[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"VASCage GmbH\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":138},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,49,79,108],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100632298","digital-application-for-stroke-health-100632298",false,"NCT07511868","Digital Application for Stroke Health","Evaluating a Digital Health Application for Post-stroke Care and Vascular Risk Factor Management - a Multicenter Randomized Controlled Clinical Investigation","DASH","Inclusion Criteria:\n\n1. Male or female patient (biological sex) ≥18 years at the time of consent\n2. Hospitalization for acute ischemic stroke, acute haemorrhagic stroke or TIA\n3. Necessary Technical Equipment (smartphone or tablet computer) and skills\n4. Able to provide informed consent\n\nExclusion Criteria:\n\n1. Cerebral infarction due to cerebral venous thrombosis (CVT)\n2. Severe Psychiatric Conditions\n3. Severe pre-existing cognitive impairment\n4. Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) or other patients where salt restriction is harmful.\n5. Inability to operate the device independently (assistance from a caregiver is acceptable). E.g.:\n\n   * Severe apraxia,\n   * Severe Motor Disabilities,\n   * Severe Visual Impairment\n   * Severe Communication Barriers (e.g. Severe Aphasia, Severe Dysarthria)\n6. Inability to speak and read German to a level which allows fully comprehending the meaning of everything that is said and written.\n7. Women of childbearing potential not willing to adopt effective contraceptive measures during the clinical investigation\n8. Patients who are considered to be part of the vulnerable population:\n\n   * Persons unable to give consent\n   * Minors\n   * Persons performing military service\n   * persons detained by court or official order or accommodated in accordance with the Accommodation Act, Federal Law Gazette No. 155\u002F1990\n   * Pregnant or breastfeeding women","ALL","18 Years",{"count":20,"type":21},500,"ESTIMATED","INTERVENTIONAL",[24],"NA","Stroke is a leading cause of death and long-term disability worldwide. Despite substantial advances in acute stroke care, there remains a lack of evidence-based digital solutions to support patients after hospital discharge. This study evaluates the effectiveness of a digital health application (StrokeApp) designed to support patients with ischemic or hemorrhagic stroke or transient ischemic attack (TIA) in secondary prevention and recovery.\n\nIn this multicenter, randomized, controlled, open-label trial, 500 patients will be assigned in a 1:1 ratio to receive either standard care alone or standard care in combination with StrokeApp. The primary objective is to assess the impact of the application on health-related quality of life three months after discharge. Secondary and exploratory outcomes include health literacy, medication adherence, vascular risk factors, health-related behaviors, psychosocial outcomes, long-term recovery up to twelve months, as well as safety and user experience.",[27,28,29],"Haemorrhagic Stroke","Ischaemic Stroke","Transient Ischemic Attack (TIA)",[31,32,33,34,35],"Digital Health Application","Post Stroke","Medical Device","App","stroke aftercare","NOT_YET_RECRUITING","2026-03-30",{"date":39,"type":40},"2026-04-06","ACTUAL",{"date":42,"type":21},"2026-04-01",{"date":44,"type":21},"2026-12-31",{"name":46,"class":47},"VASCage GmbH","OTHER",7,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},"100588379","exploratory-study-on-the-potential-cross-system-effects-of-bci-fes-hand-therapy-on-dysphagia-and-aphasia-in-chronic-stroke-patients-100588379","NCT06940635","Exploratory Study on the Potential Cross-System Effects of BCI-FES Hand Therapy on Dysphagia and Aphasia in Chronic Stroke Patients","Cross-Stroke Therapy Effects With BCI and FES Stimulation: A Pilot Study","c-STEPS","Inclusion Criteria:\n\n* Age: Participants must be aged 18 years or older.\n* Post-Stroke Phase: Participants must be within the chronic post-stroke phase (time since ischemic or haemorrhagic stroke greater than 3 months).\n* Motor Impairment: Participants must exhibit disabling left or right residual arm paresis (\"left\u002Fright arm motor drift\" part of the NIHSS score ≥1).\n* Speech\u002FSwallowing Impairment: Participants must have:\n\n  * Aphasia (AAT-Skala zum Kommunikationsverhalten score ≤3), and\u002For\n  * Dysphagia (MUCCS-N score ≥2).\n* Stable Neurological Status: No relevant changes in neurological status in the past 4 weeks (self-reported).\n* Motor Function: Participants must be able to raise at least 1 block similar to the ones in Box-and-Block-Test.\n* Cognitive Understanding: Participants must be able to understand basic spoken instructions.\n* Sitting Tolerance: Participants must be able to maintain a sitting position for at least 60 minutes.\n* Willingness to Participate: Participants must be willing to participate in the study and able to understand and sign the informed consent.\n\nExclusion Criteria:\n\n* Cognitive Impairments: Cognitive impairments that, in the investigator's judgment, could limit understanding of task instructions.\n* Stroke Location: Participants with a brainstem and\u002For cerebellar stroke.\n* Previous Stroke: Participants with a previous disabling stroke.\n* Hemi-Neglect: Pronounced hemi-neglect at the last documented therapy visit that limits compliance with treatment intervention (investigator's judgment).\n* Anosognosia: Pronounced anosognosia at the last documented therapy visit that limits compliance with treatment intervention (investigator's judgment).\n* Spasticity: Severe spasticity in the affected limb, resulting in complete rigidity in flexion or extension.\n* Seizure Disorders: Participants with uncontrolled epilepsy (investigator's judgement) or epileptic seizure within the last month.\n* Intracranial Pressure: Known ongoing elevated intracranial pressure.\n* Implanted Medical Devices: Participants with implanted medical devices with contraindication for FES such as pacemakers.\n* Metallic Fragments: Participants with implanted metallic fragments in the extremity planned for FES that would limit the use of functional electrical stimulation (FES).\n* Unhealed Injuries: Unrecovered fractures or skin\u002Ftissue lesions in the FES stimulated extremity.\n* Joint Issues: Ossification, contraction, or stiffness of the wrist joint in the FES stimulated extremity that would limit treatment.\n* Botulinum Toxin: Participants who received botulinum-toxin treatment within 6 weeks prior to study inclusion and\u002For for whom botulinum-toxin treatment is planned during the study duration.\n* Co-morbidities: The following conditions will exclude participation:\n\n  * Chronic Obstructive Pulmonary Disease (Stage IV).\n  * Cardiac insufficiency (NYHA Stage IV).\n  * Severe acute infections.\n  * Significant circulatory disturbances in the stimulated extremity.\n  * Sensory disorders that significantly impair the patient's ability to feel pain or react to unsuitable proprioceptive stimuli.\n  * Any other general medical conditions that, in the investigator's judgment, limit the safety or performance of study procedures (investigator's judgement).\n* Electrical Stimulation Intolerance: Known inability to tolerate cutaneous electrical stimulation.",{"count":58,"type":21},10,[24],"The goal of this neurorehabilitation explorative study is to investigate how a closed-loop Brain-Computer Interface Functional Electrical Stimulation (BCI-FES) therapy, used within the intended purpose for hand rehabilitation, may impact swallowing difficulties (dysphagia) and language disorders (aphasia) in post-stroke patients.",[28,62],"Hemorrhagic Stroke",[64,65,66,67,68],"neurorehabilitation","BCI-FES","chronic stroke","aphasia","dysphagia","RECRUITING","2025-11-25",{"date":72,"type":40},"2025-11-26",{"date":74,"type":40},"2025-06-04",{"date":76,"type":21},"2026-06-30",{"name":46,"class":47},1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":89,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":78},"100578621","innsbruck-health-promotion-program-100578621","NCT06813677","Innsbruck Health Promotion Program","INNHEALTH","Inclusion Criteria:\n\n* Signed informed consent of subject\n* Main area of residence in Innsbruck and Innsbruck-Land\n\nExclusion Criteria:\n\n* People who are suspended upon a court order or upon other legal processes or are accommodated according ot the Hospitalization Act, or for whom a custodian is appointed (or appointment is inititated)\n* Persons with impaired power of judgement\n* Persons who are currently engaged in military or community service",true,{"count":88,"type":21},1000,[24],"The primary goal of this single-centre. single-arm, unblinded, pre-post interventional study is to evaluate whether a one-time health assessment and intervention affects the overall vascular health evaluated through the Life's Essential 8 overall vascular health score.\n\nSecondary goals of this study are, among others:\n\n* to describe incidence and prevalence of vascular risk-factors and behaviours\n* to explore prevalence and associations of health and disease in the general population with special focus on cardiovascular risk, cardiovascular diseases, markers of vascular health, signs and (prodromal) symptoms of neurodegeneration as well as psychosocial factors\n* to explore the prevalence of hearing disorders in the general population\n* to collect voice and speech samples to identify novel biomarkers that correlate to vascular health and\u002For hearing status",[92],"Assessment of Vascular Health Risk Factors",[94,95,96,97,98,99],"Life's Essential 8","PBMC","Cardiovascular health","Quality of Life","Mitochondrial function","Hearing impairment","2025-11-18",{"date":102,"type":40},"2025-11-19",{"date":104,"type":40},"2025-05-01",{"date":106,"type":21},"2027-03-31",{"name":46,"class":47},{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":115,"targetDuration":117,"studyType":118,"phases":4,"briefSummary":119,"conditions":120,"keywords":123,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":137},"100407238","stroke-card-registry-100407238","NCT04582825","Stroke-Card Registry","STROKE-CARD REGISTRY: Extension of Standard Care in Patients With Ischemic Stroke and Transient Ischemic Attack","Inclusion Criteria:\n\n* Patients with acute ischemic stroke or high-risk TIA (ABCD2-Score ≥ 4 points) treated at the Department of Neurology of each study center within 30 days after onset\n* Age ≥ 18 years\n* Written informed consent\n\nExclusion Criteria:\n\n* Patients living outside the catchment area of the participating centers\n* Patients under law enforcement or within mandatory military service\n* Age \\\u003C 18 years",{"count":116,"type":21},5000,"7 Years","OBSERVATIONAL","Stroke is the second leading cause of death and one of the main contributors to disability. Patients who survive the acute phase of ischemic stroke and those with transient ischemic attack (TIA) are at high risk of subsequent vascular events. Importantly, recurrent strokes are associated with a higher social and economic impact, higher case fatality, and worse clinical outcome than first-ever strokes. The burden of post-stroke complications, residual deficits, and inadequate medical and psychosocial care all contribute to long-term disability and reduced quality of life in these patients. The Department of Neurology of the Medical University Innsbruck undertook the STROKE-CARD trial (NCT02156778) between 2014 and 2018 with follow-up until 2019 to evaluate the efficacy of the Post-Stroke disease-management program STROKE-CARD care. After implementation of STROKE-CARD care, the investigators aim to document the quality of post-stroke care and compare outcome parameters to historical cohorts and the change over time. Furthermore the investigators aim to gain a large data-resource for future research of biomarkers, disease mechanisms, prognosis and imaging mechanisms for R\\&D.",[121,122],"Ischemic Stroke","Transient Ischemic Attack",[124,125,126,127,128],"Stroke secondary prevention","Stroke Risk factors","Biobank","Post-stroke care","Registry","2025-02-28",{"date":131,"type":40},"2025-03-05",{"date":133,"type":40},"2020-12-09",{"date":135,"type":21},"2027-07-31",{"name":46,"class":47},2,""]