[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Guelph\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":202},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,44,73,99,131,167],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100587457","supper-heroes-examining-the-impact-of-an-online-eating-intervention-for-families-100587457",false,"NCT06928636","Supper Heroes: Examining the Impact of an Online Eating Intervention for Families","Supper Heroes: Randomized Controlled Trial to Examine the Impact of an Online Environmentally Friendly Eating Intervention for Families","Inclusion Criteria:\n\n* have at least one child 9-12 years old\n* live in Ontario, Canada\n* have access to the internet\n* can respond to English surveys\n\nExclusion Criteria:\n\n* parent(s) with prior nutrition and food education (e.g., degree in nutrition, culinary arts training)\n* families with food allergies that would prevent them from participating in the intervention (e.g., soy products, beans or lentils)\n* families who are vegetarian or vegan",true,"ALL",{"count":19,"type":20},330,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study will examine the effectiveness of the online family-based program focused on sustainable eating compared to weekly emails about environmentally friendly behaviours.",[26],"Eating Behaviors",[28,29,30],"food waste","environmentally friendly","plant-based foods","RECRUITING","2026-06-04",{"date":34,"type":35},"2026-06-08","ACTUAL",{"date":37,"type":35},"2025-07-09",{"date":39,"type":20},"2027-12",{"name":41,"class":42},"University of Guelph","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":16,"sex":17,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":43},"100568891","egg-intake-metabolic-outcomes-and-choline-levels-100568891","NCT06687122","Egg Intake, Metabolic Outcomes and Choline Levels","Additional Daily Intake of Eggs for Improving Metabolic Outcomes and Choline Levels in Individuals With Obesity: Phase I Study","Inclusion Criteria:\n\n* Male or female participant of any race or ethnicity between 30-65 (inclusive) years of age\n* BMI \\> 30 kg\u002Fm2\n* Non-smoker\n* Willing to consume 3 eggs per day for one dietary period of 4 weeks\n* Willing to avoid eggs during the rest of the study except for eggs that are provided\n* Willing to follow the study protocol including maintaining usual lifestyle during the entire study\n\nExclusion Criteria:\n\n* Age \\\u003C 30 or \\> 65 years\n* BMI \\\u003C 30 kg\u002Fm2\n* Vegans or individuals who do not consume eggs\n* Individuals who are currently pregnant or planning to become pregnant during the course of the study; or are currently breastfeeding\n* Smokers, users of recreational drugs\n* Individuals taking antibiotics or natural health products including prebiotics or probiotics","30 Years","65 Years",{"count":54,"type":20},20,[23],"The purpose of this research is to determine the effect of additional daily egg intake on metabolic phenotypes and metabolism in the context of obesity.",[58],"Obesity and Obesity-related Medical Conditions",[60,61,62,63,64],"Eggs","Liver health","Obesity","Metabolism","Gut microbiome","2026-05-09",{"date":67,"type":35},"2026-05-12",{"date":69,"type":35},"2025-01-24",{"date":71,"type":20},"2026-12",{"name":41,"class":42},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":16,"sex":17,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":21,"phases":83,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":98,"locationsCount":43},"100568309","effects-of-partial-sleep-deprivation-on-cardiac-output-during-cycling-100568309","NCT06679543","Effects of Partial Sleep Deprivation on Cardiac Output During Cycling","Inclusion Criteria:\n\n* Free of known cardiovascular or metabolic diseases or sleep disorders\n* No history of smoking (within the past 3 months)\n* Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+)\n* No prescription of chronic medications other than oral contraceptives\n* Able to abide by sleep protocols for all visits\n* Individuals who are not allergic to ultrasound gel\n* Individuals who are not pregnant\n\nExclusion Criteria:\n\n* Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders\n* Has a history of smoking (within the past 3 months)\n* Not ready to engage in physical activity as assessed by the PAR-Q+\n* Individuals prescribed chronic medications other than oral contraceptives\n* Unable to abide by sleep protocols for any testing visit\n* Allergic to ultrasound gel\n* Pregnancy","18 Years","50 Years",{"count":82,"type":20},30,[23],"The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are:\n\n* Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation?\n* Do sex differences exist?\n\nParticipants will:\n\n* Visit the lab after a night of normal sleep and a night of partial sleep deprivation.\n* Keep a daily diary of their sleep and food\u002Fbeverage intake.\n* Perform maximal and submaximal exercise on a cycle ergometer.",[86],"Sleep Deprivation",[88,89,90,91],"exercise blood pressure","cardiac output","plasma volume","sleep deprivation","2026-04-27",{"date":94,"type":35},"2026-04-28",{"date":96,"type":35},"2025-01-02",{"date":71,"type":20},{"name":41,"class":42},{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":17,"minAge":106,"maxAge":107,"enrollmentInfo":108,"targetDuration":4,"studyType":21,"phases":110,"briefSummary":111,"conditions":112,"keywords":116,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":43},"100485586","emotion-focused-family-therapy-for-parents-of-children-with-mental-health-difficulties-100485586","NCT05603000","Emotion Focused Family Therapy for Parents of Children With Mental Health Difficulties","A Randomized Controlled Trial of Emotion Focused Family Therapy for Parents of Children With Mental Health Difficulties","Inclusion Criteria:\n\n* Parent of child aged 7 to 15 years old with anxiety, depression, or behavioural challenges\n* Parent of child is willing to participate in intervention\n* Parent is living at home with the child\n\nExclusion Criteria:\n\n* Parent or child not proficient enough in speaking\u002Funderstanding English to complete measures or EFFT intervention components\n* Parent or child with a severe mental health disorder (e.g., active suicidality and psychosis) is not considered suitable for the trial intervention due to the clinical need for immediate intervention\n* Parent or child is actively receiving, or due to receive, intensive psychological intervention focused on cognitive and\u002For behavioural strategies to intervene with emotional or behavioural difficulties\n* Parent or child has any disabilities in language, speech or hearing that would interfere with their completion of the EFFT and measures\n* Parent or child are allergic to adhesive electrode gel use in some tasks (i.e., sodium chloride)","7 Years","15 Years",{"count":109,"type":20},200,[23],"Emotion Focused Family Therapy (EFFT) is a promising intervention that aims to teach parents advanced skills to support their child's development of emotion skills and increase their adaptive behaviours, potentially leading to improvements in their child's psychological functioning and family functioning more broadly.\n\nThis randomized controlled trial (RCT; EFFT vs waitlist control) will (1) test the efficacy of a 6-week group EFFT program on parent and child outcomes and (2) examine maintenance of treatment gains up to four months post-intervention.",[113,114,115],"Anxiety","Depression","Behavior Problem",[117,118,119,120,121,122],"children","parents","mental health","emotion","psychotherapy","parent-child relationship","2026-01-21",{"date":125,"type":35},"2026-01-23",{"date":127,"type":35},"2022-10-11",{"date":129,"type":20},"2027-03",{"name":41,"class":42},{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":16,"sex":139,"minAge":79,"maxAge":140,"enrollmentInfo":141,"targetDuration":4,"studyType":21,"phases":143,"briefSummary":144,"conditions":145,"keywords":149,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":43},"100597974","the-chocolate-almond-study---relating-chewing-to-satiation-and-postprandial-response-100597974","NCT07065461","The Chocolate Almond Study - Relating Chewing to Satiation and Postprandial Response","The Impact of Almond Size in a White Chocolate Matrix on Satiation, Postprandial Glycemia & Lipemia, Chewing Exertion, Eating Rate, and Product Liking: A Randomized Crossover Trial","CAS","Inclusion Criteria:\n\n* BMI between 18.5-27.9 kg\u002Fm\\^2 or waist circumference less than 88 cm\n* No known food allergies or sensitivities\n* Non-restrained eaters based on the Three Factor Eating Questionnaire\n* No history of gastrointestinal diseases that may interfere with eating behaviour or digestion\n* Not on medications that affect appetite, digestion, blood sugar regulation, saliva production, or chewing\n* Stable medication use\n* Non-smokers\n* Not gained or lost significant weight during the past 3 months\n* Regular monthly menstrual cycles\n* Not pregnant, lactating, or post-menopausal\n\nExclusion Criteria:\n\n* Diabetes or other metabolic disorders affecting glycemia and overall cardiometabolic health\n* Any food allergies, intolerance, or sensitivities\n* Any life-threatening allergy\n* Pregnant or breastfeeding\n* Participation in another clinical trial\n* Alcohol consumption more than 14 drinks per week\n* Smokers or those with a smoking history or more than 10 years\n* Regular use of recreational drugs (e.g., marijuana, ecstasy, magic mushrooms)\n* Restrained eater as defined by \\> 15 on the Three-Factor Eating Questionnaire\n* Unusual sleep patterns\n* Irregular breakfast consumption\n* Recent weight changes or intended weight loss or gain or having lost or gained \\>10% of body weight within the last 6 months\n* Using medications known to affect appetite, digestion, blood sugar regulation, lipids, or chewing (excluding oral contraceptives)\n* Experiences dry mouth, in general or due to medication side effects\n* Diagnosed with Sjogren's Syndrome (autoimmune condition linked to severe dry mouth)\n* Inability to adhere to study protocols\n* Not comfortable providing finger prick blood samples\n* Avoids consuming almonds or chocolate\n* Has temporomandibular joint disorder (TMJ)\n* Has or history or oral cancer\n* Recent dental or jaw surgery\n* Avoids eating hard foods for concerns of dental fractures or for general oral health\n* Individuals with dentures, braces, Invisalign, or other dental implants that cause difficulty chewing","FEMALE","45 Years",{"count":142,"type":20},35,[23],"The goal of this clinical trial is to relate chewing behaviours to food intake and postprandial response for a texturally complex food matrix (almonds in white chocolate) in healthy young females. The main questions it aims to answer are:\n\n* Does the presence or preparation of almonds (whole versus chopped) influence satiation, i.e., the amount consumed at an ad libitum meal?\n* What is the correlation between chewing behaviour, satiation, and changes in postprandial glucose, triacylglycerols, and satiety ratings? Participants will attend the research centre fasted on three occasions to consume an ad libitum meal, complete questionnaires, and provide fasting and postprandial finger prick blood samples.",[146,147,148],"Satiation, Satiety","Postprandial Glycemia","Postprandial Lipemia",[150,151,152,153,154,155,156,157,158],"Almonds","Particle size","Satiation","Satiety","Postprandial glycemia","Postprandial lipemia","White chocolate","Food matrix","chewing exertion","2025-07-03",{"date":161,"type":35},"2025-07-15",{"date":163,"type":35},"2025-06-01",{"date":165,"type":20},"2026-05",{"name":41,"class":42},{"id":168,"slug":169,"hasResults":11,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":4,"eligibilityCriteria":173,"healthyVolunteers":11,"sex":17,"minAge":174,"maxAge":107,"enrollmentInfo":175,"targetDuration":4,"studyType":21,"phases":177,"briefSummary":178,"conditions":179,"keywords":188,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":194,"startDateStruct":196,"completionDateStruct":198,"leadSponsor":200,"locationsCount":201},"100488223","big-feelings-a-study-on-childrens-emotions-in-therapy-100488223","NCT05637320","Big Feelings: A Study on Children's Emotions in Therapy","Biobehavioural Regulation of Negative Emotion as a Transdiagnostic Mechanism of Children's Psychotherapy","Inclusion Criteria:\n\n* Child must be between the ages of 8 and 15 years old and have English proficiency\n* Parents must be over the age of 18 and have English proficiency\n* Must be seeking psychosocial treatment for concerns related to anxiety, depression, or disruptive behaviours\n\nExclusion Criteria:\n\n* Child has low cognitive functioning that would prevent active participation in research tasks\n* Child reports active suicidality that requiring acute care or hospital intervention\n* Child meets criteria for psychosis, schizophrenia spectrum disorders, eating disorders or autism spectrum disorders\n* Child does not assent to participate in the study","8 Years",{"count":176,"type":20},202,[23],"The goal of this clinical trial is to learn about how psychotherapy works for children and adolescents aged 8 - 15 with anxiety, depression, trauma, or disruptive behaviour. The main question it aims to answer is:\n\n• Is the biobehavioural regulation of negative emotion a transdiagnostic mechanism of treatment response in psychotherapy for children with anxiety, depression, trauma and\u002For disruptive behaviour?\n\nChildren and their parents will be randomly assigned to an evidence-based, transdiagnostic treatment (the Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems; MATCH-ADTC) or a waitlist control condition. Participants in both groups will complete a baseline assessment, weekly measures consisting of brief symptom scales and medication tracking, and quarterly assessments every 3 months. Following the intervention\u002Fwaitlist period, our team will conduct post-test assessments. All assessments, except for the weekly surveys, will consist of symptom scales, clinical interviews, experimental tasks and physiological measures.",[180,181,182,183,184,185,186,187],"Anxiety Disorders","Depressive Disorder","Mood Disorders","Conduct Disorder","Oppositional Defiant Disorder","Regulation, Emotion","Child Behavior Disorders","Trauma and Stressor Related Disorders",[189,190,191,192],"Child psychotherapy","Emotion regulation","Physiology","Mechanism of change","2025-01-27",{"date":195,"type":35},"2025-01-29",{"date":197,"type":35},"2022-10-01",{"date":199,"type":20},"2027-12-31",{"name":41,"class":42},2,""]