[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Deusto\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":158},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,76,103,131],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100636645","multidimensional-study-of-dyspnea-at-rest-during-exertion-self-induced-through-a-virtual-reality-scenario-and-its-placebo-effect-in-patients-with-copd-and-control-subjects-100636645",false,"NCT07568379","Multidimensional Study of Dyspnea at Rest, During Exertion, Self-induced Through a Virtual Reality Scenario, and Its Placebo Effect in Patients With COPD and Control Subjects.","DisVir","Inclusion Criteria:\n\nCOPD:\n\n* Diagnosed COPD (FEV1\u002FFVC \\\u003C 0.7 post-bronchodilator)\n* GOLD stage 2-4\n* Clinically stable\n* Signed informed consent\n\nHealthy subjects:\n\n* Normal pulmonary function\n* No chronic diseases\n* Non-smoker or long-term ex-smoker\n\nExclusion Criteria:\n\nCOPD patients:\n\n* Severe cardiac, neurological, or psychiatric disease\n* Other respiratory diseases\n* Recent exacerbation\n* Use of ventilatory support (except CPAP)\n\nHeatlhy subjects:\n\n* Respiratory symptoms\n* Recent infections\n* Medication affecting respiratory function\n* Substance abuse",true,"ALL","18 Years",{"count":20,"type":21},80,"ESTIMATED","5 Days","OBSERVATIONAL","This quasi-experimental laboratory study aims to describe and compare the multidimensional experience of dyspnea at rest and during exertion in patients with chronic obstructive pulmonary disease (COPD) and healthy controls. The study integrates neurophysiological, somatosensory, and psychological assessments, including prefrontal cortex activity (fNIRS), quantitative sensory testing (QST), and immersive virtual reality (VR) scenarios.\n\nAdditionally, the study evaluates the modulation of dyspnea perception through expectation mechanisms and placebo intervention using high-flow nasal cannula (HFNC). The ultimate goal is to better understand the multidimensional and neurocognitive mechanisms underlying dyspnea.",[26],"COPD (Chronic Obstructive Pulmonary Disease)",[28,29,30,31,32,33],"COPD","Dyspnea","Virtual reality","fNRIS","QST","Respiratory function","NOT_YET_RECRUITING","2026-04-30",{"date":37,"type":38},"2026-05-05","ACTUAL",{"date":40,"type":21},"2026-04",{"date":42,"type":21},"2028-01",{"name":44,"class":45},"University of Deusto","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},"100630570","concomitant-use-of-radiotherapy-and-integrated-exercise---lung-cancer-100630570","NCT07489391","Concomitant Use of Radiotherapy and Integrated Exercise - Lung Cancer","Effect of an Integrated Exercise Program Concomitant With Radiotherapy on Functional Capacity in Patients With Lung Cancer","Inclusion Criteria:\n\n* Histological diagnosis of non-small cell lung cancer (NSCLC) at stage II-III (locally advanced), unresectable\u002Finoperable.\n* Candidate for radical radiotherapy with concomitant chemotherapy, with or without maintenance Durvalumab.\n* ECOG performance status ≤2 (or Karnofsky index ≥60).\n* Ability to communicate adequately with the research team and to complete questionnaires and functional tests.\n* Signed written informed consent after receiving detailed information about the study.\n\nExclusion Criteria:\n\n* Decompensated cardiorespiratory comorbidities that contraindicate moderate-intensity physical exercise:\n\n  * New York Heart Association (NYHA) class III-IV congestive heart failure or unstable angina.\n  * Recent myocardial infarction (\\\u003C6 months) or uncontrolled arrhythmias.\n  * Very severe chronic obstructive pulmonary disease (COPD) GOLD IV with recent exacerbations, permanent home oxygen therapy, or severe pulmonary hypertension.\n* Severe physical or neurological limitations that prevent exercise.\n* Absolute medical contraindications to inspiratory muscle training: unresolved pneumothorax, recent thoracic surgery (\\\u003C4 weeks), or active hemoptysis.\n* Refusal or inability to understand\u002Ffollow the program instructions (e.g., severe cognitive impairment, insurmountable language barrier).",{"count":55,"type":21},10,"INTERVENTIONAL",[58],"NA","Study objective and procedures\n\nThe objective of CURIE-LC is to evaluate the feasibility (i.e., whether it is possible and safe) of carrying out a comprehensive exercise program during combined radiotherapy and chemotherapy in patients with lung cancer. The study will assess whether patients can adhere to the exercise program while receiving oncologic treatment and will explore its effects on physical fitness and quality of life.\n\nWhat does participation involve?\n\nIf participants choose to take part, they will join a supervised exercise program conducted throughout the chemoradiotherapy treatment. The program includes three main components, tailored to the individuals' abilities:\n\nInspiratory breathing exercise: training with a specialized device to strengthen the breathing muscles and improve lung capacity.\n\nAerobic exercise: moderate-intensity aerobic activity (e.g., treadmill walking or stationary cycling) several days per week to improve endurance and cardiovascular health.\n\nStrength training: muscle-strengthening exercises (e.g., light weights or resistance bands) twice per week to maintain or increase arm and leg strength.\n\nA physiotherapist or other trained professional will guide the participant at all times to ensure exercises are performed safely and appropriately. Sessions will last approximately 20 to 60 minutes and will be coordinated with the radiotherapy\u002Fchemotherapy schedule so as not to interfere with the treatment.\n\nIn addition to the exercise sessions, participants will undergo physical assessments and complete questionnaires at several time points. Before starting and at the end of the program, the investigagtors will measure functional capacity using the 6-minute walk test (6MWT) and assess respiratory muscle strength using maximal inspiratory and expiratory pressures (PImax and PEmax). Handgrip strength will also be measured. Participants will complete questionnaires about health status, fatigue, mood, and quality of life. These evaluations will help determine the impact of exercise during treatment.\n\nThe exercise program will last for the duration of the treatment, approximately 7 to 9 weeks, with a short-term follow-up after treatment ends. Overall, participation involves attending the scheduled weekly exercise sessions during treatment, plus several evaluation visits (before, during, at the end of the program, and a few months later). Exact timing and frequency will be explained and planned according to the individual situation, aiming to minimize disruption to daily routine.",[61,62,63],"Non Small Cell Lung Cancer","Radiation Therapy Patient","Stage II\u002FIII",[65,66,67],"Lung Cancer","Exercise","Radiochemotherapy","RECRUITING",{"date":70,"type":38},"2026-05-06",{"date":40,"type":21},{"date":73,"type":21},"2026-12",{"name":44,"class":45},2,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":16,"sex":17,"minAge":83,"maxAge":18,"enrollmentInfo":84,"targetDuration":4,"studyType":56,"phases":86,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":46},"100609262","wise-intervention-for-reducing-aggressive-behaviors-and-promoting-prosocial-behaviors-toward-lgb-tnb-individuals-100609262","NCT07212283","Wise Intervention for Reducing Aggressive Behaviors and Promoting Prosocial Behaviors Toward LGB-TNB Individuals","LGB-TNB","Inclusion Criteria:\n\n* Informed consent by the adolescents and their families.\n* To be fluent in Spanish and\u002For Euskera.\n\nExclusion Criteria:\n\n* Lack of permission by families and the adolescent.\n* Lack of understanding of the instructions.","14 Years",{"count":85,"type":21},1000,[58],"This study evaluates the effectiveness of a wise Intervention to reduce aggressive behaviors and promote prosocial behaviors toward LGB-TNB individuals among Spanish adolescents. Half of the participants will receive the experimental intervention, while the other half will receive a control intervention.",[89,90],"Aggression","Adolescence",[90,92,89,93,94],"LGBTQ","Prosocial Behavior","Wise Intervention","2026-04-27",{"date":97,"type":38},"2026-05-01",{"date":99,"type":38},"2025-09-18",{"date":101,"type":21},"2026-06",{"name":44,"class":45},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":56,"phases":113,"briefSummary":114,"conditions":115,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":46},"100606693","psychosocial-teleassistance-programme-for-adults-with-spina-bifida-100606693","NCT07178873","Psychosocial Teleassistance Programme for Adults With Spina Bifida","Effects of a Psychosocial Teleassistance Programme for Adults With Spina Bifida","Inclusion Criteria:\n\n* To be diagnosed with spina bifida by a specialist.\n* Being between 18 and 75 years old.\n* Having their informed consent or the informed consent of their legal guardians.\n* Having Spanish as one of their main languages.\n* Having access to a computer (with a camera, microphone and speakers integrated) and Internet connection to take part in the videoconferences.\n\nExclusion Criteria:\n\n* Age that is inconsistent with the established range.\n* The presence of any comorbid diagnosis or sensory deficit that would impede the effective execution of the intervention's activities.","75 Years",{"count":112,"type":21},35,[58],"This clinical trial assesses the effect of a telecare psychosocial intervention designed for adults with spina bifida. The intervention consists of 10 weekly 1.5-hour group sessions, followed by two 3-month follow-up sessions. Each group will consist of 6 to 7 individuals. The intervention is aimed at strengthening aspects of self-concept, self-esteem, social skills and aims at a reduction of symptomatology and a general improvement of psychological well-being.",[116,117,118,119,120,121,122],"Spina Bifida","Self Esteem","Quality of Life (QOL)","Self Concept","Anxiety","Depression","Interpersonal Needs","2025-12-02",{"date":125,"type":38},"2025-12-10",{"date":127,"type":38},"2024-06-25",{"date":129,"type":21},"2027-01",{"name":44,"class":45},{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":138,"enrollmentInfo":139,"targetDuration":4,"studyType":56,"phases":141,"briefSummary":142,"conditions":143,"keywords":147,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":46},"100521420","predictors-of-response-to-manual-physiotherapy-using-somatosensory-profiles-in-patients-with-cervicobrachial-pain-100521420","NCT06069362","Predictors of Response to Manual Physiotherapy Using Somatosensory Profiles in Patients With Cervicobrachial Pain","Prediction of Response to Manual Physiotherapy Using Somatosensory Profiles in Patients With Cervicobrachial Pain","Inclusion Criteria:\n\n* Subjects with unilateral cervicobrachial pain\n\nExclusion Criteria:\n\n* Signs of severe disease, cervical myelopathy, tumour, rheumatic diseases or a neurological pathology of central origin.\n* Cervicobrachial pain of traumatic origin or as a result of whiplash.\n* Previous surgical intervention of the cervical spine.","80 Years",{"count":140,"type":21},91,[58],"The goal of this clinical trial is to investigate about the characteristics that predict response to physiotherapy treatment in patients with nerve related neck arm pain. The main question to answer is whether there is a subgroup that responds better to physiotherapy treatment.\n\nParticipants will be assessed for clinical and neurophysiological characteristics prior to treatment. Afterwards they will receive 6 sessions of manual physiotherapy treatment along with home nerve gliding exercises once a week. Baseline measurements will be taken again after treatment to know if there have been any changes.",[144,145,146],"Cervical Radicular Pain","Cervical Radiculopathy","Cervical Pain",[148,149],"Cervicobrachial pain","Nerve related neck arm pain","2025-03-25",{"date":152,"type":38},"2025-03-26",{"date":154,"type":38},"2023-04-20",{"date":156,"type":21},"2025-07-20",{"name":44,"class":45},""]