[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Missouri, Kansas City\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":206},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,51,82,115,145,178],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100636075","addressing-food-access-and-physical-activity-to-improve-diabetes-prevention-outcomes-among-underserved-african-americans-100636075",false,"NCT07560969","Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans","Inclusion Criteria:\n\n* Members of a participating church or user of a participating church's outreach services\n* Age 18 years or older\n* Prediabetic (score of 5 or higher in the National Diabetes Prevention Program Risk Score or (\\[body mass index \\> 24 or history of gestational diabetes\\] and (5.7-6.4 A1v, 100-125 mg\u002FdL fasting plasma glucose, or 140-149 mg\u002FdL oral glucose tolerance test)\n\nExclusion Criteria:\n\n* Individuals who are pregnant, breastfeeding or planning to become pregnant in the next year\n* Individuals with unsafe blood pressure levels (160 systolic or higher or 100 diastolic or higher) without a medical clearance firn\n* Individuals who are not able to engage in low-impact physical activity\n* Individuals who do not speak English\n* Individuals who live in a household with a participant in this study at a different church","ALL","18 Years",{"count":18,"type":19},408,"ESTIMATED","INTERVENTIONAL",[22],"NA","The goal of this clinical trial is to learn if an enhanced, culturally, socially, and structurally tailored Diabetes Prevention Program (E-DPP) can improve weight loss and related diabetes risk factors in African American adults with prediabetes living in low-income, socially vulnerable communities.\n\nThe main questions it aims to answer are:\n\n* Does the enhanced DPP (E-DPP) lead to greater percent weight loss at 6 and 12 months compared to the standard culturally tailored DPP (S-DPP)?\n* How do social determinants (e.g., food insecurity, stigma, access to resources) influence weight loss and engagement in lifestyle behaviors?\n\nResearchers will compare a standard culturally tailored DPP (S-DPP) to an enhanced DPP (E-DPP) to see if improving access to healthy food, physical activity, and community resources increases weight loss and improves diabetes-related outcomes.\n\nParticipants will\n\n1. Attend DPP sessions delivered in community settings (e.g., churches)\n2. Receive lifestyle education focused on diet, physical activity, and weight loss\n3. Engage in physical activity (including in-class exercise sessions \\[E-DPP only\\] and community-based options)\n4. Receive support for healthy eating, including food deliveries (\\[E-DPP only\\]), food selection guidance, and referrals to food assistance programs\n5. Receive information and support for accessing community resources for food and physical activity",[25,26,27,28],"Diabetes","Physical Activity","Food Security","Nutrition Security",[30,31,32,33,34,35,36,37],"diabetes","obesity","community-based participatory research","Weight loss","Cluster randomized trial","lifestyle change program","faith-based organizations","African American","NOT_YET_RECRUITING","2026-06-05",{"date":41,"type":42},"2026-06-09","ACTUAL",{"date":44,"type":19},"2027-01-04",{"date":46,"type":19},"2031-02-28",{"name":48,"class":49},"University of Missouri, Kansas City","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":15,"minAge":59,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":20,"phases":62,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":4},"100634812","rocking-chairs-as-post-operative-treatment-for-older-adults-after-hip-surgery-100634812","NCT07544550","Rocking Chairs as Post-operative Treatment for Older Adults After Hip Surgery","Feasibility and Acceptability of the Impact of a Rocking Chair Intervention on Recovery Compared to Standard Care of Stationary Chair on Older Adults After Elective Orthopedic Hip Surgery: A Randomized Controlled Trial","FAIRChair","Inclusion Criteria:\n\n* scheduled to undergo an elective primary total hip arthroplasty\n* Weigh less than 163kg (limit of rocking chair)\n* Able to consent\n* Able to rock with at least one leg\n\nExclusion Criteria:\n\n* Unable to sit in a chair for at least 30 minutes at a time\n* Hospitalized more than 24 hours after surgery\n* Cannot read and understand the English language\n* Planned disposition to rehabilitation facility or skilled nursing facility\n* Known vestibular dysfunction (such as Menieres, traumatic brain injury, vertigo)","65 Years",{"count":61,"type":19},60,[22],"Feasibility and acceptability randomized controlled trial exploring the use of a rocking chair after a total hip arthroplasty in adults who are aged 65 or older. Primary aims include its feasibility and acceptability; exploratory aims include the impact of rocking on pain, gastrointestinal effects, anxiety, ambulation, and additional healthcare visits.",[65],"Postoperative Care",[67,68,69,70,71,72,73],"older adults","hip arthroplasty","rocking chair","feasiblity","acceptability","recovery","intervention","2026-04-21",{"date":76,"type":42},"2026-04-27",{"date":78,"type":19},"2026-05-15",{"date":80,"type":19},"2026-10-31",{"name":48,"class":49},{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":90,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":20,"phases":93,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},"100462419","phase-2-social-determinants-and-a-diabetes-prevention-program-tailored-for-african-americans-100462419","NCT05301413","Social Determinants and a Diabetes Prevention Program Tailored for African Americans","Addressing Social Determinants of Health to Improve Diabetes Prevention Program Outcomes Among Underserved African Americans (FIT4ALL Project)","FIT4ALL","Inclusion Criteria:\n\n* Black\u002FAfrican American\n* Overweight (\\[BMI\\> 24); and\n* Diagnosed with prediabetes OR pre-diagnosed with gestational diabetes OR high risk result on prediabetes risk test\n\nExclusion Criteria:\n\n* Diagnosed with diabetes\n* Pregnant\n* Not fluent in English\n* Currently pregnant, planning a pregnancy in the next year, currently breastfeeding or have given birth in the last 6 months\n* Currently participating in a weight loss program\n* Currently have a medical condition that causes drastic weight loss\n* Bariatric weight loss surgery in last year\n* Cannot walk a 1-block distance without assistance and without stopping due to pain, tightness, or pressure in the chest\n* Had heart failure\n* Not willing to use a fitness tracker, wi-fi scale, and the internet\n* Not available in the evening one day each week to participate in a class",true,{"count":92,"type":19},360,[94],"PHASE2","African Americans (AAs) have rates of diabetes mellitus (DM) twice that of Whites and are disproportionately affected by leading risk factors for DM - obesity and low-income. A critical strategy in the battle against DM is the Diabetes Prevention Program (DPP), an evidence-based intervention that significantly delays or prevents Type 2 diabetes through the promotion of diet change, exercise and modest weight loss. However, weight loss from the DPP among AAs is about half that of White participants, and suboptimal AA attendance is a critical contributor. The investigators propose to conduct a study that will address social determinants (SD) that challenge DPP attendance with underserved African Americans from a safety net hospital. The investigators will examine DPP attendance and weight loss with participants randomized to 3 groups: standard DPP, a culturally-tailored DPP to address acceptability, and a culturally-tailored DPP enhanced to address socioeconomic-related barriers to DPP participation. This novel study is the first to tailor the DPP to address SD cultural and socioeconomic barriers that limit DPP attendance and reduce its effectiveness on outcomes. The proposed multidimensional, SD tailored DPP has great potential to be a feasible and scalable model to reduce DM risks among urban, African Americans and ultimately reduce DM disparities.",[97,98],"PreDiabetes","Overweight and Obesity",[37,100,101,102,103,33,104],"Prediabetes","Diabetes Prevention Program","Cultural tailoring","Linkage to care","Class attendance","RECRUITING","2025-05-20",{"date":108,"type":42},"2025-05-25",{"date":110,"type":42},"2022-07-20",{"date":112,"type":19},"2026-02-28",{"name":48,"class":49},2,{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":119,"acronym":4,"eligibilityCriteria":120,"healthyVolunteers":11,"sex":15,"minAge":121,"maxAge":122,"enrollmentInfo":123,"targetDuration":4,"studyType":20,"phases":125,"briefSummary":126,"conditions":127,"keywords":129,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":50},"100526721","group-cbt-in-parents-of-children-with-food-allergy-100526721","NCT06138431","Group CBT in Parents of Children With Food Allergy","Inclusion Criteria:\n\n1. Parent, age \\>18yrs\n2. All genders\n3. Child must be aged 18 months - 17yrs with serious food allergy(ies), medically diagnosed\n4. Meets cut-offs for anxiety and\u002For depression on the Hospital Anxiety and Depression Scale (need to define)\n5. Parent can be on stable doses of antidepressants or anxiety medications but all doses must remain stable for 1 month before study and during it as well as for 2 months after the groups are completed: to fill out final questionnaires\n6. Both parents of a child may enroll but will need to agree to fill out all questionnaires separately without discussing them with each other\n\nExclusion Criteria:\n\n1. Parental history of recent suicidal ideation \u002F suicide attempt\n2. Current Suicidal ideation\n3. Current substance abuse\n4. Parent currently in psychiatric treatment and medications being adjusted\n5. Using OTC anxiety or depression relief, or CBD or medical marijuana\n6. Parent receiving other therapies or group supports\n7. Parent unable to attend 6 consecutive weekly group sessions and fill out questionnaires online also 2 months later or does not have access to WiFi.","18 Months","17 Years",{"count":124,"type":19},10,[22],"Parents of children with food allergies that are medically established will be able to participate in 6 one-hour weekly virtual Cognitive Behavioral Therapy (CBT) groups, and outcomes will be measured for anxiety, depression and quality of life. Possible benefits include improvement in psychological functioning and quality of life of families, as well as improved understanding of the use of group Cognitive Behavioral Therapy (CBT) for parents of children with medically established food allergies.",[128],"Parents",[130,131,132,133,134,135,136],"parents","children","food","allergies","CBT","cognitive","therapy","2025-04-13",{"date":139,"type":42},"2025-04-16",{"date":141,"type":42},"2023-06-19",{"date":143,"type":19},"2025-12-31",{"name":48,"class":49},{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":149,"acronym":150,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":152,"minAge":16,"maxAge":4,"enrollmentInfo":153,"targetDuration":4,"studyType":155,"phases":4,"briefSummary":156,"conditions":157,"keywords":159,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":175,"leadSponsor":177,"locationsCount":50},"100555864","the-heart-outcomes-in-pregnancy-expectations-for-mom-and-baby-study-100555864","NCT06517628","The Heart Outcomes in Pregnancy Expectations for Mom and Baby Study","HOPE","Inclusion:\n\nMust have one or more condition(s) within the 6 following categories - Repaired or Unrepaired\n\n* Congenital or structural heart disease\n* Aortopathies\n* Arrhythmias\n* Cardiomyopathies and Heart Failure\n* Coronary disease\n* Other (Current endocarditis or history of endocarditis, Pericarditis, Pericardial effusion - Moderate or Large, Pericardial constriction, Pulmonary hypertension (all types) defined as mean pulmonary artery systolic pressure of \\>20 mmHg by right heart catheterization or pulmonary hypertension estimated in the severe range by echo)\n\nExclusion Criteria\n\n* Unable to participate in telephone follow-up\n* Too hard of hearing to do follow-up by telephone or deaf\n* Incarcerated prisoner\n* History of dementia.\n* Subjects without a way for contact by telephone for follow-up\n* Refused participation in the study\n* Unable to consent for self\n* Traumatic Aortic Disease\n* Peripartum cardiomyopathy diagnosed in current pregnancy","FEMALE",{"count":154,"type":19},1000,"OBSERVATIONAL","This is a prospective, observational study which is evaluating the obstetrical, neonatal, and cardiovascular outcomes of 1000 pregnant people with known heart disease to define how best to structure cardio-obstetrics care to optimize outcomes.",[158],"Pregnancy Complications, Cardiovascular",[160,161,162,163,164,165,166,167,168,169],"Pregnancy, cardio-obstetrics","Structures of Care","Quality of Care","Disparities","Heart disease in pregnancy","Pregnancy complications","Adverse pregnancy outcomes","Major adverse cardiac events","Neonatal adverse events","Quality of life","2025-01-16",{"date":172,"type":42},"2025-01-20",{"date":174,"type":42},"2025-01-14",{"date":176,"type":19},"2028-06-30",{"name":48,"class":49},{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":183,"acronym":4,"eligibilityCriteria":184,"healthyVolunteers":11,"sex":15,"minAge":185,"maxAge":186,"enrollmentInfo":187,"targetDuration":4,"studyType":20,"phases":189,"briefSummary":190,"conditions":191,"keywords":194,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":200,"lastUpdatePostDateStruct":201,"startDateStruct":203,"completionDateStruct":204,"leadSponsor":205,"locationsCount":50},"100405196","simultaneous-recumbent-cycling-and-cognitive-training-100405196","NCT04556227","Simultaneous Recumbent Cycling and Cognitive Training","Simultaneous Recumbent Cycling and Cognitive Training on Cognition in Intensive Care Unit Survivors: a Randomized Control Trial","Inclusion Criteria:\n\n* Age 45-64 years\n* Admitted to medical or surgical ICUs (SLH \\& TMC) for \\>24 hours\n* English-speaking\n* Discharged home\n* Able to provide consent\n* Access to a telephone\n* One or more delirium episode in ICU (positive CAM-ICU).\n\nExclusion Criteria:\n\n* Cancer diagnosis with short life expectancy determined by the Primary Care Provider (unable to complete the study within time frame)\n* Chemotherapy (drug-induced impaired cognition)\n* Diagnosed vascular dementia or other neurodegenerative diseases (e.g. Alzheimer or Parkinson disease)\n* Documented alcohol consumption ≥5 drinks\u002Fday (withdrawal delirium tremens)\n* Corrected vision\\\u003C20\u002F80 Snellen chart (unable to do cognitive exercises on the tablet)\n* Examiner rated low hearing or communicative ability that would interfere with intervention and assessments\n* Positive CAM-ICU (delirium) at hospital discharge\n* Unable to participate in rehabilitation (abnormal 6 min walk test)\n* Any physical condition preventing recumbent cycling\n* Recent documented history of drug abuse.","45 Years","64 Years",{"count":188,"type":19},50,[22],"Intensive care units (ICU) provide life-saving care for nearly five million people annually. Up to 80% of patients receiving care in an ICU experience at least one episode of delirium. Delirium, an acute episodic display of confused thinking and unawareness, predicts impaired cognition and accelerated cognitive decline which negatively impacts quality of life (QOL) long after hospital discharge. The average age of ICU patients is 52 years. These middle-age (MA) ICU survivors need cognitive interventions that are well planned, accessible, and effective to improve cognition and prevent accelerated decline so they can resume their previous QOL and enter older age with optimized cognitive function. Physical exercise and cognitive training independently improve cognition and emerging evidence indicates that combining these two approaches produces even greater effects on cognition. Community-based rehabilitation centers are accessible for MAICU survivors to engage in physical activity; cognitive training could easily be added. Approaches in which a patient engages in physical exercise and cognitive training concurrently is an understudied intervention for all ICU survivors, especially those who are middle-aged. Study aims are to investigate the feasibility and acceptability of a simultaneous recumbent cycling and cognitive training intervention (SRCCT) for MAICU survivors who experienced at least one delirium episode during their ICU stay. Feasibility will be determined by systematically evaluating research team training, participant recruitment, randomization, implementation, and intervention fidelity. Acceptability will be evaluated via a satisfaction, preferences, burden, and participant-suggested improvements survey. The SRCCT effect sizes will be calculated comparing multiple data point cognition scores between an SRCCT group and a usual care control group. Upon completion, investigators expect to understand the feasibility and acceptability of the SRCCT delivered in community-based rehabilitation centers, and the combined effect of SRCCT on cognition and QOL for middle-aged ICU survivors who experienced an episode of ICU delirium. The hypothesis is that study participants who engage in physical exercise and cognitive training concurrently will have a greater improvement in cognition and QOL than physical exercise training alone.",[192,193],"Delirium","Impaired Cognition",[195,196,197,198,199],"Intensive Care Unit","ICU-Survivors","Cognitive Training","Recumbent Cycling","Executive Functioning","2024-12-03",{"date":202,"type":42},"2024-12-06",{"date":200,"type":19},{"date":143,"type":19},{"name":48,"class":49},""]