[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Wrightington, Wigan and Leigh NHS Foundation Trust\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":64},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,37],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":4,"overallStatus":24,"whyStopped":4,"lastUpdateSubmitDate":25,"lastUpdatePostDateStruct":26,"startDateStruct":29,"completionDateStruct":31,"leadSponsor":33,"locationsCount":36},"100536743","a-diagnostic-test-accuracy-study-comparing-biopsy-to-aspiration-in-shoulder-and-elbow-arthroplasty-revision-surgery-base-study-100536743",false,"NCT06268795","A Diagnostic Test Accuracy Study Comparing Biopsy to Aspiration in Shoulder and Elbow Arthroplasty Revision Surgery (BASE Study)","Inclusion Criteria:\n\n* Aged: 18 years or older.\n* A participant is willing and able to give informed consent for participation in the study.\n* Patient undergoing revision shoulder or elbow arthroplasty surgery.\n* Previous anatomic total shoulder arthroplasty (TSA), shoulder hemiarthroplasty (HA), reverse total shoulder arthroplasty (RTSA), total elbow arthroplasty (TEA), distal humeral hemiarthroplasty (DHH) and radial head arthroplasty (RHA).\n\nExclusion Criteria:\n\n* Refusal of consent.\n* Antibiotic treatment was not stopped 2 weeks before aspiration or biopsy.\n* Pregnancy.\n* Part of any other trial with similar interventions unless previously agreed on with investigators.","ALL","18 Years",{"count":18,"type":19},244,"ESTIMATED","OBSERVATIONAL","The aim of this study is to compare the diagnostic accuracy of percutaneous aspiration against open biopsy, using microbiological and histological methods, for the detection of shoulder and elbow periprosthetic joint infection (PJI). This is to establish the utility of pre-operative joint aspiration in the treatment pathway for shoulder and elbow PJI.",[23],"Periprosthetic Joint Infection","RECRUITING","2025-07-23",{"date":27,"type":28},"2025-07-28","ACTUAL",{"date":30,"type":28},"2024-03-20",{"date":32,"type":19},"2028-09-01",{"name":34,"class":35},"Wrightington, Wigan and Leigh NHS Foundation Trust","OTHER",1,{"id":38,"slug":39,"hasResults":11,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":45,"enrollmentInfo":46,"targetDuration":4,"studyType":48,"phases":49,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":24,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":36},"100361346","comparing-injection-treatments-for-tennis-elbow-100361346","NCT03984955","Comparing Injection Treatments for Tennis Elbow","A Prospective, Double Blind, Single Centre, RCT, Comparing the Effectiveness of Physiotherapy in Addition to One of 3 Types of Image Guided Injection of the Common Extensor Tendon, on Pain and Function in Patients With Tennis Elbow.","CITTE","Inclusion Criteria:\n\nInvitations to participate in the study will be extended to male and female patients, 18 years and above, referred to the Orthopaedic Departments who receive a diagnosis of Lateral Epicondyle Tendinosis (with or without degenerative changes) with symptoms present for \\> 3 months, whose symptoms and clinical evaluation warrant the prescription of a peri-tendinous injection to relieve symptoms and who are competent to give informed consent.\n\nExclusion Criteria:\n\n* Absence of tenderness at the lateral epicondyle.\n* Congenital or traumatic bio-mechanical deformities of Elbow complex.\n* Previous Corticosteroidal, Local Anaesthetic, PRP or Hyaluronic Acid injections to target elbow within the last three months.\n* Known hypersensitivity to PRP, Hyaluronic acid or any excipients associated with any of the prescribed injections.\n* Known contraindication to any treatments constituting normal\u002Fappropriate therapy in the view of the Consulting clinician including local infection\n* Ipsilateral arm pathology severe enough to cause confusion of localised pain perception.\n* Pregnant or lactating women\n* Pain score less than 4\u002F10\n* Patients commenced on medication for the treatment of anxiety or depression within the last 6 weeks\n* Previous involved in research in last 12 months\n* Any progressive, degenerative neuromuscular disorder","75 Years",{"count":47,"type":19},123,"INTERVENTIONAL",[50],"NA","Tennis elbow is one of the most common musculoskeletal problems affecting the arm and is thought to be mainly due to overuse of the muscles that extend the wrist. The pain arises from the lateral epicondyle of the humerus, where the tendons of the wrist extensor muscles attach.\n\nThere are many treatment options available for tennis elbow including oral medication, physiotherapy and injection therapy. Surgical options are reserved for those who fail to respond to more conservative treatments. Physiotherapy is a widely used, non-invasive treatment option for the management of tennis elbow. Research has shown that in the longer term, physiotherapy is superior to corticosteroid injection in the treatment of tennis elbow and a meta-analysis of published research concluded that Platelet Rich Plasma injection and Hyaluronic Acid injection are superior to corticosteroid for long term pain relief in tennis elbow.\n\nAt present there is not enough evidence to indicate what the 'Gold Standard' treatment for tennis elbow is, and more research is therefore needed to help guide decision-making. The aim of this study is therefore to examine the effects of injection therapy in addition to physiotherapy treatment, in comparison to physiotherapy and a control injection on pain and function in patients with tennis elbow.\n\nAll participants in this study will undergo a structured, specifically designed, class-based physiotherapy intervention, in addition to being randomly allocated to receive one of the following three types of injection: (a) a control injection whereby a needle is inserted into the skin but no therapeutic substance is injection, (b) a single therapeutic injection of platelet-rich plasm or (c) a single therapeutic injection of hyaluronic acid. Baseline data will be collected at the time of recruitment and participants will be followed up at 3 months and 12 months post treatment. Outcomes will be assessed using various patient-reported outcome measures in addition to clinical examination. The primary outcome for this study is the improvement in the quick DASH score at 12 months post-treatment compared to baseline.",[53,54,55],"Tennis Elbow","Lateral Epicondylitis","Elbows Tendonitis","2024-08-05",{"date":58,"type":28},"2024-08-06",{"date":60,"type":28},"2018-04-18",{"date":62,"type":19},"2026-02-06",{"name":34,"class":35},""]