[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Graz\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":108},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100541519","muscle-tendon-pathology-and-metabolic-dysregulation-in-cp-100541519",false,"NCT06330922","Muscle-tendon Pathology and Metabolic Dysregulation in CP","Muscle-tendon Pathology, Metabolic Dysregulation and Chronic Inflammation in Adolescents and Young Adults With Moderate to Severe Spastic Cerebral Palsy","Inclusion Criteria:\n\n* spastic cerebral palsy\n* mildly, moderately or severly affected (Gross Motor Function Classification System level I-IV)\n* age range 14 - 30 years\n* ability to accept and follow verbal instructions\n* strong communication skills\n* sufficient vision (visual function that enables safe movement with reference to people and obstacles)\n* less than 15 hours of experience with the Frame Runners; healthy peers in the same age range\n\nExclusion Criteria:\n\n* other forms of cerebral palsy\n* orthopaedic surgery in the last 12 months\n* Botulinum toxin application in the last 6 months",true,"ALL","14 Years","30 Years",{"count":21,"type":22},50,"ESTIMATED","OBSERVATIONAL","The main aim of this project is to gain knowledge about the muscle-tendon pathology of moderately to severely affected young people with cerebral palsy and their risk for cardiometabolic diseases and chronic inflammation. Furthermore, it will be investigated whether there are associations between the existing pathophysiology as well as inactivity and muscle function, cardiometabolic risk factors and inflammation. Moreover, the potential of the target group for adaptation of its muscular, cardiorespiratory, and endocrine system will be investigated.\n\nThe study parameters will be determined in adolescents and young adults aged 14 to 30 years with moderate to severe spastic cerebral palsy and compared with those of their less severely affected and healthy peers (cross-sectional study). In addition, the more affected individuals will participate in a 12-week training intervention (longitudinal study) performed with special tricycles (i.e., Frame Runners).\n\nTo measure the study parameters, ultrasound, strength tests, near-infrared spectroscopy, blood analyses, and spiroergometry will be used. The fitness training will be performed two times a week for 12 weeks with the Frame Runners.",[26],"Cerebral Palsy, Spastic",[28,29,30,31,32],"Cerebral Palsy","Spasticity","Cardiorespiratory Fitness","Frame Running","Muscle","RECRUITING","2026-04-28",{"date":36,"type":37},"2026-04-29","ACTUAL",{"date":39,"type":37},"2024-03-08",{"date":41,"type":22},"2027-03-31",{"name":43,"class":44},"University of Graz","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":16,"sex":17,"minAge":19,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":45},"100572010","effect-of-biostrength-training-on-muscle-strength-and-satisfaction-in-adults-aged-30-65-100572010","NCT06727695","Effect of BioStrength Training on Muscle Strength and Satisfaction in Adults Aged 30-65","A Comparative Study of Training Effectiveness: Technogyms Biostrength Devices Vs. Conventional Strength Training Devices: a Randomized Controlled Trial","BIO-STR","Inclusion Criteria:\n\n* • Age between 30 and 65 years\n\n  * Healthy individuals without significant medical conditions\n  * Less than 6 months of prior strength training experience\n  * Willing and able to participate in a 12-week training program\n  * Capable of performing strength training exercises such as leg press and chest press\n  * Able to provide written informed consent\n\nExclusion Criteria:\n\n* • History of coronary heart disease\n\n  * History of stroke\n  * Need for changes in antihypertensive treatment within 3 months prior to study start\n  * Arthritis\n  * Pregnancy or less than three months postpartum\n  * Pain and movement restrictions\n  * Use of medications that affect muscle strength or performance (e.g., anabolic steroids, beta-2 agonists, glucocorticoids, statins, benzodiazepines, ACE inhibitors, angiotensin-II receptor blockers, diuretics)\n  * Any medical condition preventing participation in planned endurance and strength training","65 Years",{"count":56,"type":22},42,"INTERVENTIONAL",[59],"NA","This study aims to evaluate the effectiveness of Technogyms BioStrength equipment compared to traditional strength training equipment over a 12-week intervention period. The study will determine whether BioStrength machines produce more effective results in terms of muscle strength and body composition. Participants will be allocated to either the BioStrength group or the traditional training group using a minimisation technique to balance important prognostic factors such as handgrip strength, age and gender between the groups. Key measurements include maximum strength tests (10RM) for leg press and chest press, handgrip strength using a dynamometer, and body composition using bioimpedance analysis. Circumference measurements will also be taken. The study will assess whether BioStrength equipment provides superior results in muscle strength, body composition and training efficiency compared to conventional gym equipment.",[62,63,64],"Muscle Strength","Body Composition","Physical Fitness",[66,67,68,69,70,71,72,73,74,75],"Strength training","Muscle strength","Body composition","Customer satisfaction","BioStrength","Technogym","Resistance training","Fitness equipment","Handgrip strength","Randomized controlled trial","2024-12-05",{"date":78,"type":37},"2024-12-11",{"date":80,"type":37},"2024-10-08",{"date":82,"type":22},"2025-10-01",{"name":43,"class":44},{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":53,"healthyVolunteers":16,"sex":17,"minAge":19,"maxAge":54,"enrollmentInfo":91,"targetDuration":4,"studyType":57,"phases":92,"briefSummary":93,"conditions":94,"keywords":95,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":102,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":45},"100572011","comparison-of-two-biocircuit-programs-impact-on-physical-fitness-and-body-composition-in-adults-aged-30-65-100572011","NCT06727708","Comparison of Two BioCircuit Programs: Impact on Physical Fitness and Body Composition in Adults Aged 30-65","A Comparative Study of Two Biocircuit Training Programs:Tone Your Body Vs. Boost Performance on Physical Performance and Body Composition a Randomized Controlled Trial","Biocircuit",{"count":56,"type":22},[59],"This study aims to compare the effects of two BioCircuit training programmes, 'Tone Your Body' and 'Boost Performance', on physical fitness and body composition in adults aged 30-65 years. Participants will be randomized to one of the two exercise programmes and will undergo a 12-week intervention with baseline and post-intervention measurements of fitness and body composition. The study aims to determine which programme is more effective in improving overall physical fitness, muscle mass and reducing body fat.",[62,63,64],[96,66,97,68,98,99,72,100,75,101],"Circle Training","Muscle mass","Physical fitness","BioCircuit","Body fat reduction","Handgripstrength",{"date":78,"type":37},{"date":104,"type":37},"2024-10-31",{"date":106,"type":22},"2025-10-31",{"name":43,"class":44},""]