[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acceptability-of-health-care\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acceptability-of-health-care":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,53,82,121,145,178,216],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100543973","evaluation-of-reacts-in-an-intervention-to-improve-nutrition-hygiene-and-sexual-and-reproductive-health-services-100543973",false,"NCT06362837","Evaluation of REACTS-IN, an Intervention to Improve Nutrition, Hygiene, and Sexual and Reproductive Health Services","Realizing Gender Equality, Attitudinal Change & Transformative Systems in Nutrition (REACTS-IN)","REACTS-IN","Inclusion Criteria:\n\n(i)Women:\n\n* 15-49 y of age\n* biological mother of child in the home who is 0-5.9, 6-23.9, or 24-59.9 months\n* has lived in the community for at 12 months\n\n(ii) Husbands\u002Fpartners:\n\n* no age limit\n* lives in the home with index woman\n* has lived in community for at least 12 months\n\n(iii) Adolescents:\n\n* 10-19 years\n* male or female\n* has been in target school for at least 6 months\n* lives in the target community\n\n(iv) Children:\n\n* 0-5.9, 6-23.9, or 24-59.9 months\n\nExclusion Criteria:\n\n(i) Children:\n\n* no limitation on normal diet or growth (birth defects, illnesses)","ALL",{"count":19,"type":20},13500,"ESTIMATED","INTERVENTIONAL",[23],"NA","This is an independent evaluation of World VIsion's 7-year quasi-experimental intervention to improve nutrition, nutrition-related rights and gender equality for women, adolescent girls, and children under five years of age in rural Bangladesh, Kenya, and Tanzania. The evaluation will collect baseline, midline, and end-line data from intervention communities, schools, and health facilities. Only baseline and endline will be collected on the comparison communities. The evaluation objectives are to test if the intervention improved indicators for (i) child anthropometry, (ii) maternal and child dietary practices, (iii) women's empowerment, and (iv) equitable health service access for nutrition and sexual and reproductive needs. The evaluation analysis will take into account gender differences in the indicators.",[26,27,28,29,30],"Stunting","Gender Equality","Acceptability of Health Care","Diet; Deficiency","Empowerment",[32,33,34,35,36,37,38,39],"nutrition","gender equity","health services","sexual and reproductive rights","dietary diversity","anthropometry","sexual and reproductive health services","WASH","RECRUITING","2026-04-27",{"date":43,"type":44},"2026-04-29","ACTUAL",{"date":46,"type":44},"2024-09-01",{"date":48,"type":20},"2029-12-31",{"name":50,"class":51},"McGill University","OTHER",3,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":17,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":21,"phases":64,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":81},"100585101","feasibility-of-a-nutrition-intervention-for-patients-with-prediabetes-at-a-federally-qualified-health-center-100585101","NCT06897982","Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center","One-arm Feasibility and Acceptability Pilot Study of a Community-informed Nutrition Intervention to Recruit, Engage, and Retain Patients Who Are Eligible to Participate in the Diabetes Prevention Program at Two Community Health Centers in Los Angeles","Inclusion Criteria:\n\n* 18+ years old\n* BMI of 25 or higher (23 or higher if Asian)\n* Meet specific blood sugar test criteria indicating prediabetes, such as a fasting plasma glucose level between 110-125 mg\u002FdL or an A1C level between 5.7-6.4%\n* Not be diagnosed with type 1 or type 2 diabetes\n* Moderate to high risk of having prediabetes or a known diagnosis of prediabetes by their medical provider in the last 12 months.\n* Eligible or enrolled in the Diabetes Prevention Program\n\nExclusion Criteria:\n\n* Younger than 18 years of age\n* BMI of less than 25 or higher (or under 23 if Asian)\n* Does not meet specific blood sugar test criteria indicating prediabetes, such as a fasting plasma glucose level between 110-125 mg\u002FdL or an A1C level between 5.7-6.4%\n* Currently diagnosed with type 1 or type 2 diabetes\n* Has not been diagnosed as moderate to high risk of having prediabetes or having a known diagnosis of prediabetes by their medical provider in the last 12 months.","18 Years","99 Years",{"count":63,"type":20},20,[23],"The purpose of the study is to assess the feasibility and acceptability of incorporating hands-on nutritional demonstrations to enhance the Diabetes Prevention Program (DPP) curriculum among patients who are at-risk for prediabetes",[67,68,69,70,28,71],"Prediabetic State","PreDiabetes","Health Knowledge, Attitudes, Practice","Nutrition, Healthy","Obesity Prevention","2026-01-15",{"date":74,"type":44},"2026-01-20",{"date":76,"type":44},"2025-12-08",{"date":78,"type":20},"2027-02-28",{"name":80,"class":51},"Cedars-Sinai Medical Center",1,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":60,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":21,"phases":91,"briefSummary":92,"conditions":93,"keywords":94,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":52},"100552828","closed-blood-sampling-devices-in-the-adult-critically-ill-patient-100552828","NCT06478160","Closed-blood Sampling Devices in the Adult Critically Ill Patient","Effectiveness of Closed-blood Sampling Devices in the Adult Critically Ill Patient: Multicenter Randomized Clinical Trial","Inclusion Criteria:\n\n* Adult patients with an arterial catheter who agree to participate in the study, with a stay in the ICU of 24h and a minimum of 72h more with an arterial catheter\n\nNon-inclusion criteria: Therapeutic Limitation of Life Support, Jehovah's Witnesses.\n\nExclusion Criteria:\n\n* Patients with chronic renal failure\n* Patients with active gastrointestinal bleeding\n* Patients diagnosed with hematologic cancer\n* Women with menstruation at the time of admission\n* Pregnant women\n\nWithdrawal criteria: presence of active gastrointestinal bleeding during the study inclusion period.",{"count":90,"type":20},216,[23],"Based on the hypothesis that the strategy of using Closed-Blood Sampling Devices (CSBD, experimental group) compared to the usual practice (waste discard volume, control group), in critically ill adult patients, will decrease the amount of blood withdrawn for laboratory tests, we want to analyze the number of red blood cells (RBC) administered and arterial catheter-related adverse events (catheter-related bacteremia, catheter obstruction, CBSD malfunction, loss of arterial pressure waveform on the patient's bedside monitor) in both study groups, during ICU stay and up to a maximum of 21 days.",[28],[95,96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111],"anaemia","transfusion","diagnostic blood loss","phlebotomy","blood management","hospital-acquired anemia","iatrogenic anemia","sampling practices","blood conservation","blood sample collection","catheter-related infections","critical care","nursing","blood conservation devices","clinical trial","laboratory testing","blood chemistry tests","2025-11-06",{"date":114,"type":44},"2025-11-10",{"date":116,"type":44},"2024-11-11",{"date":118,"type":20},"2026-06-07",{"name":120,"class":51},"University of Barcelona",{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":4,"eligibilityCriteria":127,"healthyVolunteers":128,"sex":17,"minAge":60,"maxAge":4,"enrollmentInfo":129,"targetDuration":4,"studyType":21,"phases":131,"briefSummary":132,"conditions":133,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":81},"100456481","re-connect-application-for-smoking-cessation-100456481","NCT05224154","Re-Connect Application for Smoking Cessation","Re-Connect Usability, Feasibility, Acceptability, and Preliminary Efficacy Testing","Inclusion Criteria:\n\n* individuals who report smoking at least 10 cigarettes per day for at least 2 years, -18 years of age or older\n* do not have any health complications that might interfere with the study or require more intensive treatment (e.g., emphysema, chronic obstructive pulmonary disorder, asthma, lactose intolerance)\n* report a strong desire to quit smoking (8 or higher on a 10-point Likert scale)\n* has prior experience using a smartphone, speak English, and are literate, will be eligible for the study.\n\nExclusion Criteria:\n\n* Individuals with mental health complications that are either un-managed or that have been managed for less than 6-months",true,{"count":130,"type":20},82,[23],"This series of studies will explore the acceptability, feasibility, and preliminary efficacy of making access to smartphone applications contingent on objective evidence of smoking abstinence.",[134,28,135],"Smoking Cessation","Nicotine Dependence, Cigarettes","2025-02-26",{"date":138,"type":44},"2025-02-28",{"date":140,"type":44},"2021-12-14",{"date":142,"type":20},"2026-03-31",{"name":144,"class":51},"Rowan University",{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":151,"eligibilityCriteria":152,"healthyVolunteers":11,"sex":17,"minAge":60,"maxAge":4,"enrollmentInfo":153,"targetDuration":4,"studyType":155,"phases":4,"briefSummary":156,"conditions":157,"keywords":161,"overallStatus":168,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":81},"100503467","switch-from-oral-therapy-to-long-acting-injectable-cabotegravir--rilpivirine-100503467","NCT05835635","Switch From Oral Therapy to Long-acting Injectable Cabotegravir + Rilpivirine","Level of Satisfaction and Quality of Life in People Living With HIV in Chile, Who Switch From Oral Therapy to Long-acting Injectable Cabotegravir + Rilpivirine","CABO-LA","Inclusion Criteria:\n\nAll patients who, according to the recommendations for use, can receive LA- injectable Cabotegravir +Rilpivirine therapy will be invited to participate in the study.\n\nRecommendations for use:\n\n* HIV-1 positive patients, on antiretroviral therapy\n* Older than 18 years of age at the time of signing the informed consent\n* Undetectable HIV viral load in the last 6 months\n* Willing to switch from oral to injectable therapy\n\nExclusion Criteria:\n\nThese criteria are defined for those patients who, according to the recommendations for use, cannot receive the therapy:\n\n* Previous virological failure\n* Any evidence of primary resistance or the presence of any major known INI or NNRTI resistance-associated mutation by any historical resistance test result.\n* Patients with decompensated pathology (physical or mental) or active opportunistic infection at the time of admission\n* Concomitant use with: rifampin, carbamazepine, oxcarbazepine, phenytoin and phenobarbital or any contraindication to one of the drugs of the study\n* Known hepatitis B co-infection\n* Pregnancy (There is insufficient data for people who become pregnant on CAB or those planning to conceive because available pregnancy PK data are limited (n = 3), and data on clinical outcomes in pregnancy are extremely limited. Therefore, CAB is Not Recommended for pregnant or nonpregnant people initiating or restarting ART or for those whose current regimen is not well tolerated and\u002For not fully suppressive)",{"count":154,"type":20},50,"OBSERVATIONAL","This protocol will assess the level of satisfaction, acceptance of treatment and quality of life of patients with undetectable HIV who voluntarily change from oral to injectable antiretroviral treatment at 72 weeks of follow-up.",[158,159,160,28],"Patient Satisfaction","Patient Preference","Quality of Life",[162,163,164,165,166,167],"Quality of life","Acceptability","Satisfaction","Preference","HIV","Long acting- cabotegravir","NOT_YET_RECRUITING","2024-11-05",{"date":171,"type":44},"2024-11-07",{"date":173,"type":20},"2025-05-01",{"date":175,"type":20},"2026-05-01",{"name":177,"class":51},"Pontificia Universidad Catolica de Chile",{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":183,"acronym":4,"eligibilityCriteria":184,"healthyVolunteers":11,"sex":17,"minAge":60,"maxAge":185,"enrollmentInfo":186,"targetDuration":4,"studyType":21,"phases":187,"briefSummary":188,"conditions":189,"keywords":195,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":208,"startDateStruct":210,"completionDateStruct":212,"leadSponsor":214,"locationsCount":81},"100558335","body-oriented-psychotherapy-for-individuals-with-a-history-of-child-maltreatment-and-trauma-related-symptoms-100558335","NCT06549777","Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms","Body-oriented Psychotherapy vs. Psychoeducation and Treatment Information for Individuals With a History of Child Maltreatment and Trauma-related Symptoms: Assessing Safety, Feasibility, Acceptability, and Preliminary Outcomes","Inclusion Criteria:\n\n* Adults (18 years or older).\n* Proficiency in Swedish Language.\n* Access to a computer\u002Finternet.\n* Meeting CTQ-cutoff for CM history (CTQ rating higher than 'none \u002F minimal' in at least one of the subscales according to Bernstein and Fink (1998) (i.e. ≥10 for emotional neglect, ≥ 8 for physical neglect, ≥9 for emotional abuse, ≥8 for physical abuse and ≥6 for sexual abuse).\n* Meeting at least moderate\u002Fsevere PTSD or complex PTSD symptoms on the ITQ.\n* If taking medication, it must have been ongoing for at least 3 months and the dose must have been stable for 1 month.\n* Signed informed consent provided.\n\nExclusion Criteria:\n\n* Participants screen positive for alcohol (AUDIT) or substance abuse (DUDIT).\n* Psychotic symptoms, ongoing manic episode, acute suicidality.\n* If ongoing medication has an impact on the physiological data (ECG) recorded during the social paradigms, physiological data will be excluded from the analyses (but not exclusion for the treatment).\n* Have current (pre-assessment) ongoing psychological treatment focusing on social safeness, PTSD or complex PTSD.","100 Years",{"count":154,"type":20},[23],"This Pilot Randomized Controlled Trial (RCT) overall aim is to establish the safety, feasibility, acceptability and preliminary effects of a body-oriented psychotherapy, Somatic Experiencing (SE), on social functioning and mental health among adults with a history of Child Maltreatment (CM) and symptoms of posttraumatic stress disorder (PTSD) or complex posttraumatic stress disorder (CPTSD). Participants will be randomized either to an SE-group (n=25, psychoeducation, and information about treatment possibilities + 15-session SE treatment) or to a control group (n=25, same psychoeducation and information about treatment possibilities + regular phone calls to provide updates on their well-being and if they started a treatment). Given the lack of research on the effect of SE on Psychological Safety in this population, while SE has not yet been introduced into the Swedish health care system, special consideration will be given to participant safety, feasibility and acceptability of the SE-treatment. This includes monitoring (and assessing) for serious adverse events (SAEs) and adverse events (AEs), if conducting an RCT on SE in our target sample is feasible (e.g., achieving the target sample goal, assessing attrition rates and session attendance) and the acceptance of the used SE intervention (e.g., positive evaluations and willingness to recommend the treatment). Next to assessing safety, feasibility and acceptability, preliminary outcomes (self-report and experimental measures) will be evaluated at pre-treatment, post-treatment (20 weeks after pre), and at a 20-week follow-up, assessing primary outcomes (Psychological Safety) and secondary outcomes (Social Safeness, PTSD, CPTSD, Depression), as well as additional factors (e.g., interoception) that could contribute to decreased mental health and social functioning issues. Additionally, participants' behavioral (e.g., interpersonal distance) and physiological responses (HR, HRV, EDA) to social stimuli will be assessed pre- and post-treatment in an experimental setup to explore SE's potential to reduce Negative Affect and increase Positive Affect (Activated, Relaxed, Safe\u002FContent) in response to social stress.",[190,28,191,192,193,194],"Safety, Psychological","Psychological Safety","Maltreatment, Child","Post Traumatic Stress Disorder","Complex Post-Traumatic Stress Disorder",[196,197,198,199,200,201,202,203,204,205,206],"Safety","Feasibility","Body-oriented intervention","Somatic Experiencing","Psychological safety","Social safeness","Childhood maltreatment","Post traumatic stress disorder","Complex Post traumatic stress disorder","Interoception","Depression","2024-10-11",{"date":209,"type":44},"2024-10-15",{"date":211,"type":44},"2024-09-06",{"date":213,"type":20},"2026-11",{"name":215,"class":51},"Monique Pfaltz",{"id":217,"slug":218,"hasResults":11,"nctId":219,"briefTitle":220,"officialTitle":220,"acronym":221,"eligibilityCriteria":222,"healthyVolunteers":11,"sex":17,"minAge":60,"maxAge":4,"enrollmentInfo":223,"targetDuration":4,"studyType":21,"phases":225,"briefSummary":226,"conditions":227,"keywords":231,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":246},"100560318","digital-navigators-for-acceptance-and-competence-development-with-mental-health-apps-100560318","NCT06575582","Digital Navigators for Acceptance and Competence Development with Mental Health Apps","DigiNavi","Inclusion Criteria:\n\n* Main diagnosis according to ICD 10 F00-F69, F80-F99\n* Capacity to consent is given\n* Sufficient language skills for an interview in German\n* Participants have access to modern digital hardware (smartphone)\n* Basic knowledge of how to operate a smartphone\n\nExclusion Criteria:\n\n* Acute danger to self or others\n* Patients have received prompt (\\\u003C= 3 weeks) qualified psychiatric or psychotherapeutic treatment\n* Severe organic brain diseases with cognitive deficits\n* Intellectual disability",{"count":224,"type":20},116,[23],"The goal of this clinical trial is to learn if and how so called \"Digital Navigators\" (DN) can help general practitioners, outpatient psychiatrists and psychologists as well as their treated patients to use digital mental health apps (DiGAs) and integrate it into their treatment. The main questions it aims to answer are:\n\n* What are the chances and implementation barriers of DN?\n* What are the acceptance and expectations towards DN?\n* Do DN affect the psychological health of patients?\n* Do DN affect the digital health literacy and technical competence of participants?\n\nEmployees of medical teams (e.g. medical assistants) receive training to become a DN. Afterwards patients are accompanied and supported by the DN for 12 weeks to select and use a suitable app for their mental disorder.",[28,228,229,230],"Engagement, Patient","Nurse's Role","Mental Disorder",[232,233,234,235,236],"digital health","ehealth","mhealth","mental health","health literacy","2024-08-29",{"date":239,"type":44},"2024-09-03",{"date":241,"type":44},"2024-07-15",{"date":243,"type":20},"2025-07-14",{"name":245,"class":51},"Medizinische Hochschule Brandenburg Theodor Fontane",6]