[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Latvia\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":108},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,81],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100537236","h-pylori-screen-and-treat-study-in-a-population-of-young-adults-100537236",false,"NCT06275204","H. Pylori Screen-and-treat Study in a Population of Young Adults","Multicentric Transnational H. Pylori Screen-and-treat Study in a Population of Young Adults","Inclusion Criteria:\n\n* Young adults (generally 30 - 34 years of age)\n\nExclusion Criteria:\n\n* Patients with mental or developmental limitations who cannot provide a fully-informed consent to participate (based on the assessment from research or patient's personal physician team)\n* Previously treated H. pylori infection\n* History of partial or total gastric resection due to benign or malign lesions",true,"ALL","30 Years","34 Years",{"count":21,"type":22},6800,"ESTIMATED","OBSERVATIONAL","Gastric cancer remains a major challenge to public health on a global scale. H. pylori related cancer burden contributes to the largest proportion of cancer cases attributable to infections in Europe. Considering its absolute burden and persisting disparities, in addition to the substantial prevalence of H. pylori infection worldwide that is treatable, gastric cancer is a logical target for urgent action for prevention. Population-based H. pylori test-and-treat has therefore been proposed as a strategy for gastric cancer prevention. To fill the gaps in knowledge about gastric cancer prevention through H. pylori screening and eradication in younger adults, a study of a population-based H. pylori test-and-treat strategy in Ireland, Croatia, Latvia, Poland, Romania and Slovenia.\n\nMain goals of this study are to assess future program processes, feasibility, acceptability and effectiveness. In total of 6,800 adults aged 30-34 will be tested for H. pylori infection. They will be randomly selected to represent the chosen population and invited to participate in the study based on informed consent. Confirmed infections will be treated by available combined therapy in line with treatment guidelines and the success of eradication will be retested during a control check-up.\n\nPatients who will provide their consent to participate will undertake an interview about the risk factors in early childhood and their habits regarding alcohol consumption and use of tobacco. Compliance to testing and treatment, treatment results, adverse effects and reasons for dropping out will be additionally monitored. Gathered data will be analysed in alignment with our research questions. The investigators will disseminate reports and present the results to both the general public and the scientific community in order to foster future developments in gastric cancer prevention.",[26,27,28,29],"Gastric Cancer","H Pylori Infection","H Pylori Eradication","H-pylori",[31,32,33,34],"H. pylori","gastric cancer","eradication therapy","screening","RECRUITING","2024-03-03",{"date":38,"type":39},"2024-03-05","ACTUAL",{"date":41,"type":22},"2024-03-04",{"date":43,"type":22},"2026-12-01",{"name":45,"class":46},"University of Latvia","OTHER",7,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},"100364198","screening-of-gastric-cancer-via-breath-volatile-organic-compounds-by-hybrid-sensing-approach-100364198","NCT04022109","Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach","VOGAS","Inclusion Criteria:\n\n* Patients with verified gastric cancer (Group 1 \\& 2)\n* Patients undergoing or having undergone upper endoscopy according to clinical indications (Group 3 \\& 5)\n* Average-risk population group aged 40-64 at inclusion without alarm symptoms (Group 4)\n* Motivation to participate in the study\n* Physical status allowing volatile marker sampling and other procedures within the protocol\n* Signed consent\n\nExclusion Criteria:\n\n* Known other active cancer\n* Ventilation problems, airway obstruction\n* Unwillingness or inability to co-operate","18 Years",{"count":57,"type":22},5000,"The study is aimed to determine the potential of volatile marker testing for gastric cancer screening.\n\nThe study will be addressing the role of confounding factors, including lifestyle factors, diet, smoking as well as addressing the potential role of microbiota in the composition of exhaled volatile markers.",[26,60,61,62],"Atrophic Gastritis","Gastric Dysplasia","H.Pylori Infection",[64,65,66,67,68,69,70,71],"Volatile organic compounds","Breath testing","Gastric cancer","Atrophic gastritis","Precancerous lesions","Screening","Nanosensor technology","GC-MS","2021-07-19",{"date":74,"type":39},"2021-07-26",{"date":76,"type":39},"2019-11-01",{"date":78,"type":22},"2026-12",{"name":45,"class":46},5,{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":16,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},"100304969","surveillance-of-patients-with-precancerous-lesions-of-the-stomach-100304969","NCT03250091","Surveillance of Patients With Precancerous Lesions of the Stomach","Surveillance Strategies of Patients With Precancerous Conditions and Lesions in the Stomach","Inclusion Criteria:\n\nPatients undergoing upper endoscopy Motivation to participate in the study Signed consent\n\nExclusion Criteria:\n\nKnown gastric cancer Unwillingness or inability to co-operate",{"count":89,"type":22},2000,"The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals. Implementing risk stratification only high risk individuals will be offered and performed endoscopic surveillance.",[26,92,93,61],"Gastric Intestinal Metaplasia","Gastric Atrophy",[95,32,96,97,98],"gastric precancerous lesions","gastric intestinal Metaplasia","gastric atrophy","gastric dysplasia","2018-08-20",{"date":101,"type":39},"2018-08-21",{"date":103,"type":39},"2017-06-19",{"date":105,"type":22},"2027-12",{"name":45,"class":46},1,""]