[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"prof. dr. Rik Schrijvers\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":71},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100613077","ex-vivo-evaluation-of-jak-inhibitor-and-gene-therapeutical-approach-in-jak-stat-related-disorders-100613077",false,"NCT07261891","Ex Vivo Evaluation of JAK-inhibitor and Gene Therapeutical Approach in JAK-STAT Related Disorders","Ex Vivo Evaluation of JAK-inhibitor and Gene Therapeutical Approach in JAK-STAT Related Disorders (JAKarta Study)","JAKarta","Inclusion Criteria:\n\n* Cases (A): adult patients presenting with a genetically confirmed or highly suspected disorder leading to an exagerated JAK-STAT pathway.\n* Controls (B): participants eligible for inclusion in this study must fall in one of the following categories:\n* Healthy controls (without immune-mediated disease)\n\nExclusion Criteria:\n\n* Children (\\\u003C 18 years at time of recruitment)\n* Persons unable or unwilling to give informed consent",true,"ALL","18 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"NA","The investigators want to study the JAK-inhibitors and their impact on the immune system and evaluate the potential of a gene-therapeutic strategy",[28],"Primary Immunodeficiency Diseases (PID)",[30,31,32],"JAK inhibitors","STAT1 gain-of-function","gene therapy","RECRUITING","2025-11-28",{"date":36,"type":37},"2025-12-03","ACTUAL",{"date":39,"type":37},"2024-11-21",{"date":41,"type":22},"2030-12-01",{"name":43,"class":44},"prof. dr. Rik Schrijvers","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":45},"100570969","impacts-of-nitrogen-deposition-in-the-natural-environment-on-pollen-allergy-in-belgium-100570969","NCT06714149","Impacts of Nitrogen Deposition in the Natural Environment on Pollen Allergy in Belgium","NITROPOL-BE","Inclusion Criteria:\n\n* Positive skin prick test for grass and\u002For birch pollen\n\nExclusion Criteria:\n\n* Desensitization therapy during the last two years",{"count":54,"type":22},200,[25],"The investigators want to study the effect of environmental nitrogen enrichment on the allergy burden in pollen-sensitized subjects.",[58],"Pollen Allergy",[60,61,62],"Nitrogen","Pollution","Pollen allergy","2024-12-02",{"date":65,"type":37},"2024-12-03",{"date":67,"type":37},"2022-06-29",{"date":69,"type":22},"2025-04",{"name":43,"class":44},""]