[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Wonkwang University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":143},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,69,96,122],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100642696","personalized-music-dreaming-during-propofol-sedation-100642696",false,"NCT07638072","Personalized Music, Dreaming During Propofol Sedation","Personalized Music Increases Dreaming During Propofol Sedation: A Randomized Trial Comparing Preferred Music, Matched Non-preferred Music, and Silence","Inclusion Criteria:\n\n* Adults aged 19 years or older.\n* Scheduled to undergo an elective procedure under spinal anesthesia or peripheral nerve block with intravenous propofol sedation.\n* American Society of Anesthesiologists physical status I to III.\n* Able to provide written informed consent.\n* Able to wear closed-back headphones during the study period.\n* Able to complete postoperative interviews and study questionnaires.\n\nExclusion Criteria:\n\n* Planned general anesthesia.\n* Severe hearing impairment that would interfere with the auditory intervention.\n* Major psychiatric instability or condition that may interfere with study participation or dream assessment.\n* Expected significant intraoperative bleeding.\n* Inability to complete the required postoperative interviews or questionnaires.\n* Contraindication to propofol or other study sedative agents.\n* Refusal or withdrawal of informed consent.",true,"ALL","19 Years",{"count":20,"type":21},300,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized clinical trial will evaluate whether music delivered through closed-back headphones during intravenous propofol sedation affects dreaming and the overall sedation experience. Adults scheduled for elective procedures under spinal anesthesia or peripheral nerve block with propofol sedation will be randomly assigned to one of three groups: patient-selected preferred music, matched non-preferred music, or silence with identical headphones.\n\nThe main purpose of the study is to determine whether listening to music increases the occurrence of dream recall compared with silence, and whether personally preferred music makes recalled dreams more pleasant than matched non-preferred music. Dream recall and dream pleasantness will be assessed after recovery using a standardized interview. The study will also evaluate dream content, patient satisfaction, sedative and opioid requirements, hemodynamic variability, postoperative pain, nausea and vomiting, recovery time, and adverse events.\n\nThis study is intended to determine whether a simple, low-cost headphone-based music intervention can improve patient-centered quality of propofol sedation without compromising safety.",[27,28],"Procedural Sedation","Dreams",[30,31,32,33,34,35],"Propofol","Sedation","Music","Dreaming","Auditory Stimulation","Patient Experience","RECRUITING","2026-06-24",{"date":39,"type":40},"2026-06-26","ACTUAL",{"date":37,"type":40},{"date":43,"type":21},"2026-08-30",{"name":45,"class":46},"Wonkwang University Hospital","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":63,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":47},"100639017","glp-1-ra-cessation-and-gastric-ultrasound-findings-100639017","NCT07623148","GLP-1 RA Cessation and Gastric Ultrasound Findings","Time-dependent Association Between Cessation of Glucagon-like Peptide-1 Receptor Agonists and Residual Gastric Contents Assessed by Point-of-care Gastric Ultrasound: a Prospective Observational Study","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Patients receiving a glucagon-like peptide-1 receptor agonist.\n* Patients scheduled for elective non-cardiac surgery requiring general anesthesia.\n* Patients able to provide written informed consent.\n\nExclusion Criteria:\n\n* Emergency surgery.\n* History of prior gastric surgery.\n* Known gastroparesis or severe gastroesophageal reflux disease.\n* Declined or unable to provide written informed consent.","65 Years",{"count":57,"type":21},186,"OBSERVATIONAL","This prospective observational study will evaluate the association between the time interval since the last dose of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and residual gastric contents before elective surgery. Adult patients receiving GLP-1 RAs and scheduled for elective non-cardiac surgery under general anesthesia will undergo preoperative point-of-care gastric ultrasound. The study will assess whether longer GLP-1 RA cessation intervals are associated with lower ultrasound-estimated gastric volume and a lower frequency of high-risk gastric contents. Body mass index will also be evaluated as a potential modifier of this association.",[61,62],"Residual Gastric Contents","Delayed Gastric Emptying",{"date":39,"type":40},{"date":65,"type":21},"2026-07-04",{"date":67,"type":21},"2026-08-20",{"name":45,"class":46},{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":77,"conditions":78,"keywords":84,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":91,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":95,"locationsCount":47},"100613000","paired-comparison-of-svv-and-pvi-accuracy-100613000","NCT07260890","Paired Comparison of SVV and PVI Accuracy","Diagnostic Accuracy of Stroke Volume Variation (SVV) vs Pleth Variability Index (PVI) for Predicting Fluid Responsiveness in Laparoscopic Major Abdominal Surgery-A Prospective, Paired, Cohort Study","Inclusion Criteria:\n\n* Age ≥18 years\n* ASA physical status I-III\n* Elective laparoscopic major abdominal surgery under general anesthesia\n* Arterial line in place for clinical care\n* Able to provide informed consent\n* Arterial and plethysmographic waveforms adequate for measurement\n\nExclusion Criteria:\n\n* linically significant arrhythmia (e.g., atrial fibrillation with irregular R-R)\n* Severe valvular heart disease or intracardiac shunt\n* Pregnancy\n* Severe right-heart failure or condition where a fluid bolus is unsafe\n* Ongoing hemodynamic instability requiring rapid vasoactive titration at assessment\n* Persistently unreliable arterial\u002Fpleth signals despite optimization\n* Any situation the anesthesiologist judges that the fluid challenge is unsafe",{"count":20,"type":21},"This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a small fluid bolus will improve the heart's pumping during laparoscopic major abdominal surgery. Adults having elective surgery under general anesthesia will receive two small, timed 250-mL crystalloid infusions as part of routine care (one before and one after creation of the pneumoperitoneum). The research team will record SVV and PVI values just before and three minutes after each infusion while keeping these readings hidden from the clinicians so that usual care is not changed. No experimental drugs or devices are used. The main goal is to learn which index better identifies \"fluid responsiveness,\" so future care can be safer and more consistent. Potential risks are minimal and relate to the small fluid boluses (temporary changes in blood pressure or heart rate); the test stops if the anesthesiologist has any safety concerns. There is no direct benefit to participants, but results may help guide fluid therapy for similar patients in the future. The study is being conducted at a single academic hospital in the Republic of Korea and plans to enroll about 300 adults.",[79,80,81,82,83],"Perioperative Care","Fluid Therapy","Monitoring, Physiologic","Hemodynamics","Laparoscopy",[85,86,87,88,89,90],"stroke volume variation; SVV","Pleth Variability Index; PVI","fluid responsiveness","goal-directed fluid therapy; GDFT","pneumoperitoneum","diagnostic accuracy; ROC; AUROC",{"date":39,"type":40},{"date":93,"type":21},"2026-07-01",{"date":43,"type":21},{"name":45,"class":46},{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":103,"targetDuration":4,"studyType":22,"phases":105,"briefSummary":106,"conditions":107,"keywords":110,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":116,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":47},"100600435","effectiveness-of-hypotension-prediction-index-hpi-in-preventing-hypotension-in-the-post-anesthesia-care-unit-pacu-100600435","NCT07097454","Effectiveness of Hypotension Prediction Index (HPI) in Preventing Hypotension in the Post-Anesthesia Care Unit (PACU)","Effectiveness of Hypotension Prediction Index (HPI) in Preventing Hypotension in the Post-Anesthesia Care Unit (PACU): A Prospective, Randomized, Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 19 years\n* Undergoing elective surgery under general anesthesia\n* Presence of intra-arterial catheter at the end of surgery\n* Expected PACU stay of ≥ 30 minutes\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Immediate postoperative ICU admission\n* Use of vasopressors during emergence from anesthesia\n* ASA physical status classification of V\n* Known contraindications to arterial line placement\n* Participation in another interventional study within 30 days",{"count":104,"type":21},210,[24],"Postoperative hypotension in the post-anesthesia care unit (PACU) is common and linked to adverse outcomes. The Hypotension Prediction Index (HPI) predicts hypotensive events intraoperatively, but its PACU application is unexplored. This study aims to investigate the effectiveness of HPI-guided monitoring in preventing PACU hypotension.",[108,109],"Hypotension","Postoperative Complications",[111,112,113,114,115],"Hypotension Prediction Index (HPI)","PACU","Hemodynamic Monitoring","Arterial Pressure Waveform","HemoSphere",{"date":39,"type":40},{"date":118,"type":21},"2026-07-15",{"date":120,"type":21},"2026-09-11",{"name":45,"class":46},{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":11,"sex":129,"minAge":18,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":133,"conditions":134,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":141,"leadSponsor":142,"locationsCount":47},"100591499","pvi-predictors-in-laparoscopic-hysterectomy-100591499","NCT06981221","PVI Predictors in Laparoscopic Hysterectomy","Predictors of Pleth Variability Index During Laparoscopically Assisted Vaginal Hysterectomy","Inclusion Criteria:\n\n* adult females aged 19-70 years (American Society of Anesthesiologists physical status I-III) scheduled for elective LAVH.\n\nExclusion Criteria:\n\n* emergency surgery, severe cardiac or pulmonary disease, renal failure, pregnancy, or conditions contraindicating fluid administration. Participants were consecutively recruited during preoperative consultations.","FEMALE","70 Years",{"count":132,"type":21},50,"This observational study investigates the predictors of Pleth Variability Index (PVI) changes in euvolemic patients undergoing laparoscopic-assisted vaginal hysterectomy (LAVH). The primary objective is to quantify changes in PVI (ΔPVI) across six intraoperative time points associated with positional shifts. Secondary objectives include identifying key predictors of significant PVI change (ΔPVI ≥ 5%), such as passive leg raising, Trendelenburg position, body mass index (BMI), and intraabdominal pressure. Additional variables including perfusion index, mean arterial pressure, bispectral index, skin temperature, age, and anesthetic agent will be evaluated as potential modulators. Findings aim to support individualized fluid management strategies in LAVH.",[135,136,137],"Hysterectomy","PVI","Fluid Responsiveness",{"date":139,"type":40},"2026-06-29",{"date":93,"type":21},{"date":67,"type":21},{"name":45,"class":46},""]