[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Malaga\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":564},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,21,0,[8,47,83,111,141,173,214,242,263,287,307,335,366,389,405,423,440,462,488,509,532],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100643887","thumb-muscle-activation-during-first-dorsal-interosseous-activities-of-daily-living-in-thumb-base-osteoarthritis-100643887",false,"NCT07668986","Thumb Muscle Activation During First Dorsal Interosseous Activities of Daily Living in Thumb Base Osteoarthritis","A Between-Group Comparison of First Dorsal Interosseous and Abductor Pollicis Longus Muscle Activation During First Dorsal Interosseous Activities of Daily Living in Individuals With and Without Thumb Base Osteoarthritis","Inclusion criteria for the TMC OA group:\n\n\\- Clinical diagnosis of thumb TMC osteoarthritis.\n\nInclusion criteria for the healthy group:\n\n\\- Participants with no history of musculoskeletal or neurological disorders affecting the dominant hand were included.\n\nExclusion Criteria :\n\n* Presence of numbness, tingling, or other sensory disturbances\n* Cardiac pacemaker implantation\n* Upper limb entrapment neuropathy or cervical radiculopathy\n* History of neuromuscular disease, polyneuropathy, or plexopathy\n* Systemic diseases such as diabetes, hypothyroidism, or chronic liver or kidney disease\n* History of cancer, rheumatoid arthritis, active anticoagulation therapy, chemotherapy, or exposure to neurotoxins\n* Recent upper limb soft tissue or bone injury (trauma, fracture, or surgery of the arm or neck).",true,"ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","4 Months","OBSERVATIONAL","The aim of this study is to investigate whether there are differences in muscle activation of the First Dorsal Interosseous (FDI) and the Abductor Pollicis Longus (APL) between individuals with and without trapeziometacarpal osteoarthritis (TMC OA) of the thumb during the performance of six activities of daily living (ADLs).\n\nThe FDI has been defined as a key stabilizer of the TMC joint of the thumb. However, the literature reports limited information on FDI and APL activation during ADLs. TMC OA of the thumb can cause pain, decreased thumb strength, impaired hand function, and difficulty performing ADLs. Understanding muscle activation patterns during these activities is essential to comprehend how this condition affects hand function and to guide more specific and effective rehabilitation strategies.\n\nParticipants will perform six ADLs: turning a key to open, turning a key to close, picking up a coin, writing, squeezing a tube of toothpaste, and holding a glass of water. Muscle activity will be recorded using surface electromyography (sEMG) during all tasks.\n\nAdults aged 30 years and older, both men and women, with TMC osteoarthritis and healthy controls without osteoarthritis will be invited to participate.\n\nResearchers will measure the activation patterns of the FDI and APL muscles during the ADLs, with the aim of identifying differences between both groups and providing evidence to guide the rehabilitation of patients with thumb base osteoarthritis.",[26],"Trapeziometacarpal Osteoarthritis",[28,29,30,31,32,33],"muscle activation","Trapeziometacarpal osteoarthritis","first dorsal interosseous","abductor pollicis longus","surface electromyography","activities daily living","NOT_YET_RECRUITING","2026-06-21",{"date":37,"type":38},"2026-06-25","ACTUAL",{"date":40,"type":21},"2026-06-05",{"date":42,"type":21},"2026-08-30",{"name":44,"class":45},"University of Malaga","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":46},"100644141","effects-of-virtual-assistant-features-on-user-experience-in-service-settings-100644141","NCT07666295","Effects of Virtual Assistant Features on User Experience in Service Settings","Virtual Assistants as Agents of Change: Improving User Interaction and User Experience Outcomes in Service Delivery","AVir4Services","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Able to understand the study information and provide informed consent.\n* Sufficient proficiency in Spanish to understand the instructions and complete the study questionnaires.\n* Able to interact with a computer-based virtual assistant and complete the experimental session.\n* Willing to complete the study procedures, which may include questionnaires, eye tracking, electrodermal activity recording, electroencephalography, and facial expression recording.\n\nExclusion Criteria:\n\n* Younger than 18 years.\n* Unable to understand the study information or provide valid informed consent.\n* Insufficient proficiency in Spanish to understand the instructions or complete the questionnaires.\n* A visual, hearing, motor, or other condition that prevents completion of the specific experimental task and cannot be accommodated by the study procedures.\n* A temporary health condition, discomfort, or technical incompatibility that, according to the study procedures, prevents safe or reliable completion of the experimental session.\n* Previous participation in the same experimental protocol, when prior exposure could influence the study outcomes.",{"count":56,"type":21},400,"INTERVENTIONAL",[59],"NA","This study examines how the characteristics and performance of virtual assistants influence user experience in service settings. Approximately 400 adults will interact with virtual assistants presented as avatars, chatbots, or voice assistants in simulated tourism, cultural, retail, or financial service situations.\n\nParticipants will be exposed to one or more experimental conditions that may differ in features such as communication style, language specificity, anthropomorphism, personalization, type of virtual assistant, level of immersion, or the presence of inaccurate responses or errors. After the interaction, participants will complete questionnaires about their perceptions, emotions, trust, satisfaction, acceptance of recommendations, and intention to use the virtual assistant.\n\nDuring the experimental session, non-invasive methods may be used to measure visual attention and psychophysiological responses. These methods include eye tracking, electrodermal activity, electroencephalography, and automated facial expression analysis. Facial recordings will be used to analyze emotional expressions and will not be used to identify participants.\n\nThe study does not involve drugs, biological products, medical treatments, diagnostic procedures, or investigational medical devices. Its purpose is to improve scientific understanding of human interaction with artificial intelligence and virtual assistants in service environments.",[62],"User Experience With Virtual Assistants in Service Settings",[64,65,66,67,68,69,70,71,72,73,74],"Virtual Assistants","Artificial Intelligence","Human-Computer Interaction","User Experience","Consumer Behavior","Technology Acceptance","Anthropomorphism","Eye Tracking","Electrodermal Activity","Electroencephalography","Facial Expression Analysis","2026-06-18",{"date":77,"type":38},"2026-06-24",{"date":79,"type":21},"2026-09",{"date":81,"type":21},"2028-01",{"name":44,"class":45},{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":57,"phases":94,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":46},"100642048","morphological-and-mechanical-assessment-in-the-achilles-tendon-after-radiofrequency-stimulation-in-runners-100642048","NCT07648199","Morphological and Mechanical Assessment in the Achilles Tendon After Radiofrequency Stimulation in Runners","Morphological and Mechanical Changes in the Achilles Tendon After the Application of INDIBA® Therapy in Healthy Runners: A Pre-post Quasi-experimental Study","RFAchillesRun","Inclusion Criteria:\n\n* Adults aged 18-65\n* Runners with at least one year of regular practice.\n* Must not have suffered any ligament, bone, tendon, or muscle injury in the lower limb or lumbar region during the last year.\n\nExclusion Criteria:\n\n* History of lower limb surgery, rheumatic or neuromuscular diseases or pregnancy\n* Contraindication for radiofrecuency treatment.\n* Athletes with visual, auditory, or any other impairment that may affect their cognitive ability to understand the test.","65 Years",{"count":93,"type":21},19,[59],"448 kHz capacitive-resistive monopolar radiofrequency is an emerging physiotherapy technique whose usefulness and clinical relevance still need to be investigated. This study is a pre-post quasi-experimental study in which several variables will be measured before and immediately after 448 kHz capacitive resistive monopolar radiofrequency. It aims to analyze the morphological and mechanical changes in the Achilles tendon following the intervention in healthy runners.",[97,98],"Achilles Tendon Injury","Achilles Tendon",[100,101,102],"Achilles tendon","Radiofrecuency","Physiotherapy","2026-06-14",{"date":105,"type":38},"2026-06-17",{"date":107,"type":21},"2026-07-01",{"date":109,"type":21},"2026-07-30",{"name":44,"class":45},{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":16,"sex":119,"minAge":120,"maxAge":18,"enrollmentInfo":121,"targetDuration":4,"studyType":57,"phases":123,"briefSummary":124,"conditions":125,"keywords":127,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":4},"100642625","preventive-exercise-program-for-adolescent-futsal-players-100642625","NCT07648186","Preventive Exercise Program for Adolescent Futsal Players.","Effect of a Preventive Exercise Progam on Lower-limb Injuries in Adolescent Futsal Players: a Randomized Controlled Trial.","INSPIRE","Inclusion Criteria:\n\n* Male futsal players.\n* Age between 15 and 18 years.\n* Players who have a confirmed team for all the season.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Cultural, ethical or language barrier.\n* Goalkeepers.\n* Participants with other diseases.","MALE","15 Years",{"count":122,"type":21},26,[59],"The main aim of this study is to analyse the effect of a preventive exercise program (INSPIRE: Indoor Sports Injury Prevention) on the lower-limb injuries in adolescent futsal players. For this purpose, 26 adolescent futsal players will be recruited, and after baseline evaluation, they will be randomized either the standard care, that will undergo the standard strengthening program developed each year in their team, or the experimental group, that will undergo the INSPIRE program, based on three stages (motor control, strength and endurance, and propioception and neural workout). Both groups will develop a 8-week intervention. Regarding the evaluation, the participants will have three evaluations: baseline, 4 weeks, and 8 weeks, and they will complete validated questionnaries (Overuse Injury Questionnaire, and Return to Play Score), together with functional tests (Y-Balance Test), strength testing using a dynamometer, and motor control testing using force plates.",[126],"Adolescent Futsal Players",[128,129,130,131,132],"Adolescent","Futsal","Lower-limb","Preventive","Exercise","2026-06-09",{"date":135,"type":38},"2026-06-15",{"date":137,"type":21},"2026-09-01",{"date":139,"type":21},"2027-06-15",{"name":44,"class":45},{"id":142,"slug":143,"hasResults":11,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":149,"enrollmentInfo":150,"targetDuration":4,"studyType":57,"phases":152,"briefSummary":153,"conditions":154,"keywords":159,"overallStatus":164,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":46},"100643195","virtual-reality-based-rehabilitation-for-traumatic-hand-and-wrist-injuries-100643195","NCT07633769","Virtual Reality-based Rehabilitation for Traumatic Hand and Wrist Injuries","Use of Virtual Reality to Improve Sensorimotor Function in Patients With Traumatic Wrist and Hand Injuries","AOT-VR-HAND","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Diagnosis of a traumatic wrist and\u002For hand injury.\n* Referred for rehabilitation treatment at the participating hand therapy unit.\n* Ability to understand study procedures and provide written informed consent.\n* Ability to participate in the virtual reality intervention.\n\nExclusion Criteria:\n\n* Previous injury affecting the same hand.\n* Associated upper-limb conditions, including tenosynovitis or Dupuytren's disease.\n* Previous surgery involving the affected hand before the current traumatic injury.\n* Corticosteroid or other therapeutic injection in the affected hand within the previous 3 weeks.\n* Any physical, neurological, visual, vestibular, or medical condition that prevents safe use of the virtual reality device.\n* Inability to comply with the study procedures or assessments.","75 Years",{"count":151,"type":21},40,[59],"This randomized controlled trial aims to evaluate the effectiveness of immersive virtual reality (VR)-based Action Observation Therapy (AOT) as an adjunct to conventional rehabilitation in patients with traumatic wrist and hand injuries. Participants will receive standard rehabilitation treatment, and the intervention group will additionally undergo a six-week VR program involving observation and execution of functional hand and wrist movements. Outcomes related to hand function, grip strength, pain, proprioception, disability, and psychological factors will be assessed to determine the potential benefits of incorporating VR into rehabilitation programs.",[155,156,157,158],"Wrist Injury","Hand and Upper Limb Trauma","Hand and Forearm Trauma","Muskuloskeletal Diseases",[160,161,162,163],"Virtual Reality","Upper limb rehabilitation","Sensorimotor Function","Functional recovery","RECRUITING","2026-06-02",{"date":167,"type":38},"2026-06-08",{"date":169,"type":38},"2026-02-01",{"date":171,"type":21},"2026-12-31",{"name":44,"class":45},{"id":174,"slug":175,"hasResults":11,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":179,"eligibilityCriteria":180,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":181,"targetDuration":4,"studyType":57,"phases":183,"briefSummary":184,"conditions":185,"keywords":195,"overallStatus":164,"whyStopped":4,"lastUpdateSubmitDate":205,"lastUpdatePostDateStruct":206,"startDateStruct":208,"completionDateStruct":210,"leadSponsor":212,"locationsCount":213},"100641032","effectiveness-of-best-care-practices-in-acute-stroke-in-conventional-hospitalization-best-care-ictushc-100641032","NCT07627399","Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC)","Effectiveness of Implementing Best Care Practices in the Management of Patients With Acute Stroke in Conventional Hospitalization: A Cluster-Randomized, Open, Stepped-Wedge Controlled Trial.","BESTCAREICTUS","Inclusion Criteria:\n\n* Patients aged 18 years or older.\n* Clinical diagnosis of acute ischemic or hemorrhagic stroke.\n* Admission to conventional hospitalization units (Internal Medicine) in regional hospitals without specialized Stroke Units.\n\nExclusion Criteria:\n\n* Patients admitted for a cause other than stroke who develop a stroke during their hospital stay (in-hospital stroke).\n* Patients subjected to invasive neurological procedures.\n* Patients undergoing invasive procedures, such as thrombectomy, who require transfer to a referral hospital and remain there for more than 48 hours.\n* Patients with deterioration of the level of consciousness that prevents the performance of dysphagia testing.\n* Patients that have been taken care of by Nurses and Nursing Assistants with \\>4 weeks of work experience in Stroke Units in the last 12 months",{"count":182,"type":21},700,[59],"The goal of this clinical trial is to evaluate whether a multicomponent nurse-led intervention (BEST CARE ICTUS\\_HC) can reduce stroke-related complications and improve recovery in adults (18 years and older) hospitalized with an acute ischemic or hemorrhagic stroke in hospitals without specialized Stroke Units. The main questions it aims to answer are:\n\n1. Does the implementation of the program increase the early and correct detection of swallowing difficulties (dysphagia) to prevent pneumonia?\n2. Does the program reduce the severity of attention problems (hemineglect) and improve the patients' quality of life up to 6 months after discharge?\n\nResearchers will compare patients receiving the BEST CARE ICTUS\\_HC program to patients receiving usual hospital care to see if this new approach improves patient safety and long-term functional recovery.\n\nParticipants will:\n\n* Receive either the usual hospital care for stroke or the BEST CARE ICTUS\\_HC nursing program, depending on the study phase of the hospital.\n* Be screened for swallowing problems using a standardized test before receiving any food or drink.\n* Be cared for in an adapted environment (FLECHA Project) that uses visual signs and room organization to help with orientation and safety.\n* Have their temperature, blood sugar, and blood pressure monitored under a strict specialized protocol.\n* Be contacted by phone 30 days and 6 months after leaving the hospital to answer questions about their health and quality of life.",[186,187,188,189,190,191,192,193,194],"Stroke","Acute Stroke","Ischemic Stroke","Hemorrhagic Stroke","Cerebrovascular Disorders","Deglutition Disorders","Perceptual Disorders","Unilateral Neglect","Pneumonia, Aspiration",[187,196,197,193,198,199,200,201,202,203,204],"Nursing Care","Dysphagia Screening","Multicomponent Intervention","Care Bundle","Stepped-Wedge Design","Deglutition","Quality of life","Hyperglycemia","Fever","2026-05-29",{"date":207,"type":38},"2026-06-04",{"date":209,"type":38},"2026-05-12",{"date":211,"type":21},"2028-12",{"name":44,"class":45},4,{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":220,"eligibilityCriteria":221,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":222,"enrollmentInfo":223,"targetDuration":4,"studyType":57,"phases":224,"briefSummary":225,"conditions":226,"keywords":229,"overallStatus":164,"whyStopped":4,"lastUpdateSubmitDate":234,"lastUpdatePostDateStruct":235,"startDateStruct":237,"completionDateStruct":239,"leadSponsor":241,"locationsCount":46},"100609299","precision-of-pacient-specific-instrumented-open-wedge-high-tibial-osteotomy-vs-conventional-technicque-100609299","NCT07212777","Precision of Pacient-specific Instrumented Open Wedge High Tibial Osteotomy vs Conventional Technicque","Precisión de la osteotomía Tibial Proximal Con Instrumental Paciente-específico vs técnica Convencional","AMBE_OR","Inclusion Criteria:\n\n* Informed consent: able to sign informed consent\n* Clinical: predominantly medial pain\u002Flimitation refractory ≥3-6 months\n* Mobility: flexion ≥90º and flexion contracture ≤10º Stability: varus\u002Fvalgus and pivot-shift ≤ grade 1.\n* Radiology:\n\n  * Medial gonarthrosis Ahlbäck I-III with preserved lateral compartment.\n  * Patellofemoral Iwano 0-2 without disabling patellofemoral pain.\n  * Varus alignment: HKA 4-10°.\n  * Predominantly tibial deformity (decreased MPTA; LDFA close to normal) according to planning.\n* Anatomy\u002Ftechnical feasibility: proximal tibial morphology suitable for medial opening osteotomy and PSI guide placement.\n\nExclusion criteria:\n\n* Comorbidity\u002Fclinical situations:\n\n  * Inflammatory arthritis (e.g., RA, spondyloarthropathies), unresolved previous joint infection or osteomyelitis.\n  * Severe peripheral vasculopathy (ABI \\\u003C0.7), advanced peripheral neuropathy or Charcot foot.\n  * Poorly controlled diabetes (HbA1c \\>8.5%), advanced renal\u002Fhepatic failure (eGFR \\\u003C30 ml\u002Fmin\u002F1.73 m²; Child-Pugh B\u002FC).\n  * Smoking \\>20 cigarettes\u002Fday without commitment to cessation; active IV drug use or uncontrolled alcoholism.\n  * BMI \\>35 kg\u002Fm².\n  * Disorder affecting gait (e.g., neurological disease).\n  * Inability to walk at a speed of at least 0.8m\u002Fs\n* Anatomy\u002Fradiology\n\n  * Multiplanar deformities not correctable with isolated medial opening tibial valgus osteotomy (e.g., dominant femoral deformity).\n  * Severe medial subchondral bone defect or extensive necrosis.\n  * Sequelae of proximal tibia fracture or previous ipsilateral HTO that prevent correction or guide use.\n* Treatments\u002Fmedication and logistics\n\n  * Anticoagulation\u002Fantiplatelet therapy that cannot be suspended or bridged.\n  * Systemic corticosteroids \\>10 mg\u002Fday or high-risk immunosuppressants without possibility of adjustment.\n  * Intra-articular infiltration (HA\u002FCS\u002FPRP) within the previous 60 days (respect defined wash-out).\n  * Pregnancy.\n  * Participation in another interfering trial.\n  * Inability to undergo CT (e.g., uncontrollable claustrophobia).\n  * Inability to complete ≥12 months of follow-up.","70 Years",{"count":20,"type":21},[59],"This study is a randomized clinical trial that will compare two surgical techniques for patients with knee osteoarthritis and varus deformity who are candidates for medial opening wedge high tibial osteotomy. The goal is to evaluate whether using patient-specific 3D-printed surgical guides improves the accuracy of the bone cut compared with the conventional technique performed with anatomical landmarks and fluoroscopy.\n\nA total of 50 adult patients will be randomly assigned to one of two groups: conventional osteotomy or osteotomy assisted by patient-specific instrumentation (PSI). The main outcome is the accuracy of the osteotomy cut, measured by comparing preoperative planning with the postoperative CT scan. Secondary outcomes include leg alignment, surgical time, radiation exposure, complications, and functional recovery assessed with validated questionnaires (KOOS, WOMAC, IKDC, EQ-5D) and gait analysis using depth cameras.\n\nPatients will be followed for up to 12 months after surgery to evaluate clinical and radiological outcomes.",[227,228],"Arthritis (Knee)","Varus Knee",[230,231,232,233],"patient-specific instrumentation","knee osteotomy","Prospective","Randomised Controlled Trial","2026-04-02",{"date":236,"type":38},"2026-04-03",{"date":238,"type":38},"2025-11-15",{"date":240,"type":21},"2028-10",{"name":44,"class":45},{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":4,"eligibilityCriteria":248,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":249,"enrollmentInfo":250,"targetDuration":4,"studyType":57,"phases":251,"briefSummary":252,"conditions":253,"keywords":4,"overallStatus":164,"whyStopped":4,"lastUpdateSubmitDate":234,"lastUpdatePostDateStruct":256,"startDateStruct":258,"completionDateStruct":260,"leadSponsor":262,"locationsCount":46},"100543536","efficacy-of-early-multimodal-physiotherapy-in-patients-with-reverse-shoulder-prosthesis-100543536","NCT06357143","Efficacy of Early Multimodal Physiotherapy in Patients With Reverse Shoulder Prosthesis","Efficacy of Early Multimodal Physiotherapy in Patients With Reverse Shoulder Prosthesis: a Randomized Controlled Trial.","Inclusion Criteria:\n\n* Adults with a reverse shoulder prosthesis.\n* Age between 18 and 90 years.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Language or cultural barriers.\n* Other upper limb injury.\n* Treatment that affect physical activity capacity.","90 Years",{"count":151,"type":21},[59],"The present study try to evaluate the effectivenness of an early intervention program based on multimodal physiotherapy and focused on therapeutic exercise to improve the results of patients with a reverse shoulder phrostesis. This trial will be a randomized controlled trial with parallel groups, and outcomes variables will include psychometric properties through the use of specific questionnaries, and laboratory variables such as strength with a dynamometer, range of movement with a goniometer, muscle mass with an ultrasound, and kinematic parameters with inertial sensors. This study aims to develop an original intervention program in order to try to establish new protocols in the management of these patients.",[254,255],"Shoulder Fractures","Prosthesis User",{"date":257,"type":38},"2026-04-08",{"date":259,"type":38},"2025-09-01",{"date":261,"type":21},"2027-12",{"name":44,"class":45},{"id":264,"slug":265,"hasResults":11,"nctId":266,"briefTitle":267,"officialTitle":268,"acronym":4,"eligibilityCriteria":269,"healthyVolunteers":16,"sex":270,"minAge":271,"maxAge":91,"enrollmentInfo":272,"targetDuration":4,"studyType":57,"phases":274,"briefSummary":275,"conditions":276,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":280,"lastUpdatePostDateStruct":281,"startDateStruct":283,"completionDateStruct":284,"leadSponsor":286,"locationsCount":46},"100629248","foot-and-ankle-strengthening-program-to-improve-physical-function-in-menopausal-women-100629248","NCT07472205","Foot and Ankle Strengthening Program to Improve Physical Function in Menopausal Women","Randomized Clinical Trial of the Effects of a 12-Week Foot and Ankle Strengthening Program on Physical Function and Quality of Life in Menopausal Women","Inclusion Criteria:\n\n* Women aged between 45 and 65 years.\n* Postmenopausal status defined as at least 12 consecutive months of amenorrhea.\n* Low or moderate physical activity level assessed using the International Physical Activity Questionnaire (IPAQ).\n* Ability to understand study instructions and complete questionnaires in Spanish.\n* Willingness to participate in the study and sign informed consent.\n\nExclusion Criteria:\n\n* Neurological disorders affecting gait or motor control.\n* Lower limb surgery within the previous 6 months.\n* Active painful pathology of the foot or ankle that could interfere with the intervention or measurements.\n* Cognitive impairment limiting understanding or execution of the protocol.\n* Current participation in specific foot or ankle strengthening programs.\n* Habitual vigorous physical activity or participation in structured lower limb strength training programs within the previous three months.","FEMALE","45 Years",{"count":273,"type":21},70,[59],"This randomized controlled trial will evaluate the effects of a 12-week foot and ankle strengthening program on physical function and health-related quality of life in menopausal women.\n\nMenopause is associated with hormonal changes that may negatively affect muscle strength, balance, and functional capacity, potentially leading to reduced mobility and increased risk of falls. Although exercise interventions have demonstrated benefits in this population, most programs focus on global lower-limb training and rarely target the foot and ankle complex, which plays a key role in postural stability and gait propulsion.\n\nApproximately 60 menopausal women aged 45-65 years will be randomly assigned to either an intervention group performing a structured foot and ankle strengthening program or a control group maintaining their usual physical activity. The intervention will last 12 weeks and will include one supervised weekly session and four home-based sessions.\n\nThe primary outcome will be ankle plantarflexion isometric strength measured by hand-held dynamometry. Secondary outcomes will include ankle strength in other directions, intrinsic foot muscle function, gait speed, spatiotemporal gait parameters, balance, foot-related functional status, and health-related quality of life.",[277,278,279],"Menopause","Musculoskeletal Function","Physical Function","2026-03-10",{"date":282,"type":38},"2026-03-16",{"date":137,"type":21},{"date":285,"type":21},"2027-01-31",{"name":44,"class":45},{"id":288,"slug":289,"hasResults":11,"nctId":290,"briefTitle":291,"officialTitle":292,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":293,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":295,"conditions":296,"keywords":297,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":299,"lastUpdatePostDateStruct":300,"startDateStruct":302,"completionDateStruct":304,"leadSponsor":306,"locationsCount":46},"100625319","thumb-muscle-activation-during-first-dorsal-interosseous-exercise-in-thumb-base-osteoarthritis-100625319","NCT07421089","Thumb Muscle Activation During First Dorsal Interosseous Exercise in Thumb Base Osteoarthritis","A Between-Group Comparison of First Dorsal Interosseous and Abductor Pollicis Longus Muscle Activation During First Dorsal Interosseous Exercise in Individuals With and Without Thumb Base Osteoarthritis",{"count":294,"type":21},60,"The aim of this study is to investigate whether there are differences in muscle activation of the First Dorsal Interosseous (FDI) and the Abductor Pollicis Longus (APL) between individuals with and without trapeziometacarpal osteoarthritis (TMC OA) of the thumb. The study also seeks to identify which exercises are most effective for activating these muscles, in order to inform rehabilitation strategies for patients.\n\nThe FDI has been defined as a key stabilizer of the thumb TMC joint. However, the literature reports various protocols for FDI activation and limited information on APL behavior during these exercises. OA TMC of the thumb can cause pain, decreased thumb strength, impaired hand function, and difficulty performing activities of daily living (ADLs). Appropriate rehabilitation is essential to maintain muscle function, limit joint degeneration, and improve hand performance; however, the exercises that optimally activate the FDI and APL muscles are not yet established.\n\nParticipants will perform a series of standardized exercises and functional tasks designed to activate the FDI and APL muscles. Exercises include FDI strengthening with elastic bands in different hand positions (palmar and ulnar support), as well as exercises with the thumb in greater abduction. Functional tasks simulating everyday activities (e.g., turning a key, picking up a coin, writing, squeezing a tube of toothpaste, and holding a glass of water) will also be performed. Muscle activity will be recorded using surface electromyography (sEMG) during all tasks.\n\nAdults aged 40 years and older, both men and women, with TMC osteoarthritis and healthy controls without osteoarthritis will be invited to participate.\n\nResearchers will measure the activation patterns of the FDI and APL muscles during the exercises and functional tasks. The study aims to identify exercises that optimally activate these muscles, providing evidence to guide the rehabilitation of patients with thumb base osteoarthritis.",[26],[28,298,30,31,32],"trapeziometacarpal osteoarthritis","2026-02-16",{"date":301,"type":38},"2026-02-19",{"date":303,"type":21},"2026-01-28",{"date":305,"type":21},"2026-08",{"name":44,"class":45},{"id":308,"slug":309,"hasResults":11,"nctId":310,"briefTitle":311,"officialTitle":312,"acronym":313,"eligibilityCriteria":314,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":315,"enrollmentInfo":316,"targetDuration":4,"studyType":57,"phases":317,"briefSummary":318,"conditions":319,"keywords":323,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":328,"lastUpdatePostDateStruct":329,"startDateStruct":330,"completionDateStruct":332,"leadSponsor":334,"locationsCount":4},"100621522","home-based-auricular-transcutaneous-vagus-nerve-stimulation-tvns-for-sleep-quality-and-psycho-academic-outcomes-in-health-sciences-students-100621522","NCT07371715","Home-Based Auricular Transcutaneous Vagus Nerve Stimulation (tVNS) for Sleep Quality and Psycho-Academic Outcomes in Health Sciences Students","Efficacy, Safety, and Feasibility of a Home-Based Auricular Transcutaneous Electrical Stimulation Intervention Using a Low-Frequency TENS-Like Device to Improve Sleep Quality and Psycho-Academic Outcomes in Health Sciences Students: A Randomized Controlled Pilot Study","NEUROSLEEP","Inclusion Criteria:\n\n* Aged 18 to 35 years.\n* Undergraduate student enrolled in a Health Sciences degree program.\n* Poor sleep quality defined as PSQI \\> 7.\n* Meets diagnostic criteria for primary insomnia according to ICSD-3.\n* Ability to understand study procedures and provide written informed consent.\n* Willing and able to self-administer the intervention at home and complete study questionnaires.\n\nExclusion Criteria:\n\n* Current severe psychiatric disorder or ongoing psychotherapy treatment.\n* Neurological disorders (e.g., epilepsy).\n* Cardiac arrhythmias or implanted cardiac devices (e.g., pacemaker).\n* Current use of medications that significantly affect sleep (e.g., hypnotics or anxiolytics), unless stable and approved by the investigator.\n* Pregnancy.\n* Ear infection, skin lesions, or dermatologic condition preventing electrode placement.\n* Hypersensitivity or intolerance to electrical stimulation.\n* Participation in another clinical trial within the last 30 days.","35 Years",{"count":294,"type":21},[59],"This study aims to evaluate the efficacy, safety, and feasibility of a home-based auricular transcutaneous vagus nerve stimulation (tVNS) program in Health Sciences university students with poor sleep quality. Participants will be randomly assigned (1:1) to receive either active auricular stimulation (cymba conchae\u002Ftragus) or a control stimulation applied to the earlobe. The intervention will be self-administered at home using a low-frequency TENS-like device for 60 minutes per session, 5 sessions per week for 3 weeks. Sleep quality will be primarily assessed using the Pittsburgh Sleep Quality Index (PSQI) before and after the intervention. Secondary outcomes include insomnia severity, daytime sleepiness, perceived stress, anxiety, quality of life, and psycho-academic outcomes.",[320,321,322],"Sleep Disturbances","Insomnia","Stress",[324,325,326,327],"Transcutaneous Vagus Nerve Stimulation","sleep quality","Auricular Stimulation","university students","2026-01-23",{"date":303,"type":38},{"date":331,"type":21},"2026-03-01",{"date":333,"type":21},"2026-06-01",{"name":44,"class":45},{"id":336,"slug":337,"hasResults":11,"nctId":338,"briefTitle":339,"officialTitle":339,"acronym":340,"eligibilityCriteria":341,"healthyVolunteers":11,"sex":17,"minAge":342,"maxAge":343,"enrollmentInfo":344,"targetDuration":4,"studyType":57,"phases":346,"briefSummary":347,"conditions":348,"keywords":350,"overallStatus":164,"whyStopped":4,"lastUpdateSubmitDate":357,"lastUpdatePostDateStruct":358,"startDateStruct":360,"completionDateStruct":362,"leadSponsor":364,"locationsCount":365},"100509760","effectiveness-and-implementation-of-a-digital-intervention-for-pediatric-chronic-pain-co-designed-with-patients-100509760","NCT05917626","Effectiveness and Implementation of a Digital Intervention for Pediatric Chronic Pain Co-designed With Patients","Digital SPA","Inclusion Criteria:\n\n* Adolescents age 12-17 years\n* Has had non-oncologic chronic pain for at least 3 months (e.g., abdominal pain, headache or musculoskeletal pain)\n* Has Internet access\n* One parent is willing to participate (and both give consent for their child to participate)\n\nExclusion Criteria:\n\n* Diagnosis of a comorbid serious health condition (e.g., cancer)\n* Parent or child does not speak or read Spanish\n* Active psychosis or suicidal ideation","12 Years","17 Years",{"count":345,"type":21},195,[59],"Children and adolescents with chronic pain often lack a proper diagnosis and treatment. Research has shown that, if left untreated, it usually doesn't resolve and continues through adulthood.\n\nThe goal of this multi-phase study is to co-develop (with patients), test, and implement a smartphone app called \"Digital Solution for Pain in Adolescents\" (Digital SPA) which can provide pain management resources to children with chronic pain and their parents, preventing future disability.\n\nParticipants will: participate in individual and group interviews, respond to questionnaires online and try a smartphone app.",[349],"Chronic Pain",[351,352,353,354,355,356],"Chronic pain","Adolescents","Digital Health","Psychological Intervention","Co-development","Implementation","2025-12-05",{"date":359,"type":38},"2025-12-15",{"date":361,"type":38},"2023-05-05",{"date":363,"type":21},"2027-10",{"name":44,"class":45},6,{"id":367,"slug":368,"hasResults":11,"nctId":369,"briefTitle":370,"officialTitle":370,"acronym":4,"eligibilityCriteria":371,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":372,"enrollmentInfo":373,"targetDuration":4,"studyType":57,"phases":375,"briefSummary":376,"conditions":377,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":381,"lastUpdatePostDateStruct":382,"startDateStruct":384,"completionDateStruct":386,"leadSponsor":388,"locationsCount":4},"100605659","analysis-of-neuromodulation-as-a-complementary-treatment-to-evidence-based-clinical-intervention-in-subjects-with-musculoskeletal-pathology-of-the-upper-limb-a-double-blind-randomized-clinical-trial-100605659","NCT07165392","Analysis of Neuromodulation as a Complementary Treatment to Evidence-based Clinical Intervention in Subjects With Musculoskeletal Pathology of the Upper Limb: a Double-blind Randomized Clinical Trial","Inclusion Criteria:\n\n* Participants in the study will be men and women of working age, diagnosed with musculoskeletal disorders of the upper limb, and who have not yet received physical therapy.\n\nExclusion Criteria:\n\n* Have undergone surgery.\n* Those who refuse to participate in this study.\n* Patients who present muscular atrophy in the upper limb due to a pathology of the latter.\n* Medical conditions that are contraindications for neuromodulation therapy","60 Years",{"count":374,"type":21},120,[59],"This project aims to analyze the use of neuromodulation within a treatment protocol for musculoskeletal conditions of the upper limb, as well as to determine the difference between two and three sessions per week. Study participants will be divided into four intervention groups: the first will receive two sessions per week for a period of six months, while the second will receive three sessions per week for the same period. The treatment protocol will consist of therapeutic physical exercise focused on the muscles and joints of the lower limb, stretching of the involved muscles, and neuromodulation of the brachial plexus nerve root, which innervates the affected structures. The third and fourth intervention groups will receive the same treatment as mentioned above, but without neuromodulation. The third group will receive three sessions per week, while the second group will receive two sessions per week. Two different types of measurement variables will be used: objective variables will be used to measure range of motion and muscle strength. Subjective variables will also be used through validated questionnaires, covering physical activity, health-related quality of life, upper limb function, and a visual analog scale for pain perception.",[378,379,380],"Neuromodulation","Upper Limb","Musculoskeletal Disorders","2025-09-02",{"date":383,"type":38},"2025-09-10",{"date":385,"type":21},"2025-10-01",{"date":387,"type":21},"2027-03-31",{"name":44,"class":45},{"id":390,"slug":391,"hasResults":11,"nctId":392,"briefTitle":393,"officialTitle":393,"acronym":4,"eligibilityCriteria":394,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":372,"enrollmentInfo":395,"targetDuration":4,"studyType":57,"phases":397,"briefSummary":398,"conditions":399,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":381,"lastUpdatePostDateStruct":401,"startDateStruct":402,"completionDateStruct":403,"leadSponsor":404,"locationsCount":4},"100605658","analysis-of-neuromodulation-as-a-complementary-treatment-to-evidence-based-clinical-intervention-in-subjects-with-musculoskeletal-pathology-of-the-lower-limb-a-double-blind-randomized-clinical-trial-100605658","NCT07165379","Analysis of Neuromodulation as a Complementary Treatment to Evidence-based Clinical Intervention in Subjects With Musculoskeletal Pathology of the Lower Limb: a Double-blind Randomized Clinical Trial","Inclusion Criteria:\n\n* Participants in the study will be men and women of working age, diagnosed with musculoskeletal disorders of the lower limb, and who have not yet received physical therapy.\n\nExclusion Criteria:\n\n* Have undergone surgery.\n* Those who refuse to participate in this study.\n* Patients who present muscular atrophy in the lower limb due to a pathology of the latter.\n* Medical conditions that are contraindications for neuromodulation therapy",{"count":396,"type":21},64,[59],"This project aims to analyze the use of neuromodulation within a treatment protocol for musculoskeletal conditions of the lower limb, as well as to determine the difference between two and three sessions per week. Study participants will be divided into four intervention groups: the first will receive two sessions per week for a period of six months, while the second will receive three sessions per week for the same period. The treatment protocol will consist of therapeutic physical exercise focused on the muscles and joints of the lower limb, stretching of the involved muscles, and neuromodulation of the nerve root of the lumbosacral plexus, which innervates the affected structures. The third and fourth intervention groups will receive the same treatment as mentioned above, but without neuromodulation. The third group will receive three sessions per week, while the second group will receive two sessions per week. Two different types of measurement variables will be used: objective variables will be used to measure range of motion and muscle strength. Subjective variables will also be used through validated questionnaires, covering physical activity, health-related quality of life, lower limb function, and a visual analog scale for pain perception.",[378,400,380],"Lower Limb",{"date":383,"type":38},{"date":385,"type":21},{"date":387,"type":21},{"name":44,"class":45},{"id":406,"slug":407,"hasResults":11,"nctId":408,"briefTitle":409,"officialTitle":409,"acronym":4,"eligibilityCriteria":410,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":372,"enrollmentInfo":411,"targetDuration":4,"studyType":57,"phases":412,"briefSummary":413,"conditions":414,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":417,"lastUpdatePostDateStruct":418,"startDateStruct":420,"completionDateStruct":421,"leadSponsor":422,"locationsCount":4},"100600879","analysis-of-hyperthermia-as-an-adjunctive-treatment-to-evidence-based-clinical-intervention-in-subjects-with-plantar-fasciitis-a-double-blind-randomized-clinical-trial-100600879","NCT07103226","Analysis of Hyperthermia as an Adjunctive Treatment to Evidence-based Clinical Intervention in Subjects With Plantar Fasciitis: a Double-blind Randomized Clinical Trial","Inclusion Criteria:\n\n* Have a diagnosis confirmed by performing an ultrasonography of Plantar Fascitis\n* Have not yet received physiotherapy treatment.\n\nExclusion Criteria:\n\n* Have undergone surgery.\n* Those who refuse to participate in this study.\n* Patients with muscle atrophy due to plantar fasciitis.\n* Medical conditions that are contraindications for hyperthermia therapy.",{"count":396,"type":21},[59],"This project aims to analyze the use of hyperthermia within a treatment protocol for plantar fasciitis, as well as to determine the difference between two and three sessions per week. Study participants will be divided into four intervention groups: the first will receive two sessions per week for a period of six months, while the second will receive three sessions per week for the same period. The treatment protocol will consist of therapeutic physical exercise focused on the foot muscles and stretching the plantar fascia and posterior chain, hyperthermia on the plantar fascia insertion area in the calcaneus and adjacent areas, and the use of an orthotic insole used for walking. The third and fourth intervention groups will receive the same treatment as mentioned above, but without hyperthermia. The third group will receive three sessions per week, while the second group will receive two sessions per week. Two different types of measurement variables will be used: objective variables will be used to measure local pain using an algometer, assess ankle joint range of motion, and use ultrasound imaging techniques. Subjective variables will also be used through validated questionnaires, which will address physical activity, perceived functional limitations in patients with lower limb pathologies, lower limb functional assessment, and a visual analogue scale for pain perception.",[415,416],"Plantar Fascia","Hyperthermia","2025-08-01",{"date":419,"type":38},"2025-08-05",{"date":417,"type":21},{"date":387,"type":21},{"name":44,"class":45},{"id":424,"slug":425,"hasResults":11,"nctId":426,"briefTitle":427,"officialTitle":427,"acronym":4,"eligibilityCriteria":428,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":372,"enrollmentInfo":429,"targetDuration":4,"studyType":57,"phases":430,"briefSummary":431,"conditions":432,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":434,"lastUpdatePostDateStruct":435,"startDateStruct":436,"completionDateStruct":437,"leadSponsor":439,"locationsCount":4},"100600598","analysis-of-hyperthermia-as-an-adjunctive-treatment-to-evidence-based-clinical-intervention-in-subjects-with-bursitis-a-double-blind-randomized-clinical-trial-100600598","NCT07099573","Analysis of Hyperthermia as an Adjunctive Treatment to Evidence-based Clinical Intervention in Subjects With Bursitis: a Double-blind Randomized Clinical Trial","Inclusion Criteria:\n\n* Have a diagnosis confirmed by performing an imaging test of Bursitis\n* Have not yet received physiotherapy treatment.\n\nExclusion Criteria:\n\n* Have undergone surgery.\n* Those who refuse to participate in this study.\n* Patients with muscle atrophy.\n* Medical conditions that are contraindications for hyperthermia therapy.",{"count":374,"type":21},[59],"This project aims to analyze the use of hyperthermia within a bursitis treatment protocol, as well as to determine the difference between two and three sessions per week. Study participants will be divided into four intervention groups: the first will receive two sessions per week for a period of six months, while the second will receive three sessions per week for the same period. The treatment protocol will consist of therapeutic physical exercise focused on the affected joint, stretching of the involved muscles, and the application of hyperthermia to the bursa and surrounding areas. The third and fourth intervention groups will receive the same treatment as mentioned above, but without hyperthermia. The third group will receive three sessions per week, while the second group will receive two sessions per week. Two different types of measurement variables will be used: on the one hand, the objective variable will be measurement and assessment of the bursa using ultrasound imaging. Subjective measurement variables will also be used through validated questionnaires, which will address physical activity, perceived functional limitations, and the visual analog scale for pain perception.",[433,416],"Bursitis","2025-07-25",{"date":417,"type":38},{"date":417,"type":21},{"date":438,"type":21},"2026-04-30",{"name":44,"class":45},{"id":441,"slug":442,"hasResults":11,"nctId":443,"briefTitle":444,"officialTitle":444,"acronym":445,"eligibilityCriteria":446,"healthyVolunteers":16,"sex":17,"minAge":447,"maxAge":222,"enrollmentInfo":448,"targetDuration":4,"studyType":57,"phases":450,"briefSummary":451,"conditions":452,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":454,"lastUpdatePostDateStruct":455,"startDateStruct":457,"completionDateStruct":459,"leadSponsor":461,"locationsCount":46},"100596575","short--and-long-term-effects-of-whole-body-photobiomodulation-in-type-ii-diabetes-patients-a-protocol-for-a-controlled-clinical-trial-100596575","NCT07047248","Short- and Long-Term Effects of Whole-Body Photobiomodulation in Type II Diabetes Patients: A Protocol for a Controlled Clinical Trial","PBM","Inclusion Criteria:\n\n* Adults aged 30 to 70 years.\n* Diagnosed with Type 2 Diabetes Mellitus (T2DM) according to the American Diabetes Association (ADA) criteria.\n* HbA1c levels between 6.5% and 10% at screening.\n* Stable diabetes management regimen (medications and lifestyle) for at least three months prior to enrollment\n\nExclusion Criteria:\n\n* Presence of severe diabetic complications (e.g., end-stage renal disease, proliferative diabetic retinopathy).\n* History of photosensitivity or medical conditions exacerbated by light exposure.\n* Use of medications or supplements known to significantly alter glucose metabolism, other than current stable diabetes management.\n* Pregnant or lactating women.","30 Years",{"count":449,"type":21},44,[59],"The development of an integral and global treatment to improve the quality of life in those withType II Diabetes Patients is challenging, thus a whole body Photobiomodulation (PBM) therapy program is proposed as an effective option.",[453],"Type II Diabetes Mellitus","2025-06-27",{"date":456,"type":38},"2025-07-02",{"date":458,"type":21},"2025-08-30",{"date":460,"type":21},"2026-01-30",{"name":44,"class":45},{"id":463,"slug":464,"hasResults":11,"nctId":465,"briefTitle":466,"officialTitle":467,"acronym":468,"eligibilityCriteria":469,"healthyVolunteers":11,"sex":17,"minAge":470,"maxAge":18,"enrollmentInfo":471,"targetDuration":4,"studyType":57,"phases":473,"briefSummary":474,"conditions":475,"keywords":477,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":480,"lastUpdatePostDateStruct":481,"startDateStruct":483,"completionDateStruct":485,"leadSponsor":487,"locationsCount":46},"100549793","effects-obtained-at-manual-function-after-applying-anodic-transcranial-direct-current-stimulation-tcds-in-children-with-spastic-hemiparetic-cerebral-palsy-100549793","NCT06438666","Effects Obtained at Manual Function After Applying Anodic Transcranial Direct Current Stimulation (tCDS) in Children With Spastic Hemiparetic Cerebral Palsy","A Quasi Experimental Study About the Effects Obtained at Manual Function After Applying Anodic Transcranial Direct Current Stimulation in Children With Spastic Hemiparetic Cerebral Palsy","PeditCDS","Inclusion Criteria:\n\n* Children between 14-18 years old.\n* Children with spastic hemiparetic cerebral palsy diagnosis.\n* Children with a cognitive level high enough to understand and to do the activities to value them.\n* Children hemodynamically stable.\n* Children forming part of levels II-IV of the Manual Ability Classification System (MACS).\n\nExclusion Criteria:\n\n* Children with defibrillator.\n* Children with pacemaker.\n* Children with cerebral stimulator.\n* Children with intracranial metallic implants.\n* Children with opened cranial after clambering.\n* Children that receive another treatment (pharmacological or physiotherapical) that could interfere or disrupt the results.\n* Another circumstance where the electrotherapy treatment is contraindicated.","14 Years",{"count":472,"type":21},20,[59],"Spastic Hemiparetic Cerebral Palsy (SHCP) uses to limit the manual function. Using anodic transcranial direct current stimulation, it is possible to activate certain cerebral areas depending on where the electrodes are. This study will use this kind of stimulation on the contralateral primary motor cortex of the affected upper limb and analyze the effects.",[476],"Hemiparetic Cerebral Palsy",[478,479,379],"Cerebral Palsy","Transcranial Direct Current Stimulation","2025-06-14",{"date":482,"type":38},"2025-06-18",{"date":484,"type":21},"2025-10-20",{"date":486,"type":21},"2027-03-20",{"name":44,"class":45},{"id":489,"slug":490,"hasResults":11,"nctId":491,"briefTitle":492,"officialTitle":493,"acronym":4,"eligibilityCriteria":494,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":372,"enrollmentInfo":495,"targetDuration":4,"studyType":57,"phases":497,"briefSummary":498,"conditions":499,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":502,"lastUpdatePostDateStruct":503,"startDateStruct":505,"completionDateStruct":507,"leadSponsor":508,"locationsCount":4},"100588505","analysis-of-hyperthermia-as-a-complementary-treatment-to-evidence-based-clinical-intervention-in-subjects-with-carpal-tunnel-syndrome-100588505","NCT06942273","Analysis of Hyperthermia as a Complementary Treatment to Evidence-based Clinical Intervention in Subjects With Carpal Tunnel Syndrome:","Analysis of Hyperthermia as a Complementary Treatment to Evidence-based Clinical Intervention in Subjects With Carpal Tunnel Syndrome: a Double-blind Randomized Clinical Trial.","Inclusion Criteria:\n\n* Have a diagnosis confirmed by performing an electromyography of Carpal Tunnel Syndrome\n* Have not yet received physiotherapy treatment.\n\nExclusion Criteria:\n\n* Have undergone surgery.\n* Those who refuse to participate in this study.\n* Patients with muscle atrophy due to CTS.\n* Medical conditions that are contraindications for hyperthermia therapy.",{"count":496,"type":21},160,[59],"This project aims to analyze the use of hyperthermia within a treatment protocol for Carpal Tunnel Syndrome (CTS), as well as to determine the difference between two and three sessions per week. Study participants will be divided into four intervention groups: the first will receive two sessions per week for a period of six months, while the second will receive three sessions per week for the same period. The treatment protocol will consist of therapeutic physical exercise focused on the hand flexor muscles and neural stretching, the application of hyperthermia to the carpal tunnel and adjacent areas, and the use of a night splint. The third and fourth intervention groups will receive the same treatment as mentioned above, but without hyperthermia. The third group will receive three sessions per week, while the second group will receive two sessions per week. Two different types of measurement variables will be used: objective variables will be used to measure hand flexor muscle strength and wrist free range of motion. Subjective variables will also be used through validated questionnaires covering physical activity, perceived functional limitations, upper limb functional assessment, neuropathic pain, and a visual analogue scale for pain perception.",[500,416,501],"Carpal Tunnel Syndrome (CTS)","Frequency of Therapy","2025-04-16",{"date":504,"type":38},"2025-04-24",{"date":506,"type":21},"2025-05-01",{"date":438,"type":21},{"name":44,"class":45},{"id":510,"slug":511,"hasResults":11,"nctId":512,"briefTitle":513,"officialTitle":513,"acronym":4,"eligibilityCriteria":514,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":515,"targetDuration":4,"studyType":57,"phases":517,"briefSummary":518,"conditions":519,"keywords":520,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":524,"lastUpdatePostDateStruct":525,"startDateStruct":527,"completionDateStruct":529,"leadSponsor":531,"locationsCount":4},"100580071","use-of-virtual-reality-to-improve-sensorimotor-function-in-patients-with-traumatic-wrist-and-hand-injuries-100580071","NCT06832527","Use of Virtual Reality to Improve Sensorimotor Function in Patients with Traumatic Wrist and Hand Injuries","Inclusion Criteria:\n\n* Adult (equal or more than 18 y\u002Fo).\n* Suffering wrist injury\n* Agree and sign informed consent.\n\nExclusion Criteria:\n\n* Not had suffered a wrist injury\n* Suffer from any mental, cognitive, neurological or musculoskeletal disorder\n* Have cervical pathology\u002Fimpairment\n* Have visual or balance problems",{"count":516,"type":21},79,[59],"The goal of this randomized clinical trial is to compare how the incorporation of Virtual Reality could influence in proprioception, kinesiophobia, functionality and catastrophism in people that are undergoing a rehabilitation treatment after a wrist fracture. The principal questions it aims to answer are:\n\n* Evaluate the effect of using virtual reality added to standard rehabilitation of wrist injuries in proprioception impairment.\n* Evaluate the effect of using virtual reality on psychological factors as kinesiophobia and catastrofism.\n* Evaluate the effect of using virtual reality in functionality on wrist-injured patients.\n\nIntervention will be:\n\n* Control group: participants of this group will receive conventional rehabilitation of the wrist, plus a specific proprioceptive exercise program.\n* Experimental group: participants of this group will receive the same treatment as the control group but adding virtual reality games at the end of the session.\n\nResearchers will compare control and experimental group to see if an implantation of Virtual Reality could had benefits on function, kinesiophobia, catastrofism and proprioception.",[155],[521,522,523],"wrist injury","proprioception","virtual reality","2025-02-18",{"date":526,"type":38},"2025-02-20",{"date":528,"type":21},"2025-02-25",{"date":530,"type":21},"2025-07",{"name":44,"class":45},{"id":533,"slug":534,"hasResults":11,"nctId":535,"briefTitle":536,"officialTitle":537,"acronym":538,"eligibilityCriteria":539,"healthyVolunteers":11,"sex":270,"minAge":18,"maxAge":4,"enrollmentInfo":540,"targetDuration":4,"studyType":57,"phases":542,"briefSummary":543,"conditions":544,"keywords":548,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":556,"lastUpdatePostDateStruct":557,"startDateStruct":559,"completionDateStruct":561,"leadSponsor":563,"locationsCount":46},"100524814","lymphatic-response-to-resistance-exercise-in-breast-cancer-survivors-100524814","NCT06113627","Lymphatic Response to Resistance Exercise in Breast Cancer Survivors","Prevention-Related Lymphatic Response to Resistance Exercise in Breast Cancer Survivors at Risk of Breast Cancer-Related Lymphedema","LinfoGYM","Inclusion Criteria:\n\n* Women diagnosed with breast cancer\n* Being of legal age\n* Histologically confirmed primary Breast Cancer (I-IIIA) (without the presence of metastasis) with a diagnosis in the last year\n* Unilateral involvement\n* Surgery for the tumor at least 6 weeks before the start of the intervention\n* WHO performance status of 0 (asymptomatic, complete and ambulatory activity)\n* Correct understanding of Spanish\n* Approval by signing the informed consent;\n* Mus be considered at risk for developing LACM: 1) Have undergone surgery that includes axillary dissection; 2) Have received or are undergoing regional lymph node radiation; 3) BMI \\>30 kg\u002Fm2. . These patients are considered to have stage 0, subclinical or latent according to the International Society of Lymphology (ISL) , since they will not present signs or symptoms, but lymphatic transport will be altered by the treatments themselves\n\nExclusion Criteria:\n\n* Women already diagnosed with LACM in stage I, II or III according to the ISL or if they present an L-Dex ratio \\> 10 or a difference in volume equal to or greater than 10% between both extremities\n* Suffer from or have been diagnosed with any other lymphatic-venous disease in the upper extremity, such as venous insufficiency, thrombosis or lipedema;\n* Suffer from conditions that prevent resistance exercise of the upper body\n* Participation in regular (\\>1 time\u002Fweek) and intense exercises involving the upper extremity during the last month\n* Suffer from heart disease\n* Inability to complete questionnaires;\n* A physical condition that prevents them from making hospital visits\n* Taking any drug that may affect the lymphatic and circulatory system, such as diuretics or corticosteroids\n* Women which presents some type of wound or infection on the skin.",{"count":541,"type":21},170,[59],"The objective of this study is 1) to study the acute and chronic effect of resistance therapeutic physical exercise (RTPE) in the prevention of breast cancer-related lymphedema (BCRL) in breast cancer survivors at risk using variables related to the lymphatic response; 2) Study the possible relationship between changes in body composition at a local and regional level and volume changes produced by RTPE in patients at risk of suffering from BCRL.",[545,546,547],"Breast Cancer Lymphedema","Survivorship","Lymphedema of Upper Limb",[549,550,545,551,552,553,554,555],"Breast Cancer","Lymphedema, Early-Onset","Exercise Therapy","Exercise Training","Acute Exercise","Exercise Movement Techniques","Physiotherapy (Techniques)","2023-10-30",{"date":558,"type":38},"2023-11-02",{"date":560,"type":21},"2024-08",{"date":562,"type":21},"2027-01-15",{"name":44,"class":45},""]