[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Central Florida\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":651},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,41,0,25,[9,53,83,104,133,161,186,221,244,271,299,323,350,379,402,425,445,475,502,522,545,570,591,609,630],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100627164","ai-based-mobile-intervention-on-medication-non-adherence-and-transition-100627164",false,"NCT07445074","AI-Based Mobile Intervention on Medication Non-Adherence and Transition","Inclusion Criteria:\n\n* Diagnosed with epilepsy\n* Currently prescribed anti-seizure medicine (ASMs)\n* Identified as part of an underserved population, defined as meeting at least one of the following: member of a racial or ethnic group historically underrepresented in research or healthcare or low-income status (e.g., eligible for public assistance or government-subsidized health coverage)\n* Are between 14-17 years old and able to provide assent, with a parent or LAR present to receive app notifications throughout the study\n* Are between 18-24 years old and able to provide informed consent\n* Able to read, speak, and write in English\n* Resides in Florida\n* Receive outpatient medical services\n\nExclusion Criteria:\n\n* They do not own a mobile device with internet access.\n* They have a history of severe intellectual disability.\n* They are unable to operate a mobile device (keyboard or touchscreen).\n* Reside in an in-patient setting.\n* Adults unable to consent.\n* Pregnant women (excluded because pregnancy is not relevant to the study focus).\n* Prisoners.","ALL","14 Years","24 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to examine whether the AI-personalized version of the Medilepsy® app is more effective than the non-AI (standard version without AI personalization) can improve key outcomes, such as medical adherence and transition readiness, among underserved adolescents and young adults with epilepsy, ages 14-24, in Florida, USA.\n\nOutcomes are organized into primary (effectiveness), secondary (usability), and exploratory (language experience) endpoints.",[27,28],"Epilepsy","Seizure",[30,31,32,33,34,27,35,36,37,38,39],"Adherence","Anti-seizure medications","Artificial Intelligence","Chat-bot","Chronic disease","Mobile Applications","Self-management","Seizures","Transition","Underserved","RECRUITING","2026-05-27",{"date":43,"type":44},"2026-05-29","ACTUAL",{"date":46,"type":21},"2026-05",{"date":48,"type":21},"2026-12",{"name":50,"class":51},"University of Central Florida","OTHER",2,{"id":54,"slug":55,"hasResults":12,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},"100638084","lipid-screening-study-100638084","NCT07579325","Lipid Screening Study","Prospective Screening for Elevated Lipoprotein(a) in an Adult Primary Care Population","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Receiving care at UCF Health primary care clinic\n* Able to understand and provide informed consent and HIPAA authorization\n\nExclusion Criteria:\n\n* Patient self discloses any medical condition that would make venipuncture unsafe\n* Pregnant women",true,"18 Years",{"count":63,"type":21},30,"OBSERVATIONAL","The purpose of this pilot study is to estimate the prevalence of elevated Lipoprotein (a) in an adult primary care population and to describe the distribution of atherogenic lipid markers within this cohort. This pilot study will provide preliminary data to inform future cardiovascular risk assessment initiatives in primary care.",[67],"Lipoprotein (a)",[69,70,71,72,73],"lipoprotein (a)","HDL and LDL","HDL","LDL","lipid Panel","2026-05-06",{"date":76,"type":44},"2026-05-12",{"date":78,"type":44},"2026-05-05",{"date":80,"type":21},"2026-08-01",{"name":50,"class":51},1,{"id":84,"slug":85,"hasResults":12,"nctId":86,"briefTitle":87,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":12,"sex":16,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":4,"studyType":22,"phases":93,"briefSummary":94,"conditions":95,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":101,"leadSponsor":103,"locationsCount":82},"100628620","feasibility-and-acceptability-of-a-pediatric-referral-to-summer-day-camps-to-treat-obesity-in-children-from-low-income-households-100628620","NCT07464015","Feasibility and Acceptability of a Pediatric Referral to Summer Day Camps to Treat Obesity in Children From Low-Income Households","Inclusion Criteria:\n\n* Overweight or Obese\n* Attends pediatric clinic\n* Medicaid Insured\n\nExclusion Criteria:\n\n* None","5 Years","11 Years",{"count":92,"type":21},80,[24],"Children from low-income households have a 25-30% higher prevalence of OWOB compared to their higher-income peers. The lack of feasible and effective treatments to address obesity in children with OWOB and from low-income household's points to a real need for prioritization and urgency. The U.S. Preventive Services Task Force (USPSTF) notes several shortcomings with current behavioral interventions and clinical practice to treat children with OWOB. Current efforts lack the necessary intensity recommended by USPSTF (26-52 hours in a 6-month period); incorporate multi-component interventions that are not feasible to consistently deliver; do not consider barriers to services\u002Fprograms, such as cost; do not explore collaborative relationships between providers and community programs, and are expressed as 'treatment', therefore, perpetuating the stigma of being overweight\u002Fobese. Our project rationale focuses on addressing these limitations during a critical time for accelerated weight-gain in children with OWOB, summer. Our pilot randomized clinical trial will provide free access for children to attend summer day camps (SDCs) as a treatment for OWOB. SDCs are settings where children show high levels of physical activity, consume foods\u002Fbeverages that meet federal nutrition guidelines, and maintain a consistent sleep schedule during summer. Unfortunately, not all children have access to SDCs. Our team surveyed more than 100 parents\u002Fguardians (84% Medicaid) who have a child with OWOB and receives treatment at a pediatric clinic and \\~75% reported that they would like to receive a voucher to attend a SDC and that cost was the number one reason why their child did not attend. The proposed pilot randomized clinical trial will randomize a total of 80 children with OWOB (5-11 years) who are covered by Medicaid, into two groups: (1) those who receive a pediatric voucher referral (PVR) from an pediatrician or nurse practitioner to attend an existing SDC for 8 weeks free-of- charge (n=40) or (2) those who continue to receive standard care (control; n=40). By leveraging the expertise of primary care providers and partnering with two well-positioned community partners, our team will evaluate a highly promising intervention to address cost as a barrier for children\u002Ffamilies attending summer programming by addressing the following specific aims: 1) to examine the feasibility (intervention delivery) and acceptability (intervention uptake) of the PVR program, 2) to determine the preliminary effectiveness of the PVR program on weight outcomes, and the potential mediating influence of activity, sleep, and diet on any observed changes, and 3) to qualitatively explore the facilitators\u002Fbarriers of participation in the PVR program and to identify what children and families face during the school year and summer in relation to weight management. Findings will inform the design of a R01 clinical trial. Long term goals of this proposal are to influence policies for subsidizing access to local community SDCs for children\u002Ffamilies who meet health criteria (i.e., OWOB). Scalability of this approach is promising given the widespread presence of SDCs and pediatric health clinics in communities.",[96],"Obesity & Overweight","2026-04-27",{"date":99,"type":44},"2026-05-01",{"date":46,"type":21},{"date":102,"type":21},"2027-09",{"name":50,"class":51},{"id":105,"slug":106,"hasResults":12,"nctId":107,"briefTitle":108,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":22,"phases":113,"briefSummary":115,"conditions":116,"keywords":119,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":128,"startDateStruct":129,"completionDateStruct":130,"leadSponsor":132,"locationsCount":82},"100592870","early-phase-1-quadriceps-motor-unit-adaptation-to-simulated-knee-injury-100592870","NCT06999057","Quadriceps Motor Unit Adaptation to Simulated Knee Injury","Inclusion Criteria:\n\n1. Age 18-30 years\n2. Physically active (Tegner ≥ 5)\n3. No prior lower-limb surgery or major injury\n\nExclusion Criteria:\n\n1. Lower limb surgery or significant injury in past 2 years\n2. Cardiopulmonary, neurological, or psychiatric disorders\n3. Needle\u002Felectrical stimulation anxiety\n4. Medications affecting neuromuscular or psychological function\n5. Pregnancy\n6. Allergic to lidocaine\n7. Inability to elicit Hoffmann reflex","30 Years",{"count":112,"type":21},45,[114],"EARLY_PHASE1","This study investigates how simulated knee injury-via artificial joint effusion or deafferentation-affects quadriceps motor unit behavior in healthy young adults. Participants will complete neuromuscular testing during a single 2-hour lab session. This research seeks to improve understanding of muscle inhibition and inform interventions after real-world knee trauma.",[117,118],"Muscle Inhibition","Knee Injury Simulation",[120,121,122,123,124,125,126,127],"Quadriceps","Electromyography","Motor Unit","Knee Effusion","Lidocaine","Deafferentation","Neuromuscular Adaptation","Muscle Strength",{"date":99,"type":44},{"date":80,"type":21},{"date":131,"type":21},"2027-08-01",{"name":50,"class":51},{"id":134,"slug":135,"hasResults":12,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":4,"eligibilityCriteria":139,"healthyVolunteers":12,"sex":16,"minAge":140,"maxAge":4,"enrollmentInfo":141,"targetDuration":4,"studyType":22,"phases":143,"briefSummary":144,"conditions":145,"keywords":148,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":155,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":52},"100503698","serious-gaming-for-chemotherapy-induced-nausea-and-vomiting-100503698","NCT05838638","Serious Gaming for Chemotherapy-induced Nausea and Vomiting","Serious Gaming for Chemotherapy-induced Nausea and Vomiting in Older Adults With Cancer: A Randomized Clinical Trial","Inclusion Criteria:\n\n* age 60 or older\n* newly diagnosed with cancer\n* treatment with any chemotherapeutic agent of moderate or high emetic potential\n* on a 2, 3 or 4 week treatment cycle\n* proficient in English\n* has a telephone\n\nExclusion Criteria:\n\n* previous diagnosis and\u002For treatment for cancer\n* end stage disease with less than 6 months to live\n* visually or hearing impaired without corrective device","60 Years",{"count":142,"type":21},610,[24],"The purpose of this study is to examine the effectiveness of a technology-based intervention for managing nausea and vomiting in older adults with cancer. Participants will be randomized to either an intervention or control group. Outcomes such as symptom severity, quality of life, and resource use will be examined.",[146,147],"Neoplasms","Chemotherapy-induced Nausea and Vomiting",[149,150,151,152,153,154],"aged","digital technology","nausea","neoplasm","Drug related side effects and adverse reactions","self-management",{"date":99,"type":44},{"date":157,"type":44},"2023-06-09",{"date":159,"type":21},"2027-06-30",{"name":50,"class":51},{"id":162,"slug":163,"hasResults":12,"nctId":164,"briefTitle":165,"officialTitle":166,"acronym":4,"eligibilityCriteria":167,"healthyVolunteers":12,"sex":16,"minAge":61,"maxAge":168,"enrollmentInfo":169,"targetDuration":4,"studyType":22,"phases":171,"briefSummary":172,"conditions":173,"keywords":175,"overallStatus":178,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":183,"leadSponsor":185,"locationsCount":82},"100634757","comparing-yoga-nidra-yoga-and-control-condition-on-pain-in-individuals-with-chronic-low-back-pain-100634757","NCT07543835","Comparing Yoga Nidra, Yoga, and Control Condition on Pain in Individuals With Chronic Low Back Pain","Comparing the Effects of Yoga Nidra, Yoga, and Control Condition on Thermal Pain Processing, Psychological Factors, and Movement-Evoked Pain in Individuals With Chronic Low Back Pain","Inclusion Criteria:\n\n* low back pain classified as symptoms localized to the posterior region of the trunk, extending from the lower margin of the last rib to the gluteal folds\n* low back pain for three months or longer with a average pain intensity = 3\u002F10 on the 11-point numeric pain rating scale (NPRS) within the previous twenty-four hours\n* experienced three or more low back pain episodes within the past 3 years\n* fluency in English\n* ability to attend all visits\n* reliable email access.\n\nExclusion Criteria:\n\n* systemic or neurological conditions that could alter sensation (e.g., uncontrolled diabetes)\n* any surgery or fracture within 6 months\n* blood-clotting disorders or contraindications to pressure and heat stimuli\n* current pregnancy and requirement for medical clearance to exercise (screened with Physical Activity Readiness Questionnaire-Plus PAR-Q+\n* not receiving physical therapy or chiropractor treatments for low back pain","65 Years",{"count":170,"type":21},27,[24],"Individuals with chronic low back pain will undergo a yoga, yoga nidra, and control condition on separate visits. Each visit, before and after the intervention, participants with rate their pain in response to heat stimuli, a sit to stand task, and questionnaires.",[174],"Low Back Pain",[176,177],"low back pain","yoga","NOT_YET_RECRUITING","2026-04-14",{"date":181,"type":44},"2026-04-22",{"date":80,"type":21},{"date":184,"type":21},"2027-07-01",{"name":50,"class":51},{"id":187,"slug":188,"hasResults":12,"nctId":189,"briefTitle":190,"officialTitle":190,"acronym":191,"eligibilityCriteria":192,"healthyVolunteers":12,"sex":193,"minAge":61,"maxAge":194,"enrollmentInfo":195,"targetDuration":4,"studyType":22,"phases":197,"briefSummary":198,"conditions":199,"keywords":203,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":82},"100610094","effectiveness-of-interventions-to-promote-physical-activity-during-pregnancy-100610094","NCT07223112","Effectiveness of Interventions to Promote Physical Activity During Pregnancy","SLMM","Eligibility Criteria\n\n* 18 to 45 years old\n* speak English\n* 8 to 12 weeks pregnant (gestation)\n* singleton pregnancy (no twins or more)\n* self-report less than 150 minutes\u002Fweek of moderate-intensity physical activity\n* have or are willing to identify a physical activity partner\n* have a cell phone with the capacity for Fitbit application (app.); secure transmission of Fitbit data; receive coaching text messages or, if not, a computer they can use to synch the fitbit, send data, and receive email messages in lieu of texts.\n\nExclusion Criteria\n\n• Women with physical activity restrictions (e.g., placenta previa) that prevent them from completing ACOG recommended pregnancy physical activity","FEMALE","45 Years",{"count":196,"type":21},60,[24],"Pregnant women are more sedentary (sit, recline, lie down more) on average than non-pregnant women (more than 12 versus less than 8 waking sedentary hours\u002Fday). Sedentary behavior has been related to psychological distress, pregnancy weight gain, impaired sleep and very large size infants, while adequate physical activity has been found to improve mental health, decrease risk of high blood pressure in pregnancy and lower risk of preterm birth infants (less than 37 weeks gestation). Decreased sedentary behavior and increased physical activity may be crucial and neglected lifestyle behavior changes that can be promoted to reduce these and other maternal health and birth outcome problems among pregnant women.",[200,201,202],"Pregnancy","Sedentary Behavior","Insufficient Physical Activity",[204,205,206,207,208,209,210,211,212],"Sit Less, Move More effectiveness for pregnant women","physical activity habit formation","sedentary behavior habit reversal","sedentary time disruption","wearable device","nudging","health coach","social support","behavior change","2026-03-10",{"date":215,"type":44},"2026-03-11",{"date":217,"type":44},"2026-02-01",{"date":219,"type":21},"2027-08-31",{"name":50,"class":51},{"id":222,"slug":223,"hasResults":12,"nctId":224,"briefTitle":225,"officialTitle":225,"acronym":4,"eligibilityCriteria":226,"healthyVolunteers":12,"sex":16,"minAge":61,"maxAge":227,"enrollmentInfo":228,"targetDuration":4,"studyType":22,"phases":230,"briefSummary":231,"conditions":232,"keywords":234,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":243,"locationsCount":82},"100529295","improving-hiv-care-continuum-outcomes-among-formerly-incarcerated-individuals-through-critical-time-legal-interventions-100529295","NCT06171919","Improving HIV Care Continuum Outcomes Among Formerly Incarcerated Individuals Through Critical Time Legal Interventions","Inclusion Criteria:\n\n* 18 years or older\n* Living with HIV (as confirmed by medical record)\n* HIV viral load of more than 200 copies\u002FmL (as confirmed by medical record)\n* Report history of incarceration\n* Willing and able to consent to participate in the trial (including accessing their medical records at the health care organization)\n* No intent to relocate within the 6 months following their enrollment in the study.\n\nExclusion Criteria:\n\n* Individuals who self-report having been sentenced to serve under state or federal custody, with a sentence to begin within 6 months from proposed enrollment in the study","100 Years",{"count":229,"type":21},100,[24],"The purpose of this research is to better understand the impact of receiving legal aid on HIV care continuum outcomes among formerly incarcerated individuals. In addition, the investigators would like to assess the effectiveness of a comprehensive training for providers in increasing knowledge about medical legal partnerships and improving clinic level outcomes, including communication among providers. The training includes several topics including health disparities impacting formerly incarcerated individuals, health-harming legal needs and risks, screening for health-harming legal needs and risks, medical-legal partnership structure and operations, prerequisites for MLPs, embedding legal expertise within regularized case management, co-location of legal services, and data collection and analysis.",[233],"HIV",[233,235,236],"Care","Incarcerated","2026-02-19",{"date":239,"type":44},"2026-02-23",{"date":241,"type":44},"2024-10-05",{"date":80,"type":21},{"name":50,"class":51},{"id":245,"slug":246,"hasResults":12,"nctId":247,"briefTitle":248,"officialTitle":249,"acronym":4,"eligibilityCriteria":250,"healthyVolunteers":60,"sex":16,"minAge":251,"maxAge":4,"enrollmentInfo":252,"targetDuration":4,"studyType":22,"phases":253,"briefSummary":254,"conditions":255,"keywords":259,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":263,"lastUpdatePostDateStruct":264,"startDateStruct":266,"completionDateStruct":268,"leadSponsor":270,"locationsCount":82},"100616473","university-of-central-florida-music-study-100616473","NCT07306065","University of Central Florida Music Study","Scientific Proof of Music Therapy's Impact on Alzheimer's Disease","Inclusion Criteria:\n\n* 50 years old or older.\n\n  * 20 adults with no mild-cognitive impairment\n  * 20 adults with mild-cognitive impairment\n  * 20 adults with Alzheimer's disease\u002F dementia.\n* participant or the participant's legally authorized representative must be able to read or speak English and agree to comply with study procedures.\n* pregnant women may chose to participate\n\nExclusion Criteria:\n\n* 49 years and younger\n* prisoners\n* unable to understand English and provide consent","50 Years",{"count":196,"type":21},[24],"The purpose of this study is to scientifically validate the impact of music therapy on Alzheimer's disease (AD) by analyzing molecular biomarkers in salivary exosomes. Exosomes are extracellular vesicles that carry molecular signals from brain cells, providing a non-invasive method to assess physiological changes.",[256,257,258],"Alzheimers Disease","Dementia","Dementia Alzheimer Type",[260,261,262],"Alzheimer s disease","music","dementia","2025-12-18",{"date":265,"type":44},"2025-12-29",{"date":267,"type":44},"2025-08-28",{"date":269,"type":21},"2026-03",{"name":50,"class":51},{"id":272,"slug":273,"hasResults":12,"nctId":274,"briefTitle":275,"officialTitle":276,"acronym":4,"eligibilityCriteria":277,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":278,"targetDuration":280,"studyType":64,"phases":4,"briefSummary":281,"conditions":282,"keywords":289,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":292,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":82},"100609461","ucf-mammochat-image-repository-100609461","NCT07214883","UCF MammoChat: Image Repository","UCF MammoChat: An AI-Driven Platform for Personalized Breast Cancer Patient Support -Image Repository","Inclusion Criteria:\n\n* Adults, ages 18 and older\n* Had a radiographic breast cancer imaging test, either for screening or diagnosis of breast cancer, with either positive or negative results performed in a US institution.\n* Have an email account with access to a reliable internet connection or smartphone\n* Pregnant women may choose to participate.\n\nExclusion Criteria:\n\n* Minors , ages under 18\n* Prisoners\n* Adults who are unable to provide consent.",{"count":279,"type":21},20000,"1 Year","This study aims to develop AI models to better read diagnostic mammograms for various populations and types of breast cancer, using the images that participants donate and their responses from study questionnaire to improve patient outcomes. This study also aims to provide mammography images to participants.",[283,284,285,286,287,288],"Breast Cancer","Breast Cancer Awareness","Breast Cancer Detection","Breast Cancer Survivors","Breast Cancer Female","Breast Cancer Diagnosis",[283,32,290],"AI","2025-10-08",{"date":293,"type":44},"2025-10-09",{"date":295,"type":44},"2025-09-03",{"date":297,"type":21},"2026-06-30",{"name":50,"class":51},{"id":300,"slug":301,"hasResults":12,"nctId":302,"briefTitle":303,"officialTitle":304,"acronym":4,"eligibilityCriteria":305,"healthyVolunteers":12,"sex":193,"minAge":61,"maxAge":4,"enrollmentInfo":306,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":307,"conditions":308,"keywords":313,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":317,"startDateStruct":318,"completionDateStruct":320,"leadSponsor":322,"locationsCount":82},"100609412","follicular-fluid-micrornas-in-ovarian-aging-and-reproduction-100609412","NCT07214246","Follicular Fluid microRNAs in Ovarian Aging and Reproduction","Investigating the Role of Follicular Fluid microRNAs in Ovarian Aging and Assisted Reproductive Success","Inclusion Criteria:\n\n* Women undergoing IVF treatment due to male factor infertility or nonovarian causes.\n* Age groups: younger women \\\u003C31 years and older women \\>38 years.\n* Regular menstrual cycles.\n* Willing and able to provide informed consent.\n\nExclusion Criteria:\n\n* Minors (under 18 years) and women aged 32-37 years\n* Diagnosis of polycystic ovarian syndrome (PCOS).\n* History of recurrent pregnancy loss.\n* Presence of endometriosis.\n* Diagnosis of ovarian insufficiency.\n* Metabolic disorders (e.g., diabetes).\n* History of ovarian surgery or chemotherapy.\n* Any condition that might impact follicular fluid quality or IVF outcomes.",{"count":229,"type":21},"The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes. The goal is to identify noninvasive molecular markers that correlate with oocyte quality and reproductive potential, particularly in women of advanced maternal age.",[309,310,311,312],"Ovarian Aging","In Vitro Fertilisation (IVF) Treatment","InVitro Fertilization","In Vitro Fertilization Outcome",[314,315,316],"IVF","In vitro fertilization","Follicular fluid",{"date":293,"type":44},{"date":319,"type":44},"2025-09-22",{"date":321,"type":21},"2026-09",{"name":50,"class":51},{"id":324,"slug":325,"hasResults":12,"nctId":326,"briefTitle":327,"officialTitle":328,"acronym":4,"eligibilityCriteria":329,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":330,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":332,"conditions":333,"keywords":335,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":344,"startDateStruct":346,"completionDateStruct":348,"leadSponsor":349,"locationsCount":82},"100599943","harmful-algal-blooms-100599943","NCT07091058","Harmful Algal Blooms","Health Outcomes Associated With Algal Blooms of Cyanobacteria and Red Tide in in Florida: Long-Term Health Impacts of Harmful Algal Bloom Exposure, Phase 2","Inclusion Criteria:\n\n* 18 years or older\n* live, visit, and\u002F or work in the following Florida counties: Indian River, St. Lucie, Charlotte, Collier, Hendry, Hillsborough, Lee, Manatee, Martin, Monroe, Okeechobee, Palm Beach, Pasco, Pinellas, Indian River, and\u002For Sarasota\n* able to read and understand English\n\nExclusion Criteria:\n\n* unable to independently consent\n* younger than 18 years old\n* prisoner\n* pregnant women",{"count":331,"type":21},400,"The purpose of this study is to compare the frequency of symptoms, exposure and health impacts in persons living in areas where they are exposed to bloom and non-bloom periods of cyanobacteria and red tide in Florida.",[334],"Red Tide",[336,337,338,339,340,341,342],"algae","Cyanobacteria","red tide","cyanotoxin","Harmful Algal Blooms (HABs)","microcystins","brevetoxin","2025-07-21",{"date":345,"type":44},"2025-07-29",{"date":347,"type":44},"2024-11-13",{"date":297,"type":21},{"name":50,"class":51},{"id":351,"slug":352,"hasResults":12,"nctId":353,"briefTitle":354,"officialTitle":355,"acronym":356,"eligibilityCriteria":357,"healthyVolunteers":12,"sex":16,"minAge":61,"maxAge":358,"enrollmentInfo":359,"targetDuration":4,"studyType":22,"phases":361,"briefSummary":362,"conditions":363,"keywords":366,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":371,"lastUpdatePostDateStruct":372,"startDateStruct":374,"completionDateStruct":376,"leadSponsor":378,"locationsCount":82},"100551980","motor-imagery-for-treatment-enhancement-and-efficacy-in-persons-with-apraxia-of-speech-100551980","NCT06467136","Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of Speech","Motor Imagery for Treatment Enhancement and Efficacy (MI-TEE) in Persons With Apraxia of Speech","MI-TEE","Inclusion Criteria:\n\n* Between the ages of 18 and 90 yrs. old\n* At least 6 months post left hemisphere stroke\n* Demonstrate AOS\n* Speak English as their primary language\n* Pass a hearing screening at 35 dB HL at 500, 1K, and 2K Hz for at least one ear\n* Normal or corrected to normal visual acuity\n\nExclusion Criteria:\n\n* Unable to follow two-step commands and greater than moderate aphasia\n* Moderate - severe dysarthria\n* Untreated depression or other psychiatric illness\n* Degenerative neurological illnesses\n* Less than 3 on the MIQ-RS77\n* Less than a 4 on 3\u002F5 domains on the FACETS\n* Less than a 23 on the Raven's Coloured Progressive Matrices\n* Receive other speech therapy while participating in the study","90 Years",{"count":360,"type":21},18,[24],"Treatment of post-stroke apraxia of speech (AOS) requires frequent and ongoing practice with a speech-language pathologist to facilitate lasting behavioral change, which is costly and, therefore, inaccessible to many patients. Thus, there is a critical need to identify novel, cost-effective ways to supplement speech therapy to increase opportunities for practice and optimize treatment outcomes. Our long-term goal is to develop an effective, home-practice, computer-based, motor imagery protocol Motor Imagery for Treatment Enhancement and Efficacy (MI-TEE) which will serve as an adjunct to routine speech therapy to optimize treatment response in persons with AOS. The overall objectives of this application are to (i) evaluate the acceptability and feasibility of MI-TEE as a home practice program and (ii) determine the efficacy of MI-TEE with speech therapy, compared to speech therapy alone, in improving speech production in people with AOS. Our central hypothesis is that MI-TEE will be an accessible, feasible, and efficacious adjunct to speech therapy. To attain our objectives, the following specific aims will be pursued using two single-subject experimental designs with multiple baselines across participants (n=18): 1) Evaluate the acceptability and feasibility of MI-TEE as an adjunct to speech therapy for the rehabilitation of AOS; and 2) Compare the efficacy of adjunctive MI-TEE plus standard speech therapy to standard speech therapy alone. Under the first aim, observational data, surveys, and semi-structured interviews will be employed to assess the acceptability (perceived satisfaction, appropriateness, and intent to continue use) and feasibility (recruitment, retention, and intervention adherence rates) of MI-TEE. For the second aim, accuracy of articulation for trained words and untrained words (generalization) will be measured pre-treatment, repeatedly during the treatment phase, and post-treatment. Improvements in speech accuracy will be documented using a binary scoring system (correct\u002Fincorrect). Multilevel analyses will be used to address rate of acquisition, overall change, and response variation across participants.",[364,365],"Apraxia, Oral","Apraxia of Speech",[367,368,369,370],"Treatment of Apraxia of Speech","Home Practice for Apraxia of Speech","AOS","Apraxia of speech","2025-06-22",{"date":373,"type":44},"2025-06-26",{"date":375,"type":44},"2023-12-11",{"date":377,"type":21},"2026-07-31",{"name":50,"class":51},{"id":380,"slug":381,"hasResults":12,"nctId":382,"briefTitle":383,"officialTitle":384,"acronym":4,"eligibilityCriteria":385,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":386,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":388,"conditions":389,"keywords":391,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":394,"lastUpdatePostDateStruct":395,"startDateStruct":397,"completionDateStruct":399,"leadSponsor":401,"locationsCount":82},"100550551","gut-microbiomes-in-hd-100550551","NCT06448546","Gut Microbiomes in HD","Investigating the Role of the Gut Microbiome in Huntington's Disease","* Inclusion Criteria:\n\n  * 18 years or older\n  * Provide informed consent\n  * Able to read and speak English\n  * Agree to comply with study procedures\n* Inclusion criteria for the control group include:\n\n  * CAG repeat length ≤ 26.\n  * BMI 18.5-24.9\n* Inclusion criteria for experimental group 1 include:\n\n  * BMI \\\u003C 18.5 (underweight) or significant, involuntary weight loss within the past 12 months.\n  * CAG repeat length 40 - 59.\n  * Documentation of the Clinical Diagnosis of HD with a high level of certainty (\\>99% confidence) using the validated Unified Huntington's Disease Rating Scale (UHDRS).\n  * Stage I-III on the Functional Assessment component of the UHDRS\n* Inclusion criteria for experimental group 2 include:\n\n  * BMI \\> 25.0 (overweight - obesity) or BMI ≤ 25.0 with significant, unexplained weight gain within the past 12 months\n  * CAG repeat length 40 - 59.\n  * Documentation of the Clinical Diagnosis of HD with a high level of certainty (\\>99% confidence) using the validated UHDRS.\n  * Stage I-III on the Functional Assessment component of the UHDRS\n* Exclusion Criteria:\n\n  * CAG repeat length ≥ 60 to exclude participants with juvenile onset HD.\n  * CAG repeat length 36 - 39 to exclude participants with reduced penetrance. As this is a pilot study, we are primarily interested in participants with typical HD characteristics.\n  * UHDRS Functional Capacity stage ≥ 4 to exclude late-stage HD patients who may be institutionalized and receive nutrition through a feeding tube.\n  * Use of any of the following drugs within the last 6 months:\n\n    * System antibiotics, antifungals, antivirals, or anti-parasitics (intravenous, intramuscular, or oral)\n    * Corticosteroids (intravenous, intramuscular, oral, nasal, or inhaled)\n    * Cytokines\n    * Methotrexate, immunosuppressive cytotoxic agents, or chemotherapy\n    * Commercial probiotics ≥ 100 million CFU (fermented foods, yogurts, and other homeopathic probiotics and prebiotics do not apply)\n  * Use of topical antibiotics or topical steroids within the last 7 days\n  * History of active, uncontrolled gastrointestinal disorders or diseases, including:\n\n    * Inflammatory bowel disease\n    * Ulcerative colitis\n    * Crohn's disease\n    * Irritable bowel syndrome\n    * Infectious gastroenteritis, colitis, or gastritis\n    * Clostridium difficile or Helicobacter pylori infection\n    * Persistent or chronic constipation or diarrhea\n  * Acute illness with or without fever at time of sample collection\n  * Positive for HIV, hepatitis B, or hepatitis C\n  * Confirmed or suspected immunodeficient condition\u002Fstate\n  * Major surgery of the GI tract, excluding cholecystectomy and appendectomy\n  * Unstable dietary history within the past month, such as elimination or significant increase of a major food group in the diet\n  * Recent history of chronic, excessive alcohol consumption\n  * Travel outside of the United States within the last 3 months",{"count":387,"type":21},36,"The purpose of this study is to find out if there is a connection between the naturally occurring bacteria in our bodies and the progression of Huntington disease. The investigators are trying to determine if patients who are diagnosed with adult-onset HD and who exhibit a rapid rate of disease progression have unique populations of bacteria in their gut as compared to patients with slower progression.",[390],"Huntington Disease",[390,392,393],"HD","Gut Microbiome","2025-06-15",{"date":396,"type":44},"2025-06-18",{"date":398,"type":21},"2025-06",{"date":400,"type":21},"2029-06",{"name":50,"class":51},{"id":403,"slug":404,"hasResults":12,"nctId":405,"briefTitle":406,"officialTitle":407,"acronym":4,"eligibilityCriteria":408,"healthyVolunteers":12,"sex":193,"minAge":61,"maxAge":409,"enrollmentInfo":410,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":412,"conditions":413,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":417,"lastUpdatePostDateStruct":418,"startDateStruct":420,"completionDateStruct":422,"leadSponsor":424,"locationsCount":82},"100591822","the-effect-of-the-menstrual-cycle-on-immune-cell-activity-and-recovery-after-resistance-exercise-100591822","NCT06985420","The Effect of the Menstrual Cycle on Immune Cell Activity and Recovery After Resistance Exercise","The Impact of the Menstrual Cycle on Innate Immune Cell Activation, Recruitment, and Adhesion Dynamics During Recovery From Damaging Resistance Exercise: Role of Neutrophils and Systemic Chemokines.","Inclusion Criteria:\n\n* Women between the ages of 18 and 40.\n* Must weigh at least 110 pounds.\n* Healthy as determined by medical history, physical activity readiness, and menstrual cycle questionnaires.\n* Actively resistance training for at least 6 months (minimum of 3 resistance training sessions per week, with at least one lower body session).\n* Pre-menopausal and have a regular menstrual cycle (eumenorrheic), with a clear start of menses (early follicular phase).\n* Not currently pregnant or planning to become pregnant during the study.\n* Have not used hormonal birth control or intrauterine devices in the past 3 months (or three full menstrual cycles).\n* Able to recall approximate start dates of their last 6 menstrual cycles.\n* Willing to follow study instructions, including avoiding exercise, alcohol, and caffeine before testing visits.\n* Free from previous or current lower body injuries that could limit performance.\n* Not regularly taking any medications that could interfere with the study.\n* Determined to have a high likelihood of successful blood draws by a certified phlebotomist.\n\nExclusion Criteria:\n\n* Do not give consent to participate.\n* Have been determined unfit to participate based on medical or activity history (using health questionnaires).\n* Currently take prescription or over-the-counter medication that could affect the study results.\n* Have a chronic illness requiring medical care.\n* Not currently resistance-trained (don't meet the exercise requirement).\n* Pregnant or planning to become pregnant during the study.\n* Do not have regular periods or have been diagnosed as amenorrhoeic (absence of menstruation).\n* Currently taking any performance-enhancing drugs.\n* Currently using hormonal birth control or intrauterine devices (IUDs), or have used them in the past three months (or three full menstrual cycles).\n* Determined unlikely to have a successful blood draw by a trained phlebotomist.\n* Weigh less than 110 pounds.","40 Years",{"count":411,"type":21},40,"The goal of this observational study is to learn how the menstrual cycle affects immune cell activation, recruitment, and recovery responses after resistance exercise in healthy, resistance-trained women aged 18-40. The main questions it aims to answer are:\n\nDoes the menstrual cycle influence neutrophil recruitment and adhesion after resistance exercise? Does the menstrual cycle affect markers of muscle damage and functional recovery? Researchers will compare three menstrual phases (early follicular, late follicular, and mid-luteal) to see if immune responses and recovery outcomes differ across these phases.\n\nParticipants will:\n\nComplete resistance exercise protocols across three different menstrual cycle phases.\n\nProvide blood samples to assess immune cell activation and muscle damage markers.\n\nTrack sleep, mood, and recovery with questionnaires and wear an accelerometer.",[414,415,416],"Healthy Women","Menstruation","Resistance Exercise","2025-05-14",{"date":419,"type":44},"2025-05-22",{"date":421,"type":44},"2024-08-16",{"date":423,"type":21},"2025-05",{"name":50,"class":51},{"id":426,"slug":427,"hasResults":12,"nctId":428,"briefTitle":429,"officialTitle":429,"acronym":4,"eligibilityCriteria":430,"healthyVolunteers":12,"sex":16,"minAge":61,"maxAge":431,"enrollmentInfo":432,"targetDuration":4,"studyType":22,"phases":434,"briefSummary":435,"conditions":436,"keywords":4,"overallStatus":178,"whyStopped":4,"lastUpdateSubmitDate":437,"lastUpdatePostDateStruct":438,"startDateStruct":440,"completionDateStruct":442,"leadSponsor":444,"locationsCount":82},"100591383","yoga-education-and-nidra-yen-for-chronic-low-back-pain-a-pilot-study-on-pain-modulation-well-being-and-sleep-100591383","NCT06979713","Yoga, Education, and Nidra (YEN) for Chronic Low Back Pain: A Pilot Study on Pain Modulation, Well-Being, and Sleep","Inclusion Criteria:\n\n* Chronic pain in lower back that has lasted for over three months\n* Pain intensity rated as 3\u002F10 or higher in the past 24 hours (0=no pain, 10=worst pain imaginable)\n\nExclusion Criteria:\n\n* non-English speaking\n* systemic medical conditions that affect sensation (such as uncontrolled diabetes)\n* History of surgery or fracture within the past six months\n* any blood clotting disorders (such as hemophilia)\n* any contraindication to the application of ice (blood pressure \\> 140\u002F90 mmHg, cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise)\n* Exceed pressure and heat sensory thresholds\n* Unable to access the internet or email\n* Pregnant\n* Unable to exercise without medical clearance (assessed on PAR-Q+ on first visit)","75 Years",{"count":433,"type":21},24,[24],"The purpose of this study is to compare the impact of yoga, pain education, and yoga nidra with pain acceptance intention to yoga, pain education, and relaxing music on pain intensity, well-being, and sleep quality. This is a pilot study trial of individuals with chronic low back pain. Participants will attend two sessions in the laboratory (week 1 and week 8) and complete their assigned intervention 2 x per week for 6 weeks at home. Participants will be randomized to either receive yoga postures targeting the low back, pain education, and yoga nidra with pain acceptance intention and motor imagery or yoga postures targeting the low back, pain education, and relaxing music.",[174],"2025-05-13",{"date":439,"type":44},"2025-05-20",{"date":441,"type":21},"2025-06-01",{"date":443,"type":21},"2026-03-15",{"name":50,"class":51},{"id":446,"slug":447,"hasResults":12,"nctId":448,"briefTitle":449,"officialTitle":449,"acronym":450,"eligibilityCriteria":451,"healthyVolunteers":12,"sex":16,"minAge":452,"maxAge":453,"enrollmentInfo":454,"targetDuration":4,"studyType":22,"phases":455,"briefSummary":456,"conditions":457,"keywords":463,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":437,"lastUpdatePostDateStruct":468,"startDateStruct":470,"completionDateStruct":472,"leadSponsor":474,"locationsCount":82},"100555444","measuring-aided-language-development-100555444","NCT06512168","Measuring Aided Language Development","MALD","Inclusion Criteria:\n\n* Clinical Identification of Down Syndrome or Cerebral Palsy + Significant Speech Impairment\n* Must Speak English as a Primary Language\n* Must Be Able to Express At Least 25 Words (using any communication mode)\n* Must Be Able to Accurately Select Picture Symbols on iPad Communication App with at Least 50% Accuracy\n* Vision and Hearing within Functional Limits or Corrected to be within Functional Limits for Study Activities\n\nExclusion Criteria:\n\n* Clinical Diagnosis of Autism or Social Communication Disorder\n* Primary Language Spoken is A Language Other than English","42 Months","60 Months",{"count":196,"type":21},[24],"The focus of the current study is to systematically investigate the psychometric properties of a range of aided language measures, which are based on the Graphic Symbol Utterance and Sentence Development Framework (Binger \\& Kent-Walsh).",[458,459,365,460,461,462],"Down Syndrome","Cerebral Palsy","Speech Sound Disorder","Speech Disorders in Children","Speech and Language Disorder",[464,465,466,467],"Augmentative and Alternative Communication","Complex Communication Needs","Assistive Technology","AAC",{"date":469,"type":44},"2025-05-16",{"date":471,"type":44},"2025-04-01",{"date":473,"type":21},"2028-03-31",{"name":50,"class":51},{"id":476,"slug":477,"hasResults":12,"nctId":478,"briefTitle":479,"officialTitle":480,"acronym":4,"eligibilityCriteria":481,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":482,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":484,"conditions":485,"keywords":488,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":494,"lastUpdatePostDateStruct":495,"startDateStruct":497,"completionDateStruct":499,"leadSponsor":501,"locationsCount":82},"100576140","university-of-central-florida-beeast-100576140","NCT06781424","University of Central Florida BEEAST","University of Central Florida Biobank for Extreme Environments, Aviation and Space Travel","Inclusion Criteria:\n\n* Primary Enrollees: adults, ages 18 and older, and persons who travel (such as space travel) or live in extreme environments (such as Antarctica).\n* Secondary Enrollees: Referred adult family members (such as siblings and spouses) of primary enrollees.\n* Tertiary Enrollees: Adult persons from the general public can enroll to serve as matching controls. Tertiary enrollees will be screened based on age, gender, race and ethnicity, country of residence, disease\u002F conditions and employment history.\n* Pregnant women may choose to enroll.\n\nExclusion Criteria:\n\n* adults unable to consent,\n* minors (under age 18)\n* prisoners",{"count":483,"type":21},10000,"Since the inception of aerospace travel, NASA has been collecting biospecimens from professional astronauts for research. With the recent growth of civilian aerospace travelers, there is a need for biospecimen banking for civilian astronauts. This protocol addresses this gap by being a biobank for civilian astronauts, their family members (to be controls) and others who are also doing travel to extreme environments (pilots, submariners).",[486,487],"Biospecimen Donation","Environmental Impact",[489,490,491,492,493],"donate","biobank","biospecimen","astronaut","pilot","2025-03-24",{"date":496,"type":44},"2025-03-26",{"date":498,"type":44},"2025-01-13",{"date":500,"type":21},"2075-01-13",{"name":50,"class":51},{"id":503,"slug":504,"hasResults":12,"nctId":505,"briefTitle":506,"officialTitle":506,"acronym":4,"eligibilityCriteria":507,"healthyVolunteers":60,"sex":16,"minAge":508,"maxAge":4,"enrollmentInfo":509,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":510,"conditions":511,"keywords":513,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":494,"lastUpdatePostDateStruct":516,"startDateStruct":518,"completionDateStruct":520,"leadSponsor":521,"locationsCount":82},"100529616","ucf-deciding-brains-100529616","NCT06176092","UCF Deciding Brains","Inclusion Criteria:\n\n* Younger adults only: Age 20-39 years old\n* Older adults only: Age 60 years old and older\n* Fluent English speaker\n* At least 8th grade education\n* On a stable regimen of medications\n* Able to provide verbal and written informed consent\n* Normal cognitive function\n\n  * Older adults only: The above will be assessed\u002Fconfirmed via cognitive screening assessments\n  * Telephone Interview for Cognitive Status (TICS-M; see \"Telephone Interview for Cognitive Status\" in Local Site Documents)\n\nExclusion Criteria:\n\n* Pregnant\n* Presence of:\n\n  * Schizophrenia Spectrum or Other Psychotic Disorders\n  * Bipolar and Related Disorders\n  * Depressive Disorders\n  * Anxiety Disorders\n  * Trauma- and Stressor-Related Disorders\n  * Substance-Related and Addictive Disorders\n* Current anticonvulsant, neuroleptic, or sedative use\n* Uncorrected visual and hearing impairments\n* Neurologic condition or event affecting the brain in the last 12 months (e.g., stroke, epilepsy, traumatic brain injury with \\>30-minute loss of consciousness)\n* History of brain surgery including tumor resection, deep brain resection, pallidotomy, and thalamotomy\n* Unstable medical illness (e.g., metastatic cancer)\n* Significant cardiovascular condition or event in the last 12 months (e.g., major heart attack, heart bypass surgery","20 Years",{"count":331,"type":21},"The purpose of this research study is to understand how people make trust-related decisions in healthy aging.\n\nParticipants will be asked to complete one study session on the University of Central Florida (UCF) campus. The study session will be conducted in a private testing room and include a series of computerized cognitive tasks and learning games, as well as surveys of your beliefs, preferences, and past experiences.\n\nThe study will take a total of approximately 3.5 hours to completed. You will be allowed to take breaks during the session as needed. If you begin the study but do not complete the session, you will receive credit commensurate with your participation.",[512],"Trust",[514,515],"Healthy","Psychology",{"date":517,"type":44},"2025-03-27",{"date":519,"type":44},"2023-09-21",{"date":400,"type":21},{"name":50,"class":51},{"id":523,"slug":524,"hasResults":12,"nctId":525,"briefTitle":526,"officialTitle":527,"acronym":4,"eligibilityCriteria":528,"healthyVolunteers":12,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":529,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":531,"conditions":532,"keywords":534,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":537,"lastUpdatePostDateStruct":538,"startDateStruct":540,"completionDateStruct":542,"leadSponsor":544,"locationsCount":82},"100564586","capability-assessment-for-diet-and-activity-cada-model-for-diabetes-100564586","NCT06631105","Capability Assessment for Diet and Activity (CADA) Model for Diabetes","Capability Assessment for Diet and Activity Model Extended to Include Screening and Knowledge in Diabetic Adults","Inclusion Criteria:\n\n* Adults over the age of 18.\n* Persons diagnosed with diabetes\n* Have an email account with access to a reliable internet connection or smartphone\n\nExclusion Criteria:\n\n* Minors , ages under 18\n* Adults not diagnosed with diabetes\n* Adults who are unable to provide consent.",{"count":530,"type":21},500,"This study investigates the capabilities related to diet, physical activity, screening, and knowledge among diabetic adults with or without a history of hospital admissions in Central Florida. The hypothesis is that enhancing these capabilities, based on the Capability Approach framework, can significantly reduce hospital readmissions and improve diabetes management outcomes.",[533],"Diabetes",[533,535,536],"Hospital Admission","Hospital","2025-03-19",{"date":539,"type":44},"2025-03-21",{"date":541,"type":44},"2025-01-10",{"date":543,"type":21},"2026-01-10",{"name":50,"class":51},{"id":546,"slug":547,"hasResults":12,"nctId":548,"briefTitle":549,"officialTitle":549,"acronym":4,"eligibilityCriteria":550,"healthyVolunteers":60,"sex":193,"minAge":61,"maxAge":4,"enrollmentInfo":551,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":553,"conditions":554,"keywords":557,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":562,"lastUpdatePostDateStruct":563,"startDateStruct":565,"completionDateStruct":567,"leadSponsor":569,"locationsCount":82},"100583479","university-of-central-florida-cerebank-100583479","NCT06876857","University of Central Florida CereBank","Inclusion Criteria:\n\n* Be 18 years or older.\n* Able to provide informed consent. Persons who are unable to provide an informed consent will need a Legally Authorized Representative (LAR) to sign the informed consent.\n\nExclusion Criteria:\n\n* minors (under age 18).\n* prisoners.\n* pregnant women.",{"count":552,"type":21},50000,"Millions of persons are affected by brain diseases. The CereBank will be used to support research studies aimed at improving the diagnosis and treatment of brain diseases. Brain diseases can be inherited; developed due to diseases or aging; or can be due to trauma. The Central Florida does not have a brain biobank to meet the needs of research. Therefore, it is necessary for the University of Central Florida to establish a brain biobank.",[486,555,556],"Brain Injury","Brain Diseases",[489,490,558,491,559,560,561],"brain","Alzheimer's Disease","Autism","Huntington's Disease","2025-03-10",{"date":564,"type":44},"2025-03-14",{"date":566,"type":44},"2025-02-25",{"date":568,"type":21},"2075-02-25",{"name":50,"class":51},{"id":571,"slug":572,"hasResults":12,"nctId":573,"briefTitle":574,"officialTitle":575,"acronym":4,"eligibilityCriteria":576,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":251,"enrollmentInfo":577,"targetDuration":4,"studyType":22,"phases":578,"briefSummary":579,"conditions":580,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":583,"lastUpdatePostDateStruct":584,"startDateStruct":586,"completionDateStruct":588,"leadSponsor":590,"locationsCount":82},"100583036","improving-mechanics-and-confidence-in-the-hip-hinge-100583036","NCT06871098","Improving Mechanics and Confidence in the Hip Hinge","Evaluating the Founder Exercise Technique: Improving Mechanics and Confidence in the Hip Hinge","Inclusion Criteria:\n\n* Age between 18 and 50 years.\n* Ability to perform physical exercises, including bending at the waist.\n* Ability to understand verbal and tactile cues.\n\nExclusion Criteria:\n\n* History of low back pain, pelvic pain, or hip pain.\n* Participants that have pain with the intervention.\n* Current or past musculoskeletal injuries affecting hip, knee, ankle, or foot function.\n* Any condition limiting the ability to perform or participate in physical activities.\n* Pregnant individuals or those planning pregnancy during the study duration.\n* This project will exclude the following special populations from participating: Adults unable to consent, individuals who are not yet adults (infants, children, teenagers), pregnant women, and prisoners. Pregnant women will be excluded due to the natural change in body mechanics that occurs during pregnancy, as this would lead to outliers in the data.",{"count":63,"type":21},[24],"To evaluate if the Founder exercise will significantly change participants kinematics when performing hip hinge movement. Secondary purpose is to evaluate if completing the Founder Exercise intervention will improve confidence in performing a hip hinge.",[581,582],"Hip Hinge","Hip and Knee Movement","2025-03-06",{"date":585,"type":44},"2025-03-11",{"date":587,"type":21},"2025-03-03",{"date":589,"type":21},"2026-03-23",{"name":50,"class":51},{"id":592,"slug":593,"hasResults":12,"nctId":594,"briefTitle":595,"officialTitle":596,"acronym":4,"eligibilityCriteria":597,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":598,"targetDuration":4,"studyType":22,"phases":599,"briefSummary":600,"conditions":601,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":583,"lastUpdatePostDateStruct":604,"startDateStruct":605,"completionDateStruct":606,"leadSponsor":608,"locationsCount":82},"100583035","novel-sock-design-on-ankle-and-postural-stability-100583035","NCT06871085","Novel Sock Design on Ankle and Postural Stability","Effectiveness of a Novel Sock Design on Ankle and Postural Stability","Inclusion Criteria:\n\n* Minimum of 18 years old or older\n* Able to perform the following actions with no pain or discomfort: sit-to-stand, jump, one leg stand\n* Must read, write, and speak sufficient English in order to complete subjective questionnaire\n\nExclusion Criteria:\n\n* Had a previous foot or leg injury\n* Had a foot condition at the time of their participation in the study\n* Had feelings of instability at the ankle\n* Had an ankle injury within the past 12 months\n* Had surgery on either lower extremity in the past\n* Had any torn ligaments or cartilage at the hip, knee, or ankle\n* Experienced radicular symptoms down either lower extremity\n* Had any allergies to the sock material used in the study\n\n  1. 80% nylon\n  2. 14% polyester\n  3. 6% elastane\n* Is currently pregnant",{"count":63,"type":21},[24],"This study uses a prospective cohort study design using a convenience sample to explore the sock's impact on various aspects of ankle function and overall stability. A secondary objective is measuring subjective changes in reported confidence levels in performing balance and stability exercises with and without sock",[602,603],"Ankle Stability","Postural Stability",{"date":585,"type":44},{"date":587,"type":21},{"date":607,"type":21},"2026-02-02",{"name":50,"class":51},{"id":610,"slug":611,"hasResults":12,"nctId":612,"briefTitle":613,"officialTitle":614,"acronym":4,"eligibilityCriteria":615,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":616,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":617,"conditions":618,"keywords":620,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":498,"lastUpdatePostDateStruct":623,"startDateStruct":625,"completionDateStruct":627,"leadSponsor":629,"locationsCount":82},"100576139","unity-cures-future-ucf-biobank-100576139","NCT06781411","Unity Cures Future (UCF) Biobank","Unity Cures Future (UCF) Biobank for Translational & Biomedical Research At UCF College of Medicine and Burnett School of Biomedical Sciences with Identifiable Human Tissue.","Inclusion Criteria:\n\n1. be able to read and understand English\n2. scheduled for a surgery or procedure that will result in the removal of human tissue.\n\nExclusion Criteria:\n\n1. Pregnant\n2. unable to provide an informed consent\n3. unable to understand or read in English\n4. minors (ages under 18)\n5. prisoners",{"count":483,"type":21},"Research scientists of the University of Central Florida College of Medicine (COM) and Burnett School of Biomedical Sciences (BSBS) conduct laboratory studies in biomedical and translational medical research for the purpose of understanding human disease and developing innovative methods for diagnosing, measuring, or treating disease or disease symptoms. The key research divisions are cancer, cardiovascular, immunity and pathogenesis, neuroscience, and molecular microbiology.",[619],"Tissue Banking",[621,489,622,490],"tissue","surgery",{"date":624,"type":44},"2025-01-17",{"date":626,"type":44},"2024-11-06",{"date":628,"type":21},"2075-11-06",{"name":50,"class":51},{"id":631,"slug":632,"hasResults":12,"nctId":633,"briefTitle":634,"officialTitle":635,"acronym":4,"eligibilityCriteria":636,"healthyVolunteers":60,"sex":637,"minAge":61,"maxAge":409,"enrollmentInfo":638,"targetDuration":4,"studyType":22,"phases":640,"briefSummary":641,"conditions":642,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":644,"lastUpdatePostDateStruct":645,"startDateStruct":647,"completionDateStruct":649,"leadSponsor":650,"locationsCount":82},"100571658","effect-of-resveratrol-supplementation-on-exercise-performance-and-recovery-100571658","NCT06723119","Effect of Resveratrol Supplementation on Exercise Performance and Recovery","The Effects of Resveratrol Supplementation on Functional and Systemic Markers of Muscle Damage and Cardiovascular Function in Response to a Damaging Isoinertial Squat Protocol","Inclusion Criteria:\n\n* • Male between the ages of 18-40 years old\n\n  * Healthy, and ready for physical activity as determined by the PAR-Q+, and MHQ.\n  * Participants will be required to be recreationally active (defined according to ACSM standards of at least 150 minutes exercise per week).\n  * Participants will be required to have been actively resistance training for a minimum of 6 months as defined by 3 resistance training sessions per week with at least one lower body session.\n  * Participants must be willing to abstain from the consumption of bananas of non-steroidal anti-inflammatory drugs (NSAIDs) for the duration of their enrollment in study.\n  * Participants must be willing to abstain from dietary supplementation that are viewed by study investigators to confound the outcomes of the study (e.g., Creatine). Those currently supplementing must be willing to undergo a 28-day washout prior to beginning study procedures.\n  * Participants must be consuming \\\u003C300 mg·day-1 (Equivalent to 3 cups of coffee per day or 2 16oz cans of Redbull) and willing to keep their caffeine consumption consistent throughout the duration of the study.\n  * Participants will be required to have access to the online MyFitnessPal application either via cellphone or computer and be willing to download and maintain the application for the duration of the study.\n  * Free from previous or current lower body injuries that are viewed by the investigators to potentially limit ability of the participant to perform the assessments.\n  * Willing to abstain from lower body resistance training for the 14 days preceding ET1 and ET2\n\nExclusion Criteria:\n\n* • Individual does not provide consent to participate in this study.\n\n  * Inability to perform physical exercise (determined by MHQ, and PAR Q+). That is Answering \"Yes\" to any question on the PAR-Q +, or having a pre-existing condition such as musculoskeletal injury, back pain, chronic pain etc. that the investigative team perceives will prevent a participant from safely completing the protocol.\n  * Not currently participating in at least 150 minutes of physical activity per week.\n  * Not currently resistance trained (as defined within the inclusion criteria)\n  * Currently taking any performance-enhancing drug (determined from health and activity questionnaire)\n  * Currently taking a nutritional supplement known to improve physical performance and not willing refrain form the consumption of the supplement for at least 28-days prior to beginning study procedures.\n  * Regularly taking any type of prescription or over-the-counter medication deemed to affect performance, or having any chronic illnesses, which require medical care.\n  * Have used nicotine or tobacco at any time within the last three months.\n  * Report consuming bananas or NSAIDS at any time during your enrollment in the study.\n  * Report daily caffeine consumption \\>300 mg·day-1\n  * Report any lower extremity muscle soreness for visits ET1 and ET2\n  * Previous or current lower body injuries viewed by the investigators to potentially limit the ability of the participant to perform the assessments.\n  * Inability or unwillingness to consume the provided standardized snacks and meals in their entirety.\n  * Inability or unwillingness to adhere to the diet restrictions of the study.\n  * Have a food allergy to either of the two provided energy bars.\n  * Inability or unwillingness to report all food and beverage consumption during the two 5-day dietary log periods.","MALE",{"count":639,"type":21},20,[24],"To examine the effects of once daily supplementation with 500mg VeriSperse® resveratrol (VRES) for 17 days on muscle function, delayed onset muscle soreness, systemic concentrations of muscular damage markers and markers of oxidative stress in resistance trained young adult males following a damaging isoinertial squat protocol (ISP).",[643],"Effect of Resveratrol on Performance and Recovery","2024-12-04",{"date":646,"type":44},"2024-12-09",{"date":648,"type":44},"2024-10-01",{"date":471,"type":21},{"name":50,"class":51},""]