[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Womack Army Medical Center\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":123},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,72,95],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100447860","pre--and-post-neuromusculoskeletal-injury-risk-evaluation-for-return-to-duty-enhancement-100447860",false,"NCT05111925","Pre- and Post-neuromusculoskeletal Injury Risk Evaluation for Return-to-Duty Enhancement","Pre-neuromusculoskeletal Injury Risk Factor Evaluation and Post-neuromusculoskeletal Injury Assessment for Return-to-duty\u002FActivity Enhancement","PREPARE","Inclusion Criteria:\n\nPilot Cohort\n\n* Active duty Service members cleared for full physical activity.\n* 18-44 years old\n\nUninjured Cohorts\n\n* Active duty Service members cleared for full physical activity.\n* 18-44 years old\n\nInjured Cohorts\n\n* Active duty Service members receiving conservative treatment exclusively for a musculoskeletal injury affecting the low back or lower extremity.\n* Recruited at any time following presentation to a rehabilitation care facility for care of the MSKI of interest\n* 18-44 years old\n\nExclusion Criteria:\n\nPilot Cohort\n\n* Currently on limited duty status, for any reason.\n* Unable to read or comprehend the English language.\n* Pregnant females (will be eligible for participation in the study after the pregnancy)\n\nUninjured Cohorts\n\n* Currently on limited duty status, for any reason.\n* Scheduled for a deployment or separation from current unit within the next 12 months.\n* Unable to read or comprehend the English language.\n* Pregnant females (will be eligible for participation in the study after the pregnancy)\n\nInjured Cohorts\n\n* Unable to read or comprehend the English language.\n* A MSKI within the last 6 months.\n* History of lower extremity or low back musculoskeletal related surgery.\n* History of moderate or severe traumatic brain injury.\n* Pregnant females (will be eligible for participation in the study after the pregnancy)",true,"ALL","18 Years","44 Years",{"count":22,"type":23},2690,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to develop comprehensive and efficient pre- and post- musculoskeletal injury (MSKI) risk assessments for Service members, incorporating both objective and subjective measures. This is a multi-site observational study to identify the pre- and post-MSKI physical and psychosocial factors contributing to MSKI risks and undesired patient outcomes following MSKI. The study hypothesis is that a set of field-expedient clinical assessments can identify Service member specific MSKI risk factors and post-MSKI deficits that contribute to undesired patient outcomes and provide data to guide patient-specific risk mitigation and rehabilitation programs.",[27],"Musculoskeletal Injuries",[29,30,31,32,33],"musculoskeletal injury","biomechanics","movement assessment","neuromuscular control","patient reported outcomes","RECRUITING","2026-05-29",{"date":37,"type":38},"2026-06-03","ACTUAL",{"date":40,"type":38},"2022-10-26",{"date":42,"type":23},"2028-05-31",{"name":44,"class":45},"Womack Army Medical Center","FED",2,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":46},"100556606","neurocognitive-ankle-training-for-instability-to-optimize-neuromusculoskeletal-outcomes-nation-100556606","NCT06527287","Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION)","NATION","Inclusion Criteria:\n\n* Physically active and engage in regular exercise\u002Ftraining\n* 18-44 years old (accounts for 86% of the individuals deployed in recent military conflicts)\n* Answer \"yes\" to Question 1 (i.e., have you ever sprained an ankle?) on the Ankle Instability Instrument\n* Answer \"yes\" to any four of the remaining Ankle Instability Instrument questions\n* Score \\\u003C24 on the Cumberland Ankle Instability Tool\n* Report at least two episodes of the ankle \"giving way\" in the last six months\n* Access to a functional email address and internet for completion of health and Service member outcomes\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Unable to read or comprehend the English language.\n* An ankle sprain within the last six (≤6) weeks that resulted in altered or missed physical activity for one or more (≥1) consecutive days.\n* History of ankle surgery.\n* History of lower extremity fracture in the last year or history of fracture that required fixation.\n* Any peripheral neuropathies or other health conditions\u002Fcurrent musculoskeletal injuries that may influence balance.\n* Pregnant females (will be eligible for participation in the study after delivery of the baby and medical clearance by a qualified and licensed healthcare provider).",{"count":55,"type":23},180,"INTERVENTIONAL",[58],"NA","The purpose of this study is to examine the effectiveness of a novel ankle rehabilitation protocol on improving clinical and health outcomes in physically active individuals with chronic ankle instability (CAI). Our central hypothesis is NATION, a novel rehabilitation intervention that includes neurocognitive tasks, will improve overall health and function, and reduce lower extremity musculoskeletal injury in physically active individuals with CAI.",[61],"Chronic Ankle Instability",[63],"Chronic Ankle Instability; neurocognition; evidence-based rehabilitation; musculoskeletal outcomes; dual tasks","2026-04-16",{"date":66,"type":38},"2026-04-22",{"date":68,"type":38},"2025-10-13",{"date":70,"type":23},"2027-06-14",{"name":44,"class":45},{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":56,"phases":81,"briefSummary":82,"conditions":83,"keywords":86,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":46},"100555820","emovi-3d-knee-assessment-device-intervention-for-operational-readiness-100555820","NCT06517056","Emovi 3D Knee Assessment Device Intervention for Operational Readiness","Objective Dynamic and 3D Knee Assessment Medical Device to Improve Recovery and Accelerate Return to Readiness in Service Members With Knee Pain","Inclusion Criteria:\n\n* Age 18-50\n* Active Duty Service Member stationed at Fort Liberty and Schofield Barracks\n* Diagnosis of patellofemoral pain (ICD-10 codes: M25.2 (pain in unspecified knee), M25.561 (pain in right knee), and M25.562 (pain in left knee)\n\nExclusion Criteria:\n\n* Pregnancy\n* Known to be leaving that duty station within next 3 months\n* Concurrent lower limb injuries (examples include but are not limited to ankle sprain or HS strain)\n* Previous knee surgery\n* History of traumatic knee injury, such as a ligament tear or meniscal tear\n* Presence of rheumatoid or neurological disease","50 Years",{"count":55,"type":23},[58],"This is a randomized clinical trial investigating the use of the Emovi Knee Kinesiography information in the treatment of anterior knee pain in physical therapy.",[84,85],"Patellofemoral Pain","Patellofemoral Pain Syndrome",[84,85],"2025-07-10",{"date":89,"type":38},"2025-07-16",{"date":91,"type":38},"2024-10-24",{"date":93,"type":23},"2025-10",{"name":44,"class":45},{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":103,"enrollmentInfo":104,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":106,"conditions":107,"keywords":110,"overallStatus":114,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":4},"100478695","assessment-of-myocarditis-after-replication-deficient-smallpox-immunization-100478695","NCT05513313","Assessment of Myocarditis After Replication-Deficient Smallpox Immunization","Prospective Assessment of Myocarditis After Replication-Deficient Smallpox Immunization","PAMARDSI","Inclusion Criteria:\n\n* Active duty military personnel within the range of 18-45 years of age without limitations to gender or ethnicity.\n* Primary vaccinee (receiving smallpox vaccine for the first time) with a force health protection requirement for the smallpox vaccination\n* Medical screening for immunization completed and potential participant found eligible for immunization (standard of care)\n\nExclusion Criteria:\n\n* Known contraindication to replication deficient smallpox vaccination based on FDA-approved package insert for JYNNEOS™ vaccine.\n* No indication for replication deficient smallpox vaccination based on FDA-approved package insert for JYNNEOS, ACIP or DoD guidelines\n* Secondary smallpox vaccinee (patients who had previously received any smallpox vaccine).\n* Age less than 18 years or age greater than 45 years.\n* Inability to provide informed consent.\n* Presence of a moderate or severe acute illness with or without a fever\n* Pregnancy: We will rely on the subject for an assessment of her pregnancy status, based on answers in the routine adult immunization screening questionnaire. (Screening by history is the current standard of care.)\n* Scheduled deployment, PCS or TDY that would interfere with the respective follow-up visits. (no planned deployment, TDY or PCS for 65 days after enrollment\u002Fvisit 1).","45 Years",{"count":105,"type":23},2350,"This is a prospective observational phase IV study of a novel, replication-deficient smallpox vaccine that has been recently been approved by FDA. The purpose of this study is to determine if there are any abnormalities detected by electrocardiographic testing and\u002For blood tests within 35 days of receiving the second dose of smallpox vaccine either alone or co-administered with other vaccines that may\u002Fmay not be suggestive of myopericarditis.",[108,109],"Myopericarditis","Small Pox",[111,112,113],"Small pox vaccine","ACAM2000™","Dryvax®","NOT_YET_RECRUITING","2023-12-07",{"date":117,"type":38},"2023-12-14",{"date":119,"type":23},"2029-03",{"date":121,"type":23},"2033-10",{"name":44,"class":45},""]