[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Rzeszow\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":203},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,49,74,99,124,150,179],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100642196","high-intensity-laser-therapy-hilt-in-patients-with-knee-osteoarthritis-100642196",false,"NCT07661407","High-Intensity Laser Therapy (HILT) in Patients With Knee Osteoarthritis","Assessment of the Effectiveness of High-Intensity Laser Therapy (HILT) in the Treatment of Knee Osteoarthritis: A Randomized Placebo-Controlled Trial","Inclusion Criteria:\n\n* Radiographically confirmed knee osteoarthritis\n* Mild-to-moderate disease severity\n* Pain ≥4 on VAS for at least 3 months\n* Ability to participate in physiotherapy\n* Informed consent\n\nExclusion Criteria:\n\n* Advanced OA requiring surgery\n* Previous knee arthroplasty\n* Knee instability\n* Acute inflammation\n* Neurological disorders affecting gait\n* Neuropathies or myopathies\n* Active inflammatory arthritis\n* Recent lower-limb injury (\\\u003C6 months)\n* Intra-articular injections within 3 months\n* Cancer, pregnancy, epilepsy\n* Electronic implants or pacemaker\n* Active local infection","ALL","40 Years","75 Years",{"count":20,"type":21},72,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized placebo-controlled trial aims to evaluate the effectiveness of High-Intensity Laser Therapy (HILT) as an adjunct to standard outpatient physiotherapy in patients with knee osteoarthritis. Seventy-two participants will be randomly assigned to receive either conventional physiotherapy combined with active HILT or conventional physiotherapy combined with sham HILT. Outcomes related to pain, knee function, physical performance, muscle strength, range of motion, psychosocial factors, quality of life and body composition will be assessed at baseline, after the intervention, and at 8-week follow-up.",[27],"Knee Osteoarthritis (Knee OA)",[29,30,31,32,33,34,35,36],"High-Intensity Laser Therapy","HILT","Knee Osteoarthritis","Gonarthrosis","Physiotherapy","Pain","KOOS","Randomized Controlled Trial","NOT_YET_RECRUITING","2026-06-24",{"date":40,"type":41},"2026-06-29","ACTUAL",{"date":43,"type":21},"2026-07-03",{"date":45,"type":21},"2028-03-31",{"name":47,"class":48},"University of Rzeszow","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100636679","effectiveness-of-vr-rehabilitation-for-people-with-asymmetrical-gait-patterns-100636679","NCT07568821","Effectiveness of VR Rehabilitation for People With Asymmetrical Gait Patterns","Evaluation of the Effectiveness of Rehabilitation in Patients With Gait Pattern Asymmetry Using a Virtual Reality","Inclusion Criteria:\n\n* Diagnosed and clinically confirmed gait pattern asymmetry in the course of neurological diseases\n* Informed consent to participate in the study and willingness to comply with rehabilitation recommendations\n\nExclusion Criteria:\n\n* Active rheumatic diseases, cancer, advanced diabetes, cardiovascular diseases, and other conditions that may affect the safety and effectiveness of rehabilitation\n* Contraindications to VR therapy (epilepsy, motion sickness, dizziness, nausea)\n* Lower limb injuries or surgeries within the last 6 months\n* Severe mental disorders preventing understanding of instructions\n* Lack of informed consent to participate in the study","20 Years","65 Years",{"count":59,"type":21},40,[24],"A randomized comparative study will be conducted to evaluate the rehabilitation process using a VR-based application versus conventional therapy in 40 patients (sample size determined using a sample size calculator). After meeting the eligibility criteria, participants will be randomly assigned to two groups: the experimental group (20 patients with gait pattern asymmetry), performing a gait training program using a VR rehabilitation application, and the control group (20 patients with gait pattern asymmetry), performing only a conventional gait training program.\n\nParticipants in both groups will take part in a 2-week rehabilitation program (Monday to Friday), with daily training sessions lasting up to 2 hours. Patient assessment will be conducted twice: an initial evaluation before the start of the intervention (Assessment I) and a follow-up evaluation after completion of the 2-week program (Assessment II), at the same time of day, under the same conditions, and using the same measurement tools.",[63,64,65],"Disability Evaluation","Recovery of Function","Rehabilitation","2026-05-05",{"date":68,"type":41},"2026-05-11",{"date":70,"type":21},"2027-03-01",{"date":72,"type":21},"2027-08-01",{"name":47,"class":48},{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},"100613126","fnirs-neurofeedback-for-post-stroke-hand-rehabilitation-100613126","NCT07262528","fNIRS Neurofeedback for Post-stroke Hand Rehabilitation","Hand Rehabilitation in People With Hemiparesis After a Stroke Using 3D Imaging With fNIRS Neurofeedback","Inclusion Criteria:\n\n* individuals with hemiparesis after a first ischemic stroke,\n* subacute stroke period (no longer than 3 months),\n* upper limb paresis rated 2-4 by Brunnstrom recovery stages,\n* participants aged 18 to 70 years,\n* consent to participate in the study.\n\nExclusion Criteria:\n\n* unstable general condition,\n* visual field disorders,\n* inability to sit independently,\n* cognitive impairment (Mini-Mental State Examination, MMSE \\> 24).","18 Years","70 Years",{"count":84,"type":21},30,[24],"Cardiovascular diseases are one of the main causes of disability. Among post-stroke individuals, 80% experience upper limb dysfunction, while only 5% to 20% of individuals regain full limb and hand function. The purpose of this study is to evaluate the effects of hand rehabilitation of post-stroke individuals using HEG Neurofeedback The study will include 30 participants in the early sub-acute phase post-stroke, who will be assigned to either the study group or the control group. Participants in the experimental group will follow a rehabilitation program extended with HEG Neurofeedback training, while participants in the control group will follow the standard rehabilitation program.\n\nThe HEG Neurofeedback therapy equipment will be supplemented with new hand therapy software. During the exercises, patients will focus on a discussed and presented task, and once the expected level of concentration is reached, the software will trigger a virtual hand performing a finger flexion movement.\n\nMotor control of the hand will be assessed using the Fugl-Meyer Scale and Brunnström recovery stages.",[88],"Stroke","RECRUITING","2026-04-20",{"date":92,"type":41},"2026-04-21",{"date":94,"type":41},"2025-12-01",{"date":96,"type":21},"2026-05-06",{"name":47,"class":48},1,{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":57,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":108,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":98},"100628551","virtual-reality-based-rehabilitation-versus-conventional-therapy-in-patients-with-chronic-low-back-pain-100628551","NCT07463105","Virtual Reality-Based Rehabilitation Versus Conventional Therapy in Patients With Chronic Low Back Pain","Effects of Virtual Reality-Based Rehabilitation Compared With Conventional Physiotherapy on Motor and Psychosocial Function in Patients With Chronic Low Back Pain: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of chronic low back pain lasting at least 3 months\n* Average pain intensity ≥4\u002F10 during the previous week on the Numeric Rating Scale (NRS)\n* Age between 40 and 65 years\n* Ability to walk independently without assistive devices\n* Functional disability related to low back pain defined as Oswestry Disability Index (ODI) ≥15%\n* No contraindications to participation in a physiotherapy program or virtual reality training\n* Ability to understand study procedures and follow instructions\n* Written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Acute low back pain or pain lasting less than 3 months\n* Neurological, orthopedic, rheumatological, oncological diseases or active inflammatory conditions that may affect study outcomes\n* Cognitive impairment limiting the ability to understand instructions or participate in rehabilitation\n* Contraindications to virtual reality training such as severe dizziness, nausea, epilepsy, or severe visual or auditory impairment\n* Contraindications to body composition analysis (e.g., implanted cardiac pacemaker or other electronic implants)\n* Unstable medical condition or uncontrolled cardiovascular or respiratory disorders preventing participation in rehabilitation\n* Participation in other rehabilitation programs during the study period\n* Failure to complete the four-week rehabilitation program\n* Lack of written informed consent",{"count":107,"type":21},80,[24],"This study aims to evaluate the effectiveness of rehabilitation using virtual reality compared with conventional physiotherapy in patients with chronic low back pain. The study will be conducted as a prospective, randomized controlled trial including 80 patients aged 40-65 years diagnosed with chronic low back pain lasting at least three months. Participants will be randomly assigned to two groups: an experimental group receiving conventional rehabilitation supplemented with non-immersive virtual reality training using the Tecnobody Homing Studio system, and a control group receiving conventional rehabilitation alone.\n\nBoth groups will participate in a four-week rehabilitation program. The virtual reality training will replace a portion of conventional exercises and will focus on improving movement quality, postural control, coordination, and functional mobility through interactive tasks with visual and auditory biofeedback. The system utilizes a 3D camera enabling markerless motion analysis and real-time visual feedback to support movement correction and identification of functional deficits.\n\nOutcome measures will include assessments of balance, posture, joint mobility, lower limb strength and endurance, pain intensity, pressure pain threshold, kinesiophobia, perceived stress, anxiety and depression, functional disability, quality of life, and motivation for physical activity. Measurements will be conducted at baseline, immediately after completion of the four-week rehabilitation program, and at an eight-week follow-up.\n\nThe results of this study are expected to provide clinical evidence regarding the effectiveness of virtual reality-assisted rehabilitation in patients with chronic low back pain and may contribute to the development of evidence-based rehabilitation strategies incorporating digital technologies.",[111],"Chronic Low Back Pain",[111,113,114,115],"Virtual Reality Rehabilitation","Kinesiophobia","Postural Control","2026-04-18",{"date":118,"type":41},"2026-04-22",{"date":120,"type":21},"2026-04-01",{"date":122,"type":21},"2027-05-31",{"name":47,"class":48},{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":11,"sex":16,"minAge":131,"maxAge":57,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":135,"conditions":136,"keywords":138,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":147,"leadSponsor":149,"locationsCount":98},"100628599","evaluation-of-stabilization-training-with-biofeedback-in-lumbosacral-spine-pain-syndrome-100628599","NCT07463729","Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome","Evaluation of the Effectiveness of Stabilization Training With Biofeedback in Patients With Lumbosacral Spine Pain Syndrome","Inclusion Criteria:\n\n* Diagnosed chronic lumbosacral spine pain syndrome (score \\>4 on the Keele STarT Back Screening Tool)\n* Lumbosacral pain intensity \\>3 on the Visual Analog Scale (VAS) persisting for at least the past 3 months\n* Age between 30 and 65 years\n* No concurrent participation in another rehabilitation program\n* Provision of written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Acute phase of lumbosacral spine pain syndrome\n* Presence of neurological symptoms such as paresthesia, dysesthesia, impaired superficial sensation, impaired pain sensation, muscle strength below grade 3 on the Lovett scale in the lower limbs, sphincter dysfunction, or cauda equina syndrome\n* Recent fractures of the spine or pelvis (less than 6 months since injury)\n* Segmental instability confirmed by functional X-ray or magnetic resonance imaging (MRI)\n* Spondylolisthesis greater than Grade I according to the Meyerding classification\n* Coexisting neurological (e.g., Parkinson's disease, neuropathies), autoimmune (e.g., ankylosing spondylitis), orthopedic (lower limb disorders), or oncological diseases\n* Pregnancy\n* Active use of analgesic or anti-inflammatory pharmacotherapy (e.g., steroids, NSAIDs)\n* Concurrent participation in other rehabilitation programs or failure to complete the 8-week therapy program\n* Completion of any structured rehabilitation program within the past 3 months\n* Lack of informed consent to participate in the study","30 Years",{"count":133,"type":21},110,[24],"The aim of the study is to evaluate the effects of biofeedback-assisted stabilization training and conventional therapy on pain perception, balance, spinal mobility, functional performance, physical activity, stress level, and quality of life in patients with lumbosacral spine pain syndrome treated conservatively. The main research questions the study seeks to answer are as follows: Whether and to what extent the implemented therapeutic program improves balance, spinal mobility, functional performance, physical activity, quality of life, and reduces pain perception and stress levels in patients with lumbosacral spine pain syndrome? Are there differences in therapeutic outcomes depending on the treatment method applied? Are the therapeutic effects maintained three months after completion of the intervention? Researchers will compare two groups: a control group and an experimental group. In the control group, stabilization training will be performed without the use of biofeedback. Participants will undergo clinical and functional assessments (Visual Analogue Scale, Oswestry Disability Index, force platform measurements, etc.). Depending on the group to which participants are randomly assigned, participants will participate in manual therapy, stabilization training, and selected physical therapy modalities. Participants will be continuously supervised by a physician and physiotherapists throughout the 8-week intervention period. Three months after completion of the intervention, participants will undergo a follow-up assessment.",[137,111],"Low Back Pain",[139,140,141,142,143],"Chronic low back pain","RUSI","UltrasoundBiofeedback","StabilizationExercises","LumbarStabilization",{"date":145,"type":41},"2026-04-07",{"date":120,"type":41},{"date":148,"type":21},"2027-06-30",{"name":47,"class":48},{"id":151,"slug":152,"hasResults":11,"nctId":153,"briefTitle":154,"officialTitle":155,"acronym":4,"eligibilityCriteria":156,"healthyVolunteers":157,"sex":16,"minAge":158,"maxAge":159,"enrollmentInfo":160,"targetDuration":4,"studyType":22,"phases":162,"briefSummary":163,"conditions":164,"keywords":165,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":98},"100627564","rehabilitation-of-upper-limbs-after-stroke-100627564","NCT07450274","Rehabilitation of Upper Limbs After Stroke","Evaluation of the Effects of Upper Limb Rehabilitation Using the Pablo Tyromotion Device in People After Stroke","Inclusion Criteria:\n\n* informed, voluntary consent of the patient\n* age 45-80 years\n* elementary (basic) gripping ability\n* degree of paresis of the upper limb and hand 4 -5 on the Brunnström scale\n* degree of disability on the Rankin scale 3\n* spastic tension of the upper limb, paresis hand not more than 3 on the modified Ashworth scale\n* current health condition confirmed by a medical examination, allowing participation in tests and exercises\n\nExclusion Criteria:\n\n* lack of informed, voluntary consent of the patient\n* second or subsequent stroke, hemorrhagic stroke, stroke of the brainstem and cerebellum\n* disorders of higher mental functions limiting comprehension and carrying out tasks during exercises\n* visual field disturbances\n* mechanical and thermal injuries that may limit the grasping function of the hand\n* concomitant neurological, rheumatological and orthopedic diseases, including permanent - contractures that may affect the grasping ability and locomotion\n* unstable medical condition\n* failure to complete a 3-week rehabilitation stay",true,"45 Years","80 Years",{"count":161,"type":21},120,[24],"The aim of the research will be to evaluate the effects of upper limb rehabilitation using modern Pablo Tyromotion technologies in people after stroke in the late period.",[65,88],[166,167,168,169,170],"upper limb","hand","rehabilitation","biofeedback","modern technologies","2026-03-12",{"date":173,"type":41},"2026-03-13",{"date":175,"type":41},"2026-03-02",{"date":177,"type":21},"2026-09-30",{"name":47,"class":48},{"id":180,"slug":181,"hasResults":11,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":4,"eligibilityCriteria":185,"healthyVolunteers":157,"sex":16,"minAge":158,"maxAge":159,"enrollmentInfo":186,"targetDuration":4,"studyType":22,"phases":187,"briefSummary":188,"conditions":189,"keywords":190,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":202,"locationsCount":98},"100618550","rehabilitation-with-biofeedback-for-people-after-stroke-100618550","NCT07333079","Rehabilitation With Biofeedback for People After Stroke","Evaluation of the Effectiveness of Biofeedback Rehabilitation in People After Stroke","Inclusion Criteria:\n\n* informed, voluntary consent of the patient\n* age 45-80 years\n* elementary (basic) gripping ability\n* degree of paresis of the upper limb and hand 4 -5 on the Brunnström scale\n* degree of disability on the Rankin scale 3\n* spastic tension of the upper limb, paresis hand not more than 3 on the modified Ashworth scale - current health condition confirmed by a medical examination, allowing participation in tests and exercises\n\nExclusion Criteria:\n\n* lack of informed, voluntary consent of the patient\n* second or subsequent stroke, hemorrhagic stroke, stroke of the brainstem and cerebellum\n* disorders of higher mental functions limiting comprehension and carrying out tasks during exercises\n* visual field disturbances\n* mechanical and thermal injuries that may limit the grasping function of the hand\n* concomitant neurological, rheumatological and orthopedic diseases, including permanent - contractures that may affect the grasping ability and locomotion\n* unstable medical condition\n* failure to complete a 3-week rehabilitation stay",{"count":161,"type":21},[24],"The aim of the research will be to evaluate rehabilitation using the biofeedback method in people after stroke.",[65,88],[65,191,192,193,194,195],"Late period in stroke","Health-resort based rehabilitation","Conventional (traditional) rehabilitation","Modern technologies","Biofeedback","2026-02-23",{"date":198,"type":41},"2026-02-25",{"date":200,"type":41},"2026-01-19",{"date":177,"type":21},{"name":47,"class":48},""]