[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"abdominal-pain-ap\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:abdominal-pain-ap":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,46,71,109,140,171,201,242],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100643267","empowered-relief-for-caregivers-100643267",false,"NCT07636980","Empowered Relief for Caregivers","Empowered Relief for Caregivers (ER-CY): A Co-Designed Brief Intervention to Support Families of Youth With Chronic Pain","ER-CY","Inclusion Criteria:\n\n* Caregiver of a youth with a chronic pain diagnosis (\\>3 months in duration)\n* English speaking\n\nExclusion Criteria:\n\n* Significant psychosocial complexity based on clinical team assessment (e.g., severe depression\u002Fanxiety, unable to tolerate a group setting)","ALL","18 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study is testing a new program called Empowered Relief for Caregivers (ER-CY), designed to support caregivers of children and teens who live with chronic pain. ER-CY is a single two-hour class delivered online. It teaches skills for managing the stress of caring for a child in pain and for responding to a child's pain in helpful ways.\n\nUp to 80 caregivers of youth with chronic pain will take part in one ER-CY class and then complete surveys and a short interview over the following three months. The researchers want to learn two things: whether caregivers are willing and able to take part and find the program helpful and satisfying, and whether the program lowers caregiver distress and improves their child's day-to-day functioning. What is learned will help guide future programs and care for youth with chronic pain and their families.",[27,28,29,30,31,32],"Chronic Pain","Musculoskeletal Pain","Fibromyalgia","Neuropathic Pain","Complex Regional Pain Syndromes (CRPS)","Abdominal Pain (AP)","NOT_YET_RECRUITING","2026-06-03",{"date":36,"type":37},"2026-06-09","ACTUAL",{"date":39,"type":21},"2026-10",{"date":41,"type":21},"2028-09",{"name":43,"class":44},"Stanford University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":45},"100565856","a-pilot-study-to-assess-the-safety-tolerability-and-efficacy-of-virtual-reality-for-the-treatment-of-abdominal-pain-in-quiescent-crohns-disease-100565856","NCT06647615","A Pilot Study to Assess the Safety, Tolerability, and Efficacy of Virtual Reality for the Treatment of Abdominal Pain in Quiescent Crohn's Disease","Inclusion Criteria:\n\n* Patients with a diagnosis of endoscopically and histologically confirmed CD with evidence of C-reactive protein \\< 5 mg\u002FdL and fecal calprotectin \\< 150microg\u002Fg who also report any abdominal pain at least weekly will be included.\n\nExclusion Criteria:\n\n* Patients will be excluded from the study if they do not have biopsy-proven CD, have a known seizure disorder, if symptoms are thought to represent an organic disorder, those with visual or hearing impairments, if symptoms represent a known pelvic floor disorder, if the patient is using opioids, has significant ongoing psychological distress (HAD score \\> 11 for either anxiety or depression), or if the patient can not actively participate in the study for any other reason (e.g., inability to understand English as the VR program as an English only).","70 Years",{"count":54,"type":21},15,[24],"The purpose of this research is to see if patients with Crohn's disease (CD) and abdominal pain resulting in health-related quality of life deficits despite lack of evidence of active inflammation improve with the use of virtual reality (VR).",[58,32],"Crohn's Disease",[58,60],"Quiescent Crohn's Disease","RECRUITING","2026-02-12",{"date":64,"type":37},"2026-02-17",{"date":66,"type":37},"2024-05-24",{"date":68,"type":21},"2026-12-31",{"name":70,"class":44},"Mayo Clinic",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":82,"conditions":83,"keywords":96,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":45},"100624078","the-effect-of-surgical-mask-and-n95-mask-use-on-surgical-smoke-in-operating-room-nurses-100624078","NCT07404956","THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES","COMPARISON OF THE EFFECTS OF SURGICAL MASK AND N95 MASK USE ON PHYSICAL SYMPTOMS OF SURGICAL SMOKE IN OPERATING ROOM","Inclusion Criteria:\n\n* Willingness to participate in the study\n* Aged 18 years or older\n* Working as a sterile operating room nurse at least 4 hours per day, 5 days per week\n* Compliance with the protocol requiring continuous use of both surgical mask and N95 mask for at least 4 hours per day\n* Ability to communicate verbally and provide informed consent\n\nExclusion Criteria:\n\n* Diagnosed psychiatric disorders\n* Presence of chronic respiratory, musculoskeletal, or neurological diseases\n* Presence of chronic dermatological conditions or allergies affecting the facial or respiratory area\n* Speech or communication impairments\n* Pregnancy\n* Holding a supervisory role (e.g., charge nurse) or non-sterile nursing role\n* Planned unit change or rotation during the study period",true,{"count":80,"type":21},38,[24],"This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses. The study, which was conducted in a single-group prospective quasi-experimental design, was completed with 38 nurses in the operating theatre unit of a state hospital in the Western Black Sea Region. Data were collected for four weeks using the Descriptive Information Form, Numerical Rating Scale and Symptom Follow-up Form. According to the findings, muscle weakness, myalgia in the upper extremities and muscle cramps were statistically significantly less in nurses using N95 masks. Respiratory parameters, watery eyes and redness were significantly lower in nurses using surgical masks. As a result, it was determined that the type of mask was effective on the incidence of physical symptoms related to surgical smoke.",[84,85,86,87,88,89,90,32,91,92,93,94,95],"Surgical Smoke Exposure","Occupational Exposure to Surgical Smoke","Headache","Dizziness","Nause and Vomiting","Fatigue Symptom","Eye Allergies","Heart Rate Determination","SpO2","Muscle Weakness | Patient","Muscle Aches","Dispnea",[97,98,99,100],"Surgical Smoke","Masks","Operating Room Nurses","Occupational Exposure","2026-02-09",{"date":62,"type":37},{"date":104,"type":37},"2024-09-15",{"date":106,"type":21},"2026-02-28",{"name":108,"class":44},"Bartın Unıversity",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":117,"targetDuration":119,"studyType":120,"phases":4,"briefSummary":121,"conditions":122,"keywords":128,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":45},"100432993","functional-digestive-disorders-observatory-100432993","NCT04918329","Functional Digestive Disorders Observatory","Observatory of Functionnal Digestive Disorders","OTFI","Inclusion Criteria:\n\n* Patients over 18 years of age;\n* Patients with functional digestive disorder for more of 3 months;\n* Patients assessed as part of routine care;\n* Patients affiliated to the Social Security ;\n* Patients not opposed to participation in the Centre\n\nExclusion Criteria:\n\n* Person deprived of liberty by administrative or judicial decision or major protected subject (under guardianship or curatorship);\n* Patients unable for any reason to read, understand, respond questionnaires (visual, psychiatric, cognitive, etc.)",{"count":118,"type":21},2000,"10 Years","OBSERVATIONAL","Functional digestive pathologies are defined by symptoms such as functional dyspepsia, gastroesophageal reflux, irritable bowel syndrome, gastroesophageal reflux, functional constipation, functional diarrhea, functional bloating, the opioid-induced constipation and fecal incontinence, without organic substratum. These diseases are very common in the general population (20%) and represent the first cause of consultation in city gastroenterology. The pathophysiology of these functional disorders is complex and often multifactorial: disturbances in digestive motility, altered visceral sensitivity, sphincter dysfunction, post-surgery, intestinal inflammation, dysbiosis, and impairment of the gut-brain axis. For example, it has been shown that one in four patients with inflammatory bowel disease in confirmed remission report digestive symptoms consistent with a functional bowel disorder, suggesting a possible pathophysiological continuum between these two conditions.\n\nThe objective of this study is to collect prospective clinical and tests data and a biological collection from biological samples (digestive biopsies, blood, urine and fecal samples) collected as part of the standard care. This collection could identify diagnostic or prognostic markers of the therapeutic response.",[123,124,125,126,32,127],"Irritable Bowel Syndrome","Dyspepsia","Functional Constipation","Faecal Incontinence","Vomiting Syndrome",[129,130],"Observatory","functional digestive disorders","2026-01-05",{"date":133,"type":37},"2026-01-08",{"date":135,"type":37},"2020-10-09",{"date":137,"type":21},"2030-10-09",{"name":139,"class":44},"University Hospital, Rouen",{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":144,"acronym":4,"eligibilityCriteria":145,"healthyVolunteers":78,"sex":17,"minAge":146,"maxAge":147,"enrollmentInfo":148,"targetDuration":4,"studyType":120,"phases":4,"briefSummary":150,"conditions":151,"keywords":157,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":4},"100618878","co-development-and-validation-of-colonic-symptom-pictograms-for-young-people-100618878","NCT07337343","Co-Development and Validation of Colonic Symptom Pictograms for Young People","Inclusion Criteria:\n\nChildren and Young people are aged between 8-17 years,\n\n* have lower gut or constipation symptoms,\n* can communicate in English or be supported to participate by a caregiver, whānau, or other responsible person. Phase Four will include international invitations to participants with lower gut or constipation symptoms. Healthy volunteers will not be recruited.\n\nExclusion Criteria:\n\n* Children and Young people with developmental or cognitive disorder that precludes their ability to understand the study,\n* Children and Young people who do not have access to a digital device with internet connectivity,\n* unable to read English,\n* parent does not consent","8 Years","17 Years",{"count":149,"type":21},120,"Severe constipation affects 10% of children, often leading to significant physical and emotional distress. While constipation is commonly associated with impaired bowel movements, it is fundamentally linked to abnormalities in colonic motility - the coordinated contractions that facilitate passage of stool through the colon and out of the body. Diagnosis of constipation is based upon the Rome IV criteria, which assess symptoms as reported or remembered over the previous 3 months.\n\nHowever, reporting symptoms experienced can be challenging for children and young people for many reasons, such as the overlap of sensations, including fullness, bloating, and discomfort, and an inability to recall or precisely distinguish and describe what they are feeling.\n\nThis study intends to design, develop, and validate symptom pictograms for children aged 8-17 with colonic or lower gut symptoms.",[152,32,153,154,155,156],"Constipation - Functional","Nausea and Vomitting","Bloating","Flatulence","IBS, Constipation Predominant",[158,159,160,161],"children and adolescents","pictograms","co-design","validation","2026-01-02",{"date":164,"type":37},"2026-01-13",{"date":166,"type":21},"2026-01-01",{"date":168,"type":21},"2027-04-01",{"name":170,"class":44},"University of Auckland, New Zealand",{"id":172,"slug":173,"hasResults":11,"nctId":174,"briefTitle":175,"officialTitle":175,"acronym":176,"eligibilityCriteria":177,"healthyVolunteers":78,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":178,"targetDuration":4,"studyType":22,"phases":180,"briefSummary":181,"conditions":182,"keywords":184,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":4},"100615980","outcome-of-active-aspiration-versus-simple-compression-to-remove-residual-gas-from-abdominal-cavity-in-reducing-pain-after-laparoscopic-cholecystectomy-100615980","NCT07299656","Outcome of Active Aspiration Versus Simple Compression to Remove Residual Gas From Abdominal Cavity in Reducing Pain After Laparoscopic Cholecystectomy","Lap Chole","Inclusion criteria:\n\n* Patients of both genders.\n* Patients of age ≥ 18 years.\n* All patients presenting for elective laparoscopic cholecystectomy.\n\nExclusion Criteria:\n\n* Patients suffering from obstructive jaundice anamnesis.\n* Patients who had received a diagnosis of gallbladder cancer.\n* Patients whose procedures were converted to open cholecystectomy during the surgery.\n* Patients who had additional pathologies such as bronchial asthma, chronic obstructive pulmonary disease.\n* Patients refused to give consent.",{"count":179,"type":21},62,[24],"The aim of this study is to compare outcome of active aspiration versus simple compression to remove residual gas from abdominal cavity in reducing pain after laparoscopic cholecystectomy.",[183,32],"Shoulder Pain",[185,186,187,188,189,190,191],"abdominal pain","shoulder pain","laparoscopic procedure","cholecystectomy","pneumoperitonium","lap chole","laparoscopic cholecystectomy","2025-12-10",{"date":194,"type":37},"2025-12-23",{"date":196,"type":21},"2025-12-11",{"date":198,"type":21},"2027-01-30",{"name":200,"class":44},"King Edward Medical University",{"id":202,"slug":203,"hasResults":11,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":207,"eligibilityCriteria":208,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":209,"targetDuration":4,"studyType":22,"phases":211,"briefSummary":212,"conditions":213,"keywords":223,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":239,"locationsCount":45},"100566450","efficiency-of-the-medidux-smartphone-app-for-demission-management-in-patients-medicated-in-acute-admission-unit-aau-100566450","NCT06655337","Efficiency of the \"Medidux\" Smartphone App for Demission Management in Patients Medicated in Acute Admission Unit (AAU)","Efficiency of the \"Medidux\" Smartphone App for Demission Management in Patients Medicated in Acute Admission Unit (AAU): a Randomized Controlled Trial.","EffiDux","Inclusion Criteria:\n\n* Signed Informed Consent Form (ICF)\n* Age ≥ 18 years\n* (Self-)admission to the involved Acute Admissions Unit (AAU)\n* \"Lead symptom\" identified as coughing, back pain or abdominal discomfort\n* Participant within ESI triage system group 4 (standard) and 5 (non-urgent)\n* German-speaking\n* Ownership of a smartphone or other mobile device with iOS or Android operating system\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Participant whose compliance to the study's protocol, e.g. due to mental health problems, physical problems, or the private life situation, can be justifiably doubted\n* Participant with insufficient knowledge about the use of a smartphone or other mobile device with iOS or Android operating system\n* Participant already using or planning to use another comparable electronic patient-reported symptom monitoring system (e.g. CANKADO) during this trial",{"count":210,"type":21},417,[24],"The goal of this clinical trial is to evaluate whether the use of the medidux™ smartphone app can optimize post-discharge management for patients admitted to Acute Admission Units (AAU) with non-urgent health complaints. This trial includes adult patients (age ≥ 18) in Emergency Severity Index (ESI) triage system groups 4 (standard) or 5 (non-urgent), presenting with primary symptoms such as cough, back pain, or abdominal discomfort.\n\nThe main question it aims to answer is:\n\nCan the medidux™ app reduce the incidence of AAU readmissions, emergency hospitalizations, or consultations with other medical providers within 7 days after initial admission?\n\nResearchers will compare participants using the medidux™ app (intervention arm) with those receiving standard care (control arm) to observe potential differences in the rates of readmissions, emergency hospitalizations, and medical consultations.\n\nParticipants will:\n\n* use the medidux™ app to monitor their symptoms and vital parameters for 7 days after discharge (intervention arm).\n* receive follow-up consultations at day 7 and at day 28 to assess symptom progression and any healthcare interactions (both arms).",[214,215,216,217,32,218,219,220,221,222],"Acute Disease","Acute Hospitalization","Coughing","Back Pain","Patient Discharge","Patient Readmission","Mobile Health Apps","Mobile Health Technology (mHealth)","Patient Reported Outcome (PRO)",[214,218,219,216,217,224,225,226,227,228,229,230,231],"Abdominal Pain","Mobile Health Applications","Remote Monitoring","Post-discharge Care","Symptom Monitoring","Health Behaviour","Telemedicine","Randomized Controlled Trial","2025-09-29",{"date":234,"type":37},"2025-10-03",{"date":236,"type":37},"2025-09-28",{"date":238,"type":21},"2027-03-28",{"name":240,"class":241},"Mobile Health AG","INDUSTRY",{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":246,"acronym":4,"eligibilityCriteria":247,"healthyVolunteers":78,"sex":17,"minAge":248,"maxAge":147,"enrollmentInfo":249,"targetDuration":4,"studyType":120,"phases":4,"briefSummary":251,"conditions":252,"keywords":255,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":260,"startDateStruct":262,"completionDateStruct":264,"leadSponsor":266,"locationsCount":45},"100593565","prostaglandin-e-urinary-metabolite-pge-m-as-a-predictor-of-acute-appendicitis-in-children-100593565","NCT07008092","Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in Children","Inclusion Criteria:\n\n* children of age 5 -17 years with acute abdominal pain\n* children with clinical signs of acute appendicitis\n\nExclusion Criteria:\n\n* previous diagnosis of chronic and\u002For malignant disease\n* children who had previous abdominal surgery\n* pregnancy","5 Years",{"count":250,"type":21},100,"Diagnosing acute appendicitis in children remains a clinical challenge, with delayed or incorrect diagnosis potentially leading to serious complications or unnecessary surgery. Prostaglandin E urinary metabolites (PGE-M) have been found elevated in various inflammatory conditions, but their diagnostic value in pediatric appendicitis is not well established. This study aims to assess the potential of PGE-M as a biomarker for acute appendicitis in children.\n\nThe study will be conducted over 12 months and will include 100 children aged 5 to 17 years presenting with acute abdominal pain. In addition to routine laboratory tests, urinary PGE-M levels will be analyzed. The study involves minimal risk to participants",[253,254,32],"Acute Appendicitis","Acute Appendicitis With Rupture",[256,257,258],"Acute appendicitis","PGE-M","Prostaglandin-E urinary metabolite","2025-05-29",{"date":261,"type":37},"2025-06-06",{"date":263,"type":21},"2025-06-02",{"date":265,"type":21},"2026-05-01",{"name":267,"class":44},"KBC Split"]