[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"VA Palo Alto Health Care System\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":122},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,39,70,96],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100565779","group-advanced-care-planning-pilot-for-veterans-100565779",false,"NCT06646614","Group Advanced Care Planning Pilot for Veterans","Inclusion Criteria:\n\n1. All patients \\>18 years old with newly diagnosed cancer are eligible.\n2. Patients must have the ability to understand and willingness to provide verbal consent\n3. Participants must speak English\n\nExclusion Criteria:\n\n1. Inability to consent to the study\n2. Plans to move within the area and leave the VA system within 4 months","ALL","18 Years",{"count":18,"type":19},50,"ESTIMATED","INTERVENTIONAL",[22],"NA","The proposed research aims to engage participants in group educational sessions to facilitate learning of topics related to advanced care planning and to determine whether this approach is more effective than usual care alone.",[25],"Cancer","RECRUITING","2026-01-26",{"date":29,"type":30},"2026-01-28","ACTUAL",{"date":32,"type":30},"2025-07-15",{"date":34,"type":19},"2027-12-01",{"name":36,"class":37},"VA Palo Alto Health Care System","FED",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":4,"eligibilityCriteria":44,"healthyVolunteers":11,"sex":15,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":4,"studyType":20,"phases":49,"briefSummary":50,"conditions":51,"keywords":57,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":38},"100548033","developing-functional-connectivity-guided-tms-for-alcohol-use-disorder-100548033","NCT06415721","Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder","Inclusion Criteria:\n\n* Between age 25 and 75.\n* Current DSM-5 diagnosis of moderate to severe AUD (≥4 diagnostic symptoms).\n* Able to attend scheduled clinic visits\n* Able to read, understand and voluntarily sign Informed Consent prior to participating in any study-specific procedures or assessments.\n* If on a medication regimen, that regimen will be stable for the duration of the study;\n* Fluency in English.\n\nExclusion Criteria:\n\n* Transcranial magnetic stimulation (TMS) and magnetic resonance imaging (MRI) contraindications: such as a cardiac pacemaker, cochlear implant, or an implanted device (deep brain stimulation, metal in the head, metal in the body, claustrophobia, pregnant or breastfeeding or other ferromagnetic device\u002Fobjected in the head and body within 30 cm of the treatment coil.\n* General medical condition, disease or neurological disorder that interferes with the assessments or participation.\n* Unable to safely withdraw, at least two weeks prior to treatment, from medications that increase seizure risk.\n* Current substance abuse (except caffeine or nicotine) as determined by positive toxicology screen.\n* Have a mass lesion, cerebral infarct, or other active CNS disease, including an alcohol-related seizure or a seizure disorder. • A recent suicide attempt (defined as within the last 30 days) or presence of current suicidal plan or intent. Patients at risk for suicide will be required to establish a written safety plan involving their primary therapist before entering the study.\n* Severe impediment to vision, hearing and\u002For hand movement, likely to interfere with the ability to follow study protocols. • Greater than mild traumatic brain injury (defined as greater than 10 minutes loss of consciousness).\n* Taking benzodiazepine or neuroleptic medications, or any medication known to alter seizure threshold\n* unstable chronic illness.\n* Current or lifetime history of bipolar disorder or psychosis.\n* Participation in another concurrent intervention based clinical trial.","25 Years","75 Years",{"count":48,"type":19},40,[22],"Alcohol Use Disorders are currently positioned as the third leading cause of preventable death in the United States, constituting a humanitarian crisis with substantial financial burden on society and medical facilities. While several pharmacological interventions exist, 60% of individuals who seek these treatments relapse to alcohol within 6 months. These high relapse rates are due in part to elevated brain response to alcohol cues in the environment. This study seeks to evaluate the efficacy of one session of functional Magnetic Resonance Imaging (fMRI) guided transcranial magnetic stimulation (TMS) as a strategy to reduce brain reactivity to alcohol cues.",[52,53,54,55,56],"Alcohol Use Disorder","Alcohol Abuse","Alcoholism","Drinking Behavior","Drinking Problem",[58,59,60,61],"Transcranial Magnetic Stimulation","Veterans","Neuroimaging","Relapse","2025-08-07",{"date":64,"type":30},"2025-08-13",{"date":66,"type":19},"2025-08-25",{"date":68,"type":19},"2026-01-01",{"name":36,"class":37},{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":20,"phases":78,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":4},"100599390","testing-the-insomnia-coach-mobile-app-with-veterans-with-insomnia-and-ptsd-100599390","NCT07083869","Testing the Insomnia Coach Mobile App With Veterans With Insomnia and PTSD","Inclusion Criteria:\n\n* U.S. military Veteran\n* Aged 18 years or older\n* Owner of smartphone or tablet with Android or iOS operating system\n* Probable insomnia (i.e., ISI \\>=15)\n* Probable PTSD (i.e., PCL-5 \\>=31)\n* Able to read\u002Fwrite English\n* Internet connection and active email address\n\nExclusion Criteria:\n\n* Comorbid sleep disorders (apnea, RLS, narcolepsy)\\*\n* Started or changed dosage of sleep medications or SSRIs in past 2 months\n* Unstable housing\n* Medical condition identifiably causing sleep problems\n* Current mania or psychosis or seizure-related disorder\n* Currently receiving or having recently received insomnia therapy resembling CBT-I\n* Shift working\n* Pregnant\n* Newborn (3 mos. or younger) living in residence",{"count":77,"type":19},130,[22],"The objective of this randomized controlled trial of the Insomnia Coach mobile app is to evaluate the potential effects of app use on reducing insomnia symptoms among Veterans with significant insomnia and PTSD symptoms. It is also intended to evaluate the impact of the app on other outcomes, including PTSD, depression, and anxiety symptoms, and psychosocial functioning. Finally, the study is designed to assess perceptions of Insomnia Coach regarding its perceived helpfulness, satisfaction, and likes\u002Fdislikes to inform its continued improvement. The results of this study will inform the next steps of research evaluating Insomnia Coach with Veterans with significant insomnia and PTSD symptoms, namely a larger-scale, VA ORD or NIH funded randomized controlled trial.",[81,82],"Insomnia","Posttraumatic Stress Disorder (PTSD)",[84,85,86],"Mobile app","Veteran","Cognitive Behavioral Therapy for Insomnia","NOT_YET_RECRUITING","2025-07-21",{"date":90,"type":30},"2025-07-24",{"date":92,"type":19},"2025-08-01",{"date":94,"type":19},"2027-12-31",{"name":36,"class":37},{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":46,"enrollmentInfo":103,"targetDuration":4,"studyType":20,"phases":105,"briefSummary":106,"conditions":107,"keywords":109,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":121,"locationsCount":38},"100526896","feasibility-of-home-based-transcutaneous-spinal-cord-stimulation-for-persons-with-sci-100526896","NCT06140706","Feasibility of Home Based Transcutaneous Spinal Cord Stimulation for Persons With SCI","Feasibility of a Video Telehealth Model to Evaluate Home Use of Transcutaneous Spinal Cord Stimulation for Enhanced Upper Limb Function","Inclusion Criteria:\n\n1. Veteran\n2. Age 18-65\n3. All gender, any ethnicity\n4. Cervical Spinal Cord Injury C2-8\n5. American Spinal Injury Association (ASIA) Impairment Scale (AIS) B, C or D\n6. GRASSP-Prehension Score \\>10 or GRASSP Strength Score \\>30\n7. Greater than 1 year post injury\n8. Able to identify a companion to assist with neurostimulator setup in home environment.\n9. Internet connection to support video telehealth connection\n10. Willingness to travel to the VA Palo Alto Medical Center\n\nExclusion Criteria:\n\n1. Cardiopulmonary disease or cardiac symptoms,\n2. Autonomic dysreflexia that is uncontrolled or severe,\n3. Implanted medical device(s),\n4. Uncontrolled spasms that could limit participation in exercise training,\n5. Skin breakdown or active pressure injury in areas of electrode placement.\n6. Participants must not be engaged in any concurrent drug or device trial\n7. Pregnant, are planning to become pregnant, or breastfeeding\n8. The study is not deemed safe or appropriate in the opinion of the investigators",{"count":104,"type":19},10,[22],"The proposed study will focus on the feasibility of and effectiveness to a home-based program for persons with chronic SCI focused on upper limb training augmented with a transcutaneous neurostimulator supported via a video telehealth platform.",[108],"Tetraplegia",[110,111,112,113,114],"paralysis","exercise","telemedicine","spinal cord stimulation","physical activity","2025-04-07",{"date":117,"type":30},"2025-04-10",{"date":119,"type":19},"2025-09-01",{"date":94,"type":19},{"name":36,"class":37},""]