET\u002FCT","NOT_YET_RECRUITING","2026-06-14",{"date":72,"type":39},"2026-06-16",{"date":74,"type":21},"2026-06-15",{"date":76,"type":21},"2026-11-15",{"name":45,"class":46},{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":98,"startDateStruct":99,"completionDateStruct":100,"leadSponsor":102,"locationsCount":4},"100641960","phase-4-sonic-toothbrush-versus-an-oscillating-rotating-toothbrush-on-plaque-control-and-gingival-health-100641960","NCT07651982","Sonic Toothbrush Versus an Oscillating-rotating Toothbrush on Plaque Control and Gingival Health","A Randomized Crossover Clinical Trial Comparing a Sonic Toothbrush Versus an Oscillating-rotating Toothbrush on Plaque Control and Gingival Health","SONICOR","Inclusion criteria Adults aged 18 years or older. Able to perform daily oral hygiene independently. Presence of at least 20 natural teeth and\u002For implant-supported restorations. Patients attending the Master of Oral Medicine, Oral Surgery and Oral Implantology clinics at the Hospital Odontològic Universitat de Barcelona (HOUB).\n\nWilling and able to comply with study procedures and follow-up visits. Provision of written informed consent.\n\nExclusion Criteria:\n\nModerate or severe periodontitis requiring immediate treatment. Fixed orthodontic appliances. Use of systemic antibiotics or antiseptic mouthwashes (e.g., chlorhexidine) within 4 weeks prior to enrollment.\n\nPregnancy or breastfeeding. Participants unable to cooperate with study procedures due to psychomotor dysfunction or behavioral disorders.",{"count":87,"type":21},24,[89],"PHASE4","Objective:To evaluate the usefulness of a sonic toothbrush compared to an electric toothbrush for plaque removal and improving gingival health.Patients:Patients over 18 years of age who attend the Master's Degree in Medicine, Surgery and Oral Implantology of the HOUB or other clinical activities of the group cooperating with the study, who comply with the follow-up, and sign the informed consent.Material and method:A randomized clinical trial will be conducted.",[92,93],"Plaque Control","Gingival Health",[95,96,97],"sonic","toothbrush","oscillating",{"date":72,"type":39},{"date":74,"type":21},{"date":101,"type":21},"2026-12-15",{"name":45,"class":46},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":118,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":47},"100638497","comparison-of-anesthetic-efficacy-and-safety-between-inferior-alveolar-nerve-block-and-the-infiltrative-technique-for-the-treatment-of-peri-implant-diseases-in-posterior-mandibular-implants-100638497","NCT07590037","Comparison of Anesthetic Efficacy and Safety Between Inferior Alveolar Nerve Block and the Infiltrative Technique for the Treatment of Peri-implant Diseases in Posterior Mandibular Implants","Comparison of Anesthetic Efficacy and Safety Between Inferior Alveolar Nerve Block and the Infiltrative Technique for the Treatment of Peri-implant Diseases in Posterior Mandibular Implants: A Triple-blind Randomized Clinical Trial","Inclusion Criteria:\n\n* Adult patients (≥18 years) requiring surgical treatment of peri-implantitis in the posterior mandibular sector.\n* Patients without relevant systemic disease (ASA II or lower).\n* Sufficient intellectual capacity to understand the study and informed consent and to complete the questionnaires adequately.\n\nExclusion Criteria:\n\n* Pregnant patients.\n* Patients with allergy or hypersensitivity to articaine or epinephrine.\n* Patients with uncontrolled systemic diseases.\n* Patients with coagulation disorders or medication that alters coagulation.\n* Patients who may be able to recognize the anesthetic technique used, such as dentists.\n* Drugs or systemic diseases (ASA III or higher) that contraindicate surgical intervention or the use of anesthetics and\u002For vasoconstrictors.\n* Patients with relative or absolute contraindication to conventional analgesic or anti-inflammatory regimens.",{"count":111,"type":21},30,[24],"This triple-blind randomized clinical trial aims to compare the anesthetic efficacy and safety of two local anesthesia techniques for the surgical treatment of peri-implantitis in posterior mandibular implants: inferior alveolar nerve block (IANB) and infiltrative anesthesia with 4% articaine and epinephrine 1:100,000.\n\nPeri-implantitis is an inflammatory disease affecting the tissues around dental implants, characterized by progressive bone loss and clinical signs of inflammation. When non-surgical therapy is insufficient, surgical treatment is required, usually involving flap elevation, debridement of granulation tissue, implant surface decontamination, and, depending on the defect, resective, regenerative, or combined surgery.\n\nEffective local anesthesia is essential in these procedures, especially in the posterior mandible, where dense bone may limit anesthetic diffusion. IANB is the conventional technique for achieving profound mandibular anesthesia, but it may fail due to anatomical variations, accessory innervation, or technical difficulty. Infiltrative anesthesia has been proposed as an alternative, particularly with articaine because of its high diffusion capacity, although its predictability in complex mandibular surgery remains uncertain.\n\nThe main objective is to compare the efficacy of IANB and infiltrative anesthesia, measured by the need for re-anesthesia during surgery. Secondary objectives include assessing safety, intraoperative discomfort, postoperative pain, duration of anesthesia, patient satisfaction, and adverse events.\n\nAdult patients requiring surgical treatment for peri-implantitis in posterior mandibular implants at the Dental Hospital of the University of Barcelona will be included. Eligible participants must be ≥18 years old, medically fit for surgery, and able to understand the study and complete the questionnaires. Exclusion criteria include pregnancy, allergy to articaine or epinephrine, uncontrolled systemic disease, coagulation disorders or anticoagulant medication, ASA III or higher status, and contraindications to conventional analgesic or anti-inflammatory medication.\n\nParticipants will be randomly assigned to either the IANB group or the infiltrative anesthesia group. Randomization will be performed using a computer-generated sequence placed in opaque, sequentially numbered envelopes. The patient, surgeon, outcome assessor, and statistician will remain blinded to group allocation.\n\nThe study includes three visits. At the first visit, eligibility will be assessed and informed consent obtained. At the second visit, surgery will be performed after the assigned anesthetic technique. Patients will record pain using visual analogue scales at injection, during surgery, 2 h, 6 h, 12 h, 24 h, and daily until day 7, as well as rescue medication use and sick leave. At the third visit, 7-9 days after surgery, postoperative healing, complications, adverse events, pain diary, and patient satisfaction will be assessed.\n\nThe primary outcome is anesthetic efficacy, defined as absence of need for re-anesthesia. Secondary variables include demographic factors, systemic disease, medication, smoking, dental anxiety, type and duration of surgery, surgeon experience, number and position of implants, intraoperative and postoperative pain, duration of anesthesia, adverse events, complications, and patient-reported experience measures.\n\nData will be analyzed using Stata\u002FIC 15.1. Quantitative variables will be described using means and standard deviations or medians and interquartile ranges, depending on normality. Qualitative variables will be presented as frequencies and percentages. Group comparisons will use appropriate statistical tests, with significance set at p \\\u003C 0.05.\n\nAs a pilot exploratory trial, the study will include 30 patients, 15 per group. Its aim is to assess feasibility, estimate preliminary event rates, and generate data for future confirmatory trials. The study will follow the Declaration of Helsinki and applicable data protection regulations. Participation will be voluntary, anonymous, and based on written informed consent.",[115,116,117],"Local Anesthesia","Dental Implants","Periimplantitis",[119,120,121,122,123],"dental implants","articaine","periimplantitis","block nerve","local anesthesia","2026-05-19",{"date":126,"type":39},"2026-05-22",{"date":128,"type":21},"2026-09",{"date":130,"type":21},"2027-12",{"name":45,"class":46},{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":4,"eligibilityCriteria":138,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":139,"targetDuration":4,"studyType":22,"phases":141,"briefSummary":142,"conditions":143,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":47},"100640339","does-hyaluronic-acid-help-relieve-dry-mouth-100640339","NCT07594184","Does Hyaluronic Acid Help Relieve Dry Mouth?","Efficacy of Submucosal Hyaluronic Acid Infiltration in Improving the Sensation of Dry Mouth in Patients With Xerostomia: A Double-Blind Randomized Clinical Trial.","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Patients reporting symptoms compatible with xerostomia for at least one year\n* Patients who agree to cooperate in the study, comply with the follow-up plan, and sign the informed consent\n\nExclusion Criteria:\n\n* Underage patients\n* Pregnant patients\n* Patients on antiplatelet or anticoagulant therapy\n* Patients with a history of adverse reactions to hyaluronic acid infiltration\n* Patients with active infectious diseases in the oral cavity\n* Immunocompromised patients\n* Patients with other active diseases affecting the oral mucosa\n* Patients with uncontrolled autoimmune diseases\n* Patients allergic to lidocaine and\u002For mepivacaine\n* Patients undergoing active chemotherapy and\u002For radiotherapy for head and neck\n* Non-cooperative patients (e.g., psychomotor dysfunctions and behavioral disorders)",{"count":140,"type":21},40,[24],"The goal of this clinical trial is to learn if hyaluronic acid infiltration helps relieve dry mouth symptoms in adults with xerostomia. It will also assess the safety and duration of the treatment's effects.\n\nThe main questions it aims to answer are:\n\n1. Does hyaluronic acid improve the sensation of dry mouth?\n2. What side effects may occur after treatment?\n3. How long does the effect of the treatment last?\n4. Are there changes in salivary flow and pH after treatment?\n\nResearchers will compare hyaluronic acid to a placebo (a look-alike substance with no active ingredient) to determine its effectiveness.\n\nParticipants will:\n\nReceive submucosal injection of either hyaluronic acid or placebo Visit the clinic once a month for 6 months for follow-up evaluations Not be required to perform any tasks at home",[144],"Xerostomia","2026-05-13",{"date":147,"type":39},"2026-05-18",{"date":149,"type":39},"2025-11-11",{"date":151,"type":21},"2026-12",{"name":45,"class":46},{"id":154,"slug":155,"hasResults":11,"nctId":156,"briefTitle":157,"officialTitle":157,"acronym":158,"eligibilityCriteria":159,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":160,"enrollmentInfo":161,"targetDuration":4,"studyType":22,"phases":163,"briefSummary":164,"conditions":165,"keywords":167,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":47},"100528867","improving-the-treatment-of-anorexia-nervosa-in-children-through-virtual-reality-body-exposure-100528867","NCT06166355","Improving the Treatment of Anorexia Nervosa in Children Through Virtual Reality Body Exposure","EOAN-VR-ABM","Inclusion Criteria:\n\n* Patients with a primary diagnosis of anorexia nervosa (DSM-V)\n* Patients below 14 years old\n* Patients with BMI \\\u003C18.5\n* Subsyndromal patients will also be included\n\nExclusion Criteria:\n\n* Visual deficits\n* Epilepsy or neuroleptic medication\n* Psychotic disorder\n* Bipolar disorder\n* Medical complications\n* Pregnancy\n* Clinical cardiac arrhythmia","14 Years",{"count":162,"type":21},108,[24],"The age of onset of anorexia nervosa has been progressively decreasing in recent years. Also, the prevalence rates of childhood anorexia in many countries have grown significantly. This increase was already observed before the COVID-19 pandemic, but the confinements and the stress derived from them have caused this increase to accelerate. As in adolescent and adult patients, in childhood anorexia some of the core signs and symptoms are an extreme fear of gaining weight and avoidance of food. The consequences of the early-onset of anorexia can be very important since the maturation of the organism is more incomplete in children than in adolescents. Weight loss can have very severe consequences, since in children the percentage of body fat is lower. On the other hand, hormonal disorders derived from food deprivation also have very severe consequences for the development of different organs. General physical development and growth can be affected, with consequences such as not being able to reach normal height. The research carried out to date on the efficacy of treatments for childhood anorexia is very scarce. There are no specific treatment strategies or settings for children with anorexia, and little research has been done to tailor treatment for younger patients. Given the need to explore new treatments for anorexia nervosa specifically aimed at children, the objective of this project is to develop a program to carry out exposure to one's own body through virtual reality, gradually, with progressive increases in size until achieving a healthy weight. In the virtual exposure, patients will observe the image of an avatar in a mirror for the time necessary in each session to produce the reduction of the anxiety response. The avatars that will be developed for this purpose will have a physical constitution corresponding to children under 14 years of age, and physical proportions equivalent to those of each patient. The positive results obtained with a previous version of this treatment originally developed for adolescents and adults suggest that its adaptation to children can open new ways for exploring effective treatments for childhood anorexia.",[166],"Anorexia Nervosa",[168,169,170,171,172],"Attentional Bias","Virtual Reality","Eye-Tracking","Body exposure procedure","Attentional bias modification training","2026-05-04",{"date":175,"type":39},"2026-05-08",{"date":177,"type":39},"2024-07-01",{"date":179,"type":21},"2026-12-30",{"name":45,"class":46},{"id":182,"slug":183,"hasResults":11,"nctId":184,"briefTitle":185,"officialTitle":185,"acronym":4,"eligibilityCriteria":186,"healthyVolunteers":11,"sex":187,"minAge":188,"maxAge":189,"enrollmentInfo":190,"targetDuration":4,"studyType":22,"phases":192,"briefSummary":193,"conditions":194,"keywords":198,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":205,"startDateStruct":207,"completionDateStruct":209,"leadSponsor":211,"locationsCount":47},"100605703","nursing-interventions-to-enhance-positive-mental-health-and-self-care-in-women-during-the-climacteric-100605703","NCT07165964","Nursing Interventions to Enhance Positive Mental Health and Self Care in Women During the Climacteric","Inclusion Criteria:\n\n* Women aged 42-58 years attending the participating ASSIR centers.\n* Clinically identified symptoms of climacteric during routine consultation.\n\nExclusion Criteria:\n\n* Cognitive or learning impairments preventing comprehension of study procedures.\n* Physical, emotional, or intellectual limitations hindering completion of study instruments or participation in the intervention.\n* Current treatment for hormone dependent cancer.\n* Use of an intrauterine device or ongoing hormonal contraceptives.\n* Other medical causes of secondary menopause.","FEMALE","42 Years","58 Years",{"count":191,"type":21},250,[24],"This study will test whether a nursing program using podcasts and videos can help women feel better and take better care of themselves during the climacteric (the stage leading up to and following menopause). Women between 42 and 58 years old who attend public sexual and reproductive health clinics in the Metropolitan South Health Region of Barcelona (Sant Boi, Sant Feliu, and Cornellà) will be invited to participate.\n\nParticipants will be randomly assigned to one of two groups:\n\nIntervention Group: will receive access to podcasts and videos offering practical advice and strategies to improve emotional well-being and self-care.\n\nControl Group: will receive standard care. All participants will complete questionnaires before and after the program to assess symptoms, mental health, and satisfaction with self-care. Statistical methods will be used to compare the results between both groups and determine whether the program produces a significant difference.\n\nThe aim of the study is to demonstrate that this digital nursing intervention is effective and could be implemented more broadly in healthcare settings.",[195,196,197],"Climacteric Symptoms","Climactericum","Self Care",[199,200,201,202,203],"climateric symptoms","women","climactericum","self care","positive mental health","2026-02-04",{"date":206,"type":39},"2026-02-05",{"date":208,"type":39},"2025-07-31",{"date":210,"type":21},"2026-09-30",{"name":45,"class":46},{"id":213,"slug":214,"hasResults":11,"nctId":215,"briefTitle":216,"officialTitle":217,"acronym":218,"eligibilityCriteria":219,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":220,"enrollmentInfo":221,"targetDuration":4,"studyType":22,"phases":223,"briefSummary":224,"conditions":225,"keywords":229,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":243,"locationsCount":47},"100508349","immersive-training-on-metacognitive-capacities-of-young-people-100508349","NCT05899257","Immersive Training on Metacognitive Capacities of Young People","Effects of Brief Immersive Training on the Metacognitive Capacities and Self-knowledge of Young People","VRtraining","Inclusion Criteria:\n\n* Volunteers between 18 and 29 years of age\n\nExclusion Criteria:\n\n* Diagnosis of a mental disorder (current or in the last year)\n* Current psychological or psychiatric treatment\n* Suicidal ideation\n* Insufficient level of competence to communicate in Spanish or English","29 Years",{"count":222,"type":21},55,[24],"Metacognitive abilities and self-knowledge are necessary for psychological maturation and good mental functioning of individuals. It is generally agreed that an adequate representation of oneself and others is essential to establish functional interpersonal relationships. These metacognitive abilities are not adequately developed in patients with various mental health problems, such as personality disorders, eating disorders, psychosis, and depression, and are associated with the severity of the pathology.\n\nSelf-awareness is a central element that begins to consolidate during adolescence. For that reason, the investigators aim to evaluate the effects of immersive training on the metacognitive abilities and self-knowledge of young people. Based on the repertory grid technique (RGT), our research team has developed a brief immersive training to enhance metacognitive abilities. This intervention facilitates the exploration of personal identity in a safe environment. Specifically, it is an immersion in the person's own world of meanings using Virtual Reality (VR), with the Explore Your Meanings (EYME) tool, a technological platform created to help mental health professionals to enhance the personal development and therapeutic change of their clients. Expected results include an increase in participants' self-concept clarity, metacognition, and reflective function as well as a deeper knowledge about their relationship with various aspects of self-knowledge and self-esteem.",[226,227,228],"Self","Self-Perception","Self Esteem",[230,231,232,233,234,235,236],"mentalization","self-knowledge","reflective function","virtual reality","self-identity","mental map","sense of identity","2026-01-30",{"date":239,"type":39},"2026-02-03",{"date":241,"type":39},"2023-05-01",{"date":151,"type":21},{"name":45,"class":46},{"id":245,"slug":246,"hasResults":11,"nctId":247,"briefTitle":248,"officialTitle":249,"acronym":250,"eligibilityCriteria":251,"healthyVolunteers":11,"sex":17,"minAge":252,"maxAge":220,"enrollmentInfo":253,"targetDuration":4,"studyType":22,"phases":255,"briefSummary":256,"conditions":257,"keywords":260,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":274,"lastUpdatePostDateStruct":275,"startDateStruct":277,"completionDateStruct":279,"leadSponsor":281,"locationsCount":282},"100545614","identity-based-transdiagnostic-therapy-for-young-people-with-anxiety-and-depression-100545614","NCT06384196","Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression","Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression: Engagement, Efficacy, and Predictors of Outcome","IBTTYOUNG","Inclusion Criteria:\n\n• Participants with symptoms of depression and\u002For anxiety as their primary complaint.\n\nExclusion Criteria:\n\n* Participants with post-traumatic stress, bipolar and substance use disorders, psychotic symptoms, organic brain dysfunction, marked suicidal ideation and\u002For intellectual disability.\n* Participants receiving psychological treatment, unless it is suspended at the time of inclusion in the study itself in agreement with their therapist.\n* Participants for whom the use of virtual reality may pose a risk, even a minor risk (epilepsia, acute otorhinolaryngological processes or recent interventions, severe cardiovascular disease, unstable hypertension, and pregnancy).\n* Participants with substantial visual, hearing, and cognitive deficits.\n* Participants who do not have enough competence to communicate in Spanish or Catalan.","16 Years",{"count":254,"type":21},138,[24],"Depression and anxiety are the most prevalent mental disorders among both the general population and young adults, and transdiagnostic treatments for these patients are mostly based on cognitive-behavioral therapy (CBT). Based on common (transdiagnostic) principles of treatment (e.g., emotional exposure), these approaches have proliferated and demonstrated their efficacy in comparison to disorder-specific treatments. Although there are a few transdiagnostic approaches for children and adolescents, it was not possible to not find anyone targeting young people. For this reason, the investigators proposed the Identity-Based Transdiagnostic Therapy (IBTT) as a new treatment modality ideally created to address the challenge of improving the outcomes of psychotherapy for young adults with anxiety and\u002For depression. The IBTT is a psychological treatment for emotional disorders specifically designed for the youths in terms of their attitudes to treatment (attractiveness, engagement), and highly personalized to their construal of self and others. This project will allow testing the hypothesis that a novel brief psychotherapeutic intervention, IBTT, will be more efficacious in the treatment of the anxiety and\u002For depression of young adults than the well-established CBT-based Unified Protocol.",[258,259],"Depression","Anxiety",[261,169,262,263,264,265,266,267,268,269,270,271,272,273],"Young Adult","Self-identity","Sense of identity","Psychological Conflict","Self-concept","Self-assessment","Metacognitive Awareness","Cognitive Reflection","Personal Satisfaction","Patient Satisfaction","Psychological Well-Being","Therapeutic Alliance","Treatment Outcome","2026-01-22",{"date":276,"type":39},"2026-01-26",{"date":278,"type":39},"2025-05-02",{"date":280,"type":21},"2026-11-02",{"name":45,"class":46},2,{"id":284,"slug":285,"hasResults":11,"nctId":286,"briefTitle":287,"officialTitle":288,"acronym":289,"eligibilityCriteria":290,"healthyVolunteers":11,"sex":17,"minAge":291,"maxAge":292,"enrollmentInfo":293,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":295,"conditions":296,"keywords":299,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":318,"lastUpdatePostDateStruct":319,"startDateStruct":321,"completionDateStruct":323,"leadSponsor":325,"locationsCount":47},"100617127","clinical-and-radiological-evaluation-of-dental-autotransplantation-in-the-anterior-region-in-young-patients-100617127","NCT07314580","Clinical and Radiological Evaluation of Dental Autotransplantation in the Anterior Region in Young Patients","Clinical, Radiographic, Functional and Psychosocial Evaluation of Premolar Autotransplantation to the Anterior Maxillary Region in Young Patients: An Ambispective Observational Study","YATA","Inclusion Criteria:\n\n* Patients aged 7 to 15 years.\n* ASA I classification.\n* Loss or indication for extraction of a maxillary anterior tooth (teeth 12, 11, 21, or 22) due to trauma, resorption, or restorative reasons.\n* Availability of a donor first or second premolar with root development between one-half and complete root length.\n* Ability to complete at least 2 years of follow-up.\n* Parent\u002Fguardian consent and minor assent obtained for prospective cases.\n\nExclusion Criteria:\n\n* Patients older than 15 years.\n* Severe systemic disease.\n* Inability or unwillingness to attend scheduled follow-up visits.\n* Lack of a suitable donor premolar.","7 Years","15 Years",{"count":294,"type":21},50,"This study aims to evaluate the clinical, radiographic, functional, and patient-reported outcomes of premolar autotransplantation used to replace anterior maxillary teeth in young patients. The study has an ambispective observational design, including a retrospective cohort (patients treated between December 2019 and December 2025) and a prospective cohort (patients enrolled until December 2028).\n\nParticipants aged 7 to 15 years who received or will receive premolar autotransplantation to replace an anterior tooth will be followed clinically and radiographically for up to 5 years. Outcomes include tooth survival, periodontal and pulpal healing, root development, complications, orthodontic interactions, restorative needs, and patient satisfaction. The study seeks to identify prognostic factors and long-term success indicators for dental autotransplantation in growing patients.",[297,298],"Tooth Loss","Tooth Injury",[300,301,302,303,304,305,306,307,308,309,310,311,312,313,314,315,316,317],"autotransplantation","tooth autotransplant","premolar donor tooth","anterior maxilla","young patients","root development","CBCT","digital planning","guided surgery","orthodontics","periodontal healing","pulpal healing","traumatic tooth loss","avulsion injuries","trauma-related anterior tooth loss","Dental autotransplantation","Anterior maxillary tooth loss","tooth root development","2025-12-17",{"date":320,"type":39},"2026-01-02",{"date":322,"type":39},"2019-12-01",{"date":324,"type":21},"2029-12-31",{"name":45,"class":46},{"id":327,"slug":328,"hasResults":11,"nctId":329,"briefTitle":330,"officialTitle":331,"acronym":4,"eligibilityCriteria":332,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":333,"targetDuration":4,"studyType":22,"phases":335,"briefSummary":336,"conditions":337,"keywords":339,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":357,"lastUpdatePostDateStruct":358,"startDateStruct":360,"completionDateStruct":362,"leadSponsor":364,"locationsCount":365},"100552828","closed-blood-sampling-devices-in-the-adult-critically-ill-patient-100552828","NCT06478160","Closed-blood Sampling Devices in the Adult Critically Ill Patient","Effectiveness of Closed-blood Sampling Devices in the Adult Critically Ill Patient: Multicenter Randomized Clinical Trial","Inclusion Criteria:\n\n* Adult patients with an arterial catheter who agree to participate in the study, with a stay in the ICU of 24h and a minimum of 72h more with an arterial catheter\n\nNon-inclusion criteria: Therapeutic Limitation of Life Support, Jehovah's Witnesses.\n\nExclusion Criteria:\n\n* Patients with chronic renal failure\n* Patients with active gastrointestinal bleeding\n* Patients diagnosed with hematologic cancer\n* Women with menstruation at the time of admission\n* Pregnant women\n\nWithdrawal criteria: presence of active gastrointestinal bleeding during the study inclusion period.",{"count":334,"type":21},216,[24],"Based on the hypothesis that the strategy of using Closed-Blood Sampling Devices (CSBD, experimental group) compared to the usual practice (waste discard volume, control group), in critically ill adult patients, will decrease the amount of blood withdrawn for laboratory tests, we want to analyze the number of red blood cells (RBC) administered and arterial catheter-related adverse events (catheter-related bacteremia, catheter obstruction, CBSD malfunction, loss of arterial pressure waveform on the patient's bedside monitor) in both study groups, during ICU stay and up to a maximum of 21 days.",[338],"Acceptability of Health Care",[340,341,342,343,344,345,346,347,348,349,350,351,352,353,354,355,356],"anaemia","transfusion","diagnostic blood loss","phlebotomy","blood management","hospital-acquired anemia","iatrogenic anemia","sampling practices","blood conservation","blood sample collection","catheter-related infections","critical care","nursing","blood conservation devices","clinical trial","laboratory testing","blood chemistry tests","2025-11-06",{"date":359,"type":39},"2025-11-10",{"date":361,"type":39},"2024-11-11",{"date":363,"type":21},"2026-06-07",{"name":45,"class":46},3,{"id":367,"slug":368,"hasResults":11,"nctId":369,"briefTitle":370,"officialTitle":371,"acronym":372,"eligibilityCriteria":373,"healthyVolunteers":56,"sex":17,"minAge":374,"maxAge":4,"enrollmentInfo":375,"targetDuration":4,"studyType":22,"phases":377,"briefSummary":378,"conditions":379,"keywords":382,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":390,"lastUpdatePostDateStruct":391,"startDateStruct":393,"completionDateStruct":395,"leadSponsor":397,"locationsCount":47},"100601697","reframing-expectations-about-aging---physical-activity-and-inclusive-reappraisal-100601697","NCT07113860","Reframing Expectations About Aging - Physical Activity and Inclusive Reappraisal","Reframing Expectations About Aging - Physical Activity and Inclusive Reappraisal (RE-PAIR): Protocol of an Intervention Aiming to Promote Positive Views on Aging and Behavior Change in Older Couples","RE-PAIR","Inclusion criteria are:\n\n* living in the community in Barcelona or nearby areas;\n* both partners being aged ≥ 65 years;\n* speaking fluent Catalan or Spanish;\n* being married, having a partner with whom they co-habit, or having had a partner for at least one year and with whom they meet at least twice a week;\n* having access to a smartphone, tablet, laptop, or computer with internet;\n* both partners being willing to participate in the study and providing written informed consent.\n\nAlthough the use of a chronological age cut-off to define older people is inherently arbitrary, this study adopts the threshold of 65 years and older to establish inclusion criteria for participation. This decision reflects the increasing self-relevance of age-stereotypes and self-perceptions of aging in later life, particularly among the oldest age groups. Participants can either possess a device that can be connected to the internet or use the device of a family member, neighbor, or friend. Moreover, participants with low technology literacy can nonetheless take part in the study as during baseline assessment the research team will show them how to complete the online questionnaires. Moreover, the research team will be available via email and phone to answer participants' queries related to completion of the online questionnaires. Both retired and working people are eligible to take part in the study. People of any race can take part in the study. Couples of all sexual orientations are welcome to participate in the study.\n\nExclusion criteria are:\n\n* having a self-reported or clinically diagnosed neurodegenerative disorder, and\u002For an Adult Lifestyles and Function Interview Mini Mental State Examination (ALFI-MMSE) score of \\\u003C 15 out of 22, indicating mild cognitive impairment or dementia. The research team has considerable experience with the administration of the MMSE and will adjust scores for individuals with low cultural background;\n* currently having a clinical diagnosis of mental health disorder that significantly impacts on the daily functioning of the individual (i.e., a diagnosis that significantly impacts the participants ability to work, do house chores, and\u002For engage socially);\n* current substance use disorder (alcohol or drug abuse), or a history of substance abuse within the past five years that may interfere with study participation or adherence to the intervention;\n* having a physical condition or physical limitations that impair from starting a physical activity intervention consisting in walking between three to five times per week and to do some physical tasks such as stand up from and sit down on a chair and back scratch;\n* severe hearing impairment (deafness).\n\nPhysical limitations will be self-reported by participants via phone but also further objectively assessed by the researchers at baseline assessment. Individuals with neurodegenerative disorders will be excluded as it could be difficult for them to understand and participate in the psychoeducational sessions, and\u002For engage in brisk walking. Individuals with current severe mental health disorders and\u002For with substance abuse will be excluded as these groups are less likely to be compliant with intervention conditions. However, individuals with more common mental health disorders (i.e., depressive disorders and anxiety disorders) that are not severe enough to significantly impact the daily functioning of the individual will be allowed to take part in the study. Individuals with significant physical limitations will be excluded as they could put themselves at risk of falling while engaging in physical activity\u002Fwalking.","65 Years",{"count":376,"type":21},342,[24],"The goal of this clinical trial is to promote positive views on aging and walking in Spanish partners aged 65 years and over. The trial will comprise three arms. In the first arm, both partners will undertake the intervention together. In the second arm, only one of the two partners will undertake the intervention. In the third arm (control) none of the partners will undertake the intervention. Collection of quantitative data will make it possible to test the following hypotheses:\n\n1. Differently from arm three, those participants from arms one and two who undertake the intervention will experience changes in primary and secondary intervention outcomes between pre- and post-intervention and these changes will be maintained at follow-ups.\n2. Compared to delivering the intervention to only one partner, delivering it to both partners will lead to a greater and more lasting change in primary and secondary intervention outcomes.\n3. In the group where only one partner will undertake the intervention, their change in intervention outcomes is observed at least to a small extent in the other partner.\n\nQualitative data collected at the end of the intervention through interviews of ten couples from each of arms one and two will make it possible to test three additional research questions:\n\n1. How do participants in Group one engage with the intervention tasks, and to what extent do they undertake these tasks jointly as a couple?\n2. In what ways do participants in Group two involve their non-participating partner in the intervention activities?\n3. What changes do participants in Groups one and two report in their views of themselves and their aging, as well as in their perceptions of and interactions with their partner?\n\nParticipants will undertake a multicomponent intervention comprising:\n\n* Three in-person psychoeducational sessions aiming to promote positive views on aging, including positive self-perceptions of aging, and accurate facts about aging\n* Independent walking for 12 weeks Primary intervention outcomes are changes in participants' self-perceptions of aging and physical activity engagement. Secondary intervention outcomes are changes in ageism, subjective views of couple's joint aging, perceived age-related changes in one's partner, mood, physical fitness, and cognitive functioning.",[380,381],"Self-perceptions of Aging","Physical Activity",[383,384,385,386,387,388,389],"Physical activity","Walking","Self-Perceptions of Aging","Ageism","Subjective aging","couples","spouses","2025-08-14",{"date":392,"type":39},"2025-08-19",{"date":394,"type":39},"2025-07-28",{"date":396,"type":21},"2027-10",{"name":45,"class":46},{"id":399,"slug":400,"hasResults":11,"nctId":401,"briefTitle":402,"officialTitle":403,"acronym":404,"eligibilityCriteria":405,"healthyVolunteers":56,"sex":17,"minAge":406,"maxAge":407,"enrollmentInfo":408,"targetDuration":4,"studyType":22,"phases":410,"briefSummary":411,"conditions":412,"keywords":417,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":430,"lastUpdatePostDateStruct":431,"startDateStruct":433,"completionDateStruct":435,"leadSponsor":437,"locationsCount":47},"100525882","peanut-consumption-on-cognitive-weight-and-inflammation-100525882","NCT06127511","Peanut Consumption on Cognitive, Weight, and Inflammation","Peanut Consumption on Cognitive Performance, Weight Management, and Inflammation in Young Adolescents","PEANUTY","Inclusion Criteria:\n\nEligible participants will be young adolescents, boys and girls, aged between 10 and 12 years who attend regular primary schools in Barcelona. The schools will assist with the participant recruitment through the classes and after that, a total of one-hundred students will be randomly included in each group. In all cases, participation will be voluntary and informed consent will be obtained prior to the study.\n\nExclusion Criteria:\n\nThe exclusion criteria will be history of allergy or intolerance to peanuts, any medical conditions or dietary restrictions that would affect peanut consumption, being able to understand Spanish or Catalan, and use of antibiotics in the month prior to the study.","10 Years","12 Years",{"count":409,"type":21},200,[24],"A multi-school, two-arm parallel cluster-randomized controlled trial will be conducted in 200 healthy young adolescents from Barcelona (Spain) to evaluate the effect of peanut consumption on cognitive performance, weight management and inflammation. Schools willing to participate will be randomly assigned to either the intervention or the control group. After the recruitment, the participants will follow a peanut-free diet for two weeks. Both arms will receive a multidimensional educational intervention designed by the Gasol Foundation to promote healthy dietary habits based on Mediterranean diet recommendations, along with exercise performance, healthy sleeping habits and emotional knowledge. Half of the participants (intervention group) will consume 25 g of whole skin roasted peanuts as a daily snack to be incorporated into their diet for six months.",[413,414,415,416],"Cognitive Performance","Inflammation","Weight Change, Body","Adolescents",[418,419,420,421,422,423,424,425,426,427,428,429],"peanut","cognitive","inflammation","weight","adolescent","obesity","gut microbiota","healthy dietary","physical activity","sleeping","behaviour habits","Mediterranean diet","2025-03-31",{"date":432,"type":39},"2025-04-03",{"date":434,"type":39},"2024-01-29",{"date":436,"type":21},"2025-12-31",{"name":45,"class":46},{"id":439,"slug":440,"hasResults":11,"nctId":441,"briefTitle":442,"officialTitle":443,"acronym":444,"eligibilityCriteria":445,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":446,"targetDuration":4,"studyType":22,"phases":448,"briefSummary":449,"conditions":450,"keywords":454,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":463,"lastUpdatePostDateStruct":464,"startDateStruct":466,"completionDateStruct":468,"leadSponsor":470,"locationsCount":282},"100568283","effectiveness-of-a-multidisciplinary-treatment-for-patients-with-chronic-low-back-pain-100568283","NCT06679205","Effectiveness of a Multidisciplinary Treatment for Patients With Chronic Low Back Pain","Effectiveness of a Multidisciplinary Treatment for Patients With Chronic Low Back Pain (PAINDOC Protocol): Randomized, Parallel-group, Two-arm, Single-blind Clinical Trial (PAINDOC Project)","PAINDOC","Inclusion Criteria:\n\n* Patients over 18 years of age.\n* Patients with primary chronic low back pain (non-specific chronic low back pain) of axial predominance.\n* Experiencing pain at least 50% of the time over the last 6 months.\n* Average weekly pain intensity equal or greater than 4 out of 10 on a verbal numerical scale.\n* Be agreeable to receiving active, non-pharmacological and non-surgical treatment.\n\nExclusion Criteria:\n\n* Inflammatory low back pain.\n* History of cancer in the last 5 years.\n* Unexplained and unintentional weight loss of 10 Kg or more over the preceding 12-month period.\n* Lack of control of bowel and bladder function (cauda equina).\n* Difficulty in performing the sessions due to severe physical disability.\n* Diagnosis of severe mental illness (schizophrenia, major depression, bipolar disorder, etc.).\n* Strong prescription opioid or parenteral medication addiction disorders.\n* Technical-logistical problems (inability to attend treatment sessions or inability to fill out assessment questionnaires).\n* Problems in understanding the content of the sessions (language barrier, severe hearing loss or severe cognitive impairment).\n* Have sought compensation or entered into litigation in the preceding 12-month period.",{"count":447,"type":21},62,[24],"PAINDOC is a treatment program that includes 4 disciplines that, separately, have demonstrated their effectiveness in the treatment of chronic low back pain: education in pain neuroscience, therapeutic education (Empowered Relief®), psychotherapy based on cognitive-behavioral therapy and therapeutic exercise.\n\nThe primary objective of the study is to evaluate the effectiveness of the PAINDOC multidisciplinary treatment program in reducing pain intensity and improving quality of life in persons with chronic low back pain referred to the pain unit of the Hospital Clinic of Barcelona, compared to usual care treatment.\n\nAs secondary objectives, the present study aims to evaluate the effect of the PAINDOC program on:\n\n* The reduction of pain-related disability.\n* The reduction of pain catastrophizing.\n* The improvement in perceived social support.\n* The improvement in perceived autonomy (self-efficacy).\n* The reduction of analgesic, anti-inflammatory and adjuvant analgesic medication.\n\nThe main questions it aims to answer are:\n\n* Is the proposed multidisciplinary treatment effective in improving pain-related outcomes?\n* Is the proposed multidisciplinary treatment effective in reducing analgesic medication?\n\nParticipants will receive either usual care (pharmacological control) or the PAINDOC program, which consists of 7 multidisciplinary sessions within 2 months. There will be one therapeutic education session called Empowered Relief®, 2 pain neuroscience education sessions, one pain psychology session and 3 therapeutic education sessions. Besides, participants will be assessed using written questionnaires before treatment, at 3 months and at 6 months.\n\nResearchers will assess the effectiveness of the multidisciplinary treatment group comparing both groups to see if there is any difference in several pain-related outcomes.",[451,452,453],"Chronic Low-back Pain (cLBP)","Chronic Low-back Pain","Back Pain",[455,456,457,458,459,460,461,462],"chronic low-back pain","chronic pain","pain catastrophizing","multidisciplinary treatment","therapeutic exercice","pain neuroscience education","cognitive behavioural therapy","therapeutic education","2025-03-25",{"date":465,"type":39},"2025-03-30",{"date":467,"type":39},"2025-01-14",{"date":469,"type":21},"2026-03",{"name":45,"class":46},{"id":472,"slug":473,"hasResults":11,"nctId":474,"briefTitle":475,"officialTitle":476,"acronym":477,"eligibilityCriteria":478,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":479,"enrollmentInfo":480,"targetDuration":4,"studyType":22,"phases":482,"briefSummary":483,"conditions":484,"keywords":486,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":496,"lastUpdatePostDateStruct":497,"startDateStruct":499,"completionDateStruct":501,"leadSponsor":503,"locationsCount":47},"100547308","active-young-healthy-mind-the-youngfitt-project-100547308","NCT06406283","Active Young, Healthy Mind. The YoungFitT Project","Active Young, Healthy Mind: Strategies for Brain Health and Psychological Well-being in Young Adults: A Randomized Mixed-method Study With and Without Virtual Reality (VR) (YoungFitT: Young Fitness Technology)","YoungFitT","Inclusion Criteria:\n\n* Individuals aged 18-25 years old\n* Fluency in Catalan or Spanish (I.e., able to understand and speak)\n* Accept to take part in the study and sign the informed consent according to the Declaration of Helsinki.\n\nExclusion Criteria:\n\n* Severe Neurological or psychiatric history\n* Alcohol or drug abuse history\n* Injury that prevents exercise\n\nExclusion criteria only for MRI examination:\n\n* Claustrophobia\n* Medical device (e.g., pacemaker implants, stents)\n* Other metal objects in the body\n\nExclusion criteria only for VR study:\n\n* Dizziness\n* Contraindications or troubles that could condition the use of VR","25 Years",{"count":481,"type":21},219,[24],"The main objective of YoungFitT Project is to study the effect and neuro-psycho-biological mechanisms of mind and body interventions, also in the form of virtual reality (VR), on brain health, cognitive and psychological well-being of college students. The investigators have adopted an inter and multidisciplinary and multimodal approach to provide a more integrative perspective using cognitive, psychological, biochemical, and neuroimaging measurements. The investigators hypothesize that all three interventions Mindfulness-Based Stress Reduction (MBSR), Qigong, and High-Intensity Functional Training (HIFT) will produce gains in cognitive functions and psychological well-being at three months compared to baseline. Also, all three interventions will induce changes in the microbiota and brain structure and function. Finally, using a VR environment for these interventions will provide greater adherence and cognitive and psychological well-being benefits than conventional training.",[485],"University Students",[487,488,489,490,491,492,493,494,495],"Well-being","Physical exercise","Qigong","Mindfulness","Neuroimaging","Intervention","Randomization","Cognition","Virtual environment","2024-05-06",{"date":498,"type":39},"2024-05-09",{"date":500,"type":39},"2023-12-20",{"date":502,"type":21},"2026-09-18",{"name":45,"class":46},{"id":505,"slug":506,"hasResults":11,"nctId":507,"briefTitle":508,"officialTitle":508,"acronym":509,"eligibilityCriteria":510,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":511,"enrollmentInfo":512,"targetDuration":4,"studyType":22,"phases":514,"briefSummary":515,"conditions":516,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":524,"lastUpdatePostDateStruct":525,"startDateStruct":527,"completionDateStruct":529,"leadSponsor":531,"locationsCount":47},"100461399","efficacy-of-the-use-of-diaries-in-intensive-care-units-100461399","NCT05288140","Efficacy of the Use of Diaries in Intensive Care Units","QUADERN","Inclusion Criteria:\n\n* admitted intensive care unit\n* sedated and mechanically ventilated for 24hours\n* signed consent\n* not language barrier\n* willingness to attend follow-up visits\n\nExclusion Criteria:\n\n* verbal manifestation of psychiatric, mental or cognitive antecedents\n* who do not coluntarily agree to participate","100 Years",{"count":513,"type":21},240,[24],"Randomized clinical trial that aims to evaluate the impact of the use of a diary in patients and relatives of patients admitted to an ICU in relation to usual practice in terms of health-related quality of life, the post-traumatic stress and anxiety\u002Fdepression at 2, 6 and 12 months after ICU discharge.",[517,518,519,520,521,522,259,258,523],"Diary (Blank Journal)","Intensive Care Unit","Patient","Family","PICS","Stress","Quality of Life","2024-03-26",{"date":526,"type":39},"2024-03-27",{"date":528,"type":39},"2022-01-01",{"date":530,"type":21},"2026-12-31",{"name":45,"class":46},""]