[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Wandercraft\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":198},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,49,69,86,101,131,169],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100634184","self-balancing-personal-exoskeleton-for-sci-wip-100634184",false,"NCT07536386","Self-balancing Personal Exoskeleton for SCI (WIP)","Empowering Mobility in People With Spinal Cord Injury With a Hands-free, Self-balancing Personal Exoskeleton","User inclusion criteria:\n\n* Any gender, age 18 years or older\n* Motor complete or incomplete SCI at any level\n* ≥ 6 months post SCI\n* Able and willing to attend 9 visits to the center, including sessions of training and assessments of one-to-three hours duration\n* Able to read, understand, and provide informed consent.\n* Patients affiliated to a social security system.\n\nUser exclusion criteria:\n\n* Diagnosis of neurological injury other than SCI;\n* Progressive condition that would be expected to result in changing neurological status;\n* Severe concurrent medical disease, illness or condition judged to be contraindicated by the site physician;\n* Unhealed or unstable traumatic or high impact lower extremity fracture of any duration that is, in the clinical judgement of the study physician, exclusionary for standing and walking;\n* Individual with history of osteoporotic fracture and \u002F or pathology or treatment causing secondary osteoporosis.\n* Untreatable severe spasticity judged to be contraindicated by the site physician;\n* Untreated\u002Funcontrolled hypertension, as judged to be contraindicated by the site physician;\n* Unresolved orthostatic hypotension (change from baseline seated BP to a fall in 20mmHg SBP and\u002For fall in 10mmHG DBP and symptoms when standing), or as judged to be contraindicated by the site physician;\n* Open or unhealed skin pressure sores, abrasions, or bruises at any of the contact points of the exoskeleton;\n* Morphological contraindications to the use of the device;\n* Uncorrectable leg length discrepancy over 2 cm (about 0.79 in) when using additional correction tools;\n* Unable to effectively operate the device with a controller, due to functional and\u002For cognitive impairment, evaluated based on the ability to manipulate the joystick in all direction, press and identify buttons on the controller.\n* Improper fitting in the device;\n* Psychopathology documentation in the medical record that may conflict with study objectives;\n* Pregnancy or women who plan to become pregnant during the study period;\n* Concurrent participation in another interventional trial;\n* Uncontrolled autonomic dysreflexia;\n* Ventilator use at the time of the exoskeleton use.\n* Patient under legal protection.\n\nCompanion inclusion criteria\n\n* Any gender, age 18 years or older.\n* Willingness to attend 9 to 10 visits to the center, including sessions of training and assessments of one-to-three hours duration with the SCI user.\n* Able to read, understand and provide informed consent.\n\nCompanion exclusion criteria:\n\n* Inability to communicate due to cognitive and language disorders;\n* Any disease, concomitant injury, or condition that interferes with the performance or interpretation of the protocol- specified assessments;\n* Insufficient strength and performance capability, evidenced by the ability to hold and retain the device in case of unbalance\u002Ffall;\n* Insufficient availability to complete the study;\n* Concurrent participation in another interventional trial.","ALL","18 Years",{"count":19,"type":20},10,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).",[26,27],"Spinal Cord Injuries","Paraplegia and Tetraplegia",[29,30,31,32,33,34,35],"Spinal Cord Injury","Robotics","Community use","Hands-free exoskeleton","Overground exoskeleton","Walking","Self-balancing","RECRUITING","2026-04-10",{"date":39,"type":40},"2026-04-17","ACTUAL",{"date":42,"type":40},"2026-02-10",{"date":44,"type":20},"2026-04-30",{"name":46,"class":47},"Wandercraft","INDUSTRY",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":14,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":24,"conditions":59,"keywords":60,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":48},"100610011","self-balancing-personal-exoskeleton-for-sci-winy-100610011","NCT07222033","Self-balancing Personal Exoskeleton for SCI (WINY)","SCI user inclusion Criteria:\n\n* Any gender, age 18 years or older;\n* Motor complete or incomplete SCI with lesions at or above T6;\n* ≥ 6 months post SCI;\n* Able and willing to attend 9 to 10 visits1 to the center, including sessions of training and assessments of one-to-three hours duration;\n* Able to read, understand, and provide informed consent;\n* Living in the US and speaks English.\n\nSCI user exclusion Criteria:\n\n* Diagnosis of neurological injury other than SCI;\n* Progressive condition that would be expected to result in changing neurological status;\n* Severe concurrent medical disease, illness or condition judged to be contraindicated by the site physician;\n* Unhealed or unstable traumatic or high impact lower extremity fracture of any duration that is, in the clinical judgement of the study physician, exclusionary for standing and walking;\n* Knee (proximal tibia and\u002For distal femur) BMD \\\u003C0.60 gm\u002Fcm2;\n* Total hip BMD T-scores \\\u003C -3.5;\n* Fragility, minimal trauma, or low impact fracture of the lower extremity since SCI;\n* Untreatable severe spasticity judged to be contraindicated by the site physician;\n* Untreated\u002Funcontrolled hypertension, as judged to be contraindicated by the site physician;\n* Unresolved orthostatic hypotension (change from baseline seated BP to a fall in 20mmHg SBP and\u002For fall in 10mmHG DBP and symptoms when standing), or as judged to be contraindicated by the site physician;\n* Open or unhealed skin pressure sores, abrasions, or bruises at any of the contact points of the exoskeleton;\n* Morphological contraindications to the use of the device;\n* Uncorrectable leg length discrepancy over 2 cm (about 0.79 in) when using additional correction tools;\n* Unable to effectively operate the device with a hand-control interface, due to functional and\u002For cognitive impairment, evaluated based on the ability to manipulate the joystick in all direction, press and identify buttons on the hand control interface.\n* Improper fitting in the device;\n* Psychopathology documentation in the medical record that may conflict with study objectives;\n* Pregnancy or women who plan to become pregnant during the study period;\n* Concurrent participation in another interventional trial;\n* History of uncontrolled autonomic dysreflexia;\n* Presence colostomy and\u002For urostomy;\n* Ventilator use at the time of the exoskeleton use;\n\nCompanion inclusion Criteria:\n\n* Any gender, age 18 years or older;\n* Willingness to attend 9 to 10 visits to the center, including sessions of training and assessments of one-to-three hours duration with the SCI user;\n* Able to read, understand and provide informed consent;\n* Living in the US and speaks English.\n\nCompanion exclusion Criteria:\n\n* Inability to communicate with an assistant due to cognitive and language disorders;\n* Any disease, concomitant injury, or condition that interferes with the performance or interpretation of the protocol- specified assessments;\n* Insufficient strength and performance capability, evidenced by the ability to hold and retain the device in case of unbalance\u002Ffall;\n* Insufficient availability to complete the study;\n* Concurrent participation in another interventional trial.",true,{"count":57,"type":20},12,[23],[29,27],[29,30,31,32,33,34,35],"2026-01-29",{"date":63,"type":40},"2026-02-02",{"date":65,"type":40},"2025-08-11",{"date":67,"type":20},"2026-05-31",{"name":46,"class":47},{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":14,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":55,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":24,"conditions":78,"keywords":80,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":81,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":85,"locationsCount":48},"100578647","self-balancing-personal-exoskeleton-for-sci-site-2-100578647","NCT06814015","Self-balancing Personal Exoskeleton for SCI (Site 2)","SCI user inclusion Criteria:\n\n* Any gender, age 18 years or older;\n* Motor complete or incomplete SCI with lesions at or above T6;\n* ≥ 6 months post SCI;\n* Able and willing to attend 9 to 10 visits1 to the center, including sessions of training and assessments of one-to-three hours duration;\n* Able to read, understand, and provide informed consent;\n* Living in the US and speaks English.\n\nSCI user exclusion Criteria:\n\n* Diagnosis of neurological injury other than SCI;\n* Progressive condition that would be expected to result in changing neurological status;\n* Severe concurrent medical disease, illness or condition judged to be contraindicated by the site physician;\n* Unhealed or unstable traumatic or high impact lower extremity fracture of any duration that is, in the clinical judgement of the study physician, exclusionary for standing and walking;\n* Knee (proximal tibia and\u002For distal femur) BMD \\\u003C0.60 gm\u002Fcm2;\n* Total hip BMD T-scores \\\u003C -3.5;\n* Fragility, minimal trauma, or low impact fracture of the lower extremity since SCI;\n* Untreatable severe spasticity judged to be contraindicated by the site physician;\n* Untreated\u002Funcontrolled hypertension, as judged to be contraindicated by the site physician;\n* Unresolved orthostatic hypotension (change from baseline seated BP to a fall in 20mmHg SBP and\u002For fall in 10mmHG DBP and symptoms when standing), or as judged to be contraindicated by the site physician;\n* Open or unhealed skin pressure sores, abrasions, or bruises at any of the contact points of the exoskeleton;\n* Morphological contraindications to the use of the device;\n* Uncorrectable leg length discrepancy over 2 cm (about 0.79 in) when using additional correction tools;\n* Unable to effectively operate the device with a hand-control interface, due to functional and\u002For cognitive impairment, evaluated based on the ability to manipulate the joystick in all direction, press and identify buttons on the hand control interface.\n* Improper fitting in the device;\n* Psychopathology documentation in the medical record that may conflict with study objectives;\n* Pregnancy or women who plan to become pregnant during the study period;\n* Concurrent participation in another interventional trial;\n* History of uncontrolled autonomic dysreflexia;\n* Presence colostomy and\u002For urostomy;\n* Ventilator use at the time of the exoskeleton use;\n* Insufficient strength and performance capability (the ability to transfer into\u002Fout of the device or perform other training tasks with assistance).\n\nCompanion inclusion Criteria:\n\n* Any gender, age 18 years or older;\n* Willingness to attend 9 to 10 visits to the center, including sessions of training and assessments of one-to-three hours duration with the SCI user;\n* Able to read, understand and provide informed consent;\n* Living in the US and speaks English.\n\nCompanion exclusion Criteria:\n\n* Inability to communicate with an assistant due to cognitive and language disorders;\n* Any disease, concomitant injury, or condition that interferes with the performance or interpretation of the protocol- specified assessments;\n* Insufficient strength and performance capability, evidenced by the ability to hold and retain the device in case of unbalance\u002Ffall;\n* Insufficient availability to complete the study;\n* Concurrent participation in another interventional trial.",{"count":76,"type":20},24,[23],[79,27],"Spinal Cord Injuries (SCI)",[29,30,31,32,33,34,35],{"date":63,"type":40},{"date":83,"type":40},"2025-03-31",{"date":67,"type":20},{"name":46,"class":47},{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":14,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":55,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":21,"phases":93,"briefSummary":24,"conditions":94,"keywords":95,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":96,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":100,"locationsCount":48},"100575845","self-balancing-personal-exoskeleton-for-sci-100575845","NCT06777576","Self-balancing Personal Exoskeleton for SCI","SCI user inclusion Criteria:\n\n* Any gender, age 18 years or older;\n* Motor complete or incomplete SCI with lesions at or above T6;\n* ≥ 6 months post SCI;\n* Able and willing to attend 9 to 10 visits1 to the center, including sessions of training and assessments of one-to-three hours duration;\n* Able to read, understand, and provide informed consent;\n* Living in the US and speaks English.\n\nSCI user exclusion Criteria:\n\n* Diagnosis of neurological injury other than SCI;\n* Progressive condition that would be expected to result in changing neurological status;\n* Severe concurrent medical disease, illness or condition judged to be contraindicated by the site physician;\n* Unhealed or unstable traumatic or high impact lower extremity fracture of any duration that is, in the clinical judgement of the study physician, exclusionary for standing and walking;\n* Knee (proximal tibia and\u002For distal femur) BMD \\\u003C0.60 gm\u002Fcm2;\n* Total hip BMD T-scores \\\u003C -3.5;\n* Fragility, minimal trauma, or low impact fracture of the lower extremity since SCI;\n* Untreatable severe spasticity judged to be contraindicated by the site physician;\n* Untreated\u002Funcontrolled hypertension, as judged to be contraindicated by the site physician;\n* Unresolved orthostatic hypotension (change from baseline seated BP to a fall in 20mmHg SBP and\u002For fall in 10mmHG DBP and symptoms when standing), or as judged to be contraindicated by the site physician;\n* Open or unhealed skin pressure sores, abrasions, or bruises at any of the contact points of the exoskeleton;\n* Morphological contraindications to the use of the device;\n* Uncorrectable leg length discrepancy over 2 cm (about 0.79 in) when using additional correction tools;\n* Unable to effectively operate the device with a hand-control interface, due to functional and\u002For cognitive impairment, evaluated based on the ability to manipulate the joystick in all direction, press and identify buttons on the hand control interface.\n* Improper fitting in the device;\n* Psychopathology documentation in the medical record that may conflict with study objectives;\n* Pregnancy or women who plan to become pregnant during the study period;\n* Concurrent participation in another interventional trial;\n* History of uncontrolled autonomic dysreflexia;\n* Presence colostomy and\u002For urostomy;\n* Ventilator use at the time of the exoskeleton use.\n\nCompanion inclusion Criteria:\n\n* Any gender, age 18 years or older;\n* Willingness to attend 9 to 10 visits to the center, including sessions of training and assessments of one-to-three hours duration with the SCI user;\n* Able to read, understand and provide informed consent;\n* Living in the US and speaks English.\n\nCompanion exclusion Criteria:\n\n* Inability to communicate with an assistant due to cognitive and language disorders;\n* Any disease, concomitant injury, or condition that interferes with the performance or interpretation of the protocol- specified assessments;\n* Insufficient strength and performance capability, evidenced by the ability to hold and retain the device in case of unbalance\u002Ffall;\n* Insufficient availability to complete the study;\n* Concurrent participation in another interventional trial.",{"count":76,"type":20},[23],[79,27],[29,30,31,32,33,34,35],{"date":63,"type":40},{"date":98,"type":40},"2025-02-12",{"date":67,"type":20},{"name":46,"class":47},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":21,"phases":110,"briefSummary":113,"conditions":114,"keywords":118,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":48},"100609911","phase-1-safety-and-feasibility-of-a-self-balancing-exoskeleton-for-rehabilitation-in-the-thoracic-surgical-intensive-care-unit-a-pilot-trial-100609911","NCT07220733","Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial","HEART","Inclusion Criteria:\n\n* Above age of 18 years old,\n* Having undergone thoracic surgery that necessitated admission in the TSICU.\n* Debilitated as defined as a JH-HLM score of 5 or less\n\nExclusion Criteria:\n\n* Height \\\u003C 6'3 feet or weight \\> 220 lbs restrictions\n* Severe muscular spasticity of the lower extremities (Modified Ashworth Scale Grade 3 higher).\n* Current fractures or incomplete bone junctions in the spine, pelvis, and\u002For lower extremities\n* Osteoporosis or lower bone mineral density -3.5, and history(ies) of osteoporotic fracture(s).\n* Skin disorders including Stage I pressure injuries at the hip, lower limbs, and Exoskeleton contact areas, according to the National and European Pressure Ulcer Classification System (NPUAP-EPUAP).\n* Severe arthritis, acute arthritis, or synovitis after total or partial lower limb joint replacement.\n* Myocardial infarction or angina or ischemic heart disease within the last 6 months.\n* Uncorrectable leg length discrepancy over 2 cm when using additional correction tools.\n* III-IV spine scoliotic deformity.\n* Amputations and lower limb prostheses.\n* Pregnancy\n* Adults who lack the capacity to provide informed consent\n* Cardiovascular instability as indicated by:\n* Presence of unstable ventricular or atrial arrhythmias\n* HR \\\u003C 40 or HR \\> 140\n* Lactate \\> 4.0 mmol\u002FL\n* On moderate-high dose vasopressors\u002Finotropes\n* Currently on VA ECMO\n* Respiratory instability as indicated by:\n* FiO2 \\> 0.6\n* PEEP \\> 12 cm H2O\n* RR \\> 35 bpm\n* Currently on VV-ECMO\n* Unable to follow commands\n* Has bed rest orders",{"count":109,"type":20},5,[111,112],"PHASE1","PHASE2","Patients admitted to the Intensive Care Unit (ICU) after thoracic surgery often experience complications related to immobility, such as muscle weakness, pulmonary issues, and longer recovery times. Early mobilization has been shown to improve outcomes, but its implementation is often limited by patient fragility and staff resources.\n\nThis study will test the safety and feasibility of using the Atalante X, a self-balancing exoskeleton, in the Thoracic Surgical ICU at Brigham and Women's Hospital. The exoskeleton is designed to support patients in standing and walking, even if they have limited strength or balance, thereby reducing the physical burden on healthcare staff and increasing patient mobility.\n\nEligible participants are adults recovering from thoracic surgery, who are debilitated (Johns Hopkins Highest Level of Mobility scale ≤ 5). Each participant will undergo up to 2-3 exoskeleton sessions per week for a maximum of 2 weeks. Sessions will be personalized, with progressive standing time and walking depending on patient tolerance.\n\nThe primary goal is to evaluate the safety of exoskeleton use, measured by adverse events such as skin lesions, cardiovascular instability, or accidental device-related issues.\n\nThe secondary goals are to evaluate:\n\nFeasibility (ability to deliver sessions as planned, duration of standing\u002Fwalking, level of assistance needed),\n\nUsability (patient and staff satisfaction, ease of donning\u002Fdoffing, staff workload), and\n\nPreliminary effectiveness (improvement in mobility scores at discharge).\n\nResults will provide early insights into whether robotic exoskeletons can be safely integrated into ICU rehabilitation programs after thoracic surgery.",[115,116,117],"Critical Illness","Post Operative Complication","Thoracic Surgery",[117,119,120,121,122],"Postoperative Care","Atalante X Exoskeleton","Early Mobilisation","Intensive Care Unit (ICU)","2025-10-22",{"date":125,"type":40},"2025-10-24",{"date":127,"type":20},"2025-10",{"date":129,"type":20},"2026-02",{"name":46,"class":47},{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":135,"acronym":136,"eligibilityCriteria":137,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":138,"targetDuration":4,"studyType":21,"phases":140,"briefSummary":141,"conditions":142,"keywords":152,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":109},"100524306","effects-of-atalante-exoskeleton-on-gait-recovery-in-non--or-poorly-ambulatory-patients-with-hemiparesis-in-the-acutesubacute-phase-month-1-to-4-100524306","NCT06107010","Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute\u002FSubacute Phase (Month 1 to 4)","EarlyExo","Inclusion Criteria:\n\n* \\>18 years old\n* First clinically significant disability due to stroke\n* Hemiparesis in acute-subacute phase (1 to 4 months since lesion) due to a stroke\n* Functional Ambulation Category score (FAC) \\\u003C2\n* Patient with health insurance\n* Informed and willing to sign an informed consent form approved by the Ethics Committee. For clarity, if a motor impairment prevents the subject from signing by himself, he\u002Fshe can still be included if the signature can be done by an impartial witness.\n\nExclusion Criteria:\n\n* Muscle overactivity in hip adductors, hamstrings, quadriceps and plantar flexors, which interferes with exoskeleton use, based on clinician investigator's opinion\n* Recent fracture (\\\u003C 3 months) or any therapy inducing secondary osteoporosis\n* Excessive joint mechanical pain in the lower limbs based on clinician investigator's opinion\n* Pressure sore grade I or more over contact zones with Atalante system, according to the International Pressure Ulcer Classification System NPUAP - EPUA\n* Medical contra-indication to medium intensity physical strain\n* Orthostatic hypotension (loss of \\> 20 mmHg systolic BP after 3 minutes in standing position)\n* Uncontrolled seizures\n* Morphological contra-indications to the use of Atalante (as per user's manual)\n* Pregnant woman\n* Adults who lack the capacity to provide informed consent, and all those persons deprived of their liberty in prisons or other places of detention\n* Concurrent participation in another interventional trial",{"count":139,"type":20},66,[23],"The present clinical investigation - EarlyExo, is an interventional, international, multicentric, prospective, single-blinded randomized controlled trial.\n\nThis clinical investigation is designed to test the hypothesis that early and intense introduction of walking sessions assisted by the Atalante exoskeleton, in a sample of hemiparetic patients with still non or poor ambulatory capacities (FAC 0 or 1) between one- and four-months post stroke, would result in a better recovery of functional walking compared to a control group only receiving conventional therapy. Improved recovery will be measured through the proportion of patients reaching a FAC score of 4 or higher at the end of the intervention period. The tested hypothesis is that this proportion will be higher in the Exo group.\n\nThe duration of the intervention period in both groups is 6 weeks.\n\n* For the Exo group: 3 sessions per week (i.e., 18 one-hour sessions) with the Atalante device and 2 sessions per week (i.e., 12 one-hour sessions) of conventional therapy.\n* For the Control group: 5 sessions per week of conventional therapy (i.e., 30 one-hour sessions).\n\nThe study will include 66 patients (33 in each arm) and takes place in two French centers, two German centers and one Spanish center.",[143,144,145,146,147,148,149,150,151],"Stroke, Acute","Stroke, Ischemic","Stroke, Subacute","Stroke Hemorrhagic","Cerebrovascular Disorders","Cerebrovascular Accident","Hemiparesis","Hemiparesis;Poststroke\u002FCVA","Hemiparesis\u002FHemiplegia (One Sided Weakness\u002FParalysis)",[30,153,154,155,156,157,158,159,160],"Rehabilitation","Powered Exoskeleton","Walking recovery","Stroke","Acute stroke","Subacute stroke","Functional Ambulation Category","Randomized controlled study","2025-01-30",{"date":163,"type":40},"2025-02-04",{"date":165,"type":40},"2023-06-12",{"date":167,"type":20},"2026-02-28",{"name":46,"class":47},{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":173,"acronym":174,"eligibilityCriteria":175,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":176,"targetDuration":4,"studyType":21,"phases":178,"briefSummary":179,"conditions":180,"keywords":185,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":48},"100557504","adherence-to-long-term-exoskeleton-rehabilitation-to-treat-lower-limb-weakness-and--or-deficiencies-in-adult-population-100557504","NCT06538974","Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and \u002F or Deficiencies in Adult Population","ALERT","Inclusion Criteria:\n\n* Patient suffering from lower limb weaknesses and \u002F or deficiencies regardless of the cause\n* Adult patient ≥18 years old\n* Patient able to read and write in French and who have signed an informed consent form\n* Patient affiliated to a social security system.\n\nExclusion Criteria:\n\n* Individual with severe spasticity of adductor muscles, hamstring, quadriceps and triceps surae. Severe spasticity is defined by a score of 4 on the modified Ashworth scale\n* Pregnant woman\n* Individual with history of osteoporotic fracture and \u002F or pathology or treatment causing secondary osteoporosis\n* Pressure Ulcer of Grade I or higher according to the NPUAP International Pressure Ulcer Classification System- EPUAP, in areas of contact with the Atalante X system\n* Severe aphasia limiting ability to express needs or to fulfil questionnaires, at the discretion of the physician.\n* Patient with a cardiac or respiratory contraindication to physical exertion, at discretion of the physician\n* Patient unable to deliver his\u002Fher consent\n* Patient under legal protection\n* Patient participating at the same time in another study\n* Patients with morphological contraindications to the use of the Atalante X exoskeleton (as per user's manual) with exceptions as follows: knee flessum of 20° authorized if sensibility is present; equinus of the ankle of 20° allowed regardless of presence or absence of sensibility, hip flessum of 20° allowed regardless of presence or absence of sensibility.",{"count":177,"type":20},100,[23],"In 2019, approximately 2.4 billion people worldwide required rehabilitation for various health pathologies, a 63% increase since 1990. It has been suggested that current rehabilitation frameworks (inpatient, outpatient, and community-based) are insufficient to meet local population needs due to issues like long waiting times, lack of facilities, prioritization, funding, and accessibility.Patients with lower limb weaknesses, resulting from various conditions (for example stroke, traumatic brain injury, spinal cord injury and others) require long-term management and motivation for engagement, which are crucial for functional outcomes. This highlights the need for sustainable gait and balance rehabilitation.\n\nNew technologies like exoskeletons have shown promising results in short-term inpatient programs, improving gait, balance, and quality of life, however, long-term follow-up data are still needed.\n\nThe present clinical investigation is a national, prospective, open-label interventional trial, proposing a 12-month outpatient rehabilitation program with the Atalante X exoskeleton to treat lower limb weakness and\u002For impairments in 100 participants. The rehabilitation program consists of at least one exoskeleton rehabilitation session per week. At the end of the first-year experimental phase, participants can continue for an additional year in the voluntary phase. The program aims to explore the potential long-term effects of supervised robotic rehabilitation on motor, cognitive, bowel, bladder functions, quality of life, and well-being. Assessments are conducted at baseline, after 4 and 12 months of exoskeleton rehabilitation, and at 16 and 24 months for participants in the voluntary phase.",[181,182,183,26,184,148],"Motor Disorders","Gait Disorders, Neurologic","Neurodegenerative Diseases","Weakness, Muscle",[186,187,188,189,153],"Hands-free Exoskeleton","Atalante X","Gait","Balance","2024-07-31",{"date":192,"type":40},"2024-08-06",{"date":194,"type":40},"2023-02-16",{"date":196,"type":20},"2027-07-02",{"name":46,"class":47},""]