[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Maia\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":296},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,50,80,108,135,156,180,203,226,251,274],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100621347","community-based-power-training-in-faller-and-non-faller-older-adults-a-feasibility-and-fall-risk-study-100621347",false,"NCT07369440","COMMUNITY-BASED POWER TRAINING IN FALLER AND NON-FALLER OLDER ADULTS: A FEASIBILITY AND FALL RISK STUDY.","Community-based Power Training in Faller and Non-faller Older Adults: a Feasibility and Fall Risk Study.","POWER-AEQ","Inclusion Criteria:\n\n* Age between 65-85 years;\n* Fall history over the 12 months prior to enrollment (fallers group).\n\nExclusion Criteria:\n\n* Any existing medical conditions or injuries which would affect the ability or safety to perform exercise;\n* Taking medication affecting balance (such as sedatives, anti-depressives);\n* Regular (more than 1d\u002Fweek) participation in resistance training with loading greater than bodyweight during the last year;\n* BMI greater than 32 kg\u002Fm2.","ALL","65 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","Aging leads to substantial alterations in the nervous and skeletal muscle systems that ultimately lead to a reduction in \"neural drive\" and motor performance. While maximal strength starts declining as early as 50 years of age, aging brings even greater reductions in rate of force development and muscle power, that has been shown to be a stronger predictor of functional independence and balance impairments.\n\nFalls are a major health concern as one third of adults over 65 years loses balance and falls every year, and based on a published report, the estimated health care costs associated with falls in the European Union is €25 billion.\n\nThe ability to recover balance declines with aging, where older individuals often recover balance with a greater number of balance recovery steps and non-optimal stepping strategies. In addition, older adults have more difficulty recovering balance in the medio-lateral direction. The hip abductors are fundamental in controlling the motion of the body centre of mass in this direction during weight transfers of standing, stepping, and walking.\n\nFurthermore, these muscles appear to be more susceptible to age-related composition and performance declines than other muscles of the lower limbs, especially in individuals at a higher risk for falls.\n\nUnfortunately, common balance interventions, such as, functional balance training, Tai-Chi, or dance, have a very limited capacity to reduce the risk of falls in older adults. Interestingly, resistance training is relatively better than the mentioned interventions at reducing this problem. This may come about through mitigating the agerelated neuromuscular performance deficits. However, traditional resistance training lacks the emphasis in high velocity movements required for adequate fall prevention protective stepping strategies. Muscle power training is a safe and effective alternative to traditional resistance training. By emphasizing in maximum speed of execution, its results are often better than with traditional resistance training, especially in functional outcomes, with the potential to enhance balance recovery. However, there is little and inconsistent evidence on the optimal exercise parameters (such as velocity) for prevention of falls.\n\nCommunity-based multi-component exercise programs are often used to promote health and functional benefits in the older adult population. These programs not only have a positive impact in a larger number of communitydwelling individuals, but can also lead to significant improvements. Nonetheless, these programs limited in reducing the risk for falls. Considering the robust effects of muscle power training in the older population, it is conceivable that a multi-component community-based exercise intervention, that focuses on developing muscle power and reduce fall risk, can improve the older individuals' ability to recover balance and consequently, bring greater benefits to the older adult community. However, there is no information on the feasibility of conducting an exercise program to develop muscle power and reduce fall risk in a community-based setting. Furthermore, it is generally unknown if such an exercise intervention can improve function, balance, and reduce the occurrence of falls in older adults especially, among those that have fallen in the past- which are the most relevant target population for both clinical studies and practice.",[27,28,29,30],"Fall Prevention","Muscle Power Performance","Functional Mobility","Balance Control in Elderly",[32,33,34,35,36],"Older adults","Fallers","Power Training","Functional mobility","Balance","RECRUITING","2026-01-18",{"date":40,"type":41},"2026-01-27","ACTUAL",{"date":43,"type":41},"2024-09-01",{"date":45,"type":21},"2027-08-30",{"name":47,"class":48},"University of Maia","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":17,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100619353","effects-of-sulforaphane-supplementation-on-athletic-performance-100619353","NCT07343518","Effects of Sulforaphane Supplementation on Athletic Performance","Effects of Sulforaphane Supplementation on Athletic Performance: a Double-blinded Randomized Crossover Study","Inclusion Criteria:\n\n* Physically active individuals (engaging in exercise 3 or more times per week)\n\nExclusion Criteria:\n\n* Individuals that experience musculoskeletal injuries or have experienced in the past 3 months",true,"18 Years","35 Years",{"count":61,"type":21},20,[24],"Considering the promising effects observed and the scarce and incipient scientific background of SFN in sports, the present study aims to evaluate the effects of SFN supplementation on fatigue, EIMD and recovery in trained individuals. In particular, outcomes such as time to exhaustion (TTE), and perceptual questionnaires of muscle soreness, recovery, and fatigue will be assessed, aiming to explore the effectiveness of SFN.",[65,66],"Nutrition","Sports",[68,69,70],"sulforaphane","fatigue","athletic performance","NOT_YET_RECRUITING","2026-01-06",{"date":74,"type":41},"2026-01-15",{"date":76,"type":21},"2026-01-02",{"date":78,"type":21},"2026-05-01",{"name":47,"class":48},{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":57,"sex":87,"minAge":58,"maxAge":59,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":90,"briefSummary":91,"conditions":92,"keywords":95,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":4},"100603385","ashwagandha-withania-somnifera-and-its-effects-on-recovery-perceived-and-muscle-strength-in-male-handball-players-100603385","NCT07135830","Ashwagandha (Withania Somnifera) and Its Effects on Recovery Perceived and Muscle Strength in Male Handball Players","Ashwagandha (Withania Somnifera) and Its Effects on Recovery Perceived and Muscle Strength in Male Handball Players: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Handball players competing nationally\n\nExclusion Criteria:\n\n* Injured athletes\n* Female athletes","FEMALE",{"count":89,"type":21},30,[24],"This study aims to assess the potential recovery and strength effects of male handball players.",[93,94],"Strength Training Adaptations","Recovery",[96,97,98,99],"ashwagandha","strength","recovery","handball","2025-08-15",{"date":102,"type":41},"2025-08-22",{"date":104,"type":21},"2025-08-25",{"date":106,"type":21},"2025-09-30",{"name":47,"class":48},{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":115,"targetDuration":4,"studyType":22,"phases":117,"briefSummary":118,"conditions":119,"keywords":121,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":49},"100595535","exercise-in-hereditary-attr-attrv-amyloidosis-100595535","NCT07033715","Exercise in Hereditary ATTR (ATTRv) Amyloidosis","Effects of a 12-week Exercise Intervention on Physical and Mental Health in Hereditary ATTR (ATTRv) Amyloidosis","Inclusion Criteria:\n\n* ATTRv Amyloidosis patients living in Portugal;\n* Disease stage 1 or 2;\n* No medical contraindication for exercising;\n* Ability to provide informed consent.\n\nExclusion Criteria:\n\n\\- Having undergone a liver transplant in the past 6 months.",{"count":116,"type":21},42,[24],"This study aims to explore the effects of a 12-week exercise intervention on the physical and mental health of people living with Hereditary ATTR (ATTRv) Amyloidosis, a rare genetic disease caused by mutations in the transthyretin gene, leading to the deposition of amyloid fibrils in nerves and organs.",[120],"Amyloidosis, Hereditary, Transthyretin-Related",[122,123,124,125,126],"ATTRv","exercise","physical fitness","mental health","HRQoL","2025-06-22",{"date":129,"type":41},"2025-06-24",{"date":131,"type":41},"2024-10-01",{"date":133,"type":21},"2026-09-30",{"name":47,"class":48},{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":4,"eligibilityCriteria":141,"healthyVolunteers":57,"sex":142,"minAge":58,"maxAge":59,"enrollmentInfo":143,"targetDuration":4,"studyType":22,"phases":144,"briefSummary":145,"conditions":146,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":4},"100586258","myocene-sensivity-to-cycling-intensities-100586258","NCT06913036","Myocene Sensivity to Cycling Intensities","Muscular Response to Short vs. Prolonged Cycling: A Crossover Trial on Low-Frequency Fatigue Sensitivity","Inclusion Criteria:\n\n* Road cyclists\n\nExclusion Criteria:\n\n* Injured or recently injured participants","MALE",{"count":61,"type":21},[24],"This study aims to address this gap by assessing LFF following different efforts in cycling, aiming to identify a pattern. Also, we expect that this study helps to clarify to which efforts (prolonged vs short) are more likely to trigger substantial changes in LFF responses.",[147],"Fatigue Intensity","2025-04-02",{"date":150,"type":41},"2025-04-06",{"date":152,"type":21},"2025-04",{"date":154,"type":21},"2025-07",{"name":47,"class":48},{"id":157,"slug":158,"hasResults":11,"nctId":159,"briefTitle":160,"officialTitle":161,"acronym":4,"eligibilityCriteria":162,"healthyVolunteers":57,"sex":142,"minAge":163,"maxAge":164,"enrollmentInfo":165,"targetDuration":4,"studyType":22,"phases":167,"briefSummary":168,"conditions":169,"keywords":171,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":177,"leadSponsor":179,"locationsCount":4},"100586870","can-lower-body-occlusion-influence-sports-recovery-100586870","NCT06921005","Can Lower-body Occlusion Influence Sports Recovery?","Can Lower-body Occlusion During Low-intersity Cycling Influence Recovery of Youth Elite Soccer Players?","Inclusion Criteria:\n\n* soccer players\n* elite athletes\n* present in the pitch training sessions\n\nExclusion Criteria:\n\n* injured athletes\n* female athletes","17 Years","23 Years",{"count":166,"type":21},15,[24],"This study ai ms to compare the recovery kinetics of different interventions: i) active recovery; ii) continuous vascular occlusion during active recovery; iii) intermittent vascular occlusion during active recovery; iv) control group.",[170,66],"Recovery of Function",[172,98,173],"sports","blood flow restriction",{"date":175,"type":41},"2025-04-10",{"date":175,"type":21},{"date":178,"type":21},"2025-06-20",{"name":47,"class":48},{"id":181,"slug":182,"hasResults":11,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":4,"eligibilityCriteria":186,"healthyVolunteers":57,"sex":17,"minAge":58,"maxAge":187,"enrollmentInfo":188,"targetDuration":4,"studyType":190,"phases":4,"briefSummary":191,"conditions":192,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":198,"completionDateStruct":200,"leadSponsor":202,"locationsCount":4},"100579911","test-retest-reliability-of-myocene-100579911","NCT06830447","Test-retest Reliability of Myocene","Test-retest Reliability of Low-frequency Fatigue Assessed Using Myocene","Inclusion Criteria:\n\n* active individuals\n\nExclusion Criteria:\n\n* injured participants\n* unhealthy volunteers","40 Years",{"count":189,"type":21},50,"OBSERVATIONAL","The test retest reliability of Myocene will be tested.",[193,194],"Reliability","Fatigue","2025-02-11",{"date":197,"type":41},"2025-02-17",{"date":199,"type":21},"2025-03",{"date":201,"type":21},"2025-05",{"name":47,"class":48},{"id":204,"slug":205,"hasResults":11,"nctId":206,"briefTitle":207,"officialTitle":208,"acronym":4,"eligibilityCriteria":209,"healthyVolunteers":57,"sex":142,"minAge":210,"maxAge":211,"enrollmentInfo":212,"targetDuration":4,"studyType":190,"phases":4,"briefSummary":213,"conditions":214,"keywords":215,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":221,"completionDateStruct":223,"leadSponsor":225,"locationsCount":4},"100570254","influence-of-acute-daily-workload-changes-on-low-frequency-fatigue-morning-scores-100570254","NCT06704854","Influence of Acute Daily Workload Changes on Low-frequency Fatigue Morning Scores","Influence of Acute Daily Workload Changes on Low-frequency Fatigue Morning Scores Throughout an In-season Soccer Microcycle","Inclusion Criteria:\n\n* elite soccer players\n\nExclusion Criteria:\n\n* injured athletes","16 Years","21 Years",{"count":61,"type":21},"In recent years, the increased demands of both training and competition have heightened the need of load monitoring among soccer players. However, adopting metrics that comprehensively capture the intricacies of neuromuscular fatigue remains a challenge. Assessing low-frequency fatigue may contribute to fill this gap, as it provides an objective measure to evaluate muscle function readiness. Thus, the aim of this study was to examine whether variability in low-frequency fatigue morning scores are related to training external load acute changes throughout the in-season microcycle.",[147],[69,216,217],"low-frequency fatigue","soccer","2024-11-21",{"date":220,"type":41},"2024-11-26",{"date":222,"type":21},"2024-11-25",{"date":224,"type":21},"2025-01-15",{"name":47,"class":48},{"id":227,"slug":228,"hasResults":11,"nctId":229,"briefTitle":230,"officialTitle":231,"acronym":4,"eligibilityCriteria":232,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":233,"targetDuration":4,"studyType":22,"phases":235,"briefSummary":236,"conditions":237,"keywords":241,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":248,"leadSponsor":250,"locationsCount":49},"100568302","emotion-aging-and-forgiveness-protocol-for-a-feasibility-of-randomized-controlled-trial-100568302","NCT06679452","Emotion, Aging, and Forgiveness: Protocol for a Feasibility of Randomized Controlled Trial","Emotion, Aging and Forgiveness: Protocol of a Feasibility and Acceptability Study of Emotion-Focused Therapy for Older Individuals","Inclusion Criteria:\n\n* Our eligibility criteria include being 65 years or older, having experienced an interpersonal offense, residing at home or in a senior residence, stable prescribed medication use, scoring ≥ 26 on the MoCA (Montreal Cognitive Assessment), and fluency in Portuguese or English.\n\nExclusion Criteria:\n\n* Exclusion criteria include reporting an offense which is less than a year old, severe emotional injuries (such as being a victim of domestic violence or abuse), psychiatric disorders, suicidal ideation, parasuicidal behavior, recent loss of a loved one, involvement in other therapies or clinical studies, current alcohol or drug abuse, living with another participant, and frequent hospitalizations.",{"count":234,"type":21},70,[24],"Over recent decades, Emotion-Focused Therapy, aging, and forgiveness have garnered significant attention in the field of psychology. However, there is a lack of studies on Emotion-Focused Therapy and forgiveness specifically tailored for older adults. This article describes a protocol to assess the feasibility and acceptability of a Randomized Controlled Trial of Emotion-Focused Therapy for the resolution of emotional injury in individuals over the age of 65 in the context of interpersonal offenses. The study is structured as a two-arm, parallel-group randomized trial with a waiting list control. We propose recruiting a sample of 70 participants, randomly assigned to either an immediate intervention group, which will receive Emotion-Focused Therapy over twelve weekly sessions, or a control group that will receive the same therapy after a twelve-week waiting period. Data will be collected in the beginning, middle, and at the end of therapy, and in two planned follow-ups (three and six months after therapy). Once this protocol is implemented, if the therapy proves to be feasible, acceptable, and shows promising results, the findings will inform a large-scale randomized clinical trial to advance the understanding of psychotherapy.",[238,239,240],"Emotion-Focused Therapy","Aging","Forgiveness",[242],"Emotion-Focused Therapy; Forgiveness; Aging; Randomized Controlled Trial; Feasibility Protocol","2024-11-10",{"date":245,"type":41},"2024-11-13",{"date":247,"type":21},"2025-04-01",{"date":249,"type":21},"2025-12-31",{"name":47,"class":48},{"id":252,"slug":253,"hasResults":11,"nctId":254,"briefTitle":255,"officialTitle":256,"acronym":4,"eligibilityCriteria":257,"healthyVolunteers":57,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":258,"targetDuration":4,"studyType":22,"phases":260,"briefSummary":261,"conditions":262,"keywords":264,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":267,"lastUpdatePostDateStruct":268,"startDateStruct":270,"completionDateStruct":272,"leadSponsor":273,"locationsCount":4},"100565033","time-at-vo2max-during-high-intensity-interval-training-100565033","NCT06636916","Time at VO2max During High-Intensity Interval Training","Time at VO2max During High-Intensity Interval Training Manipulating Work and Rest","Inclusion Criteria:\n\n* Middle and long distance track and field athletes\n\nExclusion Criteria:\n\n* Injured athletes",{"count":259,"type":21},10,[24],"The project titled \"Time at VO2max During High-Intensity Interval Training Manipulating Work and Rest\" aims to investigate how different high-intensity interval training (HIIT) protocols influence the time athletes spend at or above 90% of their VO2max. By adjusting the work-to-rest ratios in the HIIT formats, the study seeks to determine which configurations maximize the time spent in this high-intensity zone, contributing to more effective endurance training strategies. The findings could help optimize training protocols for athletes targeting improvements in aerobic capacity and performance.",[263],"High Intensity Interval Exercise (HIIE)",[172,265,70,266],"hiit","vo2max","2024-10-10",{"date":269,"type":41},"2024-10-15",{"date":271,"type":21},"2024-11",{"date":199,"type":21},{"name":47,"class":48},{"id":275,"slug":276,"hasResults":11,"nctId":277,"briefTitle":278,"officialTitle":279,"acronym":4,"eligibilityCriteria":280,"healthyVolunteers":57,"sex":142,"minAge":210,"maxAge":211,"enrollmentInfo":281,"targetDuration":4,"studyType":190,"phases":4,"briefSummary":283,"conditions":284,"keywords":286,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":49},"100551290","associations-between-low-frequency-fatigue-jump-height-and-perceptual-measures-of-muscle-soreness-fatigue-and-recovery-100551290","NCT06458166","Associations Between Low Frequency Fatigue, Jump Height and Perceptual Measures of Muscle Soreness, Fatigue and Recovery","Associations Between Low Frequency Fatigue, Jump Height and Perceptual Measures of Muscle Soreness, Fatigue and Recovery in Youth Elite Soccer Players","Inclusion Criteria:\n\n* Elite level youth soccer players, competing in the highest portuguese division\n\nExclusion Criteria:\n\n* Older adults\n* none elite soccer player\n* Play less than 70 minutes of match",{"count":282,"type":21},40,"Over the recent years, the increased competitive demands in elite competitive athletes has sparked a heightened interest in monitoring fatigue. Given the nature of the soccer game, athletes may experience low-frequency fatigue. Until recently, this assessment was restricted to in-lab. However, the emergence of new instruments aiming to allow low-frequency assessment to be carried out on a daily basis, in the context of professional teams. This study aimed to analyze the recovery of low-frequency fatigue, jump height and perceptual responses following competition and investigate possible associations between the objective and subjective parameters.",[194,285],"Physical Exercise",[172,217,287],"low frequency fatigue","2024-06-07",{"date":290,"type":41},"2024-06-13",{"date":292,"type":21},"2024-07-01",{"date":294,"type":21},"2024-09-30",{"name":47,"class":48},""]