[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Zhonghui K. Luo, MD, PhD\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100605771","electrostimulation-study-for-ocular-graft-vs-host-disease-100605771",false,"NCT07166848","Electrostimulation Study for Ocular Graft vs. Host Disease","Pilot Trial of Non-invasive Electrostimulation in Chronic Ocular Graft-vs-Host Disease","Inclusion Criteria:\n\n* Diagnosis of chronic ocular graft vs. host disease (oGVHD) (ICCGVHD criteria probable or definite)\n* OSDI score of 22 or higher\n* NEI corneal staining score (or modified NEI score) of 2 or higher.\n\nExclusion Criteria:\n\n* Patients with any open wound on the eyelid.\n* Patient with any active cornea ulcer, dacryocystitis, hordeolum, filamentary keratitis, uveitis, retinal detachment, uncontrolled glaucoma or other active pathology per PI's discretion.\n* Patient with a pacemaker or ICD.\n* Patient currently pregnant or with a potential to be pregnant during the study.\n* Patient undergoing any ocular surgical procedure (including intravitreal injections) within the past 3 months.\n* Patient undergoing any systemic surgical procedures within 2 months.\n* Patient undergoing any non-surgical eyelid procedure such as punctal plugs or punctal cautery within 1 month of study initiation.\n* Patients on cytotoxic agents, drugs that inhibit peripheral nerve regeneration (i.e. Gabapentin, Nicotine), radiation therapy, or any other therapy per PI's discretion.\n* Patients undergoing immunosuppression regimen change within 1 month of study initiation and\u002For during the study period.\n* Patient who wears contact lens of any kind","ALL","18 Years","75 Years",{"count":20,"type":21},15,"ESTIMATED","INTERVENTIONAL",[24],"NA","This trial is testing to see if electrostimulation treatment (ET) will be effective in treating those with ocular Graft vs. Host Disease.",[27],"Chronic Ocular Graft-versus-host Disease",[29,30],"GVHD","Electrostimulation","RECRUITING","2025-12-09",{"date":34,"type":35},"2025-12-17","ACTUAL",{"date":37,"type":35},"2025-11-30",{"date":39,"type":21},"2029-11-30",{"name":41,"class":42},"Zhonghui K. Luo, MD, PhD","OTHER",""]