[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Vietnam Military Medical University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":79},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100640272","effectiveness-of-live-motile-sperm-sorting-device-on-ivf-outcomes-in-advanced-paternal-age-100640272",false,"NCT07605182","Effectiveness of Live Motile Sperm Sorting Device on IVF Outcomes in Advanced Paternal Age","Evaluation of the Effectiveness of Live Motile Sperm Sorting Device on In Vitro Fertilization Outcomes in Advanced Paternal Age Group","IVF","Inclusion Criteria:\n\n* Male partners aged ≥ 40 years\n* Semen analysis: volume ≥ 1.4 mL, sperm concentration ≥ 6 million\u002FmL, progressive motility (PR) ≥ 20% after 3-5 days of abstinence.\n* Female partners with ≥ 5 mature (MII) oocytes retrieved.\n* Couples undergoing ICSI with PGT-A and elective single embryo transfer (eSET).\n* Willingness to participate and sign informed consent.\n\nExclusion Criteria:\n\n* Azoospermia, surgical sperm retrieval, or use of cryopreserved sperm.\n* Female uterine or ovarian conditions severely affecting IVF outcomes.\n* Use of donor sperm or donor oocytes","ALL","40 Years",{"count":20,"type":21},378,"ESTIMATED","INTERVENTIONAL",[24],"NA","Male infertility contributes significantly to infertility, particularly in advanced paternal age men where sperm DNA fragmentation is increased. Conventional density gradient centrifugation may induce oxidative stress and sperm damage. LensHooke® CA0 is a centrifugation-free sperm sorting device designed to improve sperm quality and reduce DNA fragmentation. This prospective comparative study evaluates the effectiveness of CA0 versus conventional density gradient centrifugation on post-processing sperm quality, DNA fragmentation index, blastocyst formation, euploid embryo rate, and clinical pregnancy outcomes in IVF\u002FICSI cycles involving men aged 40 years or older",[27,28,29],"Male Infertility","Advanced Paternal Age","Assisted Reproductive Technology",[31,32,33,34],"DNA fragmentation","Advanced paternal age","ICSI","LensHooke CA0","NOT_YET_RECRUITING","2026-05-19",{"date":38,"type":39},"2026-05-22","ACTUAL",{"date":41,"type":21},"2026-05-05",{"date":43,"type":21},"2027-12-30",{"name":45,"class":46},"Vietnam Military Medical University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":65,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":47},"100572430","the-impact-of-peep-guided-electrical-impedance-tomography-on-oxygenation-and-pulmonary-mechanics-in-moderate-to-severe-ards-100572430","NCT06733168","The Impact of PEEP-guided Electrical Impedance Tomography on Oxygenation and Pulmonary Mechanics in Moderate-to-severe ARDS","PEEP","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Intubated moderate and severe ARDS according to the New Global Definition (PaO2\u002FFiO2 ≤200 mmHg).\n* Used continuous sedation with or without paralysis.\n\nExclusion Criteria:\n\n* Presence of pneumothorax that is either undrained or newly occurred.\n* Unstable hemodynamics with a mean arterial pressure \\\u003C 60 mmHg and unresponsive to resuscitation measures, and\u002For heart rate \\\u003C 60 bpm.\n* Contraindications for EIT (pacemakers, automatic external defibrillators, cases of chest trauma or recent chest surgery limiting EIT belt application).\n* Pregnancy.\n* Severe neuromuscular disease.","18 Years",{"count":57,"type":21},76,[24],"Acute respiratory distress syndrome (ARDS) in its moderate to severe forms is associated with high mortality. Mechanical ventilation (MV) remains the cornerstone of ARDS management but carries a significant risk of ventilator-induced lung injury (VILI). Positive end-expiratory pressure (PEEP), a fundamental component of MV, is widely utilized in clinical practice; however, optimal PEEP selection for patients with moderate to severe ARDS remains a complex and unresolved challenge. Electrical impedance tomography (EIT), a bedside imaging modality that evaluates regional ventilation distribution, offers a means of individualizing PEEP settings in mechanically ventilated patients. By balancing the competing risks of alveolar overdistension and collapse, EIT facilitates precision in PEEP titration. This study compares the impact of EIT-guided PEEP selection versus the conventional low FiO2-PEEP table on blood oxygenation and pulmonary mechanics.",[61,62,63,64],"Acute Respiratory Syndrome Distress","Positive End-Expiratory Pressure","Mechanical Ventilation","Electrical Impedance Tomography (EIT)",[66,63,62,67,68,69],"Acute respiratory syndrome distress","electrical impedance tomography","blood oxygenation","pulmonary mechanics","RECRUITING","2024-12-09",{"date":73,"type":39},"2024-12-13",{"date":75,"type":39},"2024-08-15",{"date":77,"type":21},"2026-12-30",{"name":45,"class":46},""]