[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Tromso\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":180},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,45,74,106,147],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100591775","evaluation-of-the-invest-in-play-program---a-new-parent-intervention-for-children-with-problem-behavior-100591775",false,"NCT06984809","Evaluation of the Invest in Play Program - a New Parent Intervention for Children With Problem Behavior","Inclusion Criteria:\n\n* Parents of children between 6-12 years of age referred to out-patient clinics for treatment of behavioural problems.\n* Children scoring above a pre-defined mean cut off score (over the 90 percentile) on the Eyberg Child Behavior Inventory (ECBI; Eyberg \\& Ross, 1978) based on Norwegian norms (Reedtz et al., 2008), as reported by parents.\n\nExclusion Criteria:\n\n\\- Severe developmental delay (in children or parents), autism spectrum disorder, inability to understand Norwegian, or other reasons why the parent(s) are not expected to benefit from group therapy.","ALL","18 Years",{"count":18,"type":19},180,"ESTIMATED","INTERVENTIONAL",[22],"NA","The goal of this clinical trial is to test if the invest in Play (iiP) parent program can reduce problem behaviors in children and improve parenting practices in families with children who show challenging behaviors. The main questions it aims to answer is:\n\n• Does the iiP program reduce children's problem behaviors?\n\nResearchers will compare families in the iiP program to families in a control group to see if the program leads to better outcomes for children and parents.\n\nParticipants will be randomly assigned to either the iiP program group or the control group and complete surveys before and after the program to see if iiP is reducing children's problem behaviors.",[25,26],"Problem Behavior","Attention Deficit and Disruptive Behavior Disorders",[28,29,30,31,32],"parent intervention","parent practices","emotion regulation","parent-child relationship","parental attributions","RECRUITING","2026-06-26",{"date":36,"type":37},"2026-06-29","ACTUAL",{"date":39,"type":37},"2025-09-25",{"date":41,"type":19},"2028-12",{"name":43,"class":44},"University of Tromso","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":53,"minAge":16,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},"100500337","optimizing-mastitis-identification-and-treatment-100500337","NCT05794945","Optimizing Mastitis Identification and Treatment","OPTIMISTOptimizing Mastitis Identification and Treatment","OPTIMIST","Inclusion Criteria:\n\n* Pregnant mothers aged \\> 18\n* mothers must understand information given in Norwegian or English\n* participants must be willing to complete study questionnaires\n* participants must be willing to and provide biological samples\n\nExclusion Criteria:\n\n* No exclusion criteria","FEMALE","50 Years",{"count":56,"type":19},300,"OBSERVATIONAL","The goal of this observational study is to gain more information about the aetiology and progression of mastitis and breast inflammation, in order to develop evidence-based clinical guidelines and treatment plans, especially concerning judicious use of antibiotics.\n\nThe main questions it aims to answer are:\n\n* Do clinical symptoms differ between inflammatory and infectious mastitis?\n* What is the microbial composition in human milk, and does it change before, during, and after episodes of mastitis?\n* Does the bacterial composition change due to antibiotic treatment?\n* Are all mastitis episodes treated with antibiotics bacterial mastitis?\n* Do mothers with recurrent mastitis have a distinct microbial composition?\n* Are there immunological markers that can differentiate between bacterial and inflammatory mastitis?\n\nResearchers will compare breastfeeding women with and without mastitis to see if the microbiological composition in milk and on the skin of the breast and breast nipple differs.",[60],"Mastitis Postpartum",[62,63,64],"Breast inflammation","Clinical mastitis","Sub-clinical mastitis","2026-03-11",{"date":67,"type":37},"2026-03-12",{"date":69,"type":37},"2023-10-01",{"date":71,"type":19},"2028-10-01",{"name":43,"class":44},2,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":15,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":20,"phases":86,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},"100602219","vacuum-massage-vs-tactile-massage-for-the-treatment-of-chronic-neck-pain-100602219","NCT07120659","Vacuum Massage vs Tactile Massage for the Treatment of Chronic Neck Pain","Vacuum Massage vs Tactile Massage for the Treatment of Chronic Neck Pain: A Randomized Controlled Pilot Study Investigating Pain Mechanisms.","MeCNeck","Inclusion Criteria:\n\n* suffer from non-specific neck pain persisting at least 3 months\n* mean pain intensity ≥ 50 on a 0-100 mm visual analogue scale (NRS) with \"0\" meaning \"no pain\" and \"100\" meaning \"worst pain imaginable\"\n\nExclusion Criteria:\n\n* neurological symptoms\n* having had a vertebral column surgery less than 12 months prior to the study,\n* have received TENS, acupuncture, osteopathy, or a chiropractic maneuver or infiltration at the area within 4 weeks prior to the inclusion in the study\n* suffer from a congenital deformation of the spine.","21 Years","75 Years",{"count":85,"type":19},60,[22],"Chronic pain significantly impacts individuals and society, with about 30% of Norwegian adults affected, making it the leading cause of long-term sick leave and disability benefits. Concerns over addiction to pain medications highlight the need for non-pharmacological treatments, though many such therapies, often complementary or alternative, are not widely available in conventional healthcare. Unclear biomechanisms of these therapies pose challenges for clinical trials and acceptance.\n\nThis pilot study aims to explore the effects of two types of massage-cupping massage (CM, intense) and tactile massage (TM, soft)-on chronic neck pain, focusing on their mechanisms of action. Quantitative sensory testing (QST) will be used as a biomarker to assess changes in the pain pathway. A previous feasibility study on CM and QST conducted in Germany informs this research.\n\nThe study will recruit 60 patients with chronic neck pain, randomized to CM or TM, with six weekly treatment sessions. QST will be measured before and after treatment to understand therapy-induced changes in the pain pathway. Findings will help tailor massage therapies to individual needs, improve clinical trial quality, and promote the integration of non-pharmacological treatments into conventional care, benefiting a large population in need.",[89],"Chronic Neck Pain",[91,92,93,94,95,96],"chronic neck pain","massage","soft touch massage","vacuum massage","cupping","quantitative sensory testing QST","2025-12-10",{"date":99,"type":37},"2025-12-11",{"date":101,"type":37},"2025-10-27",{"date":103,"type":19},"2030-12-31",{"name":43,"class":44},1,{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":114,"enrollmentInfo":115,"targetDuration":4,"studyType":20,"phases":117,"briefSummary":118,"conditions":119,"keywords":123,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":105},"100587004","fibromyalgia-somatic-tracking-and-exercise-program-study-100587004","NCT06922747","FIBROmyalgia: Somatic Tracking and Exercise Program Study","FIBROSTEPS Protocol: A 2×2 Factorial Randomized Controlled Trial Evaluating Group Exercise and Somatic Tracking in Fibromyalgia","FIBROSTEPS","Inclusion Criteria:\n\n* Diagnosed with fibromyalgia according to the criteria specified in Wolfe et al (2016)\n* Able to perform light physical activity\n* Able to provide written informed consent\n* Owning a smartphone\n* Able to be followed for 24 weeks\n\nExclusion Criteria:\n\n* Pregnant\n* Severe co-morbid psychiatric or neurological disorders\n* Current participation in another clinical trial\n* Recent surgery or other physical constraints preventing exercise","65 Years",{"count":116,"type":19},200,[22],"The goal of this clinical trial is to learn if the combination of two interventions is more effective in treating fibromyalgia symptoms than one intervention alone. The participant group will be people with fibromyalgia in age group 18-65 years. The two interventions to be tested over sixteen weeks are:\n\n* weekly exercise sessions in groups\n* weekly consultations with a therapist\n\nThe main question it aims to answer is: Is the combination of group exercising and somatic tracking work more efficient than physical activity alone in terms of managing fibromyalgia?\n\nParticipants will wear Fitbit activity trackers, register pain intensity daily on a mobile app, and answer the Fibromyalgia Impact Questionnaire (FIQ). They will be divided into four groups:\n\n* one group receiving the exercise intervention\n* one group receiving the psychological intervention\n* one group receiving both intervention\n* one control group recieving general physical activity recommendations\n\nBefore the sixteen weeks intervention period, there will be a baseline period of eight weeks. Durng the baseline period, participants will wear activity trackers and maintain their usual lifestyle.\n\nResearchers will compare the combination of the interventions against only one intervention and the control group.",[120,121,122],"Fibromyalgia (FM)","Fibromyalgia","Fibromyalgia Syndrome",[124,125,126,127,128,129,130,131,132,133,134,135,136,137],"fibromyalgia impact questionnaire","randomized controlled trial","clinical trial","factorial design","2*2 factorial design","physical activity","somatic tracking","activity","fibromyalgia","pain","effect study","musculoskeletal pain","rheumatic diseases","musculoskeletal diseases","NOT_YET_RECRUITING","2025-05-07",{"date":141,"type":37},"2025-05-13",{"date":143,"type":19},"2027-01",{"date":145,"type":19},"2028-01",{"name":43,"class":44},{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":153,"eligibilityCriteria":154,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":83,"enrollmentInfo":155,"targetDuration":4,"studyType":20,"phases":157,"briefSummary":158,"conditions":159,"keywords":163,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":105},"100543128","sleep-well-despite-persistent-pain-symptoms-100543128","NCT06351839","Sleep Well Despite Persistent Pain Symptoms","Metacognitive Behavioral Therapy Integrated in Sleep Treatment for Comorbid Insomnia in Patients With Persistent Pain: A Randomized Controlled Semi-Crossover Clinical Trial","Sleep-Well","Inclusion Criteria:\n\n* Patients who, after clinical examination at University hospital of Northern Norway (UNN) fill the criteria for a chronic non-malignant pain diagnosis according to ICD-10.\n* Satisfy criteria for a comorbid insomnia\n* Both first-time referrals and former referred patients.\n\nExclusion Criteria:\n\n* A comorbid drug abuse diagnosis (ICD-10)\n* An ongoing compensation and\u002For insurance case related to a health issue, illness or treatment\n* Drug treatment using \\>100 morphine equivalents\n* Participation in other group-based treatments at the UNN Pain Department or the Physical Outpatient Medical Clinic (must be completed before inclusion)",{"count":156,"type":19},106,[22],"Background: The prevalence of comorbid insomnia is 8-10 times higher in patients with chronic pain than in the general population. Insomnia adds a considerable burden as it worsens the quality of life, restoration and repair, mental health and pain symptoms. Since pain and sleep problems are mutually reinforcing, improvements in sleep may have beneficial effects on pain. Unfortunately, the customary use of sleep medication (TAU: treatment-as-usual) often yields short-lived plus side effects. The \"Sleep-Well\" intervention examines if a group-based intervention program focusing on sleep literacy, sleep restriction, stimulus control and metacognitive therapy modules may perform better than TAU in improving patients' insomnia and sleep quality.\n\nEligible patients: Investigators target adult patients referred to the University Hospital of North Norway (Tromsø) for a diagnostic evaluation of their pain condition. Patients eligible for the Sleep-Well study are those who satisfy diagnostic criteria for a non-malign pain disorder plus a comorbid insomnia sleep disorder. Patients are not eligible if they use drugs or large doses of morphine (\\>100 equivalents), are engaged in an insurance case due to their diagnosis, or participate in other ongoing group programs at the hospital.\n\nAims: This trial uses a randomized semi-crossover design to examine if the Sleep-Well group does better regarding insomnia and sleep quality than the control patients (TAU). The primary outcome measures are reductions in diagnostic criteria for insomnia, self-reported insomnia symptoms, quality of life, and actigraphy-measured insomnia indicators (long sleep onset latency, frequent nightly awakenings and early morning awakening). The secondary outcome measures include a simplified polysomnography measurement of brain activity during sleep to assess if proportions or durations of slow-wave versus light-wave sleep and EEG-based arousal indices improve. In addition, it is examined if the Sleep-Well intervention incurs benefits concerning pain complaints, dysfunctional sleep and pain cognitions, anxiety and depression.\n\nThe intervention: The Sleep-Well program schedules group sessions that cover four topics (sleep literacy, behavioural and mental strategies, maintenance and relapse prevention). All sessions are led by two therapists. Those randomized to the active control group (TAU) cross over to the Sleep-Well intervention three months later.",[160,161,162],"Insomnia Chronic","Insomnia Due to Medical Condition","Pain, Chronic",[164,165,166,167,168,169,170,171],"Insomnia","Comorbid insomnia","Chronic pain","MetaCognitive Therapy for Insomnia","Sleep Hygiene","Sleep Education","Sleep Restriction","Group therapy","2025-02-21",{"date":174,"type":37},"2025-02-24",{"date":176,"type":37},"2025-01-01",{"date":178,"type":19},"2027-12",{"name":43,"class":44},""]