[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Göttingen\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":62},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":26,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100591591","insightrp2-registry-100591591",false,"NCT06982417","InsightRP2 Registry","InsightRP2: a Global Patient Registry for RP2-associated Retinitis Pigmentosa","Inclusion Criteria:\n\n* A molecular genetic diagnosis involving a heterozygous or hemizygous variant in RP2 and a written informed consent to participate are required for access to the registry questionnaire. Patients of all ages meeting the above criteria will be allowed to participate. As documentation will be in English and German, those who can navigate these pages will be included.\n\nExclusion Criteria:\n\n* Patients with evidence of non-RP2 molecular genetic diagnoses will be excluded. Collection of data and further analysis will not be possible without the consent of the patient or legal guardian. Patients who cannot navigate registry documentation in English or German will be excluded.","ALL",{"count":18,"type":19},200,"ESTIMATED","OBSERVATIONAL","InsightRP2 is a secure online patient registry specific to RP2-associated retinitis pigmentosa (RP). It is our goal to further the scientific understanding of this rare disease and to support research in to a gene therapy for RP2-associated RP.\n\nWe collect medical, genetic and imaging data from people affected by RP2-associated RP and will coduct a natural history study as well as image analysis studies.",[23,24,25],"RP2-associated Retinitis Pigmentosa","X-Linked Retinitis Pigmentosa (XLRP)","Retinitis Pigmentosa 2",[27],"RP2, Retinitis pigmentosa, RP2-associated Retinitis pigmentosa","RECRUITING","2025-05-13",{"date":31,"type":32},"2025-05-21","ACTUAL",{"date":34,"type":32},"2025-05-01",{"date":36,"type":19},"2045-05-01",{"name":38,"class":39},"University of Göttingen","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":40},"100526058","exercise-cmr-in-plf-lg-as-100526058","NCT06129799","Exercise CMR in (p)LF-LG AS","Exercise CMR in (Paradoxical) Low-flow Low-gradient Aortic Stenosis","Inclusion Criteria:\n\n* paradoxical or conventional severe low-flow low-gradient aortic stenosis\n\nExclusion Criteria:\n\n* CMR incapable device\n* unable to undergo 40 min scan (can not lie flat, claustrophobia)\n* renal insufficiency (eGFR \\\u003C30 ml\u002Fmin\u002F1.73m²)\n* allergy against contrast agent\n* unable to exercise in supine position","18 Years",{"count":50,"type":19},100,"Patient with paradoxical or conventional low-flow low-gradient aortic stenosis on echocardiographic assessment will undergo physiological exercise-stress CMR in addition to guideline recommended surveys prior to TAVR.",[53],"Aortic Stenosis, Severe","2023-11-09",{"date":56,"type":32},"2023-11-13",{"date":58,"type":32},"2023-11-01",{"date":60,"type":19},"2026-12-31",{"name":38,"class":39},""]