[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"VO Health, Inc.\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":53},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":5},"100623223","molecular-indicators-of-systematic-fitness-100623223",false,"NCT07393841","Molecular Indicators of Systematic Fitness","MISFIT","Inclusion Criteria:\n\n* Be ≥18 years old\n* Be able to understand and provide informed consent (English; additional languages may be added via amendment with translated materials)\n* Be willing to complete VO₂max testing, blood draw, and questionnaires.\n* Be able to safely perform maximal\u002Fsymptom-limited exercise testing as determined by: PAR-Q+ screening and investigator review (included as an attachment) and resting vitals screening (heart rate)\n\nExclusion Criteria:\n\n* Conditions that, in the investigator's judgment, or a medical doctor, makes maximal exercise testing unsafe (e.g., unstable cardiovascular symptoms)\n* Contraindications or unwillingness to undergo venipuncture\n* Acute illness (fever, significant respiratory illness) at the time of testing\n* Failure to comply with procedures.",true,"ALL","18 Years",{"count":20,"type":21},250,"ESTIMATED","OBSERVATIONAL","The goal of this study is to characterize associations between cardiorespiratory fitness, as measured by VO₂max\u002FVO₂peak, and blood-based molecular measurements in adults. This is an observational study where research staff measures VO₂max\u002FVO₂peak and collects fasted, resting blood samples on the same day. The main questions it aims to answer are:\n\n1. Can a multi-analyte blood panel accurately predict directly measured VO₂max\u002FVO₂peak?\n2. How do these blood-based features vary across age, sex, and self-reported or documented physical activity profiles?\n3. Are the predictor analytes able to capture changes in VO₂max\u002FVO₂peak caused by a self-directed intervention (e.g., training for a marathon)?\n4. What is the analytic reliability of the predictor biomarkers?",[25,26,27,28,29,30],"Healthy Adult","Fitness Testing","Athlete","Aging","Exercise Physiology","Human Performance",[32,33,34,35,36,37,38,39,40],"VO2peak","VO2max","cardiorespiratory fitness","proteomics","blood biomarkers","cardiovascular health","oxygen transport","exercise performance","functional capacity","RECRUITING","2026-02-02",{"date":44,"type":45},"2026-02-06","ACTUAL",{"date":47,"type":45},"2026-01-05",{"date":49,"type":21},"2028-05-10",{"name":51,"class":52},"VO Health, Inc.","INDUSTRY",""]