[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Southern Queensland\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":100},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100617036","self-management-interventions-to-reduce-cardiovascular-risks-in-breast-cancer-survivors-100617036",false,"NCT07313397","Self-management Interventions to Reduce Cardiovascular Risks in Breast Cancer Survivors","Nurse-led and GP-supported Self-management Interventions to Reduce Cardiovascular Risks in Breast Cancer Survivors With Cardiovascular Diseases","Inclusion Criteria:\n\n* aged 18 years or older\n* confirmed diagnosis of breast cancer at stage I, II, or IIIa\n* confirmed diagnosis of CVDs, such as heart failure, hypertension, coronary artery disease, cerebrovascular accidents (e.g., stroke, transient ischemic attack), cardiomyopathy and arrhythmias.\n* able to read, write, and communicate in English\n* have completed active anticancer treatment including chemotherapy and radiotherapy, and are receiving regular healthcare in a primary care centre from GP\u002Fpractice nurses and are willing to participate in the research study and provide informed consent.\n\nExclusion Criteria:\n\n* patients with unstable health conditions with mental health issues or critically ill patients unable to participate in physical activities (e.g., suffering from life-threatening diseases, extremely weak), cognitive impairment, currently involved in another research study, or scheduled anticancer treatment during the study period.","FEMALE","18 Years",{"count":19,"type":20},15,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this proposed single-group pre-post pilot study is to assess the feasibility and acceptability of the codesigned Nurse-led and GP-supported self-management interventions (NGPS) to reduce cardiovascular risks in breast cancer survivors with cardiovascular diseases. The study will also assess the preliminary effects of the NGPS intervention on various outcomes, such as behavioural, physiological, psychological, and healthcare usage. These outcomes will be measured at three time points, which include the baseline measurement at recruitment (T1-week 1), right after the four weeks' intervention (T2-week 4), and eight weeks after completing the intervention (T3-week 12). The study will be conducted in the primary care centres, and the self-management interventions are behavioural change interventions such as physical activity, diet modifications, tobacco cessation, weight management, eliminating or reducing alcohol consumption, and mind-body exercises such as yoga. The main questions it aims to answer are:\n\n1. What are the recruitment, retention, attrition, and completion rates of participants and potential adverse effects related to the NGPS interventions for the participants throughout the pilot study?\n2. What are the adherence rates of the NGPS protocol, participants' response and completion rates of the study instruments during the data collection period of the pilot study?\n3. Do this pilot study results indicate any significant differences in cardiovascular health outcomes (e.g., BMI and blood pressure), physical activity, dietary intake, QoL, self-efficacy, anxiety and depression between and across different time points (Baseline (T1), post-intervention (T2), follow-up (T3))?",[26],"Breast Cancer",[26,28,29,30],"Cardiovascular disease","Self-management Interventions","Breast Cancer Suvivors","NOT_YET_RECRUITING","2026-05-17",{"date":34,"type":35},"2026-05-19","ACTUAL",{"date":37,"type":20},"2026-10",{"date":39,"type":20},"2027-02",{"name":41,"class":42},"University of Southern Queensland","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},"100633123","baduanjin-exercise-on-upper-limb-dysfunction-among-breast-cancer-survivors-100633123","NCT07522593","Baduanjin Exercise on Upper Limb Dysfunction Among Breast Cancer Survivors","Feasibility and Preliminary Evaluation of an Evidence-based Baduanjin Exercise Program for Upper Limb Dysfunction in Breast Cancer Survivors: A Pilot Randomised Controlled Trial","Inclusion Criteria:\n\n1. Female, aged ≥ 18 years, diagnosed with non-metastatic unilateral Stage I-IIIa non-metastatic breast cancer, regardless of cancer type;\n2. Surgeries completed at least two months before enrolment, and completion of radiotherapy and\u002For chemotherapy, with or without aromatase inhibitor therapy, upon enrolment;\n3. Experiencing breast cancer treatment-related ULD, which is measured by the Disabilities of the Arm, Shoulder, and Hand (DASH) scale with a score of 20 or above;\n4. Karnofsky Performance Status Scale (KPS), used to measure a patient's ability to perform daily activities and self-care independently, with a score of 90 or above;\n5. Ability to read, write, and communicate in Chinese;\n6. Have a personal cellphone;\n7. Agree to participate in this study and provide written informed consent.\n\nExclusion Criteria:\n\n1. Any patient with a history of upper limb surgery, injury (fracture or shoulder dislocation), or other conditions not related to breast cancer treatments;\n2. With other complications or adverse medical conditions that cannot perform BdjE, such as severe lymphedema, axillary web syndrome, or adhesive capsulitis;\n3. Undergoing any physiotherapy for ULD or leading regular physical exercises in the previous three months;\n4. Had skin grafting and autologous myocutaneous flap breast reconstruction;\n5. Current clinical diagnosis of depression or anxiety, or receipt of active psychological treatment for significant mood or anxiety disorders;\n6. Currently involved in other clinical studies.",{"count":51,"type":20},76,[23],"The goal of this clinical trial is to learn if Baduanjin exercise could be adopted by breast cancer survivors and improve their upper limb dysfunction. The main questions it aims to answer are:\n\n* Does Baduanjin exercise improve upper limb dysfunction among breast cancer survivors?\n* What problems or adverse events do participants have if they adopt Baduanjin exercise to improve upper limb dysfunction?\n\nParticipants will:\n\n* Adopt Baduanjin exercise following an evidence-based intervention protocol\n* Report their exercise frequency, length, and unexpected symptoms\n* Receive three times assessment and follow-up every week",[55],"Breast Cancer Survivor",[57,58,59,60],"breast cancer survivors","Baduanjin exercise","pilot study","randomised control trail","2026-04-07",{"date":63,"type":35},"2026-04-13",{"date":65,"type":20},"2026-04-20",{"date":67,"type":20},"2027-04",{"name":41,"class":42},1,{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":17,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},"100594038","assessment-of-whether-telehealth-family-psychoeducation-for-major-depressive-disorder-is-doable-100594038","NCT07014241","Assessment of Whether Telehealth Family Psychoeducation for Major Depressive Disorder is Doable","Feasibility Study of Telehealth Family Psychoeducation for Major Depressive Disorder","SPARKED","Inclusion Criteria:\n\n* An individual (aged 18 years or older) with a diagnosis of MDD who has a prescription for at least one antidepressant medication for treating MDD\n* The individual has a family member, family caregiver, or significant other (aged 18 years or older) who plays a role in supporting the individual at home\n* Both the individual with MDD and their support person have basic English language skills, enabling them to engage in family psychoeducational sessions and respond to self-report outcome measures.\n* Both the individual with MDD and their support person voluntarily consent to participate in the study.\n\nExclusion Criteria:\n\n* An individual (aged 18 years or older) who does not have a prescription for at least one antidepressant medication for treating MDD\n* An individual (aged 18 years or older) with MDD whose family member, caregiver, or significant other could not participate in the study\n* An individual (aged 18 years or older) with MDD who has high or imminent suicide risk\n* An individual with MDD who has other serious mental or physical illnesses, cognitive impairment, or hearing impairment without a hearing aid\n* A family member, caregiver, or significant other to an individual with MDD who does not consent to participate in the study",true,"ALL",{"count":81,"type":20},26,[23],"The goal of this single-arm interventional study is to assess the feasibility and acceptability of co-designed telehealth family psychoeducation (FPE) among individuals with major depressive disorder (MDD) and families. The study will also assess the intervention's preliminary impact on personal recovery, antidepressant medication adherence, depression severity, and medication necessity beliefs and concerns. The main questions it aims to answer are:\n\n* What are patients', families', and mental health professionals' views about telehealth FPE for MDD?\n* What are the feasibility and acceptability of telehealth FPE for MDD among individuals with MDD and their families?\n* What is the preliminary impact of telehealth FPE for MDD on personal recovery, antidepressant medication adherence, depression severity, and medication necessity beliefs and concerns?\n\nStudy participants will include individuals with MDD who have prescriptions for antidepressant medications and their family members. Participants will receive three biweekly FPE sessions and a six-week follow-up session via telehealth using a single-family format. The study intervention, telehealth family psychoeducation for MDD, will cover structured modules to enhance participants' understanding of MDD and its treatment, coping strategies, and self-efficacy skills. It will also focus on recognising early signs of relapse and empowering participants to engage in treatment decision-making actively. Hence, the study intervention is termed the Supportive Program for Advancing Recovery, Knowledge, and Empowerment in Depression (SPARKED).\n\nAt baseline, post-intervention, and follow-up, participants with MDD will complete self-reported measures for personal recovery, antidepressant medication adherence, depression severity, and medication necessity beliefs and concerns. In contrast, their family members or caregivers will complete only an outcome measure for medication necessity beliefs and concerns.",[85],"Major Depressive Disorder (MDD)",[87,88,89,90],"Family psychoeducation","Major depressive disorder","Telehealth","Feasibility study","2025-06-08",{"date":93,"type":35},"2025-06-10",{"date":95,"type":20},"2025-11",{"date":97,"type":20},"2026-06",{"name":41,"class":42},2,""]