[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of the State of Santa Catarina\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":101},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100629025","high-intensity-progressive-inspiratory-muscle-training-in-class-iii-obesity-and-obstructive-sleep-apnea-100629025",false,"NCT07469280","High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea","High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea: Study Protocol for a Prospective Nonconcurrent Multiple-Baseline Single-Case Experimental Design With Stability-Based Phase Transition","Inclusion Criteria: -Adults (≥18 years).\n\n* Of both genders.\n* Class III obesity (BMI \\> 40 kg\u002Fm²).\n* Diagnosis of OSA.\n* Without neurological conditions that would prevent them from responding to the study assessments.\n\nExclusion Criteria:\n\n* Systemic diseases (pulmonary, cardiac or renal).\n* Are using medications that may affect muscle performance.\n* Are currently using CPAP therapy.\n* Conditions that could compromise adherence to the study protocol.","ALL","18 Years",{"count":19,"type":20},10,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg\u002Fm²) and obstructive sleep apnea (OSA). Using a single-case experimental design (SCED) with multiple baselines, the study will investigate whether this respiratory intervention can reduce the severity of sleep apnea, as measured by the Apnea-Hypopnea Index (AHI), and improve inspiratory muscle strength and sleep quality. Participants will perform daily training sessions using a resistive loading device (POWERbreathe), with intensity progressing from 40% to 90% of their maximum inspiratory pressure.",[26,27,28],"Obesity, Class III","Sleep Apnea, Obstructive","Inspiratory Muscle Training",[30,31,32,33],"Class III obesity","Inspiratory muscle training","Obstructive sleep apnea","Single-case experimental design","NOT_YET_RECRUITING","2026-03-18",{"date":37,"type":38},"2026-03-23","ACTUAL",{"date":40,"type":20},"2026-05-01",{"date":42,"type":20},"2027-12-01",{"name":44,"class":45},"University of the State of Santa Catarina","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":16,"minAge":17,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100553359","myofascial-reorganization-on-performance-and-biomechanical-viscoelastic-and-thermographic-properties-of-athletes-100553359","NCT06485063","Myofascial Reorganization on Performance, and Biomechanical, Viscoelastic, and Thermographic Properties of Athletes","Effects of Myofascial Reorganization on Running Performance, and Lower Limb Biomechanical, Viscoelastic, and Thermographic Properties of Triathletes: a Randomized Clinical Trial.","Inclusion Criteria:\n\n* Athletes\n* Age between 18 and 45 years\n* 2 years of competitive experience\n* Non-smokers\n* Training at least 3 times\u002Fweek intending to compete in at least local competitions\n* No presenting lower limb surgery in the last 12 months\n* Not presenting lower limb injury in the last 6 months\n* Not presenting cerebellar diseases that limit sportive practice\n* Not presenting brain diseases that limit sportive practice\n* Not presenting musculoskeletal diseases that limit sportive practice\n* Not presenting signs of rhabdomyolysis\n* Not presenting systemic conditions that limit sportive practice\n* Not presenting metabolic that limits sports practice\n* Not presenting autoimmune conditions;\n* Not presenting cardiac conditions.\n\nExclusion Criteria:\n\n* Not accomplishing 83,3% (10 of 12 sessions) of the proposed experimental\u002Fplacebo protocol\n* Not presenting themselves on the re-test day\n* Developing a lower limb musculoskeletal injury during the study's ongoing period.\n* Developing a back injury during the study's ongoing period?\n* Developing central or peripheral nervous system conditions during the study's ongoing period.",true,"45 Years",{"count":57,"type":20},60,[23],"This is a two-group randomized clinical trial (includes an experimental and a placebo group) to verify the effects of the Myofascial Reorganization (RMF) compared to the placebo-RMF technique on running performance and thermographic, biomechanical, and viscoelastic proprieties of lower limbs of male triathletes. Data collection will be carried out one week before the first intervention session, and one week after the last intervention session. Anthropometric characteristics (height and weight), lower limbs, and biomechanical, viscoelastic, and thermographic properties will be collected before any exercise tests. After this, the athlete will be submitted to: a 10-minute protocol to verify running economy on the treadmill, followed by an incremental test on the treadmill, and a time to exhaustion test. Evaluation procedures will carried out one week before (0 weeks) and one week after (7th week) the experimental\u002Fplacebo intervention. Intervention sessions will occur during six weeks, twice a week, each session lasting up to 30 minutes.",[61],"Healthy",[63,64,65,66],"athletes","performance","healthy","fascia","RECRUITING","2024-06-26",{"date":70,"type":38},"2024-07-03",{"date":72,"type":38},"2024-04-15",{"date":74,"type":20},"2025-12-31",{"name":44,"class":45},{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":21,"phases":87,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":4},"100520339","effects-of-intradialytic-aerobic-exercise-in-chronic-kidney-patients-100520339","NCT06055283","Effects of Intradialytic Aerobic Exercise in Chronic Kidney Patients","Effects of Intradialytic Aerobic Exercise on Peripheral Muscle Function, Functional Status and Motivation in Chronic Kidney Patients: A Randomized Controlled Clinical Trial","IAECKD","Inclusion Criteria:\n\n* diagnosis of chronic kidney disease undergoing renal replacement therapy via hemodialysis\n* aged 20 to 65 years\n* low body mass index at overweight (21 kg\u002Fm2 to 29.9 kg\u002Fm2)\n* regular renal replacement therapy via hemodialysis for 6 months, without acute complications related to the diagnosis and\u002For comorbidities for the period of 3 months prior to the evaluation and intervention.\n\nExclusion Criteria:\n\n* patients who do not reach a score equal to or above 20 assessed by the Mini Mental State Examination\n* severe heart failure according to the New York Heart Association classification\n* musculoskeletal alteration that prevents the correct execution of the assessment activities\n* who have participated in other exercise protocols in the last 6 months prior to the present study\n* patients who show signs of clinical instability during the hemodialysis procedure or after training for two consecutive sessions will be excluded throughout the protocol.","65 Years",{"count":86,"type":20},90,[23],"The goal of this clinical trial is to evaluate the effects of intradialytic aerobic exercise on muscle capacity, functionality and motivation of patients with chronic kidney disease undergoing hemodialysis.\n\nThe main question it aims to answer are:\n\n• Is intradialytic aerobic exercise at moderate intensity effective in improving peripheral muscle function, functional status and motivation in patients with chronic kidney disease?",[90],"Chronic Kidney Diseases",[92],"Chronic Kidney Disease","2023-09-19",{"date":95,"type":38},"2023-09-26",{"date":97,"type":20},"2023-11",{"date":99,"type":20},"2026-12-31",{"name":44,"class":45},""]