[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Zev Rymer\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100641234","spasticity-in-sci-following-acute-intermittent-hypoxia-100641234",false,"NCT07583498","Spasticity in SCI Following Acute Intermittent Hypoxia","Does the Administration of Acute Intermittent Hypoxia in Persons With Chronic Spinal Cord Injury Make Spasticity Worse?","Inclusion Criteria:\n\n* Age \\>= 18\n* Non-progressive spinal Cord injury at least 6 months prior\n* Level of injury between C1-C8\n* ISNCSCI ASIA classification C or D\n* Measurable Spasticity\n\nExclusion Criteria:\n\n* Pre-existing hypoxic pulmonary disease\n* Positive Covid-Pneumonia diagnosis within 1 year of visit\n* Uncontrolled hypertension \\>140\u002F90 mmHg\n* Individuals who are currently pregnant\u002Fnursing or planning on becoming pregnant\n* Individuals with a tracheostomy or who utilize mechanical ventilation\n* A botulinum toxin injection to upper extremity musculature within the past 3 months\n* Currently taking Baclofen\n* Congestive Heart Failure\n* Cardiac arrhythmias\n* Uncontrolled diabetes mellitus\n* Chronic obstructive pulmonary disease\n* Emphysema\n* Severe Asthma\n* Previous myocardial infarction\n* Carotid\u002Fintracerebral artery stenosis\n* Orthopedic injuries or surgeries that impact the ability to use the upper extremity\n* History of Epilepsy","ALL","18 Years",{"count":19,"type":20},10,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to observe the effects of administration of a breathing intervention (Acute Intermittent Hypoxia (AIH)) on spasticity (tightness) in individuals with incomplete Spinal Cord Injury. It is hypothesized that hypoxia will decrease the reflex threshold of the biceps brachii, indicating an increase in spasticity following the AIH.",[26],"Spinal Cord Injuries (SCI)",[28,29,30],"Hypoxia","Spasticity","Reflex","RECRUITING","2026-05-07",{"date":34,"type":35},"2026-05-13","ACTUAL",{"date":37,"type":35},"2026-03-17",{"date":39,"type":20},"2028-03",{"name":41,"class":42},"Zev Rymer","OTHER",""]