[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Pecs\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":469},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,17,0,[8,47,61,90,119,155,179,210,236,260,289,316,339,368,393,414,445],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100053670","effect-of-aed-optimized-telephone-assisted-cpr-instructions-on-no-flow-time-and-chest-compression-fraction-100053670",false,"NCT07520877","Effect of AED-optimized Telephone-assisted CPR Instructions on No-flow Time and Chest Compression Fraction","Effect of AED-optimized Telephone-assisted CPR Instructions on No-flow Time and Chest Compression Fraction in a Single-rescuer Cardiac Arrest Scenario - a Randomized-controlled Simulation Study","Inclusion Criteria:\n\n* Adolescents and adults (≥16 years)\n* Healthcare professionals or laypersons\n* Voluntary participation\n\nExclusion Criteria:\n\n* pregnant women\n* people with cardio-pulmonary and musculoskeletal diseases or any other impairment that would risk harm for the volunteer while performing CPR\n* physical and\u002For psychological disabilities\n* technical issue during data collection",true,"ALL","16 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","Out-of-hospital cardiac arrest (OHCA) remains a leading cause of mortality worldwide, with survival highly dependent on the immediate initiation of bystander cardiopulmonary resuscitation (CPR). Early recognition, prompt chest compressions, and rapid defibrillation are critical components of the chain of survival. Telephone-assisted CPR (T-CPR) provided by emergency dispatchers has been shown to significantly increase bystander intervention rates and improve outcomes. While the availability and use of automated external defibrillators (AEDs) further enhance survival, the optimal integration of AED use into dispatcher-guided, single-rescuer scenarios remains insufficiently studied.\n\nThis prospective, randomized, controlled simulation study aims to evaluate the effect of modified telephone cardiopulmonary resuscitation (T-CPR) instructions optimized for automated external defibrillator (AED) use on no-flow time and chest compression fraction (CCF) during single-rescuer resuscitation. Participants are randomized to receive either standard T-CPR instructions or enhanced instructions focusing on minimizing interruptions in chest compressions and reducing time to first compression during AED use.",[27],"Cardiac Arrest (CA)",[29,30,31,32,33],"cardiac arrest","automated external defibrillator","dispatcher-assisted cardiopulmonary resuscitation","no-flow time","chest compression fraction","RECRUITING","2026-07-09",{"date":37,"type":38},"2026-07-13","ACTUAL",{"date":40,"type":38},"2026-07-10",{"date":42,"type":21},"2026-09-30",{"name":44,"class":45},"University of Pecs","OTHER",1,{"id":48,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":50,"briefSummary":25,"conditions":51,"keywords":52,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":46},"100632991",{"count":20,"type":21},[24],[27],[29,30,31,32,33],"2026-04-08",{"date":55,"type":38},"2026-04-14",{"date":57,"type":21},"2026-05-01",{"date":59,"type":21},"2026-08-31",{"name":44,"class":45},{"id":62,"slug":63,"hasResults":11,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":4,"eligibilityCriteria":67,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":4,"studyType":22,"phases":72,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":46},"100596343","the-effect-of-chlorhexidine--hyaluronic-acid-on-postoperative-wound-healing-after-lower-third-molar-removal-100596343","NCT07044219","The Effect of Chlorhexidine + Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal","The Effect of Chlorhexidine (0.5%) With Combination of Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal: a Placebo Controlled Triple Blind Randomized Clinical Trial","Inclusion Criteria:\n\n* patients having lower impacted third molar\n* impaction pattern Pell-Gregory II\u002FA, III\u002FA, I\u002FB, II\u002FB, III\u002FB that means partially impacted, partially erupted teeth, where primary wound closure is usually not possible;\n\nExclusion Criteria:\n\n* systemic disease (diabetes, steroids, antiresorptive therapy);\n* allergy on gel's compounds;\n* pregnancy;\n* active or subacute local infection at third molar tooth (pericoronitis);\n* poor oral hygiene (based on the presence of active caries and\u002For plaque index of 2-3)","18 Years","99 Years",{"count":71,"type":21},60,[24],"Our aim is to evaluate chlorhexidine-hyaluronic acid containing gel on postoperative wound healing regarding impacted lower third molar surgery.",[75,76],"Dry Socket","Postoperative Infections",[78,79,80],"alveolitis","dry socket","dehiscence","NOT_YET_RECRUITING","2025-06-27",{"date":84,"type":38},"2025-06-29",{"date":86,"type":21},"2025-07-01",{"date":88,"type":21},"2026-08-01",{"name":44,"class":45},{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":96,"eligibilityCriteria":97,"healthyVolunteers":11,"sex":17,"minAge":98,"maxAge":4,"enrollmentInfo":99,"targetDuration":4,"studyType":22,"phases":101,"briefSummary":103,"conditions":104,"keywords":107,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":46},"100443924","phase-4-iron-supplementation-in-upper-non-variceal-gastrointestinal-bleeding-100443924","NCT05060731","Iron Supplementation in Upper Non-variceal Gastrointestinal Bleeding","Intravenous Ferric Carboxymaltose Versus Oral Ferrous Sulfate Replacement in Anaemia Due to Acute Nonvariceal Gastrointestinal Bleeding (FIERCE): Protocol of a Multicentre Randomised Controlled Trial","FIERCE","Inclusion Criteria:\n\n1. age ≥ 65 years;\n2. endoscopically proven acute nonvariceal GIB source;\n3. 48 hours after the endoscopic diagnosis and\u002For treatment;\n4. hemodynamically stable;\n5. the discharge of the patient is planned;\n6. hemoglobin level \\\u003C10 g\u002Fdl on the day of randomisation;\n7. 24 hours after the last transfusion and no need for further transfusion;\n8. signed informed consent.\n\nExclusion Criteria:\n\n1. known hypersensitivity to iron products (mild side effects excluded);\n2. previous diagnosis of iron overload \\[e.g., transferrin receptor saturation (TSAT) \\>50%, ferritin\\> 160 for women ng\u002Fml, ferritin \\>270 ng\u002Fml for men) or disorders of iron utilisation;\n3. pregnancy or breast feeding;\n4. diagnosis of iron malabsorption (at discretion of the attending clinician; e.g., severe inflammatory bowel disease, active celiac disease);\n5. chronic end stage diseases (chronic heart failure-New York Heart Association Classification class 4, chronic kidney disease (eGFR \\\u003C30 mL\u002Fmin\u002F1.73 m2) with or without dialysis, liver cirrhosis with Child Pugh C score, chronic kidney disease with dialysis, chronic obstructive pulmonary disease stage 4, chronic inflammatory disease, malignancies, AIDS);\n6. active malignancies;\n7. liver cirrhosis with known varices at high risk of bleeding - endoscopic features of high risk of variceal bleeding or liver stiffness measured by transient elastography \\>20 kiloPascal and platelet count \\\u003C150 × 10\\^9 cells\u002FL;\n8. gastrointestinal tract malignancies with high risk of gastrointestinal bleeding;\n9. high risk of poor compliance or no fixed abode;\n10. myelo- or lymphoproliferative diseases;\n11. anemia not attributable to iron deficiency (sideroblastic anaemia, aplastic anaemia, haemolytic anaemia, thalassaemia, B12 vitamin or folic acid deficiency or combination of these with IDA);\n12. primary coagulation disorders (e.g. Glanzmann thrombasthenia, Von Willebrand disease, Haemophylia A, Haemophylia B);\n13. the patient will be transferred to another institute after discharge (e.g. hospital, senior care center);\n14. Eastern Cooperative Oncology Group (ECOG) Performance Status \\>2.","65 Years",{"count":100,"type":21},570,[102],"PHASE4","Anemia is a frequent complication of gastrointestinal bleeding, affecting 61% of the patients. Currently, anemia caused by gastrointestinal bleeding can be treated with iron supplementation. However, the dose and route of the administration are still a question. The FIERCE clinical trial aims to compare the effect of intravenous iron supplementation and oral iron replacement on mortality, unplanned emergency visits, and hospital readmissions in multimorbid patients with acute nonvariceal gastrointestinal bleeding.",[105,106],"GastroIntestinal Bleeding","Anemia",[108,109,110],"non-variceal upper gastrointersinal bleeding","iron supplementation","intravenous iron","2025-03-25",{"date":113,"type":38},"2025-03-30",{"date":115,"type":21},"2025-09-01",{"date":117,"type":21},"2028-02-01",{"name":44,"class":45},{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":4,"eligibilityCriteria":125,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":126,"enrollmentInfo":127,"targetDuration":4,"studyType":129,"phases":4,"briefSummary":130,"conditions":131,"keywords":138,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":154},"100577805","investigation-of-the-mechanisms-of-the-tendency-to-hypothermia-in-newborns-and-premature-neonates-100577805","NCT06803069","Investigation of the Mechanisms of the Tendency to Hypothermia in Newborns and Premature Neonates","Investigation of the Mechanisms of the Tendency to Hypothermia in Newborns and Premature Infants During Surgical Interventions and in the Intensive Care Unit (Non-Interventional, Single-Center, Prospective Clinical Research)","Inclusion Criteria:\n\n* For Substudy 1: Patients admitted to the Neonatal Intensive Care Unit at the University of Pécs, Department of Obstetrics and Gynaecology (premature infants or those in neonatal intensive care).\n* For Substudy 2: Patients under 2 years of age undergoing elective surgery lasting more than 30 minutes at the University of Pécs, Department of Paediatrics.\n* For both substudies: Written consent for participation in the study has been provided by the patient's parent, guardian, or legal representative.\n\nExclusion Criteria:\n\n* For both substudies: If the patient cannot be mobilized (e.g., during the post-operative phase of abdominal or thoracic surgery; presence of chest tubes for pneumothorax or other reasons; hemodynamic instability; need for continuous electrocardiogram (ECG) monitoring; or use of an external pacemaker).\n* The patient's parent, guardian, or legal representative does not consent to the study or withdraws their consent at any point.\n* For Substudy 2: if the patient is older than 2 years.","2 Years",{"count":128,"type":21},100,"OBSERVATIONAL","Newborns have thermoregulatory mechanisms that differ from those of adults. Instead of producing heat through shivering, newborns primarily rely on non-shivering thermogenesis by the brown adipose tissue. The development of this thermogenic tissue starts around the 26th gestational week and continues until shortly before birth, after which no further growth occurs. As a result, premature infants, who have less developed brown fat, are more prone to reduced heat production and are at higher risk for hypothermia. There are few human studies examining the thermoregulatory differences and mechanisms between full-term and premature neonates, and the findings remain inconclusive.\n\nIn this study, the investigators aim to conduct a prospective, observational research. Researchers will compare body temperature, brown adipose tissue activity, and specific plasma markers between full-term and premature neonates in insensive care units and during elective surgeries.",[132,133,134,135,136,137],"Neonatal Hypothermia","Brown Adipose Tissue","Preterm and Term Infants","Neonate","Thermogenesis","Blood Markers",[139,140,141,142,143,144,145],"brown adipose tissue","neonate","neonatal hypothermia","preterm","nonshivering thermogenesis","infant","newborn","2025-02-18",{"date":148,"type":38},"2025-02-19",{"date":150,"type":38},"2024-07-01",{"date":152,"type":21},"2029-07-01",{"name":44,"class":45},2,{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":161,"eligibilityCriteria":162,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":163,"enrollmentInfo":164,"targetDuration":4,"studyType":129,"phases":4,"briefSummary":166,"conditions":167,"keywords":169,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":4},"100577228","complex-fertility-awareness-study---hungary-100577228","NCT06795568","Complex Fertility Awareness Study - Hungary","Examination of Fertility Awareness with an Integrative Approach: a Mixed-method Multi-centre Research Study","FAIR-HU","Inclusion Criteria:\n\n* Inclusion criteria will be BMI ≥ 18 kg\u002Fm2 and ≤ 38 kg\u002Fm2, 18 to 45 years of age, having undergone not more than three unsuccessful cycles and no significant health risk relevant to the ART procedure and outcome (metabolic and vascular diseases including diabetes mellitus, metabolic syndrome, fatty liver diseases and atherosclerosis\n\nExclusion Criteria:\n\n* Participants diagnosed with any mental disorders and significant physical or mobility impairments will be excluded.","45 Years",{"count":165,"type":21},750,"The goal of this observational study is to investigate integrative fertility awareness and its impact on assisted reproductive techniques (ART) in Hungary. It analyzes fertility awareness, health-movement behavior, physical literacy, dietary patterns, psycho-social distress, socio-demographic parameters, and stress biomarkers across four fertility centers. The study employs a mixed-method approach. The research aims to review and analyze the factors of integrative fertility awareness on the course and outcome measures of assisted reproductive techniques (ART) at different fertility centers in Hungary in a mixed-method study.",[168],"Infertility, Sterility, Reproductive, Reproductive Sterility, Sterility, Subfertility, Sub-Fertility",[170],"Fertility; integrative approach; infertility; assisted reproductive techniques, IVF; health behaviour; physical activity; dietary","2025-01-21",{"date":173,"type":38},"2025-01-28",{"date":175,"type":21},"2025-02-15",{"date":177,"type":21},"2026-12-31",{"name":44,"class":45},{"id":180,"slug":181,"hasResults":11,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":185,"eligibilityCriteria":186,"healthyVolunteers":11,"sex":17,"minAge":68,"maxAge":187,"enrollmentInfo":188,"targetDuration":4,"studyType":129,"phases":4,"briefSummary":190,"conditions":191,"keywords":197,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":209,"locationsCount":154},"100559285","multidimensional-examination-of-patients-with-colorectal-and-anal-cancer-100559285","NCT06562140","Multidimensional Examination of Patients with Colorectal and Anal Cancer","Multidimensional Examination of Physical Activity, Functional Capacity, and Health Status in Patients with Colorectal and Anal Cancer","MECACP","Inclusion Criteria:\n\n* adult (18-80 years) patients with a diagnosis of colorectal or anal carcinoma\n\nExclusion Criteria:\n\n* Neuromuscular diseases\n* severe congenital musculoskeletal and other disorders,\n* severe psychiatric illness, lack of cooperation,\n* undergone other surgical procedures within the past year.","80 Years",{"count":189,"type":21},300,"The aim of our cross-sectional research is to assess changes in physical activity, functional capacity, and health status in individuals with colorectal and anal carcinoma using subjective measurement tools, with particular focus on those suffering from incontinence, through a cross-sectional study. Additionally, the research involves the Hungarian adaptation and validation of the quality of life questionnaire for colorectal cancer (EORTC QLQ-CR29), quality of life questionnaire for anal cancer (EORTC QLQ-AN27), and Fecal Incontinence Severity Index (FISI)\" questionnaires.",[192,193,194,195,196],"Colorectal Cancer","Anal Cancer","Physical Inactivity","Fecal Incontinence","Quality of Life",[198,199,200,201,202],"colorectal cancer","anal cancer","quality of life","physical activity","fecal incontinence","2025-01-20",{"date":205,"type":38},"2025-01-23",{"date":207,"type":38},"2024-08-15",{"date":115,"type":21},{"name":44,"class":45},{"id":211,"slug":212,"hasResults":11,"nctId":213,"briefTitle":214,"officialTitle":214,"acronym":215,"eligibilityCriteria":216,"healthyVolunteers":11,"sex":17,"minAge":68,"maxAge":4,"enrollmentInfo":217,"targetDuration":4,"studyType":22,"phases":219,"briefSummary":220,"conditions":221,"keywords":223,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":228,"lastUpdatePostDateStruct":229,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":235,"locationsCount":46},"100479983","cardiovascular-risk-factors-in-coeliac-disease-a-series-of-studies-100479983","NCT05530070","Cardiovascular Risk Factors in Coeliac Disease: a Series of Studies","ARCTIC","Inclusion Criteria (applies to all subjects):\n\n* Age should be over 18 years.\n* Blood collection must be indicated with medical conditions.\n* Signed informed consent.\n\nInclusion Criteria (applies to specific cohorts of patients):\n\n* The diagnosis of CD should be set up according to the current guidelines (based on serology and histology in adults or as per the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) guideline in children).\n* The newly diagnosed CD patients should be on a gluten-containing diet.\n* Patients following a GFD for at least 1 year should exhibit good dietary adherence.\n* In the randomized controlled trial (RCT), strict dietary adherence will be established based on CD-specific serology (normal level of antibodies), urine gluten immunogenic peptides (negative urine test), and dietary interview (convincing knowledge on the GFD and positive attitude towards strict adherence). Adherence to the mediterranean diet should be suboptimal (≤ 8 Medietrranean Diet Score). RCT-patients must have internet access and must be capable to attend the online sessions for 1 year.\n* Control subjects should be free from CD according to the recent guidelines and should be on a gluten-containing diet.\n\nExclusion Criteria:\n\n* Chronic conditions:\n\n  * Estimated glomerular filtration rate calculated with the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula is \\\u003C60mL\u002Fmin\u002F1.73m2 (CKD3 or more severe kidney failure).\n  * Liver cirrhosis in Child-Pugh class B-C.\n  * Heart failure (New York Heart Association (NYHA) III-IV).\n  * Active malignant diseases.\n* Any acute diseases or acute deterioration of underlying chronic conditions.\n* Diseases that may be associated with clinically relevant malabsorption.\n* Refractory CD.\n* Pregnancy, lactation.\n* Patients unable to understand the essentials of the informed consent.\n* Lack of consent or withdrawal of consent.",{"count":218,"type":21},190,[24],"This investigation examines the most important cardiovascular risk factors (e.g., metabolic parameters, body composition) and their changes in coeliac disease. The series of studies allow to assess body composition and cardiovascular risk-related metabolic parameters of newly diagnosed and treated coeliac patients in their complexity and to test if they change during therapy. The interventional part of the investigation aims to answer the question if a dietary intervention mitigates the unfavorable effects of unbalanced diet.",[222],"Coeliac Disease",[224,225,226,227],"coeliac disease","cardiovascular risk","body composition","dietary intervention","2025-01-18",{"date":230,"type":38},"2025-01-22",{"date":232,"type":38},"2022-09-01",{"date":234,"type":21},"2026-12",{"name":44,"class":45},{"id":237,"slug":238,"hasResults":11,"nctId":239,"briefTitle":240,"officialTitle":241,"acronym":4,"eligibilityCriteria":242,"healthyVolunteers":11,"sex":243,"minAge":68,"maxAge":187,"enrollmentInfo":244,"targetDuration":4,"studyType":129,"phases":4,"briefSummary":245,"conditions":246,"keywords":249,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":253,"startDateStruct":255,"completionDateStruct":257,"leadSponsor":259,"locationsCount":154},"100572249","body-image-and-physical-activity-of-women-with-breast-cancer-100572249","NCT06730815","Body Image and Physical Activity of Women with Breast Cancer","Body Image and Physical Activity of Women with Breast Cancer Self-developed Questionnaire-based Follow-up Clinical Trial","Inclusion Criteria:\n\n* Adult women diagnosis of breast carcinoma\n\nExclusion Criteria:\n\n* neuromuscular diseases\n* severe congenital musculoskeletal and other disorders\n* other surgical procedures within 1 year","FEMALE",{"count":189,"type":21},"The goal of this self-initiated questionnaire-based follow-up clinical trial is to map the body image and physical activity of Hungarian women treated for breast cancer.\n\nThe main questions it aims to answer are:\n\n1. How body image changes during different treatments among women treated for breast cancer?\n2. How is physical activity among Hungarian women treated for breast cancer?",[247,194,196,248],"Breast Cancer Female","Body Image",[250,201,251],"body image after breast cancer","life quality","2024-12-16",{"date":254,"type":38},"2024-12-19",{"date":256,"type":38},"2024-09-01",{"date":258,"type":21},"2025-08-31",{"name":44,"class":45},{"id":261,"slug":262,"hasResults":11,"nctId":263,"briefTitle":264,"officialTitle":264,"acronym":265,"eligibilityCriteria":266,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":267,"enrollmentInfo":268,"targetDuration":4,"studyType":22,"phases":270,"briefSummary":271,"conditions":272,"keywords":275,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":288,"locationsCount":46},"100566932","effect-of-practicing-yoga-and-meditation-on-cortisol-hormone-immunoglobulin-a-and-metabolic-parameter-among-medical-students-100566932","NCT06661603","Effect of Practicing Yoga and Meditation on Cortisol Hormone, Immunoglobulin A and Metabolic Parameter Among Medical Students","GSY","Inclusion Criteria:\n\nThe inclusion criteria for the study required participants to be currently enrolled in the Medicine Faculty of the University of Pecs\n\nExclusion Criteria:\n\nStudents with illnesses (such as recent injuries, chronic pain, or significant arthritis) that would make it unsafe for them to take part in a yoga intervention will be excluded from the study.","40 Years",{"count":269,"type":21},280,[24],"This clinical trial aims to develop and test a yoga intervention to improve cortisol hormone rhythm, immunoglobulin A, and metabolic markers among medical students. The development of the yoga protocol, \"GSY Goodbye Stress with Yoga Proto-col,\" was a collaborative effort involving a certified yoga trainer, medical researcher, and experienced yogis from India. GSY yoga intervention, which includes yoga asanas poses, breathing techniques, and guided meditation, may reduce stress levels, improve immunity, and enhance other metabolic parameters in medical students.",[273,274],"Healthy","Adult Children",[276,277,278,279,280],"Medical students","Yoga","Cortisol Hormone","Immunoglobulin","mental health","2024-12-04",{"date":283,"type":38},"2024-12-09",{"date":285,"type":38},"2022-02-07",{"date":287,"type":21},"2025-07",{"name":44,"class":45},{"id":290,"slug":291,"hasResults":11,"nctId":292,"briefTitle":293,"officialTitle":294,"acronym":4,"eligibilityCriteria":295,"healthyVolunteers":11,"sex":17,"minAge":296,"maxAge":187,"enrollmentInfo":297,"targetDuration":4,"studyType":22,"phases":299,"briefSummary":300,"conditions":301,"keywords":303,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":308,"lastUpdatePostDateStruct":309,"startDateStruct":311,"completionDateStruct":313,"leadSponsor":315,"locationsCount":46},"100548729","therapeutic-effect-of-the-natural-mineral-water-of-the-well-b-308-okk-in-gyr-gyirmt-on-knee-osteoarthrosis-100548729","NCT06424782","Therapeutic Effect of the Natural Mineral Water of the Well B-308 OKK in Győr (Gyirmót) on Knee Osteoarthrosis","Investigation of the Therapeutic Effect of the Natural Mineral Water of the Well B-308 OKK in Győr (Gyirmót) Among People With Knee Arthrosis (Randomized, Controlled, Double-blind, Follow-up Study)","Inclusion Criteria:\n\n* Knee osteoarthrosis that has existed for at least 3 months\n* Age between 50 and 80 years\n* Willingness to participate in 3-week outpatient rehabilitation treatment\n* Pain in the knee joint lasting at least 3 months and at least 5 days a week\n* At least mild pain during selection (1 point on the Likert scale)\n* Does not have a serious disability\n\nExclusion Criteria:\n\n* Any kind of physiotherapy treatment in the last 2 months (except home gymnastics)\n* Any previous knee joint surgery\n* Any trauma to the knee or hip joint in the 1 year prior to the examination\n* Knee arthroscopy performed within 3 months prior to the examination\n* Intra-articular corticosteroid treatment of the affected knee in the last 3 months\n* Palpable Baker's cyst\n* Any hip joint or spine surgery within a year before the examination\n* Intra-articular hyaluronic injection within 2 months before the examination\n* Appearance of lumbar radiculopathy\n* Presence of serious internal medicine disease, urogenital or other diseases\n* Uncooperative or psychoneurotic patients\n* Lumbago, sciatica; and any other surgery or previous fracture in the hip joint\n* Subluxation, luxation, algodystrophy, fibromyalgia, gout\n* Balneotherapy in the last 6 months\n* Systemic corticosteroid treatment in 1 month before the examination\n* Starting the treatment of osteoarthritis SYSADOA (symptomatic slow-acting drugs for osteoarthritis) in 3 months before the examination","50 Years",{"count":298,"type":21},50,[24],"The main purpose of the study is to investigate the therapeutic effect of the thermal water of Győr (Gyirmót) well No. B-308 OKK on patients with knee arthrosis, and to compare its therapeutic effect with tap water (placebo) group.",[302],"Knee Osteoarthritis",[304,305,306,307],"medicinal water","healing water","balneotherapy","WOMAC","2024-05-16",{"date":310,"type":38},"2024-05-22",{"date":312,"type":21},"2024-09",{"date":314,"type":21},"2026-09",{"name":44,"class":45},{"id":317,"slug":318,"hasResults":11,"nctId":319,"briefTitle":320,"officialTitle":321,"acronym":4,"eligibilityCriteria":322,"healthyVolunteers":16,"sex":243,"minAge":68,"maxAge":296,"enrollmentInfo":323,"targetDuration":4,"studyType":129,"phases":4,"briefSummary":325,"conditions":326,"keywords":328,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":331,"lastUpdatePostDateStruct":332,"startDateStruct":334,"completionDateStruct":336,"leadSponsor":338,"locationsCount":46},"100548609","anal-incontinence-and-its-impact-on-quality-of-life-and-physical-activity-among-hungarian-women-and-the-hungarian-language-validation-of-the-international-consultation-on-incontinence-modular-questionnaire-bowels-iciq-b-100548609","NCT06423222","Anal Incontinence and Its Impact on Quality of Life and Physical Activity Among Hungarian Women and the Hungarian Language Validation of the International Consultation on Incontinence Modular Questionnaire-Bowels (ICIQ-B)","Prevalence of Anal Incontinence and Its Impact on Quality of Life and Physical Activity Among Hungarian Women Who Have Given Birth, and the Hungarian Language Validation of the International Consultation on Incontinence Modular Questionnaire-Bowels (ICIQ-B)","Inclusion Criteria:\n\n* Have given birth at least once before\n* Native Hungarian language\n\nExclusion Criteria:\n\n* Menopause\n* Irritable Bowel Syndrome (IBS)\n* Chron's disease\n* Ulcerative colitis\n* Developmental abnormalities at the level of the pelvic organs\n* Uninvestigated pelvic pain\n* Malignant pelvic tumor\n* Radiotherapy involving the pelvis\n* Neurological diseases with muscle weakness\n* Parkinson's disease\n* Intellectual disability",{"count":324,"type":21},250,"The aim of the study is to assess the prevalence of anal incontinence among Hungarian women who have given birth at least once before, and to examine the impact of anal incontinence on the quality of life and physical activity of these women. A further aim of our study is to adapt the Hungarian version of the International Consultation on Incontinence Modular Questionnaire - Bowels (ICIQ-B) and to assess its validity and reliability.",[327],"Anal Incontinence",[327,196,329,330],"Physical Activity","Questionnaire","2024-05-15",{"date":333,"type":38},"2024-05-21",{"date":335,"type":38},"2024-04-22",{"date":337,"type":21},"2027-07",{"name":44,"class":45},{"id":340,"slug":341,"hasResults":11,"nctId":342,"briefTitle":343,"officialTitle":344,"acronym":345,"eligibilityCriteria":346,"healthyVolunteers":11,"sex":17,"minAge":68,"maxAge":187,"enrollmentInfo":347,"targetDuration":4,"studyType":22,"phases":349,"briefSummary":350,"conditions":351,"keywords":354,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":360,"lastUpdatePostDateStruct":361,"startDateStruct":363,"completionDateStruct":365,"leadSponsor":367,"locationsCount":46},"100412172","preventing-the-recurrence-of-acute-pancreatitis-by-alcohol-and-smoking-cessation-100412172","NCT04647097","Preventing the Recurrence of Acute Pancreatitis by Alcohol and Smoking Cessation","Recurrent Acute Pancreatitis Prevention by the Elimination of Alcohol and Cigarette Smoking (REAPPEAR): Protocol of a Randomized Controlled Trial and a Cohort Study","REAPPEAR","Inclusion criteria:\n\n* Patient hospitalized with alcohol-induced AP (defined by the revised Atlanta criteria 38)\n* Every day smoker (defined as an adult patient who smoked at least 100 cigarettes in his or her lifetime, and now smokes on a daily basis; as per the CDC definition), with at least 1-year history of smoking\n* Aged 18-80 years\n* Provided written informed consent\n* Willing to participate in the intervention in every three months\n\nExclusion criteria:\n\n* Possible etiologies for AP other than alcohol (eg. gallstone-related, hypertriglyceridemia above 11.5 mM 40-42, hypercalcemia, viral infection) if the etiological cannot be terminated during the index admission (lack of same admission cholecystectomy, familiar hypertrygliceridemia) and cases with combined etiological factors will be excluded\n* Untreated, decompensated or severe mMajor psychiatric illnesses (e.g. schizophrenia, bipolar disorder, dementia)\n* Currently taking part in a smoking cessation program\n* Undergoing active or palliative treatment for malignancy\n* Pregnancy, breastfeeding\n* Life expectancy is less than two years\n* Didn't agreed to participate\n* Other",{"count":348,"type":21},364,[24],"Recurrence of acute pancreatitis (AP) is often facilitated by regular alcohol consumption and smoking. An applied lifestyle intervention focusing on the cessation of alcohol consumption and smoking might prevent the recurrence of AP. REAPPEAR Study is a randomized controlled trial and a cohort study focusing on the efficacy of the lifestyle intervention and the effect of quitting alcohol and smoking respectively.",[352,353],"Acute Pancreatitis","Recurrent Acute Pancreatitis",[355,356,357,358,359],"acute pancreatitis","recurrent acute pancreatitis","smoking","alcohol","lifestyle intervention","2023-04-25",{"date":362,"type":38},"2023-04-26",{"date":364,"type":38},"2022-03-01",{"date":366,"type":21},"2028-06-30",{"name":44,"class":45},{"id":369,"slug":370,"hasResults":11,"nctId":371,"briefTitle":372,"officialTitle":373,"acronym":374,"eligibilityCriteria":375,"healthyVolunteers":11,"sex":17,"minAge":376,"maxAge":4,"enrollmentInfo":377,"targetDuration":4,"studyType":22,"phases":379,"briefSummary":380,"conditions":381,"keywords":382,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":386,"lastUpdatePostDateStruct":387,"startDateStruct":389,"completionDateStruct":391,"leadSponsor":392,"locationsCount":46},"100420958","the-effect-of-dietary-fat-content-on-the-recurrence-of-pancreatitis-100420958","NCT04761523","The Effect of Dietary Fat Content on the Recurrence of Pancreatitis","The Effect of Dietary Fat Content on the Recurrence of Pancreatitis (EFFORT): Protocol of a Multicentre Randomized Controlled Trial","EFFORT","Inclusion Criteria:\n\n* Individuals with at least two episodes of acute pancreatitis in the 2 years preceding the inclusion with\n* The last episode being idiopathic, who are\n* Older than 14 years.\n\nExclusion Criteria:\n\n* Individuals already receiving regular nutritional guidance (with medical indication),\n* Individuals in critical condition or in terminal stage of cancer (with an expected survival \\\u003C2 years) ,\n* Individuals undergoing treatment for active malignancy,\n* Individuals with uncontrolled diabetes mellitus (admitted lack of compliance with antidiabetic therapy \u002F HbA1c \\>6.5% \u002F indication of uncontrolled diabetes mellitus in last 24 months' anamnesis \u002F newly discovered diabetes mellitus)\n* Individuals with known cholecystolithiasis\n* Individuals who are pregnant or nursing\n* Individuals with a BMI \\\u003C 18.5\n* Individuals who are regularly receiving systemic corticosteroids\n* Individuals consuming more alcohol than: 5 units per day or 15 units per week for men; 4 units per day or 8 units per week for women.","14 Years",{"count":378,"type":21},384,[24],"This trial aims to test the effects of two different diets on the recurrence of acute pancreatitis, and acute pancreatitis associated mortality.",[352],[355,383,384,385],"dietary fat","low-fat diet","pancreatitis recurrence","2022-11-14",{"date":388,"type":38},"2022-11-15",{"date":390,"type":38},"2022-05-01",{"date":177,"type":21},{"name":44,"class":45},{"id":394,"slug":395,"hasResults":11,"nctId":396,"briefTitle":397,"officialTitle":398,"acronym":4,"eligibilityCriteria":399,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":400,"targetDuration":4,"studyType":129,"phases":4,"briefSummary":401,"conditions":402,"keywords":404,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":406,"lastUpdatePostDateStruct":407,"startDateStruct":409,"completionDateStruct":411,"leadSponsor":413,"locationsCount":46},"100463806","the-clinical-epidemiological-and-treatment-characteristics-of-head-and-neck-cancer-patients-100463806","NCT05319483","The Clinical, Epidemiological and Treatment Characteristics of Head and Neck Cancer Patients","The Clinical, Epidemiological and Treatment Characteristics of Head and Neck Cancer Patients Presenting to Different Levels of the Health Care System","Inclusion Criteria:\n\n* Patients 18 years or over presenting with head and neck cancer (with morphology of squamocellular carcinoma), who are subsequently given one of the following ICD-10 codes: Malignant neoplasms of lip, oral cavity and pharynx (C00-C14), Malignant neoplasm of larynx (C32) and for whom this is their first cancer.\n\nExclusion Criteria:\n\n* Patients who do not meet the inclusion criteria and patients who meet the inclusion criteria but for whom this is a second or recurrent cancer (they already have an \"ICD-C\" code) are excluded from the study",{"count":128,"type":21},"The aim of our study is to prospectively collect information regarding (1) the demographic, lifestyle-related and clinical characteristics of patients with head and neck cancer and (2) the waiting times to diagnosis and therapy, and the 1-, 3- and 5-year survival of patients. We plan to gain insight into the characteristics and pathways of head and neck cancer patients in Baranya County, which can in turn help to identify factors that lead to improved or worse disease outcomes. (Thus, these factors can subsequently eliminated or lessened to improve the outcome of head and neck cancer patients. )",[403],"Waiting Times, Patient Pathways, Effect of Lifestyle-related, Clinical and Demographic Parameters on Outcomes",[405],"Head and neck cancer, Survival, Waiting times, Patient pathways","2022-03-31",{"date":408,"type":38},"2022-04-08",{"date":410,"type":38},"2021-10-01",{"date":412,"type":21},"2029-10-01",{"name":44,"class":45},{"id":415,"slug":416,"hasResults":11,"nctId":417,"briefTitle":418,"officialTitle":419,"acronym":420,"eligibilityCriteria":421,"healthyVolunteers":11,"sex":17,"minAge":68,"maxAge":187,"enrollmentInfo":422,"targetDuration":4,"studyType":22,"phases":424,"briefSummary":425,"conditions":426,"keywords":430,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":438,"lastUpdatePostDateStruct":439,"startDateStruct":441,"completionDateStruct":443,"leadSponsor":444,"locationsCount":46},"100446998","the-role-of-irritable-bowel-syndrome-in-lactose-intolerance-lion-100446998","NCT05100719","The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION)","The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION Trial): Protocol of a Multicentre Randomized Controlled Clinical Trial","LION","Inclusion Criteria:\n\n* age 18-80 years\n* patients diagnosed with irritable bowel syndrome based on the ROME IV. criteria\n* positive LHBT (lactose H2 breath test) and LTT (lactose tolerance test) results\n* negative abdominal ultrasound\u002FCAT scan\u002FMRI results within one year\n* signed the informed consent\n\nExclusion Criteria:\n\n* organic gastroenterological disorders which can explain symptoms (e.g. positive serological screening: anti-gliadin IgG \u002F IgA, anti-tissue transglutaminase IgG \u002F IgA, high level of fecal calprotectin tested by endoscopy or positive colonoscopy for IBD, currently active diverticulitis\n* Alarm symptoms: fever (\\> 38 Co), anaemia (Hgb \\\u003C 120 g\u002Fl), unintended weight loss (\\> 4.5 kg \u002F 3 months), gastrointestinal bleeding (hematemesis, hematochesia, melena)\n* cardiac failure (NYHA III-IV)\n* liver cirrhosis (Child-Pugh C)\n* active malignancy\n* major abdominal surgery in the history\n* pregnant or breastfeeding women\n* any circumstances which can lead to false results of LHBT and LTT: cigarette smoking or physical exercise within 2 hours before the test, ingestion of dietary fibers on the evening before the test, recent use of antibiotics, lung disease, baseline H2 concentration in the exhaled air is higher than 20 ppm, not properly treated diabetes mellitus, following lactose restricted or another special diet within 1 week prior to study enrolment (ingestion of less than 12 g lactose - less than 250 ml milk - per day)\n* small intestinal bacterial overgrowth (SIBO): if there is a rapid increase of H2 level in the exhaled air (≥20 ppm above baseline within 90 minutes), SIBO is suspected and antibiotic therapy will be started (peroral rifaximin for 5 days) after negative Helicobacter pylori serology. After this procedure, lactulose H2 breath test will be performed to exclude SIBO (≥20 ppm H2 rise only after 90 min). In case of negative lactulose H2 breath test, another LHBT will be carried out\n* slow oro-cecal transit: clinical signs and typical findings on the tests (the LHBT is normal, but the increase of blood glucose level is less than 1.1 mmol\u002Fl and\u002For no H2 rise during lactulose H2 breath test)\n* milk allergy (positive IgE test)",{"count":423,"type":21},200,[24],"Irritable bowel syndrome (IBS) is a functional gastrointestinal disease. There is no well-defined pharmacological treatment. This clinical trial is a prospective, double-blind, two-armed randomized controlled, single-center trial. It is created to examine the role of IBS in patients with lactose intolerance. IBS patients undergo lactose H2 breath test (LHBT) and lactose tolerance test (LTT). Those with positive LTT and LHBT will be randomized into two groups: alverine-citrate + simethicone and lactase group (1) or alverin-citrate + simethicone with the placebo group (2). The goal of this study is to compare the lactase enzyme with placebo in IBS patients with lactose intolerance.",[427,428,429],"Irritable Bowel Syndrome","Lactose Intolerance","Lactose Malabsorption",[431,432,433,434,435,436,437],"irritable bowel syndrome","lactose intolerance","lactose malabsorption","lactase","simethicone","alverine-citrate","placebo","2021-10-19",{"date":440,"type":38},"2021-10-29",{"date":442,"type":21},"2022-09",{"date":234,"type":21},{"name":44,"class":45},{"id":446,"slug":447,"hasResults":11,"nctId":448,"briefTitle":449,"officialTitle":450,"acronym":451,"eligibilityCriteria":452,"healthyVolunteers":11,"sex":17,"minAge":68,"maxAge":4,"enrollmentInfo":453,"targetDuration":4,"studyType":129,"phases":4,"briefSummary":455,"conditions":456,"keywords":458,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":462,"lastUpdatePostDateStruct":463,"startDateStruct":465,"completionDateStruct":467,"leadSponsor":468,"locationsCount":4},"100427537","preoperative-biliary-drainage-in-malignant-biliary-obstruction-100427537","NCT04847297","Preoperative Biliary Drainage in Malignant Biliary Obstruction","Preoperative Biliary Drainage in Malignant Biliary Obstruction - an Observational Cohort Study","PEAR","Inclusion Criteria:\n\n1. Patients ≥ 18 years\n2. OJ of malignant origin (pancreatic head or periampullary tumor)\n3. Total bilirubin level ≥ 40 μmol per liter\n4. Signed written informed consent\n\nExclusion Criteria:\n\n1. Proved metastasis\n2. Irresectable tumor\n3. Neo-adjuvant chemotherapy\n4. Co-existing malignancy\n5. Pregnancy\n6. Patients not fit for resection",{"count":454,"type":21},353,"The first alarming symptom of a malignancy of the pancreas or periampullary tumor can be obstructive jaundice (OJ). Pancreato-duodenectomy (PD) combined with oncological treatment can provide long disease-free survival in resectable cases. The literature regarding the preoperative biliary drainage is controversial. The aim of this multicenter, prospective observational cohort study is to investigate the role of preoperative drainage, and to compare it with surgery alone.",[457],"Pancreatic Cancer",[459,460,461],"pancreatic cancer","biliary drainage","pancreato-duodenectomy","2021-04-14",{"date":464,"type":38},"2021-04-19",{"date":466,"type":21},"2021-09-01",{"date":177,"type":21},{"name":44,"class":45},""]