[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Western Norway University of Applied Sciences\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":139},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,50,81,111],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100636991","beetroot-juice-a-natural-aid-for-boosting-the-health-benefits-of-exercise-in-post-menopausal-women-100636991",false,"NCT07572877","Beetroot Juice: a Natural Aid for Boosting the Health Benefits of Exercise in Post-menopausal Women?","BEETBOOST","Inclusion Criteria:\n\n* Self-reported biological female and postmenopausal (≥12 months of amenorrhea)\n* Aged 50-70 years\n* Body mass index (BMI) 25-39.9 kg\u002Fm²\n* No contraindications to exercise\n* Physically inactive (\\\u003C150 minutes\u002Fweek of moderate-intensity activity)\n* Able to walk on a treadmill and ambulate without limitations\n* Adequate proficiency in Norwegian to complete questionnaires\n* Willingness and ability to comply with the study schedule and visits\n\nExclusion Criteria:\n\n* Known allergy to nitrates or beetroot juice\n* Current smoker or use of nicotine\u002Ftobacco products\n* Resting blood pressure \\\u003C90\u002F60 mmHg\n* Hypertension greater than stage II (≥160\u002F100 mmHg, ESH criteria)\n* Use of prescription medications affecting heart rate (e.g., systemic β-adrenergic blockers) or nitrate availability (e.g., nitrates, proton pump inhibitors)\n* History of cardiovascular disease (e.g., myocardial infarction, stroke, ischemic heart disease, peripheral artery disease, valvular disease, or aortic aneurysm)\n* Symptoms suggestive of heart disease (e.g., chest pain or dyspnea)\n* Major metabolic disease (e.g., type 1 or type 2 diabetes) or thyroid disorders\n* Recent cancer diagnosis or treatment (within the past 5 years)\n* Significant orthopedic limitations or other contraindications to exercise\n* Diagnosed cognitive impairment\n* Planned travel or elective surgery that would interfere with adherence to the intervention\n* Psychological or social factors that may interfere with study participation\n* Residing beyond a reasonable distance from the study site (logistical constraints)","FEMALE","50 Years","70 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","Menopause and ageing bring several changes to women's health, partly due to a decline in the hormone estrogen. This reduction affects multiple systems in the body, including muscles and bones, and also influences the production of nitric oxide, a molecule that plays a key role in regulating blood flow and blood pressure. An reduced ability to produce nitric oxide is associated with higher blood pressure and an increased risk of cardiovascular and metabolic diseases.\n\nMany women also experience lower levels of physical activity and changes in body composition during midlife, such as increased body fat and reduced muscle mass and strength, which may further decrease exercise capacity.\n\nThis PhD project investigates whether a simple, natural strategy, combining exercise with beetroot juice, can help postmenopausal women achieve greater benefits from exercise. Beetroot juice is naturally rich in nitrates, which the body can convert into nitric oxide, thereby enhancing blood flow. Exercise itself also stimulates nitric oxide production, and together these approaches may have additive or even synergistic effects.\n\nThe study examines whether consuming beetroot juice before exercise can enhance training adaptations and health outcomes in postmenopausal women. Key outcomes include cardiovascular function, body composition, musculoskeletal function, and aerobic capacity.\n\nSome evidence suggests that beetroot juice may amplify the body's response to exercise, which could be particularly beneficial for postmenopausal women, who often face greater barriers to physical activity. By exploring this combined approach, the project aims to evaluate a safe, non-pharmacological strategy to improve physical function and overall health in women after menopause.",[27],"Post-menopause",[29,30,31,32,33,34,35,36],"exercise","beetroot juice","strength training","endurance training","cardiometabolic health","muscleskeletal function","exercise performance","body composition","RECRUITING","2026-05-11",{"date":40,"type":41},"2026-05-13","ACTUAL",{"date":43,"type":41},"2026-02-11",{"date":45,"type":21},"2033-01-01",{"name":47,"class":48},"Western Norway University of Applied Sciences","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},"100626010","a-pilot-study-on-the-safety-of-active-conservative-management-of-low-grade-lumbar-stress-reactions-in-adolescent-soccer-players-100626010","NCT07430072","A Pilot Study on the Safety of Active Conservative Management of Low Grade Lumbar Stress Reactions in Adolescent Soccer Players","ActiveBack","Inclusion Criteria:\n\n* Age: 14-19.\n* Soccer players\n* Low grade (1-2) lumbar stress reaction in L4 or L5.\n* Pain in the area of the affected vertebrae with sports activity and\u002For ADL.\n\nExclusion Criteria:\n\n* Not able to get MRI,\n* Other conditions\u002Finjuries that potentially could affect the result (at baseline and during follow up), i.e. lumbar disc prolapse, scheurmans disease, ankylosing spondylitis,\n* Disorders influencing growth.\n* Previously unsuccessful treatment of lumbar stress reaction.","ALL","14 Years","19 Years",{"count":61,"type":21},40,[24],"Introduction: The Background\n\n* Prevalence: Low back pain (LBP) is very common in young athletes, and lumbar spondylolysis (an overuse injury of bones in the low back) is the leading cause. In adolescent male soccer players with LBP, almost half (up to 48%) have this specific injury.\n* The Current Standard: Existing Norwegian guidelines mandate a break from all sports for a minimum of 3 months when rehabilitating spondylolysis\n* The Challenge: These strict guidelines lack strong evidence from clinical trials and can lead to negative social and physical consequences for the athlete, including exclusion from team activities and reduced general physical activity.\n\nAIM: The Goal of the Study To determine the safety and effectiveness of a newly developed, 4-phased, pain-controlled rehabilitation protocol that uses early, criteria-based activity progression (based on functional capacity and pain levels) for youth football players diagnosed with spondylolysis.\n\nMethod: Study Design and Measurements\n\n* Design: This is a pilot study (prospective cohort study) involving 30-40 youth football players with a first-time diagnosis of low grade (1-2) spondylolysis.\n* Diagnosis: The injury is confirmed using an MRI scan (specifically the VIBE sequence).\n* Data Collection: We will gather data through:\n\n  * MRIs: Comparing images at baseline (start) and after 3 months.\n  * Standardized Clinical Examinations.\n  * PROMs (Patient-Reported Outcome Measures - standardized questionnaires about function and pain).\n  * Weekly reporting on pain intensity and training volume.\n* Outcome: We will compare the changes in the bone healing seen on the MRI findings between the start and end of the 3-month period, and at six months if applicable.",[65],"Spondylolysis Lumbar",[67,68,69,70],"Spondylolysis","adolescent","MRI","football","NOT_YET_RECRUITING","2026-04-29",{"date":74,"type":41},"2026-05-06",{"date":76,"type":21},"2026-05",{"date":78,"type":21},"2027-02",{"name":47,"class":48},3,{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":57,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":22,"phases":92,"briefSummary":93,"conditions":94,"keywords":99,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":49},"100581488","a-digital-health-intervention-to-promote-self-management-in-patients-with-chronic-obstructive-pulmonary-disease-100581488","NCT06850961","A Digital Health Intervention to Promote Self-management in Patients With Chronic Obstructive Pulmonary Disease","A Digital Health Intervention for Promoting Self-management in Patients With Chronic Obstructive Pulmonary Disease - a Feasibility Study","Inclusion Criteria:\n\n* Clinical diagnosis of Chronic Obstructive Pulmonary Disease\n* Mucus-related issues ≥3 times per week\n* Speak and write Norwegian\n* Ability to independently operate a smartphone and\u002For iPad\n\nExclusion Criteria:\n\n* Severe mental illness\n* Substance abuse that hinder participation in the study","18 Years","90 Years",{"count":91,"type":21},90,[24],"Dyspnea, cough, and chronic mucus hypersecretion are common symptoms in patients with Chronic Obstructive Pulmonary Disease (COPD), which increases risk of infections followed by exacerbations, often leading to hospitalization, disease progression and mortality. This patient group requires lifelong treatment in healthcare. A mobile application was developed to facilitate adherence to evidence-based guidelines for tailored breathing and airway clearance techniques to enhance self-management. The app is only in Norwegian and has a Norwegian name which is \"Pust Deg Bedre\" (PDB). The PDB app is fully developed and tested and can be downloaded for free. The app seems promising as a treatment tool, but has not yet been clinical evaluated. This project aims to 1) explore the feasibility of providing the app for patients with COPD, 2) explore the patients' with COPD experiences with the use of the PDB-app in treating dyspnea and mucus secretion, 3) explore the physiotherapists' experiences with the use of the PDB-app in treating dyspnea and mucus secretion, 4) explore the physiotherapists' experiences with implementing the PDB-app in treatment of patients with COPD, 5) explore the patients' experiences with the education in use of the PDB-app, and 6) At a 6-month follow up: explore the physiotherapists experiences with the usefulness and applicability of PBD-app, and to generally explore their experiences with participating in the project.",[95,96,97,98],"Chronic Obstructive Pulmonary Disease (COPD)","Self-management","Mobile Application","Feasibility Studies",[100,101,102,96,97],"COPD","Digital health intervention","Feasibility","2025-02-24",{"date":105,"type":41},"2025-02-28",{"date":107,"type":41},"2025-01-06",{"date":109,"type":21},"2030-12-31",{"name":47,"class":48},{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":57,"minAge":118,"maxAge":119,"enrollmentInfo":120,"targetDuration":4,"studyType":22,"phases":122,"briefSummary":123,"conditions":124,"keywords":126,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":49},"100546941","digital-follow-up-program-for-people-with-chronic-obstructive-pulmonary-disease-in-primary-healthcare-100546941","NCT06401512","Digital Follow-up Program for People with Chronic Obstructive Pulmonary Disease in Primary Healthcare","A Guided Self-determination Follow-up Program Delivered Within a Digital Platform for People with Chronic Obstructive Pulmonary Disease in Primary Care","Inclusion Criteria:\n\n* Diagnosed with COPD living at home\n* Post-bronchodilator forced expiratory volume 1 s (FEV1) to forced vital capacity (FVC) below lower limit of normality\n\nExclusion Criteria:\n\n* Severe somatic disease\n* Severe psychiatric diagnosis\n* Not able to provide informed consent\n* Do not write, speak or understand Norwegian","35 Years","80 Years",{"count":121,"type":21},80,[24],"Chronic Obstructive Pulmonary Disease (COPD), characterized by non-reversible airflow obstruction, contributes to high mortality and morbidity rates worldwide, including Norway. Individuals with COPD experience symptoms and complications that impede daily activities and diminish their quality of life. COPD places a growing burden on healthcare systems presently and in the future. Interventions to empower individuals to self-manage their health effectively are needed to help the challenges of living with COPD, and work towards a sustainable healthcare system. As part of the broader healthcare policy agenda, this project aligns with the increasing emphasis on digital homebased primary healthcare. The intervention in this study will combine digital homebased care and guided self-determination follow-ups (GSD) within a general practice setting.\n\nThis project consists of 1) explore the feasibility of a COPD specific GSD counselling program delivered within a digital platform in primary care, 2) explore patients' and nurses' experiences applying the program, 3) examine the treatment fidelity of the intervention amongst healthcare professionals.\n\nThis project is a pilot cluster-randomized controlled trial (RCT), including individuals diagnosed with COPD, conducted in primary healthcare settings, and assessment of feasibility and uncertainties before conducting a later full-scale cluster-RCT. The intervention draws upon the Medical Research Council's revised guidelines for developing complex intervention studies, focusing on the initial phases of intervention development and pilot testing. Primary care clinics are randomly assigned into either an intervention- or a control group. The intervention consists of the GSD counselling program with follow-up within a digital platform. The control group provide regular care. The project will include both qualitative (individual semi-structured interviews), and quantitative data (questionnaires and clinical data).\n\nIn conclusion, this project explores an innovative intervention offering personalized strategies for COPD management in primary care clinic, by containing a digitalized homebased care program and follow-ups. The study aims to improve the daily living for people with COPD, while contributing to the future sustainability of healthcare systems.",[125],"COPD Chronic Obstructive Pulmonary Disease",[100,127,128,129,130],"Guided self-determination","Primary healthcare","Randomized controlled trial","Web-based follow-up","2025-01-20",{"date":133,"type":41},"2025-01-23",{"date":135,"type":41},"2024-05-02",{"date":137,"type":21},"2026-12",{"name":47,"class":48},""]