[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Fujairah\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":82},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100615241","postoperative-pain-after-pulpotomy-in-children-using-calcium-silicate-cements-with-and-without-laser-therapy-100615241",false,"NCT07290049","Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy","Evaluation of Postoperative Pain After Pulpotomy Using Calcium Silicate Cements in Permanent Molars With and Without Laser Biomodulation: A Randomized Clinical Trial","Inclusion Criteria:\n\nPatients between 9 and 14 years of age. Must have a two-rooted mandibular molar tooth (lower back tooth). The tooth must be diagnosed with symptomatic irreversible pulpitis (a painful, inflamed nerve).\n\nThe tooth must be considered restorable (can be fixed with a filling or crown). Patient and\u002For guardian must be able to understand and sign the informed consent form.\n\nThe tooth must be periodontally healthy, with no mobility, and not painful to tapping or pressing.\n\nExclusion Criteria:\n\nTeeth with immature root tips. Teeth that are not restorable (severely damaged or decayed). Bleeding from the tooth's nerve that cannot be controlled within 10 minutes during the procedure.\n\nPatients with significant medical conditions that could complicate dental treatment.\n\nTeeth with a dead (necrotic) nerve. Inability or unwillingness to provide informed consent. Individuals from vulnerable groups (as defined by the ethics committee).","ALL","9 Years","14 Years",{"count":20,"type":21},46,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study is for children and young adults who have a severe toothache in a permanent back molar, caused by an inflamed nerve (a condition called irreversible pulpitis). Usually, the treatment for this is a root canal, which removes the entire nerve. However, a different treatment called \"vital pulp therapy\" or \"pulpotomy\" may be an option. This simpler procedure removes only the infected part of the nerve, leaving the healthy part alive, and then seals the tooth with a special material.\n\nThe goal of our research is to see if we can make this pulpotomy procedure even more comfortable for patients afterward. We are testing two approaches:\n\nUsing a modern dental filling material called EndoCem to seal the tooth.\n\nUsing the same EndoCem material, but first applying a gentle laser to the healthy nerve tissue. This laser treatment, known as \"biomodulation,\" is thought to help calm the tissue and improve healing.\n\nPatients who join the study will be randomly assigned to one of these two treatment groups. The main thing we will measure is the level of pain after the procedure, which patients will record on a simple pain scale. We want to find out if using the laser in addition to the filling material leads to less pain and a better experience after the treatment.\n\nThis study will help dentists understand if combining this new sealing material with laser therapy can be a more effective and comfortable way to save a tooth with a severe toothache.",[27,28],"Symptomatic Irreversible Pulpitis","Symptomatic Irreversible Pulpitis (SIP)",[30,31,32,33,34,35,36,37,38,39,40],"Vital Pulp Therapy","Pulpotomy","Irreversible Pulpitis","Postoperative Pain","Calcium Silicate Cement","Bioceramic","Laser Biomodulation","Er,Cr:YSGG Laser","EndoCem","Biodentine","Randomized Controlled Trial","RECRUITING","2025-12-04",{"date":44,"type":45},"2025-12-17","ACTUAL",{"date":47,"type":45},"2025-04-24",{"date":49,"type":21},"2026-01-25",{"name":51,"class":52},"University of Fujairah","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":16,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":4,"studyType":22,"phases":66,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":53},"100584726","study-on-treatment-results-and-bone-changes-after-replanting-severely-affected-teeth---a-before-and-after-study-100584726","NCT06893107","Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.","Assessment of Treatment Outcomes and Alveolar Bone Changes Following Intentional Replantation of Hopeless Periodontally Involved Single-Rooted Teeth - A Pre-test, Post-test Interventional Study","Inclusion Criteria:\n\nPatients meeting the specified criteria will be included in the study.\n\n* The patients with American Society of Anesthesiologists physical status classification 1 and 2.\n* Radiographic bone loss of at least 50% around the targeted tooth.\n* Probing depth of at least 5 millimetres around the targeted tooth.\n* Grade III mobility (extreme mobility) of the targeted tooth according to Miller's classification.\n* Grade II mobility or less (minimal to slight increased mobility without functional impairment) of adjacent teeth.\n* Distance between the targeted tooth and adjacent teeth less than 2 millimetres.\n* Patient preference for tooth retention through intentional replantation over extraction.\n\nExclusion Criteria:\n\n* Previous history of failed IR.\n* Severe anatomical limitations in the treatment area.\n* Unwillingness to adhere to follow-up protocols",true,"18 Years","70 Years",{"count":65,"type":21},45,[24],"This research aims to evaluate the effectiveness of intentional replantation (IR) as a treatment for single-rooted teeth diagnosed as hopeless due to true periodontic lesions. The study will assess changes in alveolar bone and periodontal tissues, symptom resolution, and patient-reported outcomes (satisfaction and quality of life) following the procedure. Cone beam computed tomography (CBCT) imaging will be used to track radiographic changes at baseline and 9 months, while clinical examinations will monitor symptom resolution, including pain, swelling, and tooth mobility.\n\nThe study is a single-arm pre-test, post-test interventional design conducted at the College of Dentistry, University of Science and Technology Fujairah (new name: University of Fujairah). Participants will include adults aged 18-70 with single-rooted teeth deemed hopeless due to periodontic lesions. Participants will undergo intentional replantation, and data will be collected through clinical examinations, radiographic images, and patient questionnaires at baseline and 9 months.\n\nStatistical analysis will compare pre- and post-treatment outcomes using paired-samples t-tests or Wilcoxon signed-rank tests, depending on data normality. The study aims to provide a comprehensive evaluation of intentional replantation, contributing valuable insights into its clinical effectiveness for managing complex dental conditions.",[69],"Chronic Periodontitis",[71,72,73],"Chronic periodontitis","Periodontally compromised tooth","Intentional replantation","2025-11-20",{"date":76,"type":45},"2025-11-26",{"date":78,"type":45},"2024-03-25",{"date":80,"type":21},"2026-03-15",{"name":51,"class":52},""]