[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Yangzhou University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":137},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,68,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100638167","adapted-mindfulness-training-for-diabetic-patients-with-impaired-hypoglycemia-awareness-100638167",false,"NCT07586527","Adapted Mindfulness Training for Diabetic Patients With Impaired Hypoglycemia Awareness","Impact of Adapted Mindfulness Training Integrating Interoception on Diabetic Patients With Impaired Awareness of Hypoglycemia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosed with type 1 or type 2 diabetes mellitus according to the latest American Diabetes Association (ADA) Standards of Care in Diabetes;\n* Receiving insulin therapy for ≥ 1 year;\n* Age between 18 and 80 years (inclusive);\n* Duration of diabetes ≥ 5 years;\n* Gold score ≥ 4 and Clarke score ≥ 4;\n* Voluntary participation and provision of signed informed consent.\n\nExclusion Criteria:\n\n* Prior experience with mindfulness interventions;\n* Diagnosed with cognitive impairment, psychiatric disorders, or other severe physical comorbidities;\n* Current use of psychotropic medications;\n* Pregnant or lactating women, or women of childbearing potential not using effective contraception.","ALL","18 Years","80 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this randomized controlled trial is to evaluate the effectiveness of an 8-week interoception-integrated adapted mindfulness training program for patients with type 1 or type 2 diabetes who experience impaired awareness of hypoglycemia (IAH). The study aims to determine whether this mindfulness intervention, which includes techniques such as body scanning and mindful eating, can help patients better recognize early physiological signals of low blood sugar compared to routine care. Researchers will measure changes in participants' interoceptive awareness and the severity of their IAH over a 3-month follow-up period. The ultimate goal is to provide a practical psychological approach to improve symptom perception and reduce the risk of severe hypoglycemic events in diabetic patients.",[27,28,29],"Impaired Awareness of Hypoglycemia","Interoceptive Awareness","Mindfulness-based Intervention","NOT_YET_RECRUITING","2026-05-08",{"date":33,"type":34},"2026-05-14","ACTUAL",{"date":36,"type":21},"2026-06-01",{"date":38,"type":21},"2027-06-01",{"name":40,"class":41},"Yangzhou University","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":50,"minAge":17,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},"100555821","effect-of-teas-combined-with-oxycodone-on-postoperative-visceral-pain-in-gynecologic-laparoscopic-patients-100555821","NCT06517069","Effect of TEAS Combined With Oxycodone on Postoperative Visceral Pain in Gynecologic Laparoscopic Patients","Effect of Transcutaneous Electrical Acupoint Stimulation Combined With Oxycodone on Postoperative Visceral Pain and Early Recovery Quality in Gynecologic Laparoscopic Patients","Inclusion Criteria:\n\n* Age 18-65 years\n* American Society of Anesthesiologists grade I-II\n* Body mass index (BMI) 18.5-30 kg\u002Fm2;\n* No ulceration or infection at the acupuncture stimulation site.\n\nExclusion Criteria:\n\n* Allergic to the drugs used in the study;\n* People with unclear consciousness or cognitive dysfunction;\n* There are contraindications of percutaneous acupoint electrical stimulation;\n* Abnormal cardiopulmonary and liver and kidney function;\n* History of analgesic drug use within one week;\n* History of diabetes, myocardial infarction or cerebrovascular accident.",true,"FEMALE","65 Years",{"count":53,"type":21},120,[24],"To investigate the effect and feasibility of percutaneous acupoint stimulation combined with oxycodone on postoperative visceral pain in laparoscopic patients, and provided a clinical basis for optimizing perioperative pain management in laparoscopic patients.",[57],"Visceral Pain","RECRUITING","2024-07-27",{"date":61,"type":34},"2024-07-30",{"date":63,"type":34},"2024-05-01",{"date":65,"type":21},"2025-07-01",{"name":40,"class":41},1,{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":22,"phases":77,"briefSummary":78,"conditions":79,"keywords":85,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":67},"100551808","effects-of-a-health-intervention-on-fear-of-hypoglycemia-100551808","NCT06464900","Effects of a Health Intervention on Fear of Hypoglycemia","Effects of a Health Education Intervention Based on the Behaviour Change Wheel on Fear of Hypoglycemia in Patients With Type 2 Diabetes Mellitus: a Randomized Controlled Study","Inclusion Criteria:\n\n* Comply with the 2020 Chinese guidelines for the prevention and treatment of type 2 diabetes mellitus;\n* Age ≥18 years;\n* Duration of diabetes mellitus ≥1 year;\n* FoH according to the elevated item endorsement criterion (E I criterion): ≥3 points on any item of the Hypoglycemic Fear-Worry Scale (HFS-WS);\n* Patients who have the ability to listen, read, write, walk, and cooperate to complete the study;\n* Patients who have a smart phone, and can skillfully use WeChat or telephone to communicate;\n* Voluntarily participate in this study and sign the informed consent form.\n\nExclusion Criteria:\n\n* Patients with comorbid acute complications or other serious diseases or disorders of consciousness, such as diabetic hypertonic state, tumors, coma, etc;\n* Patients with comorbid psychiatric diseases or taking psychotropic drugs;\n* Patients who have recently or are participating in other studies on similar topics.",{"count":76,"type":21},90,[24],"To examine the effects of a health Education Intervention based on the Behaviour Change Wheel (BCW) theory on fear of hypoglycemia and relevant outcomes of type 2 diabetic patients.",[80,81,82,27,83,84],"Health-Related Behavior","Health Education","Fear of Hypoglycemia","Self-Management","Type2 Diabetes Mellitus",[86,87,88,89,90,91,92],"Behaviour Change Wheel","Health educational intervention","Fear of hypoglycaemic","Impaired awareness of hypoglycaemia","Medical support","Self-management attitude","Type 2 diabetes mellitus","2024-07-07",{"date":95,"type":34},"2024-07-09",{"date":97,"type":21},"2024-07",{"date":99,"type":21},"2025-01",{"name":40,"class":41},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":109,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":22,"phases":113,"briefSummary":114,"conditions":115,"keywords":118,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":67},"100507727","remimazolam-for-postoperative-atrial-fibrillation-100507727","NCT05891145","Remimazolam for Postoperative Atrial Fibrillation","The Effect of Remimazolam on Postoperative New-onset Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting","RePAF","Inclusion Criteria:\n\n* 50-70 years old;\n* BMI 18-28 kg\u002Fm2；\n* Selective CABG surgery will be performed at the Yangzhou Institute Heart and Great Vessels, the Affiliated Hospital of Yangzhou University, Yangzhou, China.\n* Patients agree to participate in this study and sign the informed consent form.\n\nExclusion Criteria:\n\n* Emergency surgery;\n* with any other type of cardiac surgery;\n* pre-operative supraventricular arrhythmia;\n* with moderate or severe valve disease before surgery;\n* with a history of chemotherapy or radiotherapy;\n* with a history of thoracic or cardiovascular surgery;\n* diuretics usage before the surgery.","50 Years","70 Years",{"count":112,"type":21},50,[24],"Atrial fibrillation (AF) is the most common cardiac severe arrhythmia globally and is associated with an increased risk of mortality and morbidity, with a loss of 6.0 million disability-adjusted life-years worldwide in 2017, conferring 0.24% of total disability-adjusted life-years globally. Due to the absence of knowledge of AF pathogenesis, currently, available therapies do not prevent AF onset or progression in 85% of patients. Despite the identification of novel druggable targets that are involved in the pathogenesis of AF, the translation of these findings to clinical drug studies is limited.\n\nPostoperative atrial fibrillation (POAF) is the most common type of secondary AF. The incidence of POAF after coronary artery bypass grafting (CABG) is approximately 30%. About 16% of patients developed POAF in cardiac surgery even with the international guideline recommended perioperative beta-blocker intervention.\n\nRemimazolam is a newly approved benzodiazepine sedative indicated for the induction and maintenance of procedural sedation in adults, with significantly reduced sedation and recovery time. It was also found to be with an anti-inflammatory effect and therefore might have an impact on POAF since AF is closely related to the inflammatory response of myocardial tissue and inflammatory factors such as TNF-α. So, the RePAF trial intends to explore whether remimazolam application in induction and maintenance for general anesthesia during cardiac surgery can reduce the incidence of POAF in patients with CABG, and the effect on the postoperative plasma levels of inflammatory factors and stress factors.",[116,117],"Coronary Artery Bypass Grafting","Remimazolam",[117,119,120,121,122,123,124,125,126,127,128],"CABG","Postoperative atrial fibrillation","Postoperative new-onset atrial fibrillation","Coronary artery disease","CAD","Coronary artery bypass graft","Myocardial infarction","Revascularization","Anesthesia","Ischemic heart disease","2023-06-05",{"date":131,"type":34},"2023-06-06",{"date":133,"type":34},"2023-02-01",{"date":135,"type":21},"2026-12",{"name":40,"class":41},""]