[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"dr Pim A.L. Tonino\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100621134","savvywire-for-pacing-and-procedural-hemodynamics-in-transcatheter-aortic-valve-replacement-evaluation-100621134",false,"NCT07366671","SAvvywire for Pacing and Procedural Hemodynamics In Transcatheter Aortic Valve Replacement Evaluation","SAvvywire for Pacing and Procedural Hemodynamics In Transcatheter Aortic Valve Replacement Evaluation; a Prospective Registry (SAPPHIRE)","SAPPHIRE","Inclusion Criteria:\n\n* Age ≥ 50 years\n* Accepted for transfemoral TAVI procedure by Heart team and TAVI team\n* Transfemoral TAVI procedure with balloon-expandable or self-expandable TAVI platform\n* Ability to understand and the willingness to provide written informed consent\n* Patients scheduled for valve-in-valve procedures can be included\n* Patients with bicuspid anatomy can be included\n\nExclusion Criteria:\n\n* Patients planned for a non-transfemoral TAVI procedure\n* Extremely horizontal aorta (aortic root angle \\>70 degrees)\n* Extreme tortuosity at the level of the iliofemoral arteries, abdominal and\u002For thoracic aorta\n* Inability to provide informed consent.","ALL","50 Years",{"count":20,"type":21},300,"ESTIMATED","3 Months","OBSERVATIONAL","The goal of this observational study is to document which LV-guidewires are used during a TAVI (Transcatheter Aortic Valve Implantation) procedure and how their different functions perform.\n\nA TAVI procedure is a minimally invasive treatment for aortic stenosis, where a new heart valve is inserted through a blood vessel in the groin. During this procedure, a wire (specifically, an LV-guidewire) is used to place the new heart valve. For this purpose, a regular LV-guidewire or a newer LV-guidewire with extra features, the Savvywire, can be used. All of these wires work well, are safe, and are already used in daily medical practice. Researchers will compare these LV-guidewires to see if the Savvywire adds additional value.\n\nPatients aged 50 or older who undergo a TAVI procedure via the femoral artery (blood vessel in the groin) can participate. Participants will receive the usual care and standard follow-up, only their data will be collected and analyzed.",[26,27],"TAVI(Transcatheter Aortic Valve Implantation)","Aortic Valve Disease","RECRUITING","2026-03-10",{"date":31,"type":32},"2026-03-11","ACTUAL",{"date":34,"type":32},"2026-01-12",{"date":36,"type":21},"2028-03",{"name":38,"class":39},"dr Pim A.L. Tonino","OTHER",""]