[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Regina\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":436},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,17,0,[8,45,75,98,124,143,165,183,207,230,251,274,309,336,364,386,407],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100372256","internet-delivered-cognitive-behaviour-therapy-for-public-safety-personnel-100372256",false,"NCT04127032","Internet-Delivered Cognitive Behaviour Therapy for Public Safety Personnel","Internet-Delivered Cognitive Behaviour Therapy (ICBT) for Public Safety Personnel (PSP): Examination of Engagement, Outcomes, Strengths and Challenges","Inclusion Criteria:\n\n* 18 years of age or older\n* residing in a Canadian province or territory in which PSPNET is able to offer services\n* endorsing symptoms of anxiety, depression, or post-traumatic stress\n* able to access a computer and internet service\n* willing to provide a physician as emergency contact unless the participant does not have a physician and the clinician conducting the telephone screening assesses the need for an emergency contact to be low.\n\nExclusion Criteria:\n\n* high suicide risk\n* suicide attempt or hospitalization in the last year\n* primary problems with psychosis, alcohol or drug problems, mania\n* currently receiving regular psychological treatment for anxiety or depression\n* not present in Canada during treatment\n* concerns about ICBT","ALL","18 Years",{"count":19,"type":20},250,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study evaluates a transdiagnostic Internet-delivered cognitive behavioural therapy (ICBT) recently tailored for Canadian public safety personnel (PSP) reporting symptoms of depression, anxiety, or posttraumatic stress. Outcomes of interest include engagement with the intervention, changes in symptoms and functioning, and strengths and limitations of implementing ICBT with Canadian PSP.",[26,27],"Depression, Anxiety","Psychological Trauma",[29,30,31],"Internet","Cognitive Behavioral Therapy","Telemedicine","RECRUITING","2026-06-16",{"date":35,"type":36},"2026-06-18","ACTUAL",{"date":38,"type":36},"2019-12-01",{"date":40,"type":20},"2028-03-31",{"name":42,"class":43},"University of Regina","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},"100600291","enhancing-internet-delivered-cognitive-behaviour-therapy-with-additional-content-100600291","NCT07095582","Enhancing Internet-Delivered Cognitive Behaviour Therapy With Additional Content","Enhancing Therapist-Guided Internet-Delivered Cognitive Behaviour Therapy for Depression and Anxiety With Additional Content","Inclusion Criteria:\n\n* Saskatchewan resident,\n* Aged 18 years or older,\n* Self-reported difficulty with depression and\u002For anxiety,\n* Access to a computer (or other appropriate device) and the Internet,\n* Willingness to learn information and skills to self-manage mental health difficulties, and\n* Total score on UCLA-3 is greater than 5 at screening\n\nExclusion Criteria:\n\n* Current severe medical or psychiatric condition that requires immediate treatment (e.g. current mania or psychosis, actively suicidal or unable to keep themselves safe, medical condition requiring immediate surgery or other invasive treatment);\n* Unable to read and understand English (All content is provided in English and staff is English speaking)",{"count":53,"type":20},494,[23],"This study evaluates the effectiveness of additional content on loneliness offered alongside the Wellbeing Course - an internet-delivered cognitive behavioral therapy (ICBT) intervention for symptoms of depression and anxiety- in improving treatment outcomes for individuals with elevated scores on loneliness seeking treatment for depression and anxiety at a routine care online therapy clinic (the Online Therapy Unit). In this partially randomized control trial, the investigators aim to contribute to the literature by examining whether providing additional content on loneliness alongside the Wellbeing Course enhances engagement, satisfaction, and treatment outcomes among clients experiencing frequent loneliness compared to those completing only the Wellbeing Course. Over 8 weeks, participants will review course materials (with the addition of the loneliness content for those assigned to the loneliness content condition) online and complete questionnaires assessing changes in various outcomes over time.",[57,58,59],"Loneliness","Depression","Anxiety",[57,58,59,61,62,63,64,65],"Internet-delivered cognitive behavioral therapy","Randomized controlled trial","Personalized therapy","Therapist assistance","Mental health system","2026-04-28",{"date":68,"type":36},"2026-04-29",{"date":70,"type":36},"2025-06-18",{"date":72,"type":20},"2026-12",{"name":42,"class":43},2,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":21,"phases":84,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":92,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":44},"100573366","the-sleep-course-an-online-sleep-intervention-for-adults-with-self-reported-sleep-difficulties-100573366","NCT06745349","The Sleep Course: An Online Sleep Intervention for Adults With Self-reported Sleep Difficulties","The Sleep Course: Examining the Feasibility, Acceptability, and Effectiveness of an Online Sleep Intervention for Adults With Self-reported Sleep Difficulties","Inclusion Criteria:\n\n* 18 years or older;\n* Living in Saskatchewan for the treatment period;\n* Self-reported difficulty with sleep (i.e., difficulty falling, staying asleep or waking up early) causing daytime distress and or impairment;\n* Has comfort using and access to a device or computer with Internet in a private location;\n* Read and understand English;\n* Consent to Sleep Course, online therapy as provided by Unit, and associated research.\n\nExclusion Criteria:\n\n* Current severe medical or psychiatric disorder that requires immediate or alternate treatment (e.g. current and recent mania or psychosis requiring hospitalization, actively suicidal and unable to keep themselves safe, medical condition requiring immediate surgery or other invasive treatment, severe substance use);\n* Taking part in another treatment at our clinic.",{"count":83,"type":20},56,[23],"This study evaluates an internet-delivered cognitive behavioural therapy for insomnia (ICBTi) intervention, known as the Sleep Course, within a routine online therapy clinic (the Online Therapy Unit). The Sleep Course will specifically be offered to clients with self-reported sleep difficulties (i.e., falling or staying asleep or waking early) and daytime distress and or impairment. This study aims to replicate the effectiveness and acceptability of the previously evaluated Sleep Course when delivered in Australia. The investigators will also assess uptake and completion rates within the clinic as well as demographic and clinical characteristics of individuals enrolled in the Sleep Course.",[87,58,59],"Insomnia",[29,89,90,87,91,58,59],"Internet-Delivered CBT","Digital Mental Health Interventions","Sleep Difficulties",{"date":68,"type":36},{"date":94,"type":36},"2024-12-10",{"date":96,"type":20},"2026-06",{"name":42,"class":43},{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":105,"targetDuration":4,"studyType":21,"phases":107,"briefSummary":108,"conditions":109,"keywords":110,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":44},"100464894","internet-delivered-cognitive-behaviour-therapy-for-students-duration-preference-trial-100464894","NCT05333627","Internet-delivered Cognitive Behaviour Therapy for Students: Duration Preference Trial","Internet-delivered Cognitive Behaviour Therapy for Post-Secondary Students: Preference Trial for Flexible, 5-Week, and 8-Week Options","Inclusion Criteria:\n\n* registered as a student at a post-secondary institution in Saskatchewan; over the age of 18; endorse symptoms of depression (score of 5 or greater on the PHQ-9) and\u002For anxiety (score of 5 or greater on the GAD-7); and be able to access computers and the Internet and be comfortable using them\n\nExclusion Criteria:\n\n* high risk of suicide or hospitalization for mental health in previous 12 months; unmanaged alcohol or drug use problems; severe psychiatric illness that is not managed (e.g. psychosis or mania); or receiving other psychological services more than twice per month",{"count":106,"type":20},200,[23],"There is growing evidence for the effectiveness of internet-delivered cognitive behaviour therapy (ICBT) for post-secondary students with symptoms of depression and anxiety. In ICBT, clients review structured online content over several weeks to learn strategies and skills to manage their symptoms. Low treatment completion rates remain a concern for post-secondary students, so it is possible that existing treatment protocols do not offer enough flexibility for students' needs and preferences.\n\nThis trial will examine students' preferences for different course options (fast-track, 5-week, and 8-week) and compare enrollment, adherence, and outcomes of students who pick each of the three options. In all three options, students will receive optional therapist support, in which the assigned therapist only contacts the student on weeks where the student sends the therapist a message. This trial will help inform the delivery of flexible treatment options for post-secondary students in a routine care setting.",[58,59],[111,112,113,114,115,116],"anxiety","depression","post-secondary students","internet-delivered cognitive behaviour therapy","transdiagnostic","preference trial",{"date":118,"type":36},"2026-05-05",{"date":120,"type":36},"2020-11-01",{"date":122,"type":20},"2027-04-30",{"name":42,"class":43},{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":131,"targetDuration":4,"studyType":21,"phases":133,"briefSummary":134,"conditions":135,"keywords":137,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":138,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":142,"locationsCount":44},"100388262","internet-delivered-cognitive-behaviour-therapy-for-ptsd-among-public-safety-personnel-100388262","NCT04335487","Internet-Delivered Cognitive Behaviour Therapy for PTSD Among Public Safety Personnel","Internet-Delivered Cognitive Behaviour Therapy for PTSD Among Public Safety Personnel: Open Cohort Preference Trial for Transdiagnostic or Disorder-Specific Therapy","Inclusion Criteria:\n\n* 18 years of age or older\n* residing in Saskatchewan for the duration of the intervention\n* endorsing symptoms of post-traumatic stress\n* able to access a computer and internet service\n* willing to provide a physician as emergency contact\n\nExclusion Criteria:\n\n* high suicide risk\n* suicide attempt or hospitalization in the last year\n* primary problems with psychosis, alcohol or drug problems, or mania\n* currently receiving regular psychological treatment\n* concerns about ICBT",{"count":132,"type":20},300,[23],"This study evaluates two Internet-delivered cognitive behavioural therapy (ICBT) interventions: one for symptoms of posttraumatic stress disorder (PTSD) and one for symptoms of anxiety, depression, and PTSD. Both interventions have been tailored for Canadian public safety personnel (PSP). Outcomes of interest include preference for disorder-specific or transdiagnostic care, engagement with the interventions, changes in symptoms and functioning, and strengths and limitations of implementing ICBT with Canadian PSP.",[136,58,59],"Posttraumatic Stress",[29,30,31],{"date":68,"type":36},{"date":140,"type":36},"2020-07-06",{"date":40,"type":20},{"name":42,"class":43},{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":4,"eligibilityCriteria":149,"healthyVolunteers":150,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":151,"targetDuration":4,"studyType":21,"phases":153,"briefSummary":154,"conditions":155,"keywords":156,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":164,"locationsCount":44},"100594571","the-public-safety-personnel-psp-sleep-course-an-online-sleep-intervention-for-psp-100594571","NCT07021183","The Public Safety Personnel (PSP) Sleep Course: An Online Sleep Intervention for PSP.","Uptake, Acceptability, and Effectiveness of Internet-Delivered Cognitive Behaviour Therapy for Public Safety Personnel With Self-Reported Sleep Difficulties","Inclusion Criteria:\n\n* 18 years of age or older\n* Current or former paid or volunteer PSP\n* Living in a province in Canada where PSPNET offers the Sleep Couse for the treatment period\n* Willingness to learn information and skills to self-manage sleep difficulties\n* Have internet access\n* Consent to Sleep Course, online therapy as provided by PSPNET, and associated research\n\nExclusion Criteria:\n\n* Current severe medical or psychiatric disorder (e.g. current and recent mania or psychosis, recent hospitalization for mental health concerns, actively suicidal, medical condition client thinks will interfere with treatment, severe substance use)\n* Unable to read and understand English. (All content is provided in English and staff is English speaking; pending findings of the research PSPNET will explore translating the course into French)",true,{"count":152,"type":20},60,[23],"This study evaluates an internet-delivered cognitive behavioural therapy for insomnia (ICBTi) intervention, known as the Sleep Course, adapted for public safety personnel (PSP) experiencing sleep difficulties. The study seeks to replicate prior results from an Australian version of the Sleep Course assessing its effectiveness and acceptability when offered to PSP.",[87],[29,89,90,87,91,58,59,157],"Public Safety Personnel","2026-04-09",{"date":160,"type":36},"2026-04-14",{"date":162,"type":36},"2025-03-06",{"date":40,"type":20},{"name":42,"class":43},{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":150,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":172,"targetDuration":4,"studyType":21,"phases":174,"briefSummary":175,"conditions":176,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":178,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":182,"locationsCount":44},"100539010","assessing-social-learning-and-course-delivery-timing-in-internet-delivered-cognitive-behaviour-therapy-for-public-safety-personnel-100539010","NCT06298279","Assessing Social Learning and Course Delivery Timing in Internet-delivered Cognitive Behaviour Therapy for Public Safety Personnel","A Randomized Factorial Trial of Internet-delivered Cognitive Behaviour Therapy for Public Safety Personnel: Examining the Impact of Content Delivery Method","Inclusion Criteria:\n\n* At least 18 years of age\n* Current or former public safety personnel (or public safety personnel trainee)\n* Residing in Canada at time of enrollment\n* Has regular access to the internet\n* Confirms intent to participate in study\n\nExclusion Criteria:\n\n* Not 18 years of age or older\n* Not a current or former public safety personnel (or public safety personnel trainee)\n* Not residing in Canada at time of enrollment\n* Does not have regular access to the internet",{"count":173,"type":20},164,[23],"This study is a randomized factorial trial designed to evaluate unguided (i.e., purely self-help), transdiagnostic internet delivered cognitive behaviour therapy tailored for public safety personnel with tunneled of personalized course delivery and with or without the incorporation of social learning resources.",[58,59,177],"Stress Disorders, Post-Traumatic",{"date":160,"type":36},{"date":180,"type":36},"2024-03-12",{"date":122,"type":20},{"name":42,"class":43},{"id":184,"slug":185,"hasResults":11,"nctId":186,"briefTitle":187,"officialTitle":188,"acronym":4,"eligibilityCriteria":189,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":190,"targetDuration":4,"studyType":21,"phases":192,"briefSummary":193,"conditions":194,"keywords":196,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":200,"lastUpdatePostDateStruct":201,"startDateStruct":203,"completionDateStruct":205,"leadSponsor":206,"locationsCount":74},"100610930","therapist-guided-internet-delivered-cbt-for-chronic-conditions-predictors-of-change-100610930","NCT07233980","Therapist-Guided Internet-Delivered CBT for Chronic Conditions: Predictors of Change","Therapist-Guided Internet-Delivered Cognitive Behaviour Therapy (CBT) for Chronic Conditions (Chronic Conditions Course; CCC): Single-Group Predictors of Change in Routine Care","Inclusion Criteria:\n\n* Saskatchewan resident (as funding is provided by Saskatchewan government);\n* Aged 18 years or older;\n* self-reported diagnosed with chronic physical health condition affecting mental health;\n* Access to a computer and the Internet;\n* Consent to treatment\u002Fresearch\n\nExclusion Criteria:\n\n* Current severe psychiatric or medical condition that requires immediate treatment and or would interfere with participation (e.g. current mania or psychosis, actively suicidal or unable to keep themselves safe, medical condition requiring immediate surgery or other invasive treatment, cognitive difficulties);\n* Taking part in another treatment in our clinic;\n* Living outside of Saskatchewan",{"count":191,"type":20},260,[23],"Chronic health conditions are common, disabling, and often co-occur with depression and anxiety. Internet-delivered cognitive behaviour therapy (ICBT) reduces barriers to treatment and has been adapted for chronic conditions. A transdiagnostic approach is promising because it is both effective and convenient in that clients with diverse conditions receive the same program. Both therapist-guided and self-guided formats have been found effective; however, in routine care therapist support is most common to ensure that clients have support to personalize care.\n\nThis study evaluates the therapist-guided Chronic Conditions Course (CCC) and examines predictors of change. Past research shows that the most robust predictors of ICBT outcomes are baseline severity, adherence, credibility, and working alliance. However, few studies of ICBT for chronic conditions have examined predictors together. Moreover, the researchers are aware of no studies that have examined these core predictors in routine delivery of ICBT for those with chronic health conditions alongside other predictors-such as changes in thoughts and adaptive actions. A limitation of past work is that predictor analyses were typically secondary to trials designed for other purposes. This study directly addresses that gap by prospectively modeling predictors of change in routine care.",[195],"Chronic Physical Health Conditions",[197,59,58,198,64,199],"Internet-delivered cognitive behavior therapy","Chronic physical health conditions","Predictors","2025-11-24",{"date":202,"type":36},"2025-12-02",{"date":204,"type":36},"2025-10-08",{"date":72,"type":20},{"name":42,"class":43},{"id":208,"slug":209,"hasResults":11,"nctId":210,"briefTitle":211,"officialTitle":212,"acronym":4,"eligibilityCriteria":213,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":214,"targetDuration":4,"studyType":21,"phases":215,"briefSummary":216,"conditions":217,"keywords":218,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":222,"lastUpdatePostDateStruct":223,"startDateStruct":225,"completionDateStruct":227,"leadSponsor":229,"locationsCount":44},"100583850","internet-delivered-cognitive-behaviour-therapy-for-depression-and-anxiety-in-perinatal-parents-100583850","NCT06881693","Internet-Delivered Cognitive Behaviour Therapy for Depression and Anxiety in Perinatal Parents","Optimizing Therapist-guided Internet-delivered Cognitive Behaviour Therapy for New and Expecting Parents","Inclusion Criteria:\n\n* Become the guardian of an infant in the last 24 month by birth or adoption\u002Ffostering or are expecting the birth of an infant as a birthing parent or partner;\n* Self-reported difficulty with depression and\u002For anxiety;\n* Are aged 18 years or older; or 16 if participant meets criteria to be treated as a mature minor based on Saskatchewan legislation;\n* Willingness to learn information and skills to self-manage mental health difficulties, consent to course and associated research.\n\nExclusion Criteria:\n\n* Current severe medical or psychiatric condition that requires immediate treatment (e.g. current mania or psychosis, actively suicidal or unable to keep themselves safe, medical condition requiring immediate surgery or other invasive treatment);\n* Living outside of Saskatchewan;\n* Unable to read and understand English. (All content is provided in English and staff is English speaking; it is cost prohibitive at this time to provide the complete service in languages other than English).",{"count":152,"type":20},[23],"This study evaluates the effectiveness of the Wellbeing Course for New and Expecting Parents (WCNEP), an internet-delivered cognitive behavioral therapy (ICBT) intervention, in reducing symptoms of anxiety and depression in perinatal parents, within a routine care online therapy clinic (the Online Therapy Unit). The study aims to assess treatment uptake, perceptions, feasibility, and effectiveness of the WCNEP in routine care among birthing and non-birthing parents. Over the duration of 8 weeks, participants will review course materials online and respond to questionnaires aimed at assessing changes in various outcomes over time.",[59,58],[59,58,219,220,221],"Internet-delivered cognitive behaviour therapy","Patient stories","Perinatal mental health","2025-11-14",{"date":224,"type":36},"2025-11-17",{"date":226,"type":36},"2025-02-24",{"date":228,"type":20},"2026-06-30",{"name":42,"class":43},{"id":231,"slug":232,"hasResults":11,"nctId":233,"briefTitle":234,"officialTitle":235,"acronym":4,"eligibilityCriteria":236,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":237,"targetDuration":4,"studyType":239,"phases":4,"briefSummary":240,"conditions":241,"keywords":242,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":222,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":248,"leadSponsor":250,"locationsCount":44},"100529788","observations-of-a-brief-online-psychological-intervention-among-people-seeking-online-mental-health-services-100529788","NCT06178328","Observations of a Brief Online Psychological Intervention Among People Seeking Online Mental Health Services","'Things You Do': An Observational Pilot Trial of a Brief Psychological Intervention Among People Seeking Online Mental Health Services","Inclusion Criteria:\n\n* Canadian resident;\n* Aged 18 years or older;\n* Seeking services for mental health concerns\n\nExclusion Criteria:\n\n* Living outside of Canada\n* Unable to read and understand English",{"count":238,"type":20},50,"OBSERVATIONAL","Since 2012, the Online Therapy Unit has been offering Internet-delivered cognitive behaviour therapy (ICBT). ICBT represents a convenient method for individuals to access care for depression and anxiety. In ICBT, clients receive access to standardized lessons that provide the same information and skills as traditional face-to-face CBT. ICBT courses often span 6-12 weeks. There is now growing evidence that clients with symptoms of depression and anxiety can benefit from a single session brief intervention that offers practical strategies for improving mental health, but the investigators are uncertain about the interest in such a lesson among those seeking online mental health care. The Things You Do Course, therefore, is designed to provide clients with 5 key actions that clients can take to improve their emotional wellbeing.\n\nIn this study, the Online Therapy Unit (OTU) is examining how effective the Things You Do Course is in helping clients manage their symptoms of depression and anxiety and improve their emotional wellbeing. The OTU is also exploring the extent to which clients are satisfied with the course, and what factors contribute to improvements in symptoms, as measured by a number of questionnaires. The research will ultimately be used to improve how the OTU will deliver ICBT and to inform whether to include the single session course within existing online mental health service options.",[26],[114,243],"brief intervention",{"date":245,"type":36},"2025-11-19",{"date":247,"type":36},"2023-11-17",{"date":249,"type":20},"2026-09",{"name":42,"class":43},{"id":252,"slug":253,"hasResults":11,"nctId":254,"briefTitle":255,"officialTitle":256,"acronym":4,"eligibilityCriteria":257,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":258,"targetDuration":4,"studyType":21,"phases":260,"briefSummary":261,"conditions":262,"keywords":264,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":266,"lastUpdatePostDateStruct":267,"startDateStruct":269,"completionDateStruct":271,"leadSponsor":273,"locationsCount":44},"100594561","adaptive-actions-and-alcohol-use-outcomes-during-internet-delivered-cognitive-behaviour-therapy-100594561","NCT07021053","Adaptive Actions and Alcohol Use Outcomes During Internet-delivered Cognitive Behaviour Therapy","Adaptive Actions and Alcohol Use Outcomes During Internet-delivered Cognitive Behaviour Therapy: An Observational Study During Routine Care","Inclusion Criteria:\n\n* Be a resident of Canada\n* Be 18 years or older\n* Have access to a computer or appropriate device and the internet\n* Endorse alcohol misuse\n\nExclusion Criteria:\n\n* Current severe medical or psychiatric problem that requires immediate or alternate treatment (e.g. current and recent mania or psychosis requiring hospitalization, actively suicidal and unable to keep themselves safe, medical condition requiring immediate surgery or other invasive treatment, severe substance use, severe cognitive impairment);\n* Currently receiving or expecting to receive individual alcohol treatment more than twice per month\n* Other treatment in our clinic\n* Unable to read and understand English. (All content is provided in English and staff is English speaking; it is cost prohibitive at this time to provide the complete service in languages other than English)",{"count":259,"type":20},165,[23],"This observational study investigates an Internet-delivered Cognitive Behaviour Therapy (ICBT) intervention for alcohol misuse, called the Alcohol Change Course Enhanced (ACCE). The intervention will be offered through the Online Therapy Unit, which is a routine care ICBT clinic. The primary objective of the study is to examine whether engagement in adaptive actions measured by the Things You Do Questionnaire (TYDQ), including healthy thinking, meaningful activities, social connections, healthy habits and goal setting - increase during ICBT for alcohol misuse. Using data collected during routine care, the relationship between adaptive actions and alcohol use will be investigated, and specifically explore if the frequency of adaptive actions increases as alcohol use reduces during the intervention.",[263],"Alcohol Misuse",[219,265],"Alcohol misuse","2025-08-15",{"date":268,"type":36},"2025-08-21",{"date":270,"type":36},"2025-05-14",{"date":272,"type":20},"2026-05-14",{"name":42,"class":43},{"id":275,"slug":276,"hasResults":11,"nctId":277,"briefTitle":278,"officialTitle":279,"acronym":280,"eligibilityCriteria":281,"healthyVolunteers":11,"sex":16,"minAge":282,"maxAge":283,"enrollmentInfo":284,"targetDuration":4,"studyType":21,"phases":286,"briefSummary":287,"conditions":288,"keywords":293,"overallStatus":300,"whyStopped":4,"lastUpdateSubmitDate":301,"lastUpdatePostDateStruct":302,"startDateStruct":304,"completionDateStruct":306,"leadSponsor":308,"locationsCount":74},"100517648","internet-delivered-cystic-fibrosis-mental-health-prevention-wellness-resource-program-how-does-it-work-100517648","NCT06020274","Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, Resource Program: How Does it Work?","Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, Resource (iCF-PWR) Program: How Does it Work?","iCF-PWR","Inclusion Criteria:\n\n* between the ages of 8 and 12\n* have a CF diagnosis or are a sibling of a child with CF\n* can speak and read English. The research team does not have competence in other languages, further our program is delivered in English\n\nExclusion Criteria:\n\n* have a severe cognitive impairment or a major comorbid medical or psychiatric illness, as this may impede their ability to fully participate in the program and evaluation process","8 Years","12 Years",{"count":285,"type":20},120,[23],"The goal of the clinical trial is to test whether a mental health program that is delivered through the Internet works well for children and adolescents with cystic fibrosis (CF) and their healthy siblings. The main questions it aims to answer are:\n\n* Does the program improve the mental health such as depression and anxiety symptoms?\n* Does the program improve overall quality of life?\n* Does the program improve self-efficacy - an individual's belief in their ability to complete tasks to achieve their goals?\n\nParticipants will:\n\n* Fill out an online survey asking questions about their personal and health information, as well as their mental health before the program\n* Complete the online mental health program\n* Fill out an online survey asking questions about their mental health after completing the program, and 1-month and 3-months following completing the program\n\nParticipants be compared against another group of children with CF and their healthy siblings who are on a waitlist and receiving usual CF treatment. Researchers will compare participants scores before starting the program with their scores immediately following completing the program, 1-month, and 3-month after completing the program. Researchers hope to develop a program that improves mental health, quality of life, self-efficacy, and knowledge about CF.",[289,290,291,292],"Cystic Fibrosis in Children","Siblings","Mental Health","Internet-based Intervention",[294,295,296,297,298,299,111,112],"cystic fibrosis","child","adolescent","siblings","mental health","Internet-based intervention","NOT_YET_RECRUITING","2025-06-05",{"date":303,"type":36},"2025-06-10",{"date":305,"type":20},"2025-06-01",{"date":307,"type":20},"2027-06-30",{"name":42,"class":43},{"id":310,"slug":311,"hasResults":11,"nctId":312,"briefTitle":313,"officialTitle":314,"acronym":4,"eligibilityCriteria":315,"healthyVolunteers":11,"sex":316,"minAge":17,"maxAge":317,"enrollmentInfo":318,"targetDuration":4,"studyType":21,"phases":319,"briefSummary":320,"conditions":321,"keywords":324,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":328,"lastUpdatePostDateStruct":329,"startDateStruct":331,"completionDateStruct":333,"leadSponsor":335,"locationsCount":74},"100565915","pilot-study-of-the-thriving-with-pmds-program-100565915","NCT06648382","Pilot Study of the 'Thriving With PMDs' Program","Pilot Test of a Self-Directed Psychotherapy Program for Premenstrual Disorders","Inclusion Criteria:\n\n* Ages 18-42\n* Either meeting diagnostic criteria for premenstrual dysphoric disorder (to be confirmed by researchers through daily symptom ratings for two menstrual cycles) or major depressive disorder with perimenstrual exacerbation (i.e. at least a 30% increase in 4 symptoms in the perimenstrual phase)\n\nExclusion Criteria:\n\n* Taking oral contraceptives\n* Currently in psychotherapy","FEMALE","42 Years",{"count":238,"type":20},[23],"This study is testing a self-help mental health program that was designed to help people cope with the challenges of living with a premenstrual disorder. Individuals with a premenstrual disorder - either premenstrual dysphoric disorder or premenstrual exacerbation of depression - will track their daily symptoms for two menstrual cycles before they complete the program, throughout the two-cycle program, and for an additional two cycles after accessing the program. This will allow the research team to compare their symptoms before and after accessing the program.",[322,323],"Premenstrual Disorder","Premenstrual Dysphoric Disorder",[325,326,327],"Psychotherapy","Premenstrual disorder","Premenstrual dysphoric disorder","2025-04-03",{"date":330,"type":36},"2025-04-06",{"date":332,"type":36},"2024-10-15",{"date":334,"type":20},"2025-10",{"name":42,"class":43},{"id":337,"slug":338,"hasResults":11,"nctId":339,"briefTitle":340,"officialTitle":341,"acronym":4,"eligibilityCriteria":342,"healthyVolunteers":150,"sex":16,"minAge":343,"maxAge":4,"enrollmentInfo":344,"targetDuration":4,"studyType":21,"phases":346,"briefSummary":347,"conditions":348,"keywords":350,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":356,"lastUpdatePostDateStruct":357,"startDateStruct":359,"completionDateStruct":361,"leadSponsor":363,"locationsCount":44},"100562711","effects-of-resistance-band-training-and-creatine-and-whey-protein-100562711","NCT06606717","Effects of Resistance-band Training and Creatine and Whey Protein","Effects of Resistance-band Training and Nutritional Supplementation in Healthy Older Adults","Inclusion Criteria:\n\n* Untrained (defined as those performing ≤ 1 resistance training session per week for ≥ 6 weeks prior to the start of the study)\n\nExclusion Criteria:\n\n* Taking creatine monohydrate within 30 days prior to the start of the study\n* Currently ingesting whey protein\n* Have pre-existing allergies to latex, fruit, dairy, nuts, seafood and mustard","50 Years",{"count":345,"type":20},36,[23],"The primary purpose of this research is to compare the effects of creatine monohydrate and\u002For whey protein supplementation during the first 10 weeks of a 20-week resistance-band training program on measures of body composition (whole-body lean tissue mass, total body water), arm and leg muscle thickness, upper- and lower-body muscle performance (i.e., strength, endurance) and functional ability (walking speed, balance). A secondary purpose of this research is to examine the effects of supplementation cessation (i.e., no creatine and\u002For whey protein supplementation) during the final 10 weeks of the 20-week resistance-band training program on these measures.",[349],"Sarcopenia in Elderly",[351,352,353,354,355],"Resistance Exercise","Creatine","Whey Protein","Strength","Lean Mass","2024-09-18",{"date":358,"type":36},"2024-09-23",{"date":360,"type":36},"2024-08-18",{"date":362,"type":20},"2025-07",{"name":42,"class":43},{"id":365,"slug":366,"hasResults":11,"nctId":367,"briefTitle":368,"officialTitle":369,"acronym":4,"eligibilityCriteria":370,"healthyVolunteers":150,"sex":16,"minAge":343,"maxAge":4,"enrollmentInfo":371,"targetDuration":4,"studyType":21,"phases":373,"briefSummary":374,"conditions":375,"keywords":377,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":356,"lastUpdatePostDateStruct":380,"startDateStruct":381,"completionDateStruct":383,"leadSponsor":385,"locationsCount":44},"100562710","effects-of-resistance-band-training-and-creatine-supplementation-strategies-in-healthy-older-adults-100562710","NCT06606704","Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adults","Effects of Resistance-band Training and Creatine Supplementation in Healthy Older Adults","Inclusion Criteria:\n\n* if you are 50 years of age and older\n* if you have not been performing more than 1 resistance training session per week for the past 6 weeks or more.\n\nExclusion Criteria:\n\n* if you have taken creatine supplements within 30 days prior to the start of the study\n* if you have pre-existing allergies to the placebo (corn-starch maltodextrin).",{"count":372,"type":20},52,[23],"The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).\n\nA secondary purpose of this research is to examine the effects of bolus ingestion of creatine (5 grams) compared to intermittent ingestion of creatine (2 x 2.5 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).",[376],"Aging",[376,352,378,379,354],"Resistance-Bands","Muscle",{"date":358,"type":36},{"date":382,"type":36},"2024-08-20",{"date":384,"type":20},"2025-07-30",{"name":42,"class":43},{"id":387,"slug":388,"hasResults":11,"nctId":389,"briefTitle":390,"officialTitle":391,"acronym":4,"eligibilityCriteria":392,"healthyVolunteers":150,"sex":16,"minAge":17,"maxAge":393,"enrollmentInfo":394,"targetDuration":4,"studyType":21,"phases":396,"briefSummary":397,"conditions":398,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":400,"lastUpdatePostDateStruct":401,"startDateStruct":403,"completionDateStruct":404,"leadSponsor":406,"locationsCount":44},"100562563","creatine-supplementation-in-young-healthy-adults-100562563","NCT06604793","Creatine Supplementation in Young Healthy Adults","Effects of Equal-volume Creatine Supplementation With Different Dosing Strategies on Body Composition and Muscle Performance in Young Healthy Adults","Inclusion Criteria:\n\n* if you are 18-39 years of age\n* if you have not been performing resistance training for at least 4 weeks prior to the start of the study.\n\nExclusion Criteria:\n\n* if you are pregnant or nursing\n* have taken creatine monohydrate within 30 days prior to the start of the study\n* if you have pre-existing allergies to the placebo (corn-starch maltodextrin)","39 Years",{"count":395,"type":20},42,[23],"The purpose is to compare the effects of bolus ingestion (5 grams) vs. intermittent ingestion (2 x 2.5 grams) of creatine supplementation vs. placebo for 21 days on measures of body composition (lean tissue mass-indicator of muscle mass, total body water) and muscle performance (i.e., power, strength, endurance).",[399],"Improve Muscle Performance in Young Adults","2024-09-17",{"date":402,"type":36},"2024-09-20",{"date":382,"type":36},{"date":405,"type":20},"2025-01-31",{"name":42,"class":43},{"id":408,"slug":409,"hasResults":11,"nctId":410,"briefTitle":411,"officialTitle":411,"acronym":4,"eligibilityCriteria":412,"healthyVolunteers":150,"sex":16,"minAge":413,"maxAge":414,"enrollmentInfo":415,"targetDuration":4,"studyType":21,"phases":417,"briefSummary":418,"conditions":419,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":428,"lastUpdatePostDateStruct":429,"startDateStruct":431,"completionDateStruct":433,"leadSponsor":435,"locationsCount":44},"100479786","risk-and-resiliency-factors-in-the-rcmp-a-prospective-investigation-100479786","NCT05527509","Risk and Resiliency Factors in the RCMP: A Prospective Investigation","Inclusion Criteria:\n\n* Cadets starting the RCMP Cadet Training Program\n\nExclusion Criteria:\n\n* Anyone other than cadets starting the RCMP Cadet Training Program","19 Years","57 Years",{"count":416,"type":20},960,[23],"The Royal Canadian Mounted Police (RCMP), like all public safety personnel (PSP), are frequently exposed to potentially psychologically traumatic events that contribute to posttraumatic stress injuries (PTSI). Addressing PTSI is impeded by the limited available research. The RCMP are working to build evidence-based solutions to PTSI and other mental health challenges facing their members, which by extension will help all PSP, as part of the Canadian Government Federal Framework on Posttraumatic Stress Disorder. A key element is the \"Longitudinal Study of Operational Stress Injuries \u002F Étude longitudinale sur les traumatismes liés au stress opérationnel\", a study which has been renamed \"Risk and Resiliency Factors in the RCMP: A Prospective Investigation\", and is referred to as the \"RCMP Study\" for short. The RCMP Study has been detailed online (www.rcmpstudy.ca) and in a recently published peer-reviewed protocol paper, \"The Royal Canadian Mounted Police (RCMP) Study: protocol for a prospective investigation of mental health risk and resilience factors\" (https:\u002F\u002Fdoi.org\u002F10.24095\u002Fhpcdp.42.8.02). The RCMP Study, part of the concerted efforts by the RCMP to reduce PTSI by improving access to evidence-based assessments, treatments, and training as well as participant recruitment and RCMP Study developments to date. The RCMP Study has been designed to (1) develop, deploy and assess the impact of a system for ongoing annual, monthly and daily evidence-based assessments; (2) evaluate associations between demographic variables and PTSI; (3) longitudinally assess individual differences associated with PTSI; (4) augment the RCMP Cadet Training Program with skills to proactively mitigate PTSI; and (5) assess the impact of the augmented training condition (ATC) versus the standard training condition (STC). Participants in the STC (n = 480) and ATC (n = 480) are assessed before and after training and annually for 5 years on their deployment date; they also complete brief monthly and daily surveys. The RCMP Study results are expected to benefit the mental health of all participants, RCMP and PSP by reducing PTSI among all who serve.",[420,421,422,423,424,425,426,427],"Posttraumatic Stress Disorder","Major Depressive Disorder","Panic Disorder","Generalized Anxiety Disorder","Trauma","Traumatic Stress Disorder","Trauma and Stress Related Disorders","Vicarious Trauma","2023-11-27",{"date":430,"type":36},"2023-11-28",{"date":432,"type":36},"2019-04-22",{"date":434,"type":20},"2029-12",{"name":42,"class":43},""]