[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Twente\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":160},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,79,110,134],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100641925","an-online-lifestyle-program-with-an-ai-lifestyle-coach-and-continues-glucose-monitoring-in-type-2-diabetes-100641925",false,"NCT07661381","An Online Lifestyle Program With an AI Lifestyle Coach and Continues Glucose Monitoring in Type 2 Diabetes.","\"An Online Personalised Lifestyle Program With a Virtual AI Lifestyle Coach in Combination With Continues Glucose Monitoring for People With Type 2 Diabetes.\"","PREVAIL","Inclusion Criteria:\n\n* Age: ≥18 years\n* HbA1c: ≥53 mmol\u002Fmol (7 - 12%)\n* Signed informed consent form and willing to comply with the study procedures\n* Persons who are naïve for participation in a lifestyle program for the past two years\n* Being digitally competent\n* Mastering the Dutch language\n* Accepting the confidential use and storage of anonymised data for analysis and publication (at least 15 years)\n\nExclusion Criteria:\n\n* Medication use: any other glucose-lowering medication than metformin\n* Comorbidities or medical conditions requiring a special diet that conflicts with the study\n* Unstable body weight in the three months prior to inclusion in the study (±5% change based on body weight)\n* Circumstances that lead to unreliable HbA1c values, such as blood donation\n* Pregnant or lactating women","ALL","18 Years",{"count":20,"type":21},160,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of this study is to evaluate the feasibility and effectiveness of a remote personalised lifestyle program in individuals with T2D. Outcomes will be assessed at the start and after 3, 6, and 12 months with two follow-up measurements (18 and 24 months) to determine whether participation in this re-mote lifestyle program leads to improvements in health and diabetes-related outcomes.",[27],"Diabetes Type 2",[29,30,31,32,33,34],"Lifestyle intervention","Artificial intelligence","Remote study","Dietary intake","Continuous glucose monitoring","Lifestyle coach","NOT_YET_RECRUITING","2026-06-22",{"date":38,"type":39},"2026-06-25","ACTUAL",{"date":41,"type":21},"2026-09",{"date":43,"type":21},"2028-12",{"name":45,"class":46},"University of Twente","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":47},"100640718","quantifying-blood-flow-in-the-aorta-100640718","NCT07577752","Quantifying Blood Flow in the Aorta","Quantifying Blood Flow in the Aorta Using Phase-Contrast 4D Flow MRI - Phase 2","AF-4DMRI-P2","Inclusion Criteria:\n\n* Healthy (in particular without any cardiovascular disease or history thereof) men or women\n* 18 years of age or above;\n* BMI ≤ 30;\n* Willingness to undergo MRI scans;\n* Able to provide signed informed consent (IC)\n\nExclusion Criteria:\n\n* Irregular heartbeat.;\n* Any history of cardiovascular disease or current cardiovascular disease;\n* The standard MRI exclusion criteria (such as pacemakers, cerebral vascular clips, pregnancy, claustrophobia)",true,"85 Years",{"count":59,"type":21},70,"OBSERVATIONAL","This study aims to gain insights into aortic blood flow in healthy volunteers using PC 4D-flow MRI",[63],"Healthy Aortic Blood Flow",[65,66,67,68,69],"Blood flow","Aorta","Magnetic Resonance Imaging","PC 4D-flow MRI","MRI","RECRUITING","2026-05-04",{"date":73,"type":39},"2026-05-11",{"date":75,"type":21},"2026-06-01",{"date":77,"type":21},"2027-07-31",{"name":45,"class":46},{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":17,"minAge":87,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":90,"conditions":91,"keywords":95,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},"100629483","svf-treo-study-influence-of-cardiac-and-respiratory-pulsatility-deformation-100629483","NCT07475260","SVF-Treo Study: Influence of Cardiac and Respiratory Pulsatility Deformation","Investigating the Influence of Cardiac and Respiratory Pulsatility Deformation on the Abdominal Aorta Before and After the Implantation of the Fenestrated TREO.","SVF-Treo","Inclusion Criteria:\n\n* Asymptomatic AAA,\n* Age \\> 65\n* Indication for AAA treatment according to standard practice\n* Anatomic suitability for the fenestrated Treo stent graft\n* At least one stentable main renal artery and one other stentable renal or mesenteric artery\n* Being able to hold their breath for 10 seconds.\n\nExclusion Criteria:\n\n* No informed consent obtained\n* eGFR \\\u003C 30 ml\u002Fmin\n* Allergy for intra venous contrast fluid.","65 Years",{"count":89,"type":21},25,"This is a national multicenter study with 25 patients with a complex AAA undergoing endovascular repair with the Fenestrated TREO™ stent graft. ECG and respiratory-gated CT scans will be performed pre-operatively, at discharge, after 6 months, and after 12 months follow up. If stent movement is still present in after 12 months, then another scan will be taken at 24 months. To include respiratory gated with the ECG-gated, patients will undergo ECG-gated CT scan during an inspiration breath-hold as well as an expiration breath-hold. This double gated CT scans will allow us to analyse the movement of the stent graft caused by the cardiac cycle and respiratory cycle.\n\nThe duration of this study is 2.5 years.",[92,93,94],"Abdominal Aortic Aneurysm","Endovascular Abdominal Aortic Aneurysm Repair","Fenestrated Endovascular Aortic Repair",[92,96,97,98,99,100],"Endovascular Aneurysm Repair","FEVAR","Computed Tomography Imaging","CT","ECGgated","2026-03-16",{"date":103,"type":39},"2026-03-19",{"date":105,"type":21},"2026-04-01",{"date":107,"type":21},"2028-01-31",{"name":45,"class":46},6,{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":22,"phases":120,"briefSummary":121,"conditions":122,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},"100558308","treatment-of-electroencephalographic-status-epilepticus-after-cardiopulmonary-resuscitation-2-telstar-2-100558308","NCT06549426","Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation-2 (TELSTAR-2)","Treatment of ELectrographic STatus Epilepticus After Cardiopulmonary Resuscitation-2: Multicenter Randomised Clinical Trial and Health Economic Evaluation of Anti-seizure Treatment in Comatose Cardiac Arrest Patients With SE on Continuous EEG","TELSTAR-2","Inclusion Criteria:\n\n1. Coma (Glasgow Coma Scale score ≤ 8) after out of hospital cardiac arrest and resuscitation\n2. Age ≥ 18 years\n3. Continuous EEG with at least eight electrodes started \\\u003C 24h after return of spontaneous circulation (ROSC)\n4. ESE or possible ESE according to the Salzburg and ACNS criteria\n5. Possibility to start treatment within three hours after detection of ESE\n\nExclusion Criteria:\n\n1. Known history of another medical condition with limited life expectancy (\\\u003C six months)\n2. Any progressive brain illness, such as a brain tumor or neurodegenerative disease\n3. Pre-admission Glasgow Outcome Scale score of 3 or lower\n4. Reason other than the neurological condition to withdraw treatment\n5. EEG background activity prior to the emergence of ESE indicative of extensive irreversible anoxic brain injury\n6. Follow-up impossible due to logistic reasons, for example not living in the Netherlands or Belgium",{"count":119,"type":21},150,[24],"The goal of this comparative effectiveness trial is to study electrographic status epilepticus (ESE) treatment in comatose patients after cardiac arrest. The main questions the trial aims to answer are:\n\n* Does ESE treatment improve outcome?\n* What is the impact of ESE treatment on healthcare costs?\n\nParticipants in the the intervention group will receive standard care completed with anti-seizure treatment. The control group will receive standard care without anti-seizure treatment.",[123,124],"Coma","Electrographic Status Epilepticus","2025-05-13",{"date":127,"type":39},"2025-05-16",{"date":129,"type":39},"2025-04-10",{"date":131,"type":21},"2030-12",{"name":45,"class":46},20,{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":142,"targetDuration":4,"studyType":22,"phases":144,"briefSummary":145,"conditions":146,"keywords":150,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":47},"100535202","ppi-and-mindfulness-app-for-parents-of-children-with-a-ndd-100535202","NCT06248762","PPI and Mindfulness App for Parents of Children with a NDD","Effectiveness of a Positive Psychology and Mindfulness Based App for Parents of Children with a Neurodevelopmental Disorder (NDD): Study Protocol of a Pragmatic Randomized Controlled Trial","Adappt","Inclusion Criteria:\n\n1. at least 18 years\n2. parent of one or more children (\\\u003C 18 years) diagnosed with or suspected of a NDD\n3. having access to internet\n4. in possession of an e-mail address,\n5. in possession of a smartphone or tablet\n6. willing to use the digital intervention for a month, daily for approximately 15 minutes a day.\n\nExclusion Criteria:\n\n1. presence of severe anxiety symptoms\n2. presence of moderately severe to severe depressive symptoms\n3. being in treatment for mental health issues (the parent self)",{"count":143,"type":21},212,[24],"An app based on positive psychology and mindfulness to support the mental well-being of parents of children with a Neurodevelopmental Disorder (NDD) was developed and will be evaluated on effectiveness.",[147,148,149],"Stress","Mental Health","Mental Well-being",[151,140],"ability to adapt","2025-02-19",{"date":154,"type":39},"2025-02-21",{"date":156,"type":39},"2024-12-03",{"date":158,"type":21},"2025-08",{"name":45,"class":46},""]