[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Valencia\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":675},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,53,0,25,[9,51,84,115,141,165,195,221,243,260,280,303,331,359,385,417,441,469,496,533,560,585,611,631,652],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100610974","impact-of-abutment-screw-torque-on-marginal-bone-loss-100610974",false,"NCT07234552","Impact of Abutment Screw Torque on Marginal Bone Loss","Impact of Abutment Screw Torque Values on Marginal Bone Loss and Peri-Implant Parameters: A Three-Arm Randomized Clinical Trial","Inclusion Criteria:\n\n* Posterior edentulism\n* Completion of craniofacial growth\n* Full-mouth plaque index and bleeding index \\\u003C 25%\n* Sufficient bone height and width for implant placement without the need for bone regeneration procedures\n* Presence of at least 2 mm of keratinized mucosa around the dental implant\n* Stable occlusion and healthy periodontium\n* Absence of medical conditions that contraindicate implant surgery, such as heavy smoking (\\\u003C10 cigarettes per day), severe bruxism, pregnancy or breastfeeding, bisphosphonate therapy, and patients undergoing chemotherapy or radiotherapy in the head and\u002For neck area\n* Uncooperative patients\n\nExclusion Criteria:\n\n* Loss to follow-up\n* Incorrectly parallelized periapical radiographs",true,"ALL","18 Years",{"count":21,"type":22},30,"ESTIMATED","INTERVENTIONAL",[25],"NA","The objective of this clinical trial is to evaluate the impact of different torque values applied during transmucosal abutment placement in dental implants on marginal bone loss and peri-implant parameters, including the patient's perception of the treatment.\n\nThe main questions the study aims to answer are:\n\n1. Is there any difference in marginal bone loss between abutments torqued at 15 Ncm, 30 Ncm, and submerged implants without immediate transmucosal connection?\n2. Are there differences in microleakage between the different torque levels?\n3. How do these torque values affect peri-implant soft tissues and patient satisfaction?\n4. Does the applied torque influence the patient's quality of life after the prosthetic phase?\n\nEach participant will receive three dental implants during the same surgical procedure. One of the following approaches will be applied to each implant:\n\n1. A transmucosal abutment torqued to 15 Ncm\n2. A transmucosal abutment torqued to 30 Ncm\n3. A healing cap without transmucosal connection (submerged implant)\n\nAfter implant placement, clinical and radiographic assessments will be performed to measure marginal bone loss and peri-implant parameters.",[28,29,30,31],"Soft Tissues According to the Abutment Torque","Microleakage Accordint to the Abutment Torque","PROMS According to the Abutment Torque","Marginal Bone Loss According to the Abutment Torque",[33,34,35,36,37],"Dental implant","Torque","Marginal bone loss","Microleakage","Abutment","RECRUITING","2026-06-30",{"date":41,"type":42},"2026-07-01","ACTUAL",{"date":44,"type":42},"2026-01-01",{"date":46,"type":22},"2027-04",{"name":48,"class":49},"University of Valencia","OTHER",1,{"id":52,"slug":53,"hasResults":12,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":12,"sex":59,"minAge":19,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":23,"phases":63,"briefSummary":64,"conditions":65,"keywords":72,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":50},"100645009","empowerher-hybrid-digital-intervention-for-breast-cancer-survivors-100645009","NCT07676591","EmpowerHer: Hybrid Digital Intervention for Breast Cancer Survivors","EmpowerHer: Protocol for a Multicentre Randomized Controlled Trial Evaluating a Hybrid Digital Exercise and Education Intervention for Breast Cancer Survivors Across Five European Countries","EmpowerHer","Inclusion Criteria:\n\n* Women aged 18-65 years.\n* History of breast cancer.\n* Completed primary treatment (surgery, chemotherapy, and\u002For radiotherapy; adjuvant hormone therapy is permitted).\n* No evidence of active or metastatic disease at enrolment.\n* Able to provide informed consent and communicate in the local language.\n* Own and are able to use a smartphone.\n* Willing to engage in the exercise program.\n\nExclusion Criteria:\n\n* Cognitive impairment preventing safe participation or questionnaire completion.\n* Uncontrolled medical conditions that contraindicate exercise (e.g., unstable cardiac disease).\n* Concurrently enrolled in another structured exercise or survivorship study.\n* Pregnant or breastfeeding.","FEMALE","65 Years",{"count":62,"type":22},147,[25],"The goal of this clinical trial is to learn if a 12-week hybrid exercise and education program (EmpowerHer) works to improve health-related quality of life in breast cancer survivors aged 35 to 65.\n\nThe main questions it aims to answer are:\n\n* Does the EmpowerHer program improve the everyday quality of life of participants?\n* Does the program lower fatigue, anxiety, and depression while raising physical fitness?\n\nResearchers will compare the EmpowerHer program to usual medical care to see if the program works better to help survivors recover.\n\nParticipants will:\n\n* Use a mobile application at home at least twice a week for structured exercise.\n* Read short educational modules on the mobile application about health after cancer.\n* Attend weekly in-person motivational group sessions with a program facilitator.\n* Complete health and physical tests at the start, at 12 weeks, and 3 months later.",[66,67,68,69,70,71],"Breast Cancer","Cancer Survivors","Quality of Life","Exercise Therapy","Social Support","Mobile Applications",[73,69,74,71,70,75,68],"Breast Cancer Survivors","Digital Health","Multicentre Randomized Controlled Trial","NOT_YET_RECRUITING","2026-06-23",{"date":39,"type":42},{"date":80,"type":22},"2027-07-01",{"date":82,"type":22},"2028-06-30",{"name":48,"class":49},{"id":85,"slug":86,"hasResults":12,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":12,"sex":18,"minAge":60,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":23,"phases":95,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":50},"100619620","non-invasive-brain-stimulation-on-functional-capacity-in-prefrail-older-adults-100619620","NCT07346989","Non-invasive Brain Stimulation on Functional Capacity in Prefrail Older Adults","Effectiveness of Non-invasive Brain Stimulation on Functional Capacity in Prefrail Older Adults","NeuroFit","Inclusion Criteria:\n\n* Age between 65 -90 years old\n* Meet 1-2 frailty criteria, according to Fried's Criteria.\n* Ability to understand instructions (Mini-Mental State Examination \\>23 points).\n* Signing of the informed consent.\n\nExclusion Criteria:\n\n* History of stroke within the past 6 months or hospital admission for any reason within the past 3 months.\n* Alterations of the central or peripheral nervous system\n* Alterations of the vestibular system\n* Concomitant diseases\n* Have a neurological pathology, cardiovascular musculoskeletal that contraindicates physical activity\n* Epilepsy or history, medications that lower the seizure threshold\n* Cardiac pacemaker, endocranial and hearing implants\n* History of severe headaches\n* Uncontrolled intracranial or arterial hypertension\n* Heart and\u002For respiratory failure\n* Implanted medication pump\n* Skin lesions (psoriasis, eczema)\n* Serious head surgeries\n* Completing less than 80% of training sessions","90 Years",{"count":94,"type":22},120,[25],"The general objective of this study is to evaluate the effectiveness of non-invasive neuromodulation combined with a therapeutic exercise program on neuroplasticity and, therefore, on variables related to functional capacity and quality of life, in prefrail older adults.",[98],"Prefrail Elderly",[100,101,102,103,104,105,106],"Prefrail","Non-invasive neuromodulation","TMS","TDCS","Virtual running","Functional capacity","Elderly","2026-06-22",{"date":109,"type":42},"2026-06-25",{"date":111,"type":42},"2026-01-15",{"date":113,"type":22},"2028-07",{"name":48,"class":49},{"id":116,"slug":117,"hasResults":12,"nctId":118,"briefTitle":119,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":17,"sex":59,"minAge":122,"maxAge":123,"enrollmentInfo":124,"targetDuration":4,"studyType":23,"phases":126,"briefSummary":127,"conditions":128,"keywords":131,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":135,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":50},"100625189","acute-effects-of-radiofrequency-diathermy-in-postpartum-women-with-diastasis-abdominis-100625189","NCT07419399","Acute Effects of Radiofrequency Diathermy in Postpartum Women With Diastasis Abdominis","RDPP","Inclusion Criteria:\n\n* Age between 20 and 45 years old.\n* BMI between 18.5 and 29.9 kg\u002Fmw.\n* Postpartum period between 6 months and 1 year Additionally, in the group of women with RAD, pathological RAD will be defined as an inter-rectus distance greater than 2.2 cm (measured 3 cm above the navel), according to the criteria of Beer et al. (2009)\n\nExclusion Criteria:\n\n* Previous surgeries involving the abdominal wall.\n* Cesarean deliveries.\n* Women diagnosed with chronic pain","20 Years","45 Years",{"count":125,"type":22},48,[25],"This clinical trial aims to compare the immediate tissue response in postpartum women with and without rectus abdominis diastasis (RAD) after undergoing radiofrequency diathermy (RFD) treatment. The main question it seeks to answer is: Do postpartum women with and without RAD exhibit different acute tissue responses in terms of pressure pain threshold, superficial thermal sensitivity, and tissue elasticity? To determine whether there are differences in these acute tissue responses between the groups, researchers will compare RFD with a sham RFD intervention in postpartum women with and without RAD.\n\nParticipants will receive one session of either RFD or a sham RFD intervention and will complete three assessments: one at baseline and two after the intervention, one immediately afterwards and one 20 minutes afterwards.",[129,130],"Postpartum","Rectus Muscle Diastasis",[132,133,134],"rectus abdominis diastasis","radiofrequency diathermy","postpartum",{"date":109,"type":42},{"date":137,"type":42},"2026-03-30",{"date":139,"type":22},"2029-03-30",{"name":48,"class":49},{"id":142,"slug":143,"hasResults":12,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":148,"enrollmentInfo":149,"targetDuration":4,"studyType":23,"phases":151,"briefSummary":152,"conditions":153,"keywords":155,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":160,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":164,"locationsCount":50},"100572143","transcranial-direct-current-stimulation-on-functionality-and-pain-in-individuals-with-patellar-tendinopathy-100572143","NCT06729437","Transcranial Direct Current Stimulation on Functionality and Pain in Individuals With Patellar Tendinopathy","Effectiveness of Transcranial Direct Current Stimulation on Functionality and Pain in Individuals With Patellar Tendinopathy: Randomized Clinical Trial","Inclusion Criteria:\n\n* Age between 18 and 50 years.\n* Diagnosis of patellar tendinopathy (VISA-P score of 80 or lower).\n* Pain lasting more than 3 months.\n\nExclusion Criteria:\n\n* Previous knee surgery.\n* Corticosteroid injection in the previous 6 weeks.\n* Systemic inflammatory, autoimmune, or rheumatic diseases.\n* Cognitive or behavioural issues that hinder comprehension and adherence to the intervention.\n* Any neurological disease.\n* Neoplastic disease.\n* Subjects presenting contraindications for tDCS (Thair et al., 2017), including: personal and family history of epilepsy, metallic implants in the head, implanted medication pump, pacemaker, recurrent headaches, skin conditions (psoriasis, eczema), or major head surgeries, pregnancy, heart diseases, and various medications (psychotropic or antihistamines).\n* Subjects must not have undergone pharmacological treatment or knee physical rehabilitation programs for a period of 1 year.","50 Years",{"count":150,"type":22},42,[25],"The aim of the present study is to investigate the effectiveness of transcranial direct current stimulation (tDCS) prior to a therapeutic eccentric exercise program on parameters related to pain and functionality in individuals with patellar tendinopathy. For this purpose, participants will be randomly divided into two groups: i) experimental group, receiving tDCS prior to a therapeutic exercise program; and ii) control group, receiving sham tDCS and a therapeutic exercise program. The interventions will last for 8 weeks. Additionally, four assessments will be conducted (baseline, week 4, week 8 and week 12). The variables studied are related to pain, functionality, muscle activity and strength, proprioception, and quality of life.",[154],"Patellar Tendinopathy",[156,157,158,159],"patellar tendinopathy","transcranial direct current stimulation","therapeutic exercise","eccentric exercise",{"date":109,"type":42},{"date":162,"type":42},"2024-07-01",{"date":80,"type":22},{"name":48,"class":49},{"id":166,"slug":167,"hasResults":12,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":12,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":172,"targetDuration":4,"studyType":23,"phases":174,"briefSummary":175,"conditions":176,"keywords":181,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":50},"100642304","intervention-to-reduce-unwanted-loneliness-in-family-caregivers-of-people-with-alzheimer-100642304","NCT07639645","Intervention to Reduce Unwanted Loneliness in Family Caregivers of People With Alzheimer","Multimodal Intervention to Reduce Unwanted Loneliness and Improve the Living With Process Among Family Caregivers of People With Alzheimer's Disease","Inclusion Criteria:\n\n* Family caregivers of people with Alzheimer's disease (AD).\n* Primary family caregivers who live with the person with AD.\n* The person with AD must be enrolled in one of the adult day care centers where the study is conducted.\n* Ability to communicate in Spanish and\u002For Valencian.\n\nExclusion Criteria:\n\n* Presence of moderate or severe cognitive impairment, mental disorder, significant sensory impairment, disabling chronic illness, or any medical condition that contraindicates participation in any of the study activities.\n* Family caregivers of institutionalized individuals.\n* Family caregivers of people with AD who have died.",{"count":173,"type":22},50,[25],"The absence of social relationships negatively affects physical, psychological, and social health. In other words, it alters people's quality of life and makes active aging difficult. The investigators have designed a study to reduce unwanted loneliness and improve the living with process of family caregivers of people with Alzheimer disease through multiple interventions (music therapy, health education)",[177,178,179,180],"Alzheimer Disease (AD)","Unwanted Loneliness","Family Caregivers","Living With Process",[182,183,184,185,186],"unwanted loneliness","living with process","alzheimer disease","family caregiver","multicomponent intervention","2026-06-10",{"date":189,"type":42},"2026-06-15",{"date":191,"type":22},"2026-10",{"date":193,"type":22},"2028-12",{"name":48,"class":49},{"id":196,"slug":197,"hasResults":12,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":60,"enrollmentInfo":202,"targetDuration":4,"studyType":23,"phases":204,"briefSummary":205,"conditions":206,"keywords":208,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":4},"100624057","safety-and-effects-of-high-intensity-blood-flow-restriction-training-in-the-rotator-cuff-100624057","NCT07404683","Safety and Effects of High-Intensity Blood Flow Restriction Training in the Rotator Cuff","Safety, Utility and Effects After 8 Weeks of High-intensity Strength Training With Blood Flow Restriction in the Rotator Cuff","Inclusion Criteria:\n\n* Healthy, untrained adults\n* Age between 18 and 65\n\nExclusion Criteria:\n\n* Current participation in an upper limb strength training program\n* Presence of comorbidities that increase cardiovascular risk (uncontrolled ischemic heart disease, uncontrolled hypertension, diabetes, etc.)\n* Patients with more than one thromboembolism risk factor (obesity, history of thrombosis, prolonged immobilization, recent surgery, use of contraceptives, etc.)\n* Current diagnosis of any pathology affecting the cervical spine, shoulder, and\u002For thoracic spine\n* History of surgery in the last year\n* Use of ergogenic aids or medications that affect muscle metabolism (anabolic steroids, testosterone, creatine, protein supplements, corticosteroids, chronic use of nonsteroidal anti-inflammatory drugs, etc.)",{"count":203,"type":22},60,[25],"This study aims to analyze the effects of an 8-week strength training program combining different exercise intensities and blood flow restriction (BFR) conditions on safety, tolerability, muscle adaptations, and physical performance variables. Three training modalities will be compared: 1) high-intensity exercise with BFR therapy; 2) low-intensity exercise with BFR therapy; and 3) high-intensity exercise without BFR therapy. All groups will perform the same exercise modality, differing only in intensity and the application of BFR.\n\nParticipants will be randomly assigned to one of the three groups and will undergo a 8-week intervention. The variables of interest will be assessed in each group for subsequent analysis and comparison.",[207],"Healthy Adult",[209,210,211,212],"blood flow restriction","exercise","high-intensity","rotator cuff","2026-06-08",{"date":215,"type":42},"2026-06-11",{"date":217,"type":22},"2026-09",{"date":219,"type":22},"2028-06",{"name":48,"class":49},{"id":222,"slug":223,"hasResults":12,"nctId":224,"briefTitle":225,"officialTitle":226,"acronym":4,"eligibilityCriteria":227,"healthyVolunteers":12,"sex":18,"minAge":148,"maxAge":228,"enrollmentInfo":229,"targetDuration":4,"studyType":23,"phases":231,"briefSummary":232,"conditions":233,"keywords":235,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":237,"startDateStruct":238,"completionDateStruct":240,"leadSponsor":242,"locationsCount":50},"100617308","acute-exercise-responses-with-blood-flow-restriction-under-dynamic-pressure-compared-to-fixed-pressure-in-patients-with-severe-gonarthrosis-100617308","NCT07316933","Acute Exercise Responses With Blood Flow Restriction Under Dynamic Pressure Compared to Fixed Pressure in Patients With Severe Gonarthrosis","Acute Responses to Different Blood Flow Restriction Exercise Configurations With Dynamic Pressure Compared to Fixed Pressure in Patients With Severe Gonarthrosis","Inclusion Criteria:\n\n* Age between 50 and 85 years\n* Diagnosis of severe gonarthrosis according to the clinical and radiographic criteria of the American College of Rheumatology guidelines.\n* On the waiting list for unilateral total knee replacement (TKR) surgery\n\nExclusion Criteria:\n\n* Pain in the contralateral leg with an intensity ≥80\u002F100 mm on the visual analog scale (VAS) during daily activities.\n* Previous hip or knee replacement surgery and osteotomy within the last year.\n* Autoimmune arthritis\n* Medical conditions that contraindicate exercise.\n* Participation in exercise programs (\\>2 days\u002Fweek with training at intensities of 10-15 1RM) in the previous six months.\n* History of stroke, brain surgery, major depression, or self-reported cognitive impairment that could affect performance in the study.\n* Cardiovascular, thrombotic, or vascular risk factors (uncontrolled hypertension, peripheral arterial disease, history of deep vein thrombosis or pulmonary embolism, heart failure, severe varicose veins, or uncontrolled anticoagulant therapy).\n* Skin or local alterations at the cuff application site (ulcers, open wounds, infections, lymphedema, or severe edema).\n* Inability to communicate normally or with impaired communication skills.","85 Years",{"count":230,"type":22},45,[25],"This study aims to evaluate the acute effects of blood flow restriction (BFR) training on hypoalgesia and neuromuscular responses in patients with severe gonarthrosis by comparing the application of pressure with a dynamic versus a fixed configuration. There will be six different training conditions with varying levels of blood flow occlusion (%BFR) and percentage of load (%RM): 1) 30% RM and 50% BFR with dynamic pressure; 2) 30% RM and 50% BFR with fixed pressure; 3) 50% RM and 50% BFR with dynamic pressure; 4) 50% RM and 50% BFR with fixed pressure; 5) 30% RM and 80% BFR with dynamic pressure; 6) 30% RM and 80% BFR with fixed pressure.\n\nEach participant will complete six individual sessions under different training conditions, assigned in a random order with a 72-hour interval between each session.",[234],"Severe Knee Osteoarthritis",[209,210,236],"gonarthrosis",{"date":187,"type":42},{"date":239,"type":42},"2026-03-01",{"date":241,"type":22},"2027-12",{"name":48,"class":49},{"id":244,"slug":245,"hasResults":12,"nctId":246,"briefTitle":247,"officialTitle":247,"acronym":4,"eligibilityCriteria":227,"healthyVolunteers":12,"sex":18,"minAge":148,"maxAge":228,"enrollmentInfo":248,"targetDuration":4,"studyType":23,"phases":249,"briefSummary":250,"conditions":251,"keywords":252,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":254,"startDateStruct":255,"completionDateStruct":257,"leadSponsor":258,"locationsCount":259},"100616036","acute-effects-of-blood-flow-restriction-training-to-failure-on-hypoalgesia-in-patients-with-severe-knee-osteoarthritis-using-dynamic-or-fixed-occlusion-pressure-100616036","NCT07300384","Acute Effects of Blood Flow Restriction Training to Failure on Hypoalgesia in Patients With Severe Knee Osteoarthritis Using Dynamic or Fixed Occlusion Pressure",{"count":230,"type":22},[25],"This study aims to compare the acute effects on hypoalgesia of training to failure using blood flow restriction (BFR) with dynamic occlusion versus BFR with fixed occlusion in patients with severe gonarthrosis. Two different training conditions will be performed with varying levels of blood flow occlusion (%BFR) and percentage of load (%RM): 1) 30% RM and 50% BFR with dynamic pressure; 2) 30% RM and 50% BFR with fixed pressure. Each participant will complete two individual sessions under different training conditions, randomly assigned with a 72-hour interval between sessions.",[234],[253,210,236],"bood flow restriction",{"date":187,"type":42},{"date":256,"type":42},"2026-02-25",{"date":241,"type":22},{"name":48,"class":49},2,{"id":261,"slug":262,"hasResults":12,"nctId":263,"briefTitle":264,"officialTitle":265,"acronym":4,"eligibilityCriteria":266,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":60,"enrollmentInfo":267,"targetDuration":4,"studyType":23,"phases":269,"briefSummary":270,"conditions":271,"keywords":273,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":275,"startDateStruct":277,"completionDateStruct":278,"leadSponsor":279,"locationsCount":4},"100617928","effects-of-a-4-week-low-intensity-training-with-blood-flow-restriction-in-people-with-rotator-cuff-related-shoulder-pain-100617928","NCT07324993","Effects of a 4-week Low-intensity Training With Blood Flow Restriction in People With Rotator Cuff-related Shoulder Pain","Analysis of the Effects of a 4-week Low-intensity Training With and Without Blood Flow Restriction in People With Rotator Cuff-related Shoulder Pain","Inclusion Criteria:\n\n* Age between 18 and 65.\n* Shoulder symptoms lasting at least 3 months.\n* Pain in the proximal anterolateral aspect of the shoulder, aggravated by abduction.\n* At least two of the following tests positive: Jobe test, resisted external rotation test, Hawkins-Kennedy test, Neer test, painful arc between 60 and 120 degrees of shoulder abduction.\n\nExclusion Criteria:\n\n* Pain of an intensity that prevents performance of the proposed exercises.\n* Active arm elevation less than 90 degrees.\n* Clinical signs of a complete tear (positive delayed external and internal rotation sign and positive drop arm test).\n* Suspected frozen shoulder (50% reduction or more than 30° loss of passive shoulder external rotation).\n* Primary diagnosis of shoulder instability or acromioclavicular pathology.\n* Shoulder pain due to primary involvement in the cervical or thoracic region\n* Corticosteroid injection within the last 6 weeks.\n* Presence of diseases such as inflammatory arthritis, neurological diseases, fibromyalgia, malignant tumors, or polymyalgia rheumatica.\n* Presence of comorbidities that increase cardiovascular risk, such as hypertension, diabetes, or heart failure.\n* Presence of more than one thromboembolism risk factor (obesity, history of thrombosis, prolonged immobilization, recent surgery, use of contraceptives, etc.).\n* Presence of active skin lesions in the area where the sleeve will be placed, recent scars or burns, or chronic dermatological diseases that compromise skin integrity,\n* Participation in upper limb exercise programs in the last month.",{"count":268,"type":22},34,[25],"This study aims to analyze the effects of 4 weeks of low-intensity exercise with and without blood flow restriction (BFR) on pain, fear of movement, catastrophizing about pain, strength, and disability in a population with rotator cuff-related shoulder pain. There are two modalities corresponding to the same exercises under different blood flow restriction conditions: 1) 3 low-intensity exercises (30% 1RM) with BFR (50% AOP); 2) 3 low-intensity exercises (30% 1RM) without BFR.\n\nParticipants will be randomly assigned to one of two groups and will undergo a 4-week intervention. The variables of interest will be assessed in each group for subsequent analysis and comparison.",[272],"Rotator Cuff Related Shoulder Pain",[209,210,274],"rotator cuff-related shoulder pain",{"date":276,"type":42},"2026-06-09",{"date":217,"type":22},{"date":219,"type":22},{"name":48,"class":49},{"id":281,"slug":282,"hasResults":12,"nctId":283,"briefTitle":284,"officialTitle":285,"acronym":4,"eligibilityCriteria":286,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":287,"enrollmentInfo":288,"targetDuration":4,"studyType":23,"phases":289,"briefSummary":290,"conditions":291,"keywords":294,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":298,"startDateStruct":299,"completionDateStruct":300,"leadSponsor":302,"locationsCount":50},"100600734","acute-effects-of-aerobic-exercise-and-high-intensity-interval-exercise-with-immersive-virtual-reality-100600734","NCT07101341","Acute Effects of Aerobic Exercise and High-intensity Interval Exercise With Immersive Virtual Reality","Analysis of the Acute Effects of Aerobic Exercise and High-intensity Interval Exercise, With and Without the Simultaneous Application of Immersive Virtual Reality","Inclusion Criteria:\n\n* Healthy people between 18 and 35 years old\n\nExclusion Criteria:\n\n* Current or recent injury that affects training\n* Condition that prevents exercise (decompensated heart disease, decompensated respiratory disease, significant mobility difficulties, etc.)\n* Visual problems that prevent exercise with virtual reality headsets","35 Years",{"count":230,"type":22},[25],"This study aims to compare the acute effects at the cardiovascular (heart rate, blood pressure) and physiological (lactate) levels, as well as the perception of effort and fatigue, of four exercise modalities, one based on the traditional aerobic training methodology, another based on high-intensity interval training (HIIT), another consisting of aerobic exercise performed in conjunction with an immersive virtual reality (VR) application, and a last one consisting of exercise with HIIT-type parameters but also performed in conjunction with an immersive VR application.\n\nAll participants will complete one session of each of the four exercise modalities, analyzing the variables studied in each for subsequent analysis and comparison.",[292,293],"Acute Effects of Exercise in Healthy People","Health Adult Subjects",[295,296,297],"virtual reality","immersive virtual reality","exergame",{"date":187,"type":42},{"date":256,"type":42},{"date":301,"type":22},"2027-06",{"name":48,"class":49},{"id":304,"slug":305,"hasResults":12,"nctId":306,"briefTitle":307,"officialTitle":308,"acronym":4,"eligibilityCriteria":309,"healthyVolunteers":12,"sex":59,"minAge":19,"maxAge":123,"enrollmentInfo":310,"targetDuration":4,"studyType":23,"phases":312,"briefSummary":313,"conditions":314,"keywords":319,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":324,"lastUpdatePostDateStruct":325,"startDateStruct":326,"completionDateStruct":328,"leadSponsor":330,"locationsCount":50},"100624727","oral-health-education-for-pregnant-women-100624727","NCT07413393","Oral Health Education for Pregnant Women","Knowledge of Oral Health in Pregnant Women: Effect of a Short Educational Intervention","Inclusion Criteria:\n\n* Women aged 18-45 who have recently given birth to healthy babies, either vaginally or by cesarean section.\n* Ability to understand and speak Spanish.\n\nExclusion Criteria:\n\n* Complications during pregnancy or delivery.\n* Newborns with major birth defects.\n* Participants who do not provide informed consent.",{"count":311,"type":22},300,[25],"The goal of this research is to investigate oral health knowledge in pregnant women receiving care at Hospital La Fe and to see whether a one-time informational intervention improves this knowledge. The main questions this research aims to answer are:\n\nWhat is the level of oral health knowledge among pregnant women attending Hospital La Fe?\n\nDoes a one-time informational intervention, delivered through a printed leaflet, improve oral health knowledge during pregnancy?\n\nWhat factors are related to differences in oral health knowledge among pregnant women?\n\nParticipants are pregnant women receiving care at Hospital La Fe. They will:\n\nComplete a questionnaire about their oral health knowledge.\n\nReceive a printed informational leaflet about oral health during pregnancy.\n\nComplete the same questionnaire again after a period of time to see if their knowledge has changed.\n\nResearchers will compare answers before and after the leaflet is provided to see whether oral health knowledge improves. They will also explore which personal or social factors are linked to different levels of oral health knowledge.",[315,316,317,318],"Knowledge","Oral Health","Pregnant Women","Intervention",[320,321,322,323],"oral health","knowledge","pregnant","improvement","2026-06-05",{"date":276,"type":42},{"date":327,"type":42},"2026-02-15",{"date":329,"type":22},"2026-07-30",{"name":48,"class":49},{"id":332,"slug":333,"hasResults":12,"nctId":334,"briefTitle":335,"officialTitle":336,"acronym":4,"eligibilityCriteria":337,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":338,"targetDuration":4,"studyType":23,"phases":340,"briefSummary":341,"conditions":342,"keywords":346,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":354,"completionDateStruct":356,"leadSponsor":358,"locationsCount":50},"100632099","peri-implant-tissues-changes-for-different-abutment-shapes-and-heights-100632099","NCT07509281","Peri-implant Tissues Changes for Different Abutment Shapes and Heights","Influence of Supracrestal Soft Tissue on Peri-implant Bone Changes for Different Abutment Shapes and Heights: A Four-Arm Randomized Clinical Trial","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Posterior edentulism (premolars\u002Fmolars).\n* Good general and oral health, with controlled plaque and bleeding indices.\n* Sufficient bone height and width for implant placement without the need for bone regeneration procedures. Patients who require indirect sinus lift procedure simultaneously with implant placement may be included in the study.\n* Presence of at least 2 mm of keratinized mucosa around the dental implant.\n* Stable occlusion and healthy periodontium.\n* Insertion torque ≥ 35 Ncm at the time of implant placement.\n* Willingness to comply with study protocol and attend scheduled follow-up visits.\n\nExclusion Criteria:\n\n* Presence of medical conditions that contraindicate implant surgery, such as heavy smoking (\\>10 cigarettes per day), severe bruxism, pregnancy or breastfeeding, bisphosphonate therapy, and patients undergoing chemotherapy or radiotherapy in the head and\u002For neck area.\n* Active periodontal disease or peri-implant infection.\n* Uncooperative patients or patients unable to complete follow- up.\n* Implant failures.",{"count":339,"type":22},180,[25],"The goal of this randomized clinical trial is to investigate the influence of supracrestal soft tissue on abutments of different heights (2-mm vs. 3-mm) and shapes (cylindrical abutment vs. concave abutment) on changes in the marginal bone level (bone loss and bone remodeling) in healthy, partially edentulous volunteer patients undergoing implant-supported rehabilitation.\n\nThe main questions it aims to answer are:\n\n* Is there any difference in marginal bone loss for different abutment shapes and heights?\n* Do the shape and height of the abutment affect implant success?\n\nAll participants will receive bone-level dental implants placed approximately 2-mm below the bone crest, each receiving a different type of abutment and researchers will see whether the shape and height of the abutment influence the success of the implant, periodontal probing depth (PPD), and bleeding on probing (BoP) comparing four groups of patients:\n\n1. 2-mm high abutments with cylindrical shape.\n2. 2-mm high abutments with concave shape.\n3. 3-mm high abutments with cylindrical shape.\n4. 3-mm high abutments with concave shape.\n\nClinical and radiographic assessments will be performed at abutment placement, at definitive prosthesis placement, and at 1, 3, 6, and 12 months after loading to measure marginal bone loss and peri-implant parameters.",[343,344,345],"Dental Implant-Abutment Designs","Marginal Bone Loss in Different Abutment Designs","Soft Tissue Management in Subcrestal Dental Implants",[347,348,349,350,351],"dental implant","implant abutment","marginal bone loss","prostheses abutment width","prostheses abutment height","2026-06-03",{"date":324,"type":42},{"date":355,"type":42},"2026-06-01",{"date":357,"type":22},"2027-09-30",{"name":48,"class":49},{"id":360,"slug":361,"hasResults":12,"nctId":362,"briefTitle":363,"officialTitle":364,"acronym":365,"eligibilityCriteria":366,"healthyVolunteers":17,"sex":18,"minAge":122,"maxAge":367,"enrollmentInfo":368,"targetDuration":4,"studyType":23,"phases":370,"briefSummary":371,"conditions":372,"keywords":374,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":378,"lastUpdatePostDateStruct":379,"startDateStruct":380,"completionDateStruct":382,"leadSponsor":384,"locationsCount":4},"100638859","impact-of-at-home-dental-bleaching-on-quality-of-life-using-ohip-14-100638859","NCT07624344","Impact of At-Home Dental Bleaching on Quality of Life Using OHIP-14","Clinical Evaluation of Color Changes (CIELAB),Whiteness Index (WID), and Oral Health-Related Quality of Life (OHIP-14) Following At-home Dental Bleaching: A Prospective Clinical Study","WID-OHIP","Inclusion Criteria:\n\n* Age between 20 and 40 years\n* Healthy gums and periodontal condition\n* No oral diseases\n* No previous dental bleaching treatment\n* No restorations in anterior teeth\n* Ability to attend follow-up visits\n* Willingness to follow the study instructions\n\nExclusion Criteria:\n\n* Smoking\n* Pregnancy\n* Breastfeeding\n* Medical conditions that could affect bleaching treatment\n* Use of medications that could interfere with bleaching treatment\n* Inability to comply with scheduled appointments","40 Years",{"count":369,"type":22},10,[25],"This prospective clinical study aims to evaluate the clinical efficacy of an at-home dental bleaching protocol and its impact on oral health-related quality of life using objective color measurements and patient-reported outcomes. Changes in tooth color will be assessed using CIELAB parameters (L\\*, a\\*, b\\*) and the Whiteness Index for Dentistry (WID), while quality of life will be evaluated using the OHIP-14 questionnaire.",[373],"Tooyh Discoloration",[375,376,377],"Dental bleaching At-home bleaching Carbamide peroxide WID OHIP-14","CIELAB","Oral health-related quality of life","2026-05-31",{"date":352,"type":42},{"date":381,"type":22},"2026-11-01",{"date":383,"type":22},"2027-07-31",{"name":48,"class":49},{"id":386,"slug":387,"hasResults":12,"nctId":388,"briefTitle":389,"officialTitle":389,"acronym":4,"eligibilityCriteria":390,"healthyVolunteers":17,"sex":18,"minAge":391,"maxAge":392,"enrollmentInfo":393,"targetDuration":4,"studyType":23,"phases":395,"briefSummary":396,"conditions":397,"keywords":400,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":409,"lastUpdatePostDateStruct":410,"startDateStruct":412,"completionDateStruct":414,"leadSponsor":416,"locationsCount":50},"100640147","evaluation-of-materials-for-the-distribution-of-pressure-in-the-treatment-of-neuroischemic-ulcers-100640147","NCT07620379","Evaluation of Materials for the Distribution of Pressure in the Treatment of Neuroischemic Ulcers","Inclusion Criteria:\n\n* Aged between 55 and 75.\n* Diagnosis of diabetes mellitus.\n* Patients with an ankle-brachial index of \\>0.8 and \\\u003C1.2.\n* Signature of the informed consent form\n\nExclusion Criteria:\n\n* Leg or foot injuries or ulcers that cause pain and prevent normal movement in both lower limbs.\n* Foot trauma within the last month.\n* Inability to adhere to the full schedule of measurements required by the study.\n* Participants who do not sign the informed consent form.\n* Known contact dermatitis to any of the study materials","55 Years","75 Years",{"count":394,"type":22},46,[25],"The hypothesis of this study is based on the premise that pressure-distributing materials with superior biomechanical and tissue response properties will be capable of improving the healing rate of neuropathic ulcers.\n\nThe overarching objective of the present project is to assess the influence of the nature and method of application of the materials under study on tissue response, the reduction of pressure on the sole of the foot, and the healing of neuropathic ulcers in patients with diabetes mellitus.",[398,399],"Diabetic Complications","Foot Care",[401,402,403,404,405,406,407,408],"diabetic foot","plantar pressure","offloading","felt padding","hyperspectral imaging","thermography","pressure redistribution","ulcer prevention","2026-05-26",{"date":411,"type":42},"2026-06-02",{"date":413,"type":42},"2021-03-09",{"date":415,"type":22},"2027-03-08",{"name":48,"class":49},{"id":418,"slug":419,"hasResults":12,"nctId":420,"briefTitle":421,"officialTitle":422,"acronym":423,"eligibilityCriteria":424,"healthyVolunteers":12,"sex":59,"minAge":19,"maxAge":60,"enrollmentInfo":425,"targetDuration":427,"studyType":428,"phases":4,"briefSummary":429,"conditions":430,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":433,"lastUpdatePostDateStruct":434,"startDateStruct":436,"completionDateStruct":438,"leadSponsor":440,"locationsCount":259},"100374647","creation-and-validation-of-a-questionnaire-evaluating-diastasis-recti-100374647","NCT04158180","Creation and Validation of a Questionnaire Evaluating Diastasis Recti","Creation and Validation of a Questionnaire on Diastasis Recti Signs and Symptoms","QUEDIA","Inclusion Criteria:\n\n* subjects with diastasis recti,\n* adult,\n* women.\n\nExclusion Criteria:\n\n* cognitive disabilities that can difficult a good understanding of the questionnaire,\n* lack of knowledge of Spanish language.\n* ventral hernia.\n* previous abdominal surgeries.",{"count":426,"type":22},125,"2 Years","OBSERVATIONAL","Introduction. Distasis rectus abdominis (DRA) is defined as the presence of divergence between the rectus abdominis muscles along the linea alba. Some authors describe a prevalence of 40% in women up to one year postpartum. Some studies suggest that the presence of DRA can be related to the appearance of low back, pelvic and abdominal pain and even urinary incontinence. These factors can significantly affect the quality of life of women with diastasis both socially, sexual and personal level. According to several studies, this pathology is related to higher rates of depression and an alteration in the self-perception of body image that makes these women to look to specialized medical care.\n\nAt present, the quantitative evaluation of DRA is performed purely anatomically. This evaluation consists in measuring the separation between the two rectus abdominis. Currently there is no consensus as to the protocol that should be used for this measurement.\n\nSo far, no instrument is able to quantitatively measure the consequences of DRA. The evaluation of symptoms and consequences should include relevant parameters such as quality of life, perception of body image and functional limitations.\n\nThe objective of this study is the creation and validation of a specific questionnaire to evaluate the symptoms and consequences of DRA.\n\nMaterial and methods. A) Development of the questionnaire\n\n1. Literature review\n2. Online survey\n3. Expert panel\n4. Pilot test of the questionnaire\n\nB) Validation of the questionnaire. The psychometric properties of the questionnaire will be evaluated in a sample of patients with DRA. The sample will be composed of a group of adult women with DRA who attended to a physiotherapy clinic.",[431,432],"Diastasis Recti and Weakness of the Linea Alba","Diastasis Recti","2026-05-19",{"date":435,"type":42},"2026-05-22",{"date":437,"type":42},"2021-09-27",{"date":439,"type":22},"2026-11-15",{"name":48,"class":49},{"id":442,"slug":443,"hasResults":12,"nctId":444,"briefTitle":445,"officialTitle":446,"acronym":4,"eligibilityCriteria":447,"healthyVolunteers":17,"sex":59,"minAge":123,"maxAge":228,"enrollmentInfo":448,"targetDuration":4,"studyType":23,"phases":450,"briefSummary":451,"conditions":452,"keywords":457,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":462,"lastUpdatePostDateStruct":463,"startDateStruct":464,"completionDateStruct":466,"leadSponsor":468,"locationsCount":259},"100548359","multimodal-program-for-climacteric-women-100548359","NCT06419972","Multimodal Program for Climacteric Women","Effectiveness of a Combined Education and Exercise Program on the Physical, Functional and Psychological Status of Climacteric Women.","Inclusion Criteria:\n\n* Women aged ≥45 years\n* Women in climacteric period\n\nExclusion Criteria:\n\n* Musculoskeletal, cognitive, infectious, neurological, or cardiorespiratory pathology impairing assessment or program completion.\n* Surgical intervention in lumbopelvic or gynecological region within the last 6 months.\n\nUndergoing oncological treatment.\n\n\\* Also included women with stable hormone replacement therapy for at least the last 6 months.",{"count":449,"type":22},115,[25],"Your study seems to aim at emphasizing the significance of non-pharmacological and non-hormonal approaches in managing menopausal symptoms, particularly focusing on muscle training and education. This holistic approach acknowledges the importance of physical well-being, psychological support, and education to enhance women's quality of life during the menopausal transition.",[453,454,455,456],"Climacteric Syndrome","Postmenopausal Symptoms","Menopause","Perimenopausal Disorder",[458,459,460,461],"perimenopause","climacteric","Postmenopause","women's health","2026-05-15",{"date":433,"type":42},{"date":465,"type":42},"2024-05-30",{"date":467,"type":22},"2026-12-28",{"name":48,"class":49},{"id":470,"slug":471,"hasResults":12,"nctId":472,"briefTitle":473,"officialTitle":474,"acronym":475,"eligibilityCriteria":476,"healthyVolunteers":12,"sex":59,"minAge":19,"maxAge":123,"enrollmentInfo":477,"targetDuration":4,"studyType":23,"phases":479,"briefSummary":480,"conditions":481,"keywords":485,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":462,"lastUpdatePostDateStruct":490,"startDateStruct":491,"completionDateStruct":493,"leadSponsor":495,"locationsCount":50},"100532403","therapeutic-educational-physiotherapy-on-pain-physical-functionality-and-quality-of-life-in-women-with-endometriosis-100532403","NCT06212349","Therapeutic-educational Physiotherapy on Pain, Physical-functionality and Quality of Life in Women With Endometriosis.","Effect of a Therapeutic-educational Physiotherapy Program on Pain and the Physical-functional Sphere in Women With Endometriosis and Its Impact on Quality of Life","PHYSIO_ENDOM","Inclusion Criteria:\n\n* Diagnosis of endometriosis made by imaging techniques (MRI or ultrasound) or by surgery.\n* A period of 3 months or more since the last surgery if they have undergone surgery.\n* Who are receiving hormone treatment and have their disease under control.\n* Persistent pelvic pain for at least 3 months.\n* With pain and hypertonus in the pelvic musculature, myofascial syndrome, vestibulodynia or pudendal neuropathy.\n* Consent to participate in the study\n* Capable of carrying out the follow-up of the study until the final visit.\n* Who have audiovisual resources and the internet at their disposal.\n\nExclusion Criteria:\n\n* Women in the menopausal phase\n* Women undergoing fertility treatment or planning to undergo fertility treatment in the next 3 months.\n* Pregnant women.\n* Women undergoing physiotherapy treatment or who have undergone physiotherapy treatment in the last 3 months.\n* Having suffered a fracture in the last 3 months in the lower limb that limits their functional capacity.\n* Cognitive illness that prevents correct comprehension of the exercises.\n* Musculoskeletal pathology or neuropathy in acute phase.\n* Having suffered or suffering from a neoplastic disease.\n* Untreated endometriosis\n* Acquired genital abnormalities of the pelvis or pelvic floor.\n* Women in a situation of litigation or economic compensation, or pending the granting of a degree of disability.\n* Severe mental illness (schizophrenia, borderline personality disorder, etc.)",{"count":478,"type":22},62,[25],"This is a randomized clinical trial that will be carried out in women with endometriosis divided into two groups: the experimental group (EG) that will receive therapeutic-educational physiotherapy, which will combine therapeutic exercise with a pain education program, and the control group (CG) who will receive the pain education program.\n\nThe participants will be evaluated at three moments: before starting the study (T1), after the 8-week treatment program (T2) and after another 8 weeks of follow-up in which they will be encouraged to continue with the treatment (T3). The initial assessment will include a medical and physiotherapy history, and at T1, T2 and T3 the following will be assessed: pain, abdominopelvic mobility, muscle status, functionality, sexual function, quality of life, stress and biomarkers of chronic inflammation.",[482,483,484],"Endometriosis","Chronic Pain","Women's Health",[486,483,487,488,489],"endometriosis","Physical Therapy","Health education","Women",{"date":433,"type":42},{"date":492,"type":42},"2024-09-09",{"date":494,"type":22},"2027-12-22",{"name":48,"class":49},{"id":497,"slug":498,"hasResults":12,"nctId":499,"briefTitle":500,"officialTitle":501,"acronym":4,"eligibilityCriteria":502,"healthyVolunteers":17,"sex":18,"minAge":503,"maxAge":504,"enrollmentInfo":505,"targetDuration":4,"studyType":23,"phases":507,"briefSummary":508,"conditions":509,"keywords":515,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":525,"lastUpdatePostDateStruct":526,"startDateStruct":528,"completionDateStruct":530,"leadSponsor":532,"locationsCount":50},"100609281","emotichealth-promoting-adolescent-health-through-a-serious-game-100609281","NCT07212530","EmoTIChealth: Promoting Adolescent Health Through a Serious Game.","\"Promoting Health in Adolescents With and Without Chronic Diseases Through Emotional Development: Design and Implementation of a Serious Game Technology Platform (EmoTIChealth)\"","Inclusion Criteria:\n\n* Informed consent by parents\u002Fguardians and participants.\n* Aged between 12 and 16 years old\n\nExclusion Criteria:\n\n* No access to internet or new technologies\n* Not a Spanish speaker.","12 Years","16 Years",{"count":506,"type":22},600,[25],"The intervention program targets adolescents between 12 and 16 years of age. The intervention program is designed for adolescents during a critical developmental stage marked by significant life transitions, where building strong personal resources and receiving psychological support is essential to foster socioemotional skills and overall well-being. The serious game aims to promote psycho-emotional health in the general adolescent population, supporting healthy development and preventing future emotional difficulties. At the same time, it incorporates specific modules for adolescents living with chronic conditions such as asthma, food allergy, type 1 diabetes, and allergic rhinitis, who may face additional risks of psychological challenges that can complicate treatment and prognosis. By combining universal health promotion with tailored support, the program addresses both the needs of healthy adolescents and those with chronic illnesses.\n\nThe platform integrates digital and technological tools for dynamic and personalized intervention. Artificial intelligence adapts activities and feedback to each participant's socio-demographic profile and evolving needs, this supports directly in participants' daily lives and natural environments, making the experience more relevant and impactful. The serious game, proven effective in engaging young people, goes beyond traditional psychoeducation by creating an interactive environment where adolescents develop socio-emotional competencies, resilience, and health-related knowledge. Through its six thematic areas, the game promotes overall well-being and healthy habits, while its condition-specific modules provide targeted guidance and coping strategies for asthma, food allergies, type 1 diabetes, and allergic rhinitis.",[510,511,512,513,514],"Type 1 Diabetes","Asthma","Allergic Rhinitis","Food Allergy","Adolescent Development",[510,511,512,516,517,518,519,520,521,522,523,524],"Food allergy","Serious Game","Technology platform","Psychological intervention","Adolescence","Quality of life","chronic organic illnesses","Socioemotional Education","Health Promotion","2026-05-12",{"date":527,"type":42},"2026-05-13",{"date":529,"type":42},"2025-12-01",{"date":531,"type":22},"2027-08-30",{"name":48,"class":49},{"id":534,"slug":535,"hasResults":12,"nctId":536,"briefTitle":537,"officialTitle":538,"acronym":4,"eligibilityCriteria":539,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":540,"targetDuration":4,"studyType":23,"phases":542,"briefSummary":543,"conditions":544,"keywords":547,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":553,"lastUpdatePostDateStruct":554,"startDateStruct":555,"completionDateStruct":557,"leadSponsor":559,"locationsCount":50},"100574426","romsi-mobile-health-intervention-to-enhance-suicide-prevention-by-reducing-stigma-and-increasing-literacy-100574426","NCT06759129","RomSi: Mobile Health Intervention to Enhance Suicide Prevention by Reducing Stigma and Increasing Literacy","RomSi (Rompiendo el Silencio) Mobile Health Intervention to Enhance Suicide Prevention by Reducing Stigma and Increasing Literacy: Protocol for a Cross-Over Randomized Controlled Trial","Inclusion Criteria:\n\n* Be 18 years old or older.\n* Have a cell phone with internet access during the intervention and follow-up periods.\n* Be able to speak, understand, and read in Spanish.\n\nExclusion Criteria:\n\n* Presence of high suicidal ideation (measured during screening, with a score above 20 on the total SIDAS scale or between 7 and 10 on the item assessing suicide attempts).\n* Presence of high social desirability bias (measured during screening, with a score of 14 or higher on the MC-SDS scale).\n* Altered mental status that impedes the ability to provide informed consent or assent (e.g., acute psychosis, intoxication, or mania).",{"count":541,"type":22},214,[25],"Suicide is one of the leading causes of death in Spain, representing a public health crisis that requires urgent and effective solutions. The stigma surrounding suicide prevents many at-risk individuals from seeking help, worsening the problem. Addressing this stigma is essential to implement more effective and accessible prevention strategies. This study aims to design and evaluate an innovative mobile health intervention to reduce stigma and encourage help-seeking behaviours in the general population. While the intervention targets the general population, two specific groups will access specialized and tailored content: individuals with low suicidal ideation and family members or close friends of people who have died by suicide. A daily assessment will collect real-time data and evaluate the intervention's impact. The study will employ a randomised controlled trial (RCT) with a crossover design, with participants randomly assigned to immediate or delayed use conditions. The intervention's effectiveness and usability will be assessed at four key points through quantitative analyses and qualitative interviews. We hypothesise that the intervention will improve suicide literacy, reduce suicide-related stigma, increase help-seeking behaviours, and demonstrate high usability and acceptability.",[545,546],"Suicidal Ideation and Behavior","Suicide",[548,549,550,551,552],"Suicide Prevention","Stigma","Suicide Literacy","Help Seeking","Randomized Controlled Trial","2026-05-07",{"date":525,"type":42},{"date":556,"type":42},"2025-10-15",{"date":558,"type":22},"2027-01",{"name":48,"class":49},{"id":561,"slug":562,"hasResults":12,"nctId":563,"briefTitle":564,"officialTitle":565,"acronym":566,"eligibilityCriteria":567,"healthyVolunteers":12,"sex":59,"minAge":123,"maxAge":60,"enrollmentInfo":568,"targetDuration":4,"studyType":23,"phases":569,"briefSummary":570,"conditions":571,"keywords":574,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":577,"lastUpdatePostDateStruct":578,"startDateStruct":580,"completionDateStruct":582,"leadSponsor":584,"locationsCount":4},"100640984","comparative-effects-of-kinesio-taping-on-cervical-pain-in-climacteric-women-100640984","NCT07577297","Comparative Effects of Kinesio Taping on Cervical Pain in Climacteric Women","Comparative Study on the Effect of Kinesio Taping in Climacteric Women With Nonspecific Cervical Pain: ARandomized Clinical Trial.","KT-Cerv-W","Inclusion Criteria:\n\nFemale participants aged 45-65 years Non-specific musculoskeletal or osteoarticular cervical pain lasting more than 3 months Mechanical neck pain characteristics (pain influenced by movement or posture; absence of persistent non-mechanical nocturnal pain) Ability to understand the study procedures and provide written informed consent No clinical history or signs suggestive of specific cervical pathology\n\nExclusion Criteria:\n\nPresence of any red flags Recent cervical trauma History of cancer or presence of constitutional symptoms (e.g., unexplained weight loss, fever, systemic malaise) Signs of infection or immunosuppression-related pain Active inflammatory disease Suspected vascular origin of symptoms (e.g., vertigo with cervical rotation, diplopia, dysarthria, vertebrobasilar symptoms, arterial dissection signs) Severe neurological involvement (e.g., progressive radiculopathy or signs of myelopathy) Relevant findings in previous imaging studies attributable to pain (routine imaging not required; only existing studies will be reviewed) Cervical surgery within the past 12 months Severe systemic diseases affecting the musculoskeletal system",{"count":173,"type":22},[25],"This randomized controlled clinical trial aims to evaluate the effects of neuromuscular taping on cervical pain and health-related quality of life in climacteric women with non-specific chronic neck pain. Two taping techniques (\"Y-strip\" and \"star-shape\") will be compared with a control group receiving no intervention.\n\nParticipants will be randomly allocated to one of three groups following concealed allocation. The interventions will be applied to the cervicodorsal region (centered at C7) by an experienced physiotherapist over a 3-week period, with taping changes performed weekly. A 4-week total follow-up period will be included.\n\nPrimary and secondary outcomes will assess pain intensity, pressure pain threshold, cervical disability, cranio-cervical angle, pain perception, body satisfaction, and health-related quality of life. Measurements will be collected at baseline, weekly during the intervention, and at one-week post-intervention follow-up.\n\nThe study is designed to provide evidence on the effectiveness and feasibility of two non-invasive neuromuscular taping approaches in the management of chronic non-specific cervical pain in middle-aged women.",[572,573],"Climacteric Women","Nonspecific Cervical Pain",[575,576,572],"Kinesio Taping","Cervical Pain","2026-05-02",{"date":579,"type":42},"2026-05-11",{"date":581,"type":22},"2026-05-20",{"date":583,"type":22},"2026-09-30",{"name":48,"class":49},{"id":586,"slug":587,"hasResults":12,"nctId":588,"briefTitle":589,"officialTitle":590,"acronym":4,"eligibilityCriteria":591,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":60,"enrollmentInfo":592,"targetDuration":4,"studyType":23,"phases":593,"briefSummary":594,"conditions":595,"keywords":597,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":603,"lastUpdatePostDateStruct":604,"startDateStruct":606,"completionDateStruct":608,"leadSponsor":610,"locationsCount":50},"100636059","contribution-of-a-to-dental-bleaching-after-combined-dental-bleaching-100636059","NCT07560761","Contribution of a* to Dental Bleaching After Combined Dental Bleaching","Contribution of the a* Parameter to Dental Bleaching After Combined Bleaching: A Prospective Non-randomized Single-arm Interventional Clinical Study","Inclusion Criteria\n\n* Age 18 to 65 years\n* Good oral health\n* Presence of natural anterior teeth (incisors, canines, premolars)\n* Anterior teeth without restorations\n* Indication for tooth bleaching treatment\n* Ability to comply with study procedures and visits\n\nExclusion Criteria\n\n* Smoking\n* Previous tooth bleaching treatment\n* Pregnancy\n* Breastfeeding\n* Restorations in anterior teeth\n* Presence of diseases affecting tooth color\n* Conditions that may interfere with study outcomes",{"count":369,"type":22},[25],"A prospective, non-randomized, single-arm interventional clinical study with a before-after design will be conducted to assess changes in CIELab color parameters and the Whiteness Index for Dentistry (WID) following a standardized combined dental bleaching protocol. The study aims to evaluate the contribution of the a\\* parameter (green-red axis) to overall dental whiteness.",[596],"Healthy",[598,599,600,601,602],"Dental bleaching","Tooth color","CIELab","Whiteness Index","Spectrophotometry","2026-04-30",{"date":605,"type":42},"2026-05-06",{"date":607,"type":22},"2026-10-01",{"date":609,"type":22},"2027-07",{"name":48,"class":49},{"id":612,"slug":613,"hasResults":12,"nctId":614,"briefTitle":615,"officialTitle":616,"acronym":4,"eligibilityCriteria":617,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":60,"enrollmentInfo":618,"targetDuration":4,"studyType":23,"phases":619,"briefSummary":620,"conditions":621,"keywords":622,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":623,"lastUpdatePostDateStruct":624,"startDateStruct":626,"completionDateStruct":628,"leadSponsor":630,"locationsCount":50},"100610817","exercise-induced-hypoalgesia-effects-of-blood-flow-restriction-in-people-with-rotator-cuff-related-shoulder-pain-100610817","NCT07232511","Exercise-induced Hypoalgesia Effects of Blood Flow Restriction in People With Rotator Cuff-related Shoulder Pain","Differences in Exercise-induced Hypoalgesia After a Session With Different Blood Flow Restriction Protocols in People With Rotator Cuff-related Shoulder Pain","Inclusion Criteria:\n\n* Age between 18 and 65\n* Shoulder symptoms lasting at least 3 months\n* Pain in the proximal anterolateral aspect of the shoulder, aggravated by abduction\n* At least two of the following tests positive: Jobe test, resisted external rotation test, Hawkins-Kennedy test, Neer test, painful arc between 60 and 120 degrees of shoulder abduction\n\nExclusion Criteria:\n\n* History of shoulder trauma or surgery\n* Pain of such intensity that it is impossible to perform the proposed exercises\n* Active arm elevation less than 90 degrees\n* Clinical signs of a complete tear (positive delayed external and internal rotation sign and positive arm drop test)\n* Suspected frozen shoulder (50% reduction or more than 30° loss in passive shoulder external rotation)\n* Primary diagnosis of shoulder instability or acromioclavicular pathology\n* Shoulder pain due to primary involvement in the cervical or thoracic region\n* Corticosteroid injections in the last 6 weeks\n* Presence of diseases such as inflammatory arthritis, neurological diseases, fibromyalgia, malignant tumors, or polymyalgia rheumatica\n* Presence of more than one risk factor for thromboembolism\n* Participation in upper limb exercise programs in the last month",{"count":21,"type":22},[25],"This study aims to compare the effects of blood flow restricted (BFR) exercise and to examine the differences between various BFR protocols on acute pain reduction in individuals with rotator cuff-related shoulder pain, as well as the exercise tolerance at each intensity and occlusion setting. There are four exercise modalities corresponding to different combinations of intensity (%RM) and percentage of occlusion (%AOP): 1) 30% RM and 30% AOP; 2) 30% RM and 50% AOP; 3) 30% RM and 70% AOP; 4) 30% RM and BFR placebo (cuff without pressure).\n\nAll participants will complete one session of each of the four exercise modalities, analyzing the variables studied in each for subsequent analysis and comparison.",[272],[209,210,274],"2026-04-28",{"date":625,"type":42},"2026-05-04",{"date":627,"type":42},"2026-03-05",{"date":629,"type":22},"2026-12",{"name":48,"class":49},{"id":632,"slug":633,"hasResults":12,"nctId":634,"briefTitle":635,"officialTitle":636,"acronym":4,"eligibilityCriteria":637,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":60,"enrollmentInfo":638,"targetDuration":4,"studyType":23,"phases":639,"briefSummary":640,"conditions":641,"keywords":643,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":623,"lastUpdatePostDateStruct":646,"startDateStruct":648,"completionDateStruct":650,"leadSponsor":651,"locationsCount":50},"100550401","telerehabilitation-based-exercises-vs-standard-home-based-exercise-in-low-back-pain-100550401","NCT06446596","Telerehabilitation-based Exercises vs Standard Home-based Exercise in Low Back Pain","Effect of the Implementation of Telerehabilitation-based Exercises Compared to the Standard Use of Exercise Dossier and Intervention Diary in a Home Therapeutic Exercise Intervention in Patients With Low Back Pain","Inclusion Criteria:\n\n* Nonspecific subacute or chronic low back pain\n\nExclusion Criteria:\n\n* Neuropathic pain\n* Pain below the knees\n* Pain in legs with tingling, sensation of current or sensory alterations\n* Positive neurological tests. Lack of strength, sensitivity or altered reflexes\n* Canal stenosis\n* Nociplastic pain (fibromyalgia, generalized pain, emotional lability, affective and cognitive implications)\n* Previous lumbar surgery\n* Specific pathology (rheumatic, spondylolisthesis, oncological, fractures...)\n* Pregnancy\n* Performing medium-high intensity exercise of more than 100 minutes a week\n* Pathology that prevents exercise (decompensated cardiac pathology, decompensated respiratory pathology, significant mobility difficulties...)\n* Lack of digital skills\n* Visual problems that prevent exercise with the phone screen",{"count":21,"type":22},[25],"The objective of the study is to compare the effect of a telerehabilitation-based exercise program, versus a home therapeutic exercise program scheduled through a dossier and an exercise diary, with respect to disability (measured using the OSWESTRY questionnaire) and other variables (range of motion, strength, fatigue, histological changes, pain, medication intake, psychosocial factors and adherence), in patients with low back pain.",[642],"Low Back Pain",[644,210,645],"low back pain","telerehabilitation",{"date":647,"type":42},"2026-04-29",{"date":649,"type":42},"2024-11-04",{"date":629,"type":22},{"name":48,"class":49},{"id":653,"slug":654,"hasResults":12,"nctId":655,"briefTitle":656,"officialTitle":657,"acronym":4,"eligibilityCriteria":658,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":659,"targetDuration":4,"studyType":23,"phases":661,"briefSummary":662,"conditions":663,"keywords":664,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":623,"lastUpdatePostDateStruct":669,"startDateStruct":670,"completionDateStruct":672,"leadSponsor":674,"locationsCount":50},"100542258","comparison-of-the-perception-of-non-technical-skills-100542258","NCT06340529","Comparison of the Perception of Non-technical Skills","Comparison of the Perception of Non-technical Skills by Students, Self-assessment and Teachers, Developed During the Clinical Simulation in Students of the Degree in Physiotherapy","Inclusion Criteria:\n\n* Second year students of the Physiotherapy Degree\n* They do not have clinical experience with real patients.\n* Subject teachers\n\nExclusion Criteria:\n\n* Not wanting to sign to participate in the study.\n* Not signing the informed consent\n* Teachers who do not have experience in clinical simulation",{"count":660,"type":22},100,[25],"Clinical simulation has recently acquired great importance in the health sciences. It is a pedagogical methodology that is increasingly used in health science degrees, since it is very useful for the acquisition of both technical and non-technical skills (leadership, teamwork and effective communication, among others).\n\nHowever, if the investigators focus on physical therapy, the use of clinical simulation is a novel field and therefore requires a great deal of research. Researchers in this field do not yet have the consistency and experience as in other health branches such as medicine or nursing, where the participants have been using high-fidelity simulators for years for the learning of all their students.\n\nClinical simulation allows students to achieve these competencies without the need to practice on real patients. For all these reasons, and because of the situation of need generated in recent years, in which internships in hospitals and clinical centers were completely suppressed, the need for our research is justified.",[596],[665,666,667,668],"Physioterapy","Students","Clinical Simulation","Learning methodology",{"date":647,"type":42},{"date":671,"type":42},"2025-05-30",{"date":673,"type":22},"2027-06-30",{"name":48,"class":49},""]