[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Jazan\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":125},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,46,75,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100605711","the-effect-of-mobilization-on-inflammatory-biomarkers-in-patients-with-knee-osteoarthritis-100605711",false,"NCT07166068","The Effect of Mobilization on Inflammatory Biomarkers in Patients With Knee Osteoarthritis.","The Effect of Mobilization With Movement Versus Sham Mobilization on Inflammatory Biomarkers in Patients With Knee Osteoarthritis.","Inclusion Criteria:\n\n* Clinical diagnosis of unilateral or bilateral knee osteoarthritis (OA) according to the criteria of the American College of Rheumatology\n* Age ≥ 18 years\n* Kellgren-Lawrence grade 2 or 3 knee OA\n* Pain intensity \\> 3 on a visual analogue scale (VAS)\n* Body mass index (BMI) between 18.5 and 30 kg\u002Fm²\n\nExclusion Criteria:\n\n* Knee or lower limb surgery within the last six months.\n* Significant joint disorders (e.g., rheumatoid arthritis, gout, or other inflammatory arthritis).\n* Recent significant acute infections.\n* Contraindications to mobilization with movement.\n* Current or recent use systemic glucocorticoids, intra-articular glucocorticoid injections or intra-articular hyaluronic acid injections.","ALL","18 Years",{"count":19,"type":20},40,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study is designed to investigate whether a hands-on therapy called Mobilization with Movement (MWM) can reduce pain and inflammation in individuals with knee osteoarthritis (OA). The investigators will compare MWM to a sham treatment that resembles mobilization but does not involve the specific therapeutic movements. Both groups will also receive standard care, including exercise and education about managing knee OA.\n\nA total of 40 adults (aged 18 years and older) with moderate to severe knee OA will be enrolled. Participants will be randomly assigned to either the MWM group or the sham group. Each intervention will be delivered twice per week over a four-week period.\n\nOutcomes will include measures of inflammation obtained from blood samples, self-reported pain levels, and assessments of knee function before and after the intervention period. It is hypothesized that individuals allocated to the MWM group will demonstrate reduced inflammation and pain compared with those in the sham group. The findings of this study may help clarify the potential role of MWM as a treatment option for knee OA.",[26],"Knee Osteoarthritis",[28,29,30,31,32],"Knee OA","MWM","Manual Therapy","CRP","ESR","RECRUITING","2025-12-08",{"date":36,"type":37},"2025-12-09","ACTUAL",{"date":39,"type":37},"2025-09-20",{"date":41,"type":20},"2026-04-20",{"name":43,"class":44},"University of Jazan","OTHER_GOV",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":72,"leadSponsor":74,"locationsCount":45},"100569756","the-effect-of-mirror-therapy-on-upper-extremity-motor-function-in-stroke-rehabilitation-100569756","NCT06698380","The Effect of Mirror Therapy on Upper Extremity Motor Function in Stroke Rehabilitation","MT","Inclusion Criteria:\n\n* Duration of stroke more than six months\n* Subjects of chronic stroke with left or right hemiplegia.\n* Genders of male and female with age ranging between forty-five to sixty-five years.\n* MMSE scores greater than 23 out of 30.\n* Scored one or one plus on MAS on all muscles of the affected upper limb.\n* Have normal visual perception.\n* Able to follow oral commands.\n\nExclusion Criteria:\n\n* Unable to follow visual and oral commands.\n* Unilateral neglect.\n* Cognitive impairments (MMSE scores less than 24 out of 30), or language deficits.\n* Any other neurological disorders and recent surgeries.\n* Previous exposure to MT.","45 Years","65 Years",{"count":56,"type":20},38,[23],"The study aimed to determine the effect of mirror therapy versus conventional physical therapy treatment in improving upper extremity impairments and motor function among chronic hemiplegic subjects.\n\nResearch Objectives:\n\n1. To discover the effectiveness of conventional physical therapy treatment on improving upper limb motor function among chronic hemiplegic subjects.\n2. To find out the effect of mirror therapy along with conventional physical therapy treatment on improving upper limb motor function among chronic hemiplegic subjects.\n3. To find out the effectiveness of mirror therapy combined with conventional physical therapy treatment versus conventional physical therapy treatment alone on improving upper extremity motor function among chronic hemiplegic subjects.",[60,61,62],"Stroke","Chronic Stroke Patients","Hemiplegia",[64,62,65,66,67],"storke","mirror therapy","upper extremity","motor function","2024-11-18",{"date":70,"type":37},"2024-11-21",{"date":68,"type":37},{"date":73,"type":20},"2025-07-30",{"name":43,"class":44},{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":82,"targetDuration":4,"studyType":21,"phases":84,"briefSummary":85,"conditions":86,"keywords":87,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":45},"100569309","the-effect-of-modified-constraint-induced-movement-therapy-on-upper-extremity-function-in-stroke-rehabilitation-100569309","NCT06692569","The Effect of Modified Constraint Induced Movement Therapy on Upper Extremity Function in Stroke Rehabilitation","mCIMT","Inclusion Criteria:\n\n* Right or left-sided chronic hemiplegic patients.\n* Onset of stroke More than six months.\n* Age between 45 to 65 years of both genders.\n* Mini-Mental State Examination - Scored more than 24\u002F30.\n* Modified Ashworth Scale for spasticity 1 or 1+.\n* Have at least 20° wrist active extension and at least 10° of metacarpophalangeal active extension of the paretic upper extremity.\n* Have at least grade 2\u002F5 of muscle power on upper extremity especially in wrist extensors.\n* Have normal visual perception.\n* With no other neurological disorders.\n\nExclusion Criteria:\n\n* Unable to follow visual and oral commands.\n* Unilateral neglect.\n* Severe cognitive, or language deficits.",{"count":83,"type":20},34,[23],"The purpose of the study is to determine the effect of Modified Constraint-Induced Movement Therapy and trunk restraint contrasted with conventional physical therapy treatment on improving upper extremity function, balance, and quality of life among chronic hemiplegic patients.\n\n* To find out the effectiveness of conventional physical therapy treatment on improving upper extremity function, balance, and quality of life among chronic hemiplegic patients.\n* To find out the effectiveness of modified constraint induced movement therapy (mCIMT) and trunk restraint along with conventional physical therapy treatment on improving upper extremity function, balance, and quality of life among chronic hemiplegic patients.\n* To find out the effectiveness of modified constraint induced movement therapy (mCIMT) and trunk restraint combined with conventional physical therapy treatment versus conventional physical therapy treatment alone on improving upper extremity function, balance, and quality of life among chronic hemiplegic patients.",[60,62,61],[88,89,90,91,92,93],"stroke","hemiplegia","constraint induced movement therapy","modified constraint induced movement therapy","trunk restrain","upper extremity motor function","2024-11-14",{"date":68,"type":37},{"date":97,"type":37},"2024-11-12",{"date":99,"type":20},"2025-07-13",{"name":43,"class":44},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":109,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":115,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":45},"100569117","the-effect-of-motor-relearning-program-on-functional-mobility-in-stroke-rehabilitation-100569117","NCT06690073","The Effect of Motor Relearning Program on Functional Mobility in Stroke Rehabilitation.","The Effect of Motor Relearning Program on Functional Mobility in Stroke Rehabilitation","MRP","Inclusion criteria: The following subjects were included:\n\n* Right or left-sided chronic hemiplegic subjects.\n* More than six months after the onset of stroke.\n* Age group between 45-65 years of both genders.\n* Scored minimally 24\u002F30 on the Mini-Mental State Exam (MMSE).\n* Motor assessment scale of sitting to standing section.\n* Having normal visual perception.\n* Able to follow verbal commands.\n\nExclusion criteria: The following subjects were excluded:\n\n* Less than six months after the onset of stroke.\n* Unable to follow visual and oral commands.\n* The age group is below 45 years and more than 65 years.\n* Unilateral neglect.\n* Cognitive impairments (MMSE scores less than 24\u002F30), or language deficits.\n* Any other neurological disorders and recent surgeries.\n* Previous exposure to MRP.",{"count":110,"type":20},32,[23],"1. To find out the effectiveness of conventional physiotherapy on improving functional mobility of lower extremity among chronic hemiplegic subjects.\n2. To find out the effcctiveness of motor relearning program along with conventional physical therapy treatment on improving functional mobility of lower extremity among chronic hemiplegic subjects.\n3. To find out the effectiveness of motor relearning program along with conventional physical therapy treatment over conventional physical therapy on improving functional mobility of lower extremity among chronic hemiplegic subjects.",[60,61,114,62],"Chronic Stroke Survivors",[60,62,116,117],"Functional mobility","motor relearning program",{"date":119,"type":37},"2024-11-15",{"date":121,"type":37},"2024-11-04",{"date":123,"type":20},"2025-06-30",{"name":43,"class":44},""]