[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Zhifen Liu\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100572055","efficacy-and-safety-of-dtms-in-adolescent-major-depressive-disorder-100572055",false,"NCT06728280","Efficacy and Safety of DTMS in Adolescent Major Depressive Disorder","Efficacy and Safety of Deep Transcranial Magnetic Stimulation in Adolescent Major Depressive Disorder: a Prospective Double-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients of all genders, aged between 11 and 23 years old, and right-handedness.\n* In accordance with the diagnostic criteria for the major depressive disorder of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5).\n* The current major depressive episode (MDE) must be confirmed using the Mini International Neuropsychiatric Interview (M.I.N.I).\n* Beck Depression Inventory, Second Edition (BDI-II): total BDI-II score\\> 13 at screening.\n* Subjects who can understand and are willing to strictly follow the clinical trial protocol to complete this study and sign informed consent.\n\nExclusion Criteria:\n\n* A diagnosis of other psychiatric disorders in the DSM-5.\n* Clinically significant laboratory abnormality or medical condition, that in the opinion of the investigator would hinder the subject in completing the procedures required by the study.\n* History of significant neurologic disease, including subdural hematoma, brain tumor, unexpected seizure\u002Fepilepsy disorder, or history of significant head trauma.\n* Have obvious suicide risk, or have actual suicide behavior within 6 months before the screening.\n* History of treatment with electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), transcranial Direct Current Stimulation (tDCS), or transcranial Alternating Current Stimulation (tACS) treatments for any disorders.\n* There are contraindications to magnetic resonance imaging (MRI) scanning or TMS treatment, such as metal or electronic instruments.\n* Participation in any investigational drug trial within 6 months before the baseline visit.\n* Other conditions that are not suitable for the study object in the researcher's judgment.","ALL","11 Years","23 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this randomized controlled trial is to explore the efficacy and safety of two different dTMS devices in adolescent depression: deep TMS H1 coil and deep TMS H7 coil.\n\nThe main questions it aims to answer are:\n\nType of study: Clinical trial. Participant population: Adolescents with major depressive disorder (MDD). Objective: To explore whether the H7 coil is no less effective than the H1 coil for adolescents with MDD, further providing clinicians with additional treatment options for patients.",[27],"Major Depressive Diorder",[29,27,30],"deep transcranial magnetic stimulation","adolescents","RECRUITING","2025-03-10",{"date":34,"type":35},"2025-03-12","ACTUAL",{"date":37,"type":35},"2024-12-31",{"date":39,"type":21},"2026-06-30",{"name":41,"class":42},"Zhifen Liu","OTHER",2,""]