[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Wu Shangling\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100603932","exercise-andor-hmb-in-older-diabetes-with-low-muscle-mass-100603932",false,"NCT07142941","Exercise and\u002For HMB in Older Diabetes With Low Muscle Mass","Effects of Exercise and\u002For β-hydroxy-β-methylbutyrate Supplementation on Muscle Mass, Physical Performance and Insulin Resistance in Older Diabetes With Low Muscle Mass: a Randomized, Double-blind, Placebo-controlled Trial","Inclusion Criteria:\n\n* Aged 60-80 ;\n* Diagnosis of T2DM\n* Low muscle mass: met a reference value for low muscle mass defined by the Asian Working Group for Sarcopenia (AWGS) criteria with skeletal muscle index \\\u003C5.7 kg\u002Fm2 for women and \\\u003C7.0 kg\u002Fm2 for men\n\nExclusion Criteria:\n\n* Individuals who had an organic disease of the nervous system;\n* Who were restricted from engaging in exercise by a medical doctor;\n* Who was unconscious and unable to complete the questionnaire;\n* Who used other supplementations for muscle mass gain;\n* Who had impaired cardiac, kidney, or liver function.","ALL","60 Years","80 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","The investigators aimed to examine if β-hydroxy-β-methylbutyrate (HMB) supplementation enhances the effects of exercise on muscle mass, physical performance and insulin resistance and observe potential residual effects in older diabetes with low muscle mass, and to find the optimal treatment plan.",[27,28],"Diabetes","Low Muscle Mass",[30,31,32,33],"low muscle mass","diabetes","HMB","exercise","NOT_YET_RECRUITING","2026-03-30",{"date":37,"type":38},"2026-03-31","ACTUAL",{"date":40,"type":21},"2026-04-01",{"date":42,"type":21},"2027-12-31",{"name":44,"class":45},"Wu Shangling","OTHER",""]