[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Lahore\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":547},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,20,0,[8,43,75,110,131,160,184,204,237,258,284,318,348,373,393,416,439,467,492,521],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100644970","comparative-effects-of-myofascial-release-and-instrument-assisted-soft-tissue-moblization-in-pregnant-women-with-plantar-fasciitis-100644970",false,"NCT07676058","Comparative Effects of Myofascial Release and Instrument Assisted Soft Tissue Moblization in Pregnant Women With Plantar Fasciitis","MFR-IASM-PF","Inclusion Criteria:\n\n* Pregnant women aged 20-40 years.\n* In the second and third trimester of pregnancy (gestational weeks 12-34).\n* Clinically diagnosed with plantar fasciitis, with symptoms of heel pain at the medial calcaneal insertion of the plantar fascia.\n* The pain is most intense with the first few steps in the morning or after prolonged rest. Positive findings from a Windlass test or palpation-provoked pain indicating plantar fasciitis.\n\nExclusion Criteria:\n\n* Known foot fractures or significant foot deformities.\n* Systemic inflammatory diseases (e.g., rheumatoid arthritis) that may affect tissue healing and response to therapy.\n* Active obstetric complications that contraindicate physiotherapy.\n* Recent corticosteroid injections to the heel (\\\u003C6 months prior).\n* Inability or unwillingness to comply with follow-up visits or the intervention protocol.","FEMALE","20 Years","40 Years",{"count":20,"type":21},44,"ESTIMATED","INTERVENTIONAL",[24],"NA","Plantar fasciitis is a common musculoskeletal disorder characterized by heel pain and functional limitations, which may become more pronounced during pregnancy due to weight gain, hormonal changes, and altered biomechanics. Conservative physiotherapy interventions are commonly used to manage symptoms; however, evidence regarding the comparative effectiveness of different manual therapy techniques in pregnant women remains limited.\n\nThis randomized clinical trial aims to compare the effects of Myofascial Release (MFR) and Instrument-Assisted Soft Tissue Mobilization (IASTM) on pain intensity and foot function in pregnant women diagnosed with plantar fasciitis. A total of 44 pregnant women aged 20-40 years in their second or third trimester will be recruited and randomly allocated into two treatment groups. Both groups will receive baseline treatment consisting of therapeutic ultrasound, gastrocnemius and soleus stretching exercises, tibialis anterior strengthening, and a home exercise program. In addition, Group A will receive Myofascial Release, while Group B will receive Instrument-Assisted Soft Tissue Mobilization.\n\nThe intervention will be delivered over a period of four weeks, with three supervised sessions per week. Pain intensity will be assessed using the Numerical Pain Rating Scale (NPRS), while foot-related pain, disability, and functional limitations will be measured using the Foot Function Index (FFI). Outcomes will be evaluated at baseline and after completion of the intervention.\n\nThe findings of this study are expected to provide evidence regarding the most effective manual therapy approach for reducing pain and improving functional outcomes in pregnant women suffering from plantar fasciitis.",[27],"Plantar Fasciitis",[27,29,30],"Myofascial Release","Instrument-Assisted Soft Tissue Mobilization","RECRUITING","2026-06-23",{"date":34,"type":35},"2026-06-30","ACTUAL",{"date":34,"type":21},{"date":38,"type":21},"2026-07-31",{"name":40,"class":41},"University of Lahore","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":42},"100634965","photobiomodulation-in-chronic-fatigue-syndrome-100634965","NCT07546539","Photobiomodulation in Chronic Fatigue Syndrome","The Role of Photobiomodulation in Patients With Chronic Fatigue Syndrome","Inclusion Criteria\n\n* Age 18-60 years\n* Diagnosis of a CFS according to the 2015 Institute of Medicine criteria\n* Fatigue Severity Scale (FSS) score ≥ 4\n* Ability to understand study procedures and provide informed consent\n\nExclusion Criteria\n\n* Comorbid psychiatric conditions (e.g., major depression, schizophrenia)\n* Current use of corticosteroids or immunomodulators\n* Known photosensitivity or dermatologic contraindications to LLLT\n* Participation in structured exercise programs more than twice weekly\n* Diagnosed malignancy or active infection -Not willing to be the part of study -","ALL","18 Years","60 Years",{"count":54,"type":21},40,[24],"The goal of this clinical trial is to evaluate whether photobiomodulation therapy (low-level laser therapy) can reduce fatigue and improve quality of life in patients with chronic fatigue syndrome (CFS). The study will include adults aged 18-60 years diagnosed with chronic fatigue syndrome.\n\nThe main questions it aims to answer are:\n\nDoes photobiomodulation therapy significantly reduce fatigue levels as measured by the Fatigue Severity Scale (FSS) and Multidimensional Fatigue Inventory (MFI-20)? Does photobiomodulation therapy improve pain, functional capacity, sleep quality, and psychological well-being in patients with chronic fatigue syndrome?\n\nResearchers will compare the low-level laser therapy group with a placebo (sham laser) group to determine whether photobiomodulation therapy leads to greater improvements in fatigue, pain, and overall quality of life.\n\nParticipants will:\n\nReceive either active low-level laser therapy or placebo treatment three times per week for eight weeks Undergo assessments of fatigue, pain, functional capacity, quality of life, sleep quality, and psychological well-being at baseline and follow-up intervals (3, 6, and 12 months)",[58,59],"Chronic Fatigue Syndrome (CFS)","Quality of Life",[61,62,63,64,65,66],"PHOTOBIOMODULATION","LOW-LEVEL LASER THERAPY","Chronic Fatigue Syndrome","Rehabilitation","Physiotherapy","Fatigue","2026-06-21",{"date":69,"type":35},"2026-06-24",{"date":71,"type":35},"2026-06-15",{"date":73,"type":21},"2026-09",{"name":40,"class":41},{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":50,"minAge":18,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":4},"100639218","home-and-clinic-rehabilitation-in-subacute-stroke-100639218","NCT07613554","Home and Clinic Rehabilitation in Subacute Stroke","Comparison of Clinical and Scheduled Home-based Rehabilitation in Patients With Sub-acute Stroke.","ADLS PAC HBP","Inclusion Criteria:\n\nAge 40-50 years old Male and female Patients having stroke 3 months to 6 months prior to enrollment Able to comprehend and adhere to instructions Grade 1+ spasticity on Modified Ashworth Scale Modified Rankin Scale score of 3-4 with ability to maintain sitting balance for at least 1 hour\n\nExclusion Criteria:\n\nMyocardial infarction Other neurological deficits leading to disability Contractures Severe dysphasia and cognitive impairment Need for further surgery or medical care","50 Years",{"count":85,"type":21},72,[24],"The goal of this clinical trial is to learn if adding scheduled home-based rehabilitation to clinic-based rehabilitation improves walking ability and daily activities in people aged 40 to 50 with sub-acute stroke. The main questions it aims to answer are:\n\n* Does adding home exercises improve walking ability in people with sub-acute stroke?\n* Does adding home exercises improve the ability to do daily activities in people with sub-acute stroke? Researchers will compare clinic-based rehabilitation plus home-based rehabilitation to clinic-based rehabilitation alone to see if adding home exercises leads to better recovery after stroke.\n\nParticipants will:\n\n* Attend physical therapy at the hospital 3 days per week for 12 weeks\n* Do walking practice, balance training, and leg exercises at the clinic\n* Do home exercises including marching, step-ups, sit-to-stand, and balance exercises on non-clinic days (home exercise group only)\n* Track home exercises using a weekly logbook\n* Be tested at the start and after 12 weeks",[89],"Sub-acute Stroke",[91,92,93,94,95,96,97,98,99,100],"stroke rehabilitation","sub-acute stroke","home-based rehabilitation","clinical-based rehabilitation","functional capacity","balance","gait training","timed up and go test","Hemiplegia","Activities of daily living","NOT_YET_RECRUITING","2026-05-21",{"date":104,"type":35},"2026-05-29",{"date":106,"type":21},"2026-06",{"date":108,"type":21},"2027-03",{"name":40,"class":41},{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":50,"minAge":83,"maxAge":117,"enrollmentInfo":118,"targetDuration":4,"studyType":22,"phases":120,"briefSummary":121,"conditions":122,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":42},"100638315","trunk-control-exercises-and-mirror-therapy-on-balance-and-posture-in-parkinsons-disease-100638315","NCT07610031","Trunk Control Exercises and Mirror Therapy on Balance and Posture in Parkinson's Disease","Effects of Trunk Control Exercises and Mirror Therapy on Balance and Posture in Patients With Parkinson's Disease","Inclusion Criteria:\n\n* • 50-70 age(Bomasang-Layno et al., 2015)\n\n  * Both genders (Bomasang-Layno et al., 2015)\n  * Patient with grade 1,2,3 Parkinsonism (according to Hoehn and Yahr scale)\n  * Patient taking fixed dose of medicines\n  * No cognitive impairment (according to Mini-Mental scale 24-30 scoring) (Capecci et al., 2014)\n  * The patient was able to get out of chairs and beds without assistance (Hoffmann et al., 2016).\n  * Individuals without significant dyskinesias or \"on-off\" periods.(Lötzke et al., 2015)\n\nExclusion Criteria:\n\n* • Patient having any recent episode of epilepsy(Bomasang-Layno et al., 2015)\n\n  * Patient has had any recent trauma. (Hong et al., 2009)\n  * Individuals free from chronic diseases such as unstable cardiovascular disease that could compromise their safety during training or testing (Hoffmann et al., 2016).","70 Years",{"count":119,"type":21},36,[24],"Parkinson's disease (PD) is movement disorder of the nervous system that worsens over time. As nerve cells (neurons) in parts of the brain weaken or are damaged or die, people may begin to notice problems with movement, tremor, stiffness in the limbs or the trunk of the body, or impaired balance. As these symptoms become more obvious, people may have difficulty walking, talking, or completing other simple tasks. Not everyone with one or more of these symptoms has PD, as the symptoms appear in other diseases as well.\n\nBoth non-modifiable (age, gender) and modifiable risk factors such as occupation, exposure to pesticides, and depression have an association with PD. Several studies have suggested that Parkinson disease is more common in men. The MT mechanism is based on the concept of visual illusion. The movement of the non-paretic part in front of the mirror (reflective side) is perceived as that of the paretic body part (hidden beside the mirror). MT allows an individual to have an experience of normal movement, even for the severely paralyzed limb. In addition, wherever other rehabilitation methods fail to induce normal movements without any compensation, MT may act as a foundation step for further motor therapy. The perception of movement illusion, a neuropsychological phenomenon may induce neural activation of the lesioned brain and enhance associated motor recovery. Therefore the aim of this study is to compare the effects of truck control exercise program and mirror therapy on balance and postural instability in patients with Parkinson's disease.",[123],"Parkinson s Disease",{"date":125,"type":35},"2026-05-27",{"date":127,"type":35},"2024-12-22",{"date":129,"type":21},"2026-06-20",{"name":40,"class":41},{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":11,"sex":50,"minAge":18,"maxAge":52,"enrollmentInfo":139,"targetDuration":4,"studyType":22,"phases":141,"briefSummary":142,"conditions":143,"keywords":146,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":42},"100637221","effect-of-high-intensity-laser-therapy-on-femoral-cartilage-in-knee-osteoarthritis-100637221","NCT07584603","Effect of High-Intensity Laser Therapy on Femoral Cartilage in Knee Osteoarthritis","The Role of High-intensity Laser Therapy on Femoral Cartilage Thickness in Patients With Knee Osteoarthritis","HILT-KOA","Inclusion Criteria:\n\n* Male and female participants aged 40-60 years.\n* Diagnosed with knee osteoarthritis (Kellgren-Lawrence grade II or III).\n* Knee pain for at least 3 months.\n* Visual Analogue Scale (VAS) score ≥ 3.\n* Willing to provide written informed consent and comply with treatment and follow-up schedule.\n\nExclusion Criteria:\n\n* History of knee surgery or traumatic knee injury.\n* Inflammatory arthritis (e.g., gout, psoriatic arthritis).\n* History of cancer or psychiatric illness.\n* Cognitive disorders (e.g., Parkinson's disease, Alzheimer's disease).\n* Severe comorbidities limiting exercise (e.g., severe COPD, heart failure, cerebrovascular event).\n* Hip or ankle joint disability.\n* Intra-articular knee injection within the past 3 months.",{"count":140,"type":21},58,[24],"This clinical trial will evaluate the effects of High-Intensity Laser Therapy (HILT) on femoral cartilage thickness and other clinical outcomes in people with knee osteoarthritis. Participants aged 40 to 60 years with grade II or III knee osteoarthritis will be randomly assigned to receive either HILT plus conventional physiotherapy or conventional physiotherapy alone. Both groups will receive 12 treatment sessions on alternate days for 4 weeks. The study will assess changes in cartilage thickness using ultrasound, as well as improvements in pain, knee movement, muscle strength, and daily function. Findings from this research may help improve physiotherapy treatment strategies for patients with knee osteoarthritis.",[144,145],"Osteoarthritis (OA) of the Knee","Osteoarthitis",[147,148,149,150,151],"High Intensity Laser Therapy","Knee Osteoarthritis","Femoral Cartilage Thickness","High Level Laser Therapy","Osteoarthritis","2026-05-07",{"date":154,"type":35},"2026-05-13",{"date":156,"type":21},"2026-07-01",{"date":158,"type":21},"2027-05-10",{"name":40,"class":41},{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":164,"acronym":4,"eligibilityCriteria":165,"healthyVolunteers":166,"sex":50,"minAge":167,"maxAge":168,"enrollmentInfo":169,"targetDuration":4,"studyType":22,"phases":171,"briefSummary":172,"conditions":173,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":42},"100634019","hepatoprotective-effects-of-reishi-mushroom--ganoderma-lucidum-among-metabolic-dysfunction-associated-fatty-liver-disease-patients-100634019","NCT07534241","Hepatoprotective Effects of Reishi Mushroom- (Ganoderma Lucidum) Among Metabolic Dysfunction-associated Fatty Liver Disease Patients","Inclusion Criteria:\n\n* Adults aged 35-65 years\n* BMI between 18.5 and 30 kg\u002Fm².\n* Complete Blood Count test ranges, WBC \\\u003C 4,000-11,000 cells\u002FµL, RBC Men \\\u003C 4.5-6.0 \u002F Women 4.0-5.5 million\u002FµL, Hemoglobin: Men \\\u003C 13.5-17.5 \u002F Women 12.0-15.5 g\u002FdL, Platelets \\\u003C 150,000-450,000 cells\u002FµL.\n* Lipid profile test markers (elevated LDL, total cholesterol, or triglycerides less than 150mg\u002FdL high 200-499mg\u002FdL and 500 mg\u002FdL are above high.\n* Liver function test markers, ALT \\> 56 U\u002FL, AST\\>40 U\u002FL, ALP\\>147 UL.\n* Inflammatory markers: CRP \\>3 mg\u002FL, - IL-6 ≥3 pg\u002FmL, TNF-α ≥8 pg\u002FmL.\n* Elevated blood sugar levels, or hyperglycemia, refer to a typically above 126 mg\u002FdL, fasting or 200 mg\u002FdL post-meal.\n\nExclusion Criteria:\n\n* ● Diagnosed with severe cardiovascular disease, liver failure, or renal impairment.\n\n  * Pregnant or lactating women.\n  * Individuals currently on statins, ezetimibe, PCSK9 inhibitors, or any other lipid-lowering therapy.\n  * Allergic to mushrooms.\n  * Diagnosed with celiac disease or other chronic gastrointestinal disorders (e.g., Crohn's disease, ulcerative colitis).\n  * History of malignancy.\n  * Participation in another clinical trial within the last 3 months.",true,"35 Years","65 Years",{"count":170,"type":21},102,[24],"This 12-week RCT investigates the hepatoprotective and immunomodulatory effects of Ganoderma lucidum combined with a probiotic-rich diet in adults with MAFLD, assessing liver enzymes, lipid profile, inflammation, gut microbiota, and oxidative stress.\n\nFindings are expected to show dose-dependent improvements in hepatic fat, insulin resistance, and inflammatory markers, potentially reducing reliance on pharmacotherapy in",[174,175],"Lipid Profile","Liver Biomarkers","2026-04-09",{"date":178,"type":35},"2026-04-16",{"date":180,"type":35},"2025-10-02",{"date":182,"type":21},"2026-04-15",{"name":40,"class":41},{"id":185,"slug":186,"hasResults":11,"nctId":187,"briefTitle":188,"officialTitle":188,"acronym":4,"eligibilityCriteria":189,"healthyVolunteers":11,"sex":50,"minAge":17,"maxAge":52,"enrollmentInfo":190,"targetDuration":4,"studyType":22,"phases":192,"briefSummary":193,"conditions":194,"keywords":4,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":4},"100629907","scapular-muscle-strengthening-combined-with-core-stabilization-exercises-in-telephone-operators-with-neck-pain-100629907","NCT07480772","Scapular Muscle Strengthening Combined With Core Stabilization Exercises in Telephone Operators With Neck Pain","Inclusion Criteria:\n\n* 1\\. Aged between 20 and 60 years(Kang, Im, \\& Kim, 2021) 2. Both male and female(Hetaimish et al., 2024) 3. Sitting job during an 8-hour shift and worked telephone, and documents.(Tabanfar, Sobhani, Safari Variani, \\& Varmazyar, 2023) 4. Employed 6 months ago 5. The patients included in this study if they have CVA equal or less than 50(Abd El-Azeim et al., 2022) 6. Neck pain with mild neck disability (NDI score 5-15)(Pawaria, Sudhan, \\& Kalra, 2019) 7. A score of 4-7 for the Visual Analog Scale (VAS)(Kang et al., 2021)\n\nExclusion Criteria:\n\n* 1\\. History of traumatic cervical spine injuries ,Inflammatory arthropathy 2. Infectious spondylitis, severe osteoporosis, cervical disc protrusion, cervical spine fractures or dislocations, previous cervical surgery, and intractable migraines.(Tian et al., 2025a) 3. intermittent neck pain, transient neck pain or any radiation of the pain to the upper extremity (neurological origin of the pain)",{"count":191,"type":21},90,[24],"Scapular muscle strengthening combined with core stabilization exercises is an effective intervention for reducing neck pain in telephone operators. Prolonged sitting, forward head posture, and repetitive upper-limb use in this population often lead to scapular dyskinesis and poor trunk control, increasing cervical spine stress. Strengthening the scapular stabilizers (such as the middle and lower trapezius and serratus anterior) improves shoulder girdle alignment and reduces overload on cervical muscles. When combined with core stabilization exercises, which enhance trunk stability and postural control, overall biomechanical efficiency is improved. This combined approach has been shown to decrease pain intensity, improve neck function, enhance posture, and reduce work-related musculoskeletal strain in telephone operators with neck pain.",[195],"Work-related Neck Pain","2026-03-17",{"date":198,"type":35},"2026-03-20",{"date":200,"type":21},"2026-02",{"date":202,"type":21},"2026-12",{"name":40,"class":41},{"id":205,"slug":206,"hasResults":11,"nctId":207,"briefTitle":208,"officialTitle":209,"acronym":4,"eligibilityCriteria":210,"healthyVolunteers":11,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":211,"targetDuration":4,"studyType":22,"phases":213,"briefSummary":214,"conditions":215,"keywords":218,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":228,"lastUpdatePostDateStruct":229,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":235,"locationsCount":236},"100627252","pharmacist-led-interventions-in-psychiatric-patients-100627252","NCT07446218","Pharmacist-led Interventions in Psychiatric Patients","Impact of Pharmacist-Led Interventions in Psychiatric Patients on Second Generation Antipsychotics","Inclusion Criteria:\n\n* Adults aged 18-60 years.\n* Diagnosed with schizophrenia, bipolar disorder, or major depressive disorder.\n* Currently prescribed a second-generation antipsychotic for \\\u003C 2 months.\n* Willing to participate in lifestyle and counseling sessions.\n\nExclusion Criteria:\n\n* Patients with severe medical comorbidities.\n* Pregnant or breastfeeding women.\n* Patients receiving only first-generation antipsychotics.\n* Patients taking more than three antipsychotics.\n* Patients using combination of first and second generation antipsychotics.\n* Individuals with cognitive impairment.\n* Patients with type 2 diabetes mellitus.",{"count":212,"type":21},148,[24],"The goal of this intervention study is to examine the impact of pharmacist-led interventions in psychiatric patients initiating second-generation antipsychotic treatment. The primary purpose is to assess the impact of intervention on antipsychotic induced metabolic outcomes, such as weight gain and other cardiometabolic risk markers, in patients aged 18 to 60 years who have been diagnosed with chronic mental disorder. Participants will be assigned to either the intervention or the control group. The intervention group will receive educational interventions from the pharmacist at baseline, after 4 weeks, 8 weeks, and 12 weeks along with the standard therapy prescribed by the psychiatrist. On the other hand, the control group will receive only the standard therapy with no intervention from the pharmacist.",[216,217],"Mental Disorders","Metabolic Syndrome",[219,220,221,222,223,224,225,226,227],"severe mental illness","chronic mental disorder","atypical antipsychotics","intervention study","RCT","Pakistan","metabolic syndrome","second generation antipsychotics","educational intervention","2026-02-25",{"date":230,"type":35},"2026-03-03",{"date":232,"type":21},"2026-03-01",{"date":234,"type":21},"2026-05-31",{"name":40,"class":41},2,{"id":238,"slug":239,"hasResults":11,"nctId":240,"briefTitle":241,"officialTitle":242,"acronym":4,"eligibilityCriteria":243,"healthyVolunteers":11,"sex":50,"minAge":244,"maxAge":245,"enrollmentInfo":246,"targetDuration":4,"studyType":22,"phases":247,"briefSummary":248,"conditions":249,"keywords":4,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":251,"lastUpdatePostDateStruct":252,"startDateStruct":254,"completionDateStruct":255,"leadSponsor":257,"locationsCount":4},"100625254","task-oriented-training-versus-group-circuit-training-in-children-with-quadriplegic-cerebral-palsy-100625254","NCT07420244","Task-oriented Training Versus Group Circuit Training in Children With Quadriplegic Cerebral Palsy","Task-oriented Training Versus Group Circuit Training in Children With Quadriplegic Cerebral","Inclusion Criteria:\n\n* Children diagnosed with spastic quadriplegic cerebral palsy.\n* Age between 7 and 12 years.\n* Gross Motor Function Classification System (GMFCS) level II or III.\n* Both genders.\n* Lower limb spasticity graded between 1 and 1+ on the Modified Ashworth Scale.\n* Ability to understand and follow simple instructions.\n* No serious or recurrent medical complications.\n\nExclusion Criteria:\n\n* Presence of fixed orthopedic deformities affecting balance or movement.\n* Visual, auditory, vestibular, or perceptual deficits.\n* History of seizures or epilepsy.\n* Orthopedic surgery or botulinum toxin injections within the past 6 months.\n* Participation in other structured rehabilitation programs during the study period.\n* Presence of neuromuscular disorders other than cerebral palsy.","7 Years","12 Years",{"count":119,"type":21},[24],"Cerebral palsy is a common neurodevelopmental disorder that affects movement, posture, and functional abilities in children. This randomized controlled trial focuses on comparing the effects of task-oriented circuit training and group circuit training on functional performance and functional capacity in children with quadriplegic cerebral palsy. Outcomes will be measured using the Gross Motor Function Measure (GMFM-88) and the Activities Scale for Kids-Capability version (ASK-C). The findings of this study may help identify effective rehabilitation strategies for improving functional outcomes in children with cerebral palsy.",[250],"Quadriplegic Cerebral Palsy","2026-02-11",{"date":253,"type":35},"2026-02-19",{"date":232,"type":21},{"date":256,"type":21},"2026-09-01",{"name":40,"class":41},{"id":259,"slug":260,"hasResults":11,"nctId":261,"briefTitle":262,"officialTitle":263,"acronym":264,"eligibilityCriteria":265,"healthyVolunteers":166,"sex":50,"minAge":168,"maxAge":4,"enrollmentInfo":266,"targetDuration":4,"studyType":22,"phases":268,"briefSummary":269,"conditions":270,"keywords":272,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":276,"lastUpdatePostDateStruct":277,"startDateStruct":279,"completionDateStruct":281,"leadSponsor":283,"locationsCount":4},"100620573","progressive-resistance-exercise-versus-functional-training-in-elderly-with-risk-of-fall-100620573","NCT07359378","Progressive Resistance Exercise Versus Functional Training in Elderly With Risk of Fall.","Progressive Resistance Exercises Versus Functional Training in Elderly With Risk of Fall.","PRE","Inclusion Criteria:\n\n* Both Males and Female Patients\n* Patients Age 65 years or above\n* Participants with intact cognitive function or mild cognitive impairment who can follow instructions and provide informed consent\n* Individuals medically cleared by their physician to engage in moderate-intensity physical activities, with no unstable medical conditions that could impede participation\n* Participants willing to commit to an 8-week intervention program (3 sessions per week) and attend follow-ups as required.\n\nExclusion Criteria:\n\n* Elderly individuals who are non-ambulatory or unable to perform basic mobility tasks, such as standing or walking independently, even with assistive devices.\n* Uncontrolled medical conditions such as uncontrolled hypertension, unstable angina, or severe arrhythmias.\n* Participants with severe musculoskeletal conditions that significantly limit mobility or exercise participation (e.g., severe arthritis, recent fractures, or joint replacements within the last 6 months).\n* Presence of acute pain or injury that may worsen with physical activity. Individuals with progressive neurological conditions such as Parkinson's disease, 15 stroke with severe residual deficits, or multiple sclerosis that impede safe participation in physical activities.",{"count":267,"type":21},39,[24],"Study Design: Randomized Clinical Trial Objective: To find the effects of Progressive Resistance Exercises for balance and risk of falls in elderly population.\n\nTo find the effects of Functional Training for balance and risk of falls in elderly population.\n\nTo compare the effects of Progressive Resistance Exercises and Functional Training for balance and risk of falls in elderly population.\n\nInclusion Criteria:\n\nBoth Males and Female Patients Patients Age 65 years or above Participants with intact cognitive function or mild cognitive impairment who can follow instructions and provide informed consent Individuals medically cleared by their physician to engage in moderate-intensity physical activities, with no unstable medical conditions that could impede participation Participants willing to commit to an 8-week intervention program (3 sessions per week) and attend follow-ups as required.\n\nExclusion Criteria:\n\nElderly individuals who are non-ambulatory or unable to perform basic mobility tasks, such as standing or walking independently, even with assistive devices.\n\nUncontrolled medical conditions such as uncontrolled hypertension, unstable angina, or severe arrhythmias.\n\nParticipants with severe musculoskeletal conditions that significantly limit mobility or exercise participation (e.g., severe arthritis, recent fractures, or joint replacements within the last 6 months).\n\nPresence of acute pain or injury that may worsen with physical activity. Individuals with progressive neurological conditions such as Parkinson's disease, stroke with severe residual deficits, or multiple sclerosis that impede safe participation in physical activities.\n\nGroup 1: Progressive Resistance Exercises Participants in the Progressive Resistance Training (PRT) group will engage in a structured exercise program designed to progressively increase muscle strength, balance, and overall physical function.\n\nGroup 2: Functional Training Participants in the Functional Training (FT) group will engage in exercises that mimic daily activities to improve balance, strength, mobility, and functional independence.",[271],"Elderly",[273,274,275],"fall","progressive resistive","functional training","2026-01-29",{"date":278,"type":35},"2026-01-30",{"date":280,"type":21},"2026-01-01",{"date":282,"type":21},"2026-03-10",{"name":40,"class":41},{"id":285,"slug":286,"hasResults":11,"nctId":287,"briefTitle":288,"officialTitle":289,"acronym":290,"eligibilityCriteria":291,"healthyVolunteers":11,"sex":50,"minAge":18,"maxAge":292,"enrollmentInfo":293,"targetDuration":4,"studyType":22,"phases":295,"briefSummary":296,"conditions":297,"keywords":304,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":310,"lastUpdatePostDateStruct":311,"startDateStruct":313,"completionDateStruct":315,"leadSponsor":317,"locationsCount":236},"100611771","therapeutic-effects-of-instrument-assisted-versus-sound-assisted-soft-tissue-mobilization-in-chronic-non-specific-low-back-pain-100611771","NCT07244913","Therapeutic Effects of Instrument-assisted Versus Sound-assisted Soft Tissue Mobilization in Chronic Non-specific Low Back Pain","Therapeutic Effects of Instrument-assisted Versus Sound-assisted Soft Tissue Mobilization Among Patients With Chronic Non-specific Low Back Pain","IASTM VS SASTM","Inclusion Criteria:\n\n* Pain between the inferior gluteal folds and the costal margins.\n* Pain with a duration of a minimum of 24 weeks.\n* Moderate to severe pain (\\>3) was measured using the Numeric Pain Rating Scale.\n* Straight Leg raise Limited (hamstring tightness)\n\nExclusion Criteria:\n\n* Pain in lower back with radiating\u002Freferring but limited to proximal legs\n* Pain for the last 03 months and at least half of the days in the last six months.\n* Presence of neurological problem\u002Fdeficit\u002Fdisease (e.g., nerve root compression, motor deficit, paresthesia) and lower limb symptoms.\n* Presence of disease like Infection, tumors, spondylolisthesis grade II or higher, vertebral fractures, identifiable cause like endometriosis\n* Medicine like immunosuppression or steroid medication;\n* Spinal deformities\n* History of severe rheumatic, orthopedic, or cardiovascular disease in the last three months before study participation.\n* Previously diagnosed Osteoporosis\n* SIJ dysfunction is evaluated by a positive compression test.\n* BMI over 35.\n* Skin allergy or hypersensitivity that can lead to skin irritation due to IASTM\u002FSASTM tools.","55 Years",{"count":294,"type":21},60,[24],"Chronic low back pain (CLBP) is the most common medical problem observed among musculoskeletal pain and spinal pain problems. It can reduce the movements due to muscular imbalances, decreased activity of daily living, and effects on health-related quality of life. It is the major cause of activity limitation, work absence, and reported clinical issues. Most of the cases of low back pain remained undiagnosed and received only symptomatic management.",[298,299,300,301,302,303],"Chronic Non-Specific Low Back Pain","Pelvic Obliquity","Hamstring Flexibility","Physical Function","Disability","Lumbar Flexibility",[305,306,307,308,309,299,301,300],"IASTM","SASTM","CPGS","Disability Index","Flexibility","2025-12-30",{"date":312,"type":35},"2026-01-02",{"date":314,"type":35},"2025-12-23",{"date":316,"type":21},"2026-06-04",{"name":40,"class":41},{"id":319,"slug":320,"hasResults":11,"nctId":321,"briefTitle":322,"officialTitle":323,"acronym":4,"eligibilityCriteria":324,"healthyVolunteers":11,"sex":50,"minAge":325,"maxAge":168,"enrollmentInfo":326,"targetDuration":4,"studyType":22,"phases":328,"briefSummary":329,"conditions":330,"keywords":333,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":340,"lastUpdatePostDateStruct":341,"startDateStruct":343,"completionDateStruct":345,"leadSponsor":347,"locationsCount":42},"100611774","effects-of-vojta-therapy-on-posture-and-trunk-control-100611774","NCT07244952","Effects of Vojta Therapy on Posture and Trunk Control","Effects of Vojta Therapy on Posture and Trunk Control in Patients With Sub-acute Stroke","Inclusion Criteria:\n\n* Age 45-65 years\n* Both males and females\n* First time subacute stroke (7 days post stroke to 3 months)\n* Brunnstrom stage 1,2\n* A confirmed CT scan for subacute ischemic stroke\n* A hemiplegia with score of ≤2 of medical research council scale for muscle strength of the arm (MRCS)\n* Premorbid modified Rankin scale score ≤ 3\n* Stroke patient who can achieve supported standing\n* Patients having NIHSS score 16-20 will be included\n* Patient who can achieve sitting for 30 seconds\n\nExclusion Criteria:\n\n* Severe cognitive impairments that can hinder rehabilitation\n* Limitations in communication due to aphasia\n* Altered consciousness or dementia (Epple et al., 2020b)\n* Patients suffering from postural hypotension","45 Years",{"count":327,"type":21},62,[24],"Vojta therapy that is reflex locomotion therapy is a neurophysiological rehabilitation approach that stimulates specific \"reflex zones\" on the body to activate global, innate movement patterns. In stroke rehabilitation, it is used to improve postural control, trunk stability, and functional movement by engaging automatic motor responses. Vojta stimulation can activate motor cortical and subcortical areas as well as postural muscles. Pose estimation will be used to analyze human motion in stroke patients. The study will identify if there is significant difference in the comparative effects of Vojta therapy in addition to routine physical therapy on posture, trunk control and upper extremity motor function in sub-acute stroke patients",[331,332],"Stroke","Stroke Ischemic",[331,334,335,336,337,338,339],"cerebral vascular accident","Vojta therapy","pose estimation","posture control","trunk control","upper extremity function","2025-11-22",{"date":342,"type":35},"2025-11-28",{"date":344,"type":35},"2025-11-15",{"date":346,"type":21},"2026-08-30",{"name":40,"class":41},{"id":349,"slug":350,"hasResults":11,"nctId":351,"briefTitle":352,"officialTitle":353,"acronym":4,"eligibilityCriteria":354,"healthyVolunteers":11,"sex":50,"minAge":51,"maxAge":168,"enrollmentInfo":355,"targetDuration":4,"studyType":22,"phases":356,"briefSummary":357,"conditions":358,"keywords":360,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":366,"lastUpdatePostDateStruct":367,"startDateStruct":369,"completionDateStruct":371,"leadSponsor":372,"locationsCount":4},"100605369","comparing-low-level-laser-and-muscle-energy-techniques-in-diabetic-frozen-shoulder-100605369","NCT07161622","Comparing Low-Level Laser and Muscle Energy Techniques in Diabetic Frozen Shoulder","Effects of Low Level Laser Therapy Versus Muscle Energy Techniques Among Diabetic Patients With Frozen Shoulder","Inclusion Criteria:\n\n* Eligible participants were male and female individuals aged 18 to 65 years with a verified diagnosis of type 2 diabetes mellitus and clinical manifestations of frozen shoulder for at least three months. The diagnosis was determined by limited glenohumeral joint mobility, characterised by a decrease of ≥20° in a minimum of three active movements: flexion \\<144°, abduction \\<120°, and external rotation \\<72°. Cases of both unilateral and bilateral nature were incorporated.\n\nExclusion Criteria:\n\n* The exclusion criteria included a history of traumatic shoulder injury or prior surgery; neurological involvement, such as brachial plexus injury or cervical radiculopathy; rotator cuff tears or other ligamentous pathologies; tumours or malignancies affecting the shoulder; and corticosteroid injection within the preceding three months",{"count":119,"type":21},[24],"The current study is to evaluate the comparative effects of low-level laser therapy and muscle energy technique on pain, range of motion, and functional results in diabetic patients with frozen shoulder. This research aims to enhance the existing data on managing diabetes-related musculoskeletal issues by assessing the comparative advantages of various therapies, therefore assisting physicians in choosing appropriate, patient-centred rehabilitation procedures.",[359],"Frozen Shoulder",[361,362,363,364,365],"Frozen shoulder","Low-Level Laser Therapy","Muscle Energy Technique,","Range of Motion","Diabetes","2025-09-17",{"date":368,"type":35},"2025-09-18",{"date":370,"type":21},"2025-10",{"date":200,"type":21},{"name":40,"class":41},{"id":374,"slug":375,"hasResults":11,"nctId":376,"briefTitle":377,"officialTitle":378,"acronym":4,"eligibilityCriteria":379,"healthyVolunteers":11,"sex":50,"minAge":51,"maxAge":167,"enrollmentInfo":380,"targetDuration":4,"studyType":22,"phases":382,"briefSummary":383,"conditions":384,"keywords":4,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":366,"lastUpdatePostDateStruct":386,"startDateStruct":388,"completionDateStruct":390,"leadSponsor":392,"locationsCount":4},"100607499","comparing-muscle-energy-technique-and-bowen-therapy-for-pain-movement-and-disability-in-text-neck-syndrome-100607499","NCT07189351","Comparing Muscle Energy Technique and Bowen Therapy for Pain, Movement, and Disability in Text Neck Syndrome","Comparative Effects of Muscle Energy Technique and Bowen Therapy on Pain, Range of Motion, and Functional Disability in Patients With Text Neck Syndrome","Inclusion Criteria:\n\n* • Age 18-35 years\n\n  * Both genders\n  * Using smart phone more than 4 hours per day and pain from last 6 months.\n  * Neck disability index greater than 10. (Seemal et al., 2022)\n\nExclusion Criteria:\n\n* • Subjects who had signs of recent surgery.\n\n  * Whiplash injury or open wounds.\n  * Cervical spine pathologies like radiculopathies, disc herniation, spondylolisthesis, sensory changes in neck region..\n  * Deformities like torticollis.\n  * Any inflammatory or malignant type of pain.",{"count":381,"type":21},78,[24],"This study compared the effects of Muscle Energy Technique and Bowen Therapy on patients with Text Neck Syndrome's pain, function ROM, and posture. Today, text neck syndrome is a growing issue. The majority of us experience this unpleasant condition to some extent. There is no study that has compared the effects of muscle energy technique and Bowen therapy, although they can both be quite effective in helping individuals with text neck syndrome reduce their discomfort, improve their range of motion, and improve their functional impairment. So, the goal of this study was to compare the two treatments' results in order to determine whether one was a better method for treating text neck syndrome patients' discomfort by enhancing range of motion and functional impairment.",[385],"Text Neck Syndrome",{"date":387,"type":35},"2025-09-23",{"date":389,"type":21},"2025-09",{"date":391,"type":21},"2025-12",{"name":40,"class":41},{"id":394,"slug":395,"hasResults":11,"nctId":396,"briefTitle":397,"officialTitle":397,"acronym":398,"eligibilityCriteria":399,"healthyVolunteers":11,"sex":50,"minAge":51,"maxAge":168,"enrollmentInfo":400,"targetDuration":4,"studyType":22,"phases":402,"briefSummary":403,"conditions":404,"keywords":406,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":408,"lastUpdatePostDateStruct":409,"startDateStruct":411,"completionDateStruct":413,"leadSponsor":415,"locationsCount":42},"100605491","therapeutic-efficacy-of-different-wavelengths-of-low-level-laser-therapy-in-the-treatment-of-cervicogenic-headache-100605491","NCT07163208","Therapeutic Efficacy of Different Wavelengths of Low-Level Laser Therapy in the Treatment of Cervicogenic Headache","WELL","Inclusion Criteria:\n\n* Patients aged 18-65 years diagnosed with cervicogenic headache based on the International Classification of Headache Disorders (ICHD-3) criteria.\n* Persistent headaches for at least 3 months.\n* No previous exposure to low-level laser therapy (LLLT).\n\nExclusion Criteria:\n\n* Patients with other primary headache disorders (e.g., migraine, tension-type headache).\n* History of cervical spine surgery.\n* Pregnant or lactating women.\n* Patients with a history of photosensitivity or taking photosensitizing medications.",{"count":401,"type":21},150,[24],"This study tests if low-level laser therapy (LLLT) with different light wavelengths can help people with cervicogenic headache, a type of headache caused by neck problems. Adults aged 18-65 with this headache for at least 3 months will try one of three LLLT treatments (675nm, 820nm, or a mix of wavelengths) along with regular physical therapy like stretching and exercises. The study will check pain levels, how often headaches happen, neck movement, disability, and quality of life over 6 weeks, with follow-ups at 3 and 6 months. the investigators want to find the best LLLT option to reduce headache symptoms safely.",[405],"Cervicogenic Headache",[405,362,407],"Neck Pain","2025-09-15",{"date":410,"type":35},"2025-09-19",{"date":412,"type":35},"2024-09-05",{"date":414,"type":21},"2025-10-05",{"name":40,"class":41},{"id":417,"slug":418,"hasResults":11,"nctId":419,"briefTitle":420,"officialTitle":420,"acronym":4,"eligibilityCriteria":421,"healthyVolunteers":11,"sex":50,"minAge":422,"maxAge":245,"enrollmentInfo":423,"targetDuration":4,"studyType":22,"phases":425,"briefSummary":426,"conditions":427,"keywords":429,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":433,"lastUpdatePostDateStruct":434,"startDateStruct":436,"completionDateStruct":437,"leadSponsor":438,"locationsCount":4},"100605051","dual-task-training-with-vestibular-stimulation-in-children-with-diplegic-cerebral-palsy-100605051","NCT07157488","Dual Task Training With Vestibular Stimulation in Children With Diplegic Cerebral Palsy","Inclusion Criteria:\n\n\\- Diagnosis of diplegic cerebral palsy (confirmed by physician\u002Ftherapist).\n\nAge between 6-12 years.\n\nGross Motor Function Classification System (GMFCS) levels II-III.\n\nAbility to walk with or without assistive devices.\n\nStable medical condition for the past 6 months.\n\nParental\u002Fguardian consent to participate.\n\nExclusion Criteria:\n\n* History of recent orthopedic surgery (within the past 6 months).\n\nBotulinum toxin injections within the past 6 months.\n\nSevere uncontrolled epilepsy or other uncontrolled medical conditions.\n\nSevere cognitive impairment preventing ability to follow instructions.\n\nSignificant visual, auditory, or vestibular disorders unrelated to cerebral palsy.\n\nParticipation in another interventional clinical study within the last 3 months.","6 Years",{"count":424,"type":21},54,[24],"Dual task training enhances gross motor function, reduce fatigue and minimize cognitive motor interference in children with diplegic cerebral palsy by promoting neuroplasticity and improving dual task processing. Vestibular stimulation improve balance triggering the vestibulospinal reflex, which play a key role in maintaining posture and reducing the risk of fall. Integrating dual task training with vestibular stimulation can provide a more holistic rehabilitation strategy by enhancing balance and posture stability through improved vestibular system activation, supporting motor and cognitive coordination by challenging the brain to handle tasks concurrently, and boosting functional mobility by mimicking everyday situations that require divided attention. This RCT evaluates its effectiveness in optimizing motor-cognitive integration, functional mobility and endurance compared to conventional motor training approaches.",[428],"Diplegic Cerebral Palsy",[430,431,432],"Diplegic cerebral palsy","Dual task training","Vestibular stimulation","2025-08-27",{"date":435,"type":35},"2025-09-05",{"date":389,"type":21},{"date":391,"type":21},{"name":40,"class":41},{"id":440,"slug":441,"hasResults":11,"nctId":442,"briefTitle":443,"officialTitle":444,"acronym":4,"eligibilityCriteria":445,"healthyVolunteers":11,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":446,"targetDuration":4,"studyType":22,"phases":447,"briefSummary":448,"conditions":449,"keywords":451,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":460,"lastUpdatePostDateStruct":461,"startDateStruct":463,"completionDateStruct":465,"leadSponsor":466,"locationsCount":42},"100601392","custom-insole-with-transcutaneous-electrical-nerve-stimulation-on-clinical-outcomes-of-diabetic-foot-ulcers-100601392","NCT07109895","Custom Insole With Transcutaneous Electrical Nerve Stimulation on Clinical Outcomes of Diabetic Foot Ulcers","Effects of a Polyethene-Poron Custom Insole Combined With Transcutaneous Electrical Nerve Stimulation on Clinical Outcomes in Diabetic Foot Ulcers","Inclusion Criteria:\n\n1. 18-60 years old with type 1 and 2 diabetes\n2. Both Males and Females\n3. Having Foot ulcers in Grade 1 and Grade 2 according to the Wagner Classification\n\nExclusion Criteria:\n\n1. History of amputation (proximal to the trans-metatarsal joint)\n2. Active or inactive Charcot foot\n3. Non-constructible peripheral vascular disease secondary to arteriosclerosis (AS)\n4. Leg length discrepancy\n5. The presence of any allergic condition of the skin,\n6. Chronic consumption of opioids,\n7. Use of a cardiac pacemaker,\n8. Major bone operation,\n9. Neurological illness, such as a vestibular disorder with a history of dizziness 10. Mental disorders, which might interfere with the assessment process\n\n11\\. Dementia or impaired cognitive function",{"count":54,"type":21},[24],"Diabetic foot ulcers (DFUs) are one of the serious complications of diabetes, typically resulting from neuropathy or peripheral arterial disease, and can often lead to amputation. It affects approximately 6.3% of people with diabetes globally. In Pakistan, the overall prevalence of DFUs is 16.83%, with a slightly higher rate in females. Diabetic foot ulcers are the main reason for lower extremity amputation (LEA) with non-traumatic origin, hospitalization, healthcare costs, and mortality.",[450],"Diabetic Foot Ulcer",[452,450,453,454,455,456,457,458,459,365],"Functional Disability","Transcutaneous Electrical Nerve Stimulation","Customized Insole","Pain","Dynamic Balance","Risk of Fall","Wound Size","Wound Depth","2025-08-11",{"date":462,"type":35},"2025-08-14",{"date":464,"type":35},"2025-08-10",{"date":278,"type":21},{"name":40,"class":41},{"id":468,"slug":469,"hasResults":11,"nctId":470,"briefTitle":471,"officialTitle":472,"acronym":473,"eligibilityCriteria":474,"healthyVolunteers":11,"sex":50,"minAge":18,"maxAge":168,"enrollmentInfo":475,"targetDuration":4,"studyType":22,"phases":477,"briefSummary":478,"conditions":479,"keywords":480,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":484,"lastUpdatePostDateStruct":485,"startDateStruct":487,"completionDateStruct":489,"leadSponsor":491,"locationsCount":42},"100600168","comparing-two-therapies-to-improve-arm-function-after-stroke-100600168","NCT07093983","Comparing Two Therapies to Improve Arm Function After Stroke","Coupling Rehabilitation Versus Constraint Induced Movement Therapy in Post Stroke Patients With Upper Limb Impairment","CR vs CIMT","Inclusion Criteria: •Age 40-65 years old\n\n* Patients suffering from Sub acute stroke\n* Motor function score at Fugl-Meyer Assessment between 40-60\n* Fine motor assessment at Box and Block Test\\\u003C20\n* ADL's assessment at Motor Activity Log:\n\nAmount of use scale\\\u003C2.5 Quality of movement scale\\\u003C3\n\n\\-\n\nExclusion Criteria:\n\n* Individuals suffering from unstable angina, symptomatic heart failure, or uncontrolled hypertension\n* Physician determined unstable cardiovascular conditions\n* The patient has been diagnosed as having organ failure, including the heart, kidneys, and lungs\n* Patients with any traumatic musculoskeletal injury to upper limbs\n* Individuals who are experiencing cognitive impairment as a result of neurological conditions other than stroke.",{"count":476,"type":21},80,[24],"This clinical trial aims to compare the effects of coupling rehabilitation and constraint-induced movement therapy (CIMT) on improving arm function, hand skills, and daily activity performance in people who have upper limb weakness after a stroke. Participants will be randomly assigned to one of two groups and receive 12 weeks of therapy, including either CIMT or coupling rehabilitation along with conventional physical therapy. The study will evaluate which method is more effective in restoring movement and independence by using standardized assessments before, during, and after the intervention. The findings may help guide future rehabilitation approaches for stroke survivors",[331],[481,482,331,483],"CouplingRehabilitation","CIMT","impairment","2025-07-30",{"date":486,"type":35},"2025-08-03",{"date":488,"type":21},"2025-08-05",{"date":490,"type":21},"2026-05-01",{"name":40,"class":41},{"id":493,"slug":494,"hasResults":11,"nctId":495,"briefTitle":496,"officialTitle":496,"acronym":4,"eligibilityCriteria":497,"healthyVolunteers":11,"sex":50,"minAge":498,"maxAge":51,"enrollmentInfo":499,"targetDuration":4,"studyType":22,"phases":500,"briefSummary":501,"conditions":502,"keywords":505,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":515,"lastUpdatePostDateStruct":516,"startDateStruct":518,"completionDateStruct":519,"leadSponsor":520,"locationsCount":42},"100597528","synergic-effects-of-schroth-method-with-and-without-core-stabilization-exercises-in-idiopathic-scoliosis-patients-100597528","NCT07059663","Synergic Effects of Schroth Method With and Without Core Stabilization Exercises in Idiopathic Scoliosis Patients","Inclusion Criteria:\n\n* • Age 10 to 18\n\n  * X-ray diagnosed of idiopathic scoliosis with Cobb Angle 10˚- 30˚\n  * Participants with Idiopathic Scoliosis\n  * Both genders will be included\n  * Scoliosis with Down syndrome.\n\nExclusion Criteria:\n\n* Any neurological condition such as cerebral palsy or epilepsy.\n* Any other orthopedic condition such as hip dysplasia, osteogenesis imperfecta, or leg length discrepancy.\n* Surgical history of the spine, such as spinal fusion and decompression surgery.\n* Severe systemic disorders such as autoimmune disorders, severe cardiovascular conditions\n* Non-Idiopathic Scoliosis","10 Years",{"count":85,"type":21},[24],"A randomized controlled trial was conducted on 72 patients diagnosed with idiopathic scoliosis at the University of Lahore Teaching Hospital. The study aimed to explore the synergistic effects of the Schroth method with and without core stabilization exercises. Participants were randomly allocated into two groups: Group A, which received both the Schroth method and core stabilization exercises, and Group B, which received only the Schroth method. The intervention lasted for 10 weeks, with assessments conducted at baseline, the 5th week, and the 10th week. Outcome measures included Cobb angle (spinal curvature), lumbar extensor endurance (Sorensen test), chest mobility, and quality of life (SRS-22 questionnaire). The study found significant improvements in all outcome measures for both groups, with Group A showing superior results. The addition of core stabilization exercises to the Schroth method resulted in better reductions in Cobb angle, enhanced lumbar extensor endurance, and improved chest mobility and quality of life, indicating a synergistic effect of the combined approach. The findings suggest that incorporating core stabilization exercises into scoliosis treatment protocols can lead to superior clinical outcomes.",[503,504],"Scoliosis","Scoliosis Idiopathic",[506,507,508,509,510,511,512,513,514,65],"Schroth Method","Idiopathic Scoliois","Core Stabilization Exercises","Cobb Angle","Lumbar Extensor Endurance","Chest mobility","SRS-22 questionnaire","Postural correction","Spinal deformity","2025-07-10",{"date":517,"type":35},"2025-07-15",{"date":484,"type":21},{"date":278,"type":21},{"name":40,"class":41},{"id":522,"slug":523,"hasResults":11,"nctId":524,"briefTitle":525,"officialTitle":525,"acronym":4,"eligibilityCriteria":526,"healthyVolunteers":11,"sex":50,"minAge":83,"maxAge":527,"enrollmentInfo":528,"targetDuration":4,"studyType":22,"phases":529,"briefSummary":530,"conditions":531,"keywords":533,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":539,"lastUpdatePostDateStruct":540,"startDateStruct":542,"completionDateStruct":544,"leadSponsor":546,"locationsCount":42},"100596621","bowen-technique-versus-dynamic-soft-tissue-mobilization-on-pain-range-of-motion-and-functional-disability-in-patients-with-adhesive-capsulitis-100596621","NCT07047846","Bowen Technique Versus Dynamic Soft Tissue Mobilization on Pain, Range of Motion and Functional Disability in Patients With Adhesive Capsulitis","Inclusion Criteria:\n\n* Diagnosed patients of 50-80 years of age\n* Grade 2 \\& 3 (frozen and thawing) adhesive capsulitis\n* patients willing to participate in the study\n* Only diabetic patients\n\nExclusion Criteria:\n\n* Major mental health probleme\n* Patients who has a history of surgery on the shoulder, other shoulder diseases including a rotator cuff tear, sub acromial impingement syndrome, and a shoulder labral tear\n* Patients taking oral or intra-articular steroids and cortisone injection prior 3 months\n* Subjects with rotator cuff tears or other shoulder ligament injuries, H\u002FO arthritis related to shoulder, malignancy, adhesive capsulitis secondary to fractures, dislocation, reflex sympathetic dystrophy, neurological disorder","80 Years",{"count":85,"type":21},[24],"A randomized controlled trial included 72 patients diagnosed with adhesive capsulitis will conduct in University of Lahore Teaching Hospital. The study will complete within 9 months after the approval of synopsis. Patients who fulfilled the inclusion criteria will identified by individual physiotherapist and will enrolled for particular study. Informed written consent will be taken by the patients and will randomly allocated into two groups. The total numbers of sessions will 12 (3 sessions per week). The study will single blinded. The assessor will unaware of the treatment given to both groups.\n\nControl group received routine physical therapy with dynamic soft tissue mobilization technique.\n\nthermotherapy, trans-cutaneous electrical nerve stimulation, shoulder isometrics and stretching that includes 12 sessions and three times per week. Experimental group received routine physical therapy along with Bowen technique. This includes thermotherapy, trans-cutaneous electrical nerve stimulation, shoulder isometrics and stretching that includes 12 sessions and three times per week",[532],"Adhesive Capsulitis",[532,534,535,536,537,538],"Bowen Therapy","Dynamic Soft Tissue Mobilization","range of motion","Shoulder Pain","physiotherapy","2025-07-01",{"date":541,"type":35},"2025-07-02",{"date":543,"type":21},"2025-07-16",{"date":545,"type":21},"2026-01-03",{"name":40,"class":41},""]