[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Yang Jing\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100598959","comparative-study-of-magnetocardiography-and-emission-computed-tomography-100598959",false,"NCT07078266","Comparative Study of Magnetocardiography and Emission Computed Tomography.","Multicenter Comparative Study on the Diagnostic Efficacy of \"Ultra-high Sensitivity\" Cardiomagnetic Detection and Myocardial Nucleoradiology Scanning for Early Diagnosis of Myocardial Ischemia.","Inclusion Criteria:\n\n* Age ≥18 years\n* Presence of myocardial ischemia-related symptoms (e.g., angina pectoris) with suspected CHD or CMVD, scheduled for ECT examination\n* Signed informed consent form\n\nExclusion Criteria:\n\n* Hemodynamic instability (systolic blood pressure \\\u003C90 mmHg or requiring vasoactive drugs);\n* Cardiac arrhythmias, including ventricular tachycardia, ventricular fibrillation, severe sinus bradycardia and sinus pauses, and second - degree or higher - degree atrioventricular block and other severe arrhythmias;\n* Aortic dissection aneurysm, severe aortic valve stenosis or insufficiency;\n* Elderly or frail patients with neuromuscular or osteoarticular diseases who cannot complete exercise stress ECT; Allergy to drugs used in pharmacologic stress ECT;\n* Patients with severe renal insufficiency with an estimated glomerular 6.filtration rate (eGFR) \\\u003C 30 ml\u002Fmin or those undergoing dialysis;\n* Patients with malignant tumors and a life - expectancy of less than1 year;\n* Pregnant or lactating women;\n* Patients unable to undergo MCG examination due to inability to enter the chamber, metallic implant interference, or other conditions deemed unsuitable by researchers.","ALL","18 Years",{"count":19,"type":20},218,"ESTIMATED","1 Month","OBSERVATIONAL","Coronary atherosclerotic heart disease (CHD) and Coronary Microvascular Disease (CMVD), as the primary etiologies of myocardial ischemia, have garnered increasing clinical attention due to their high prevalence and severe prognostic implications.\n\nCurrently, the primary method for detecting myocardial ischemia is Emission Computed Tomography (ECT). However, it suffers from limitations such as low spatial resolution and radiation exposure risks.magnetocardiography(MCG) is a non-invasive, contactless medical imaging device that maps localized magnetic signals generated by cardiac electrical activity.The magnetocardiography (MCG) system constructs cardiac magnetic field images by recording biomagnetic signals via a multi-channel sensor array positioned above the thoracic region.MCGcan capture the spatial magnetic field changes of ischemic myocardial cells, and carry out early warning, early diagnosis and positioning detection of myocardial ischemia.\n\nThis study is a prospective, multicenter, controlled trial. The study will enroll adult patients presenting with myocardial ischemia symptoms suspected of having coronary heart disease (CHD) or coronary microvascular disease (CMVD), who are scheduled to undergo ECT examination.and a domestically manufactured \"ultra-high sensitivity\" cardiomagnetic detection device will be used to collect cardiac magnetic images. The ECT examination will be completed within one week. A consistency analysis will be conducted between the cardiac magnetic results and the ECT results to evaluate the early diagnostic efficacy of cardiac magnetic detection for myocardial ischemia. Subgroup analyses will also be performed based on resting and stress conditions.\n\nPrimary study endpoints:Diagnostic Performance of MCG in Detecting Myocardial Ischemia: Positive Predictive Value, Specificity, and Sensitivity.\n\nSecondary study endpoint:Concordance and Discrepancies Between MCG and ECT in Diagnosing Myocardial Ischemia.",[25],"Myocardial Ischemia",[27,28,25,29,30],"Coronary atherosclerotic Heart Disease","Coronary Microvascular Disease","Magnetocardiograph","Emission Computed Tomography","NOT_YET_RECRUITING","2025-07-13",{"date":34,"type":35},"2025-07-22","ACTUAL",{"date":37,"type":20},"2025-07",{"date":39,"type":20},"2026-07",{"name":41,"class":42},"Yang Jing","OTHER",""]