[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acellular-dermal-matrix\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acellular-dermal-matrix":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100632327","assessment-of-two-soft-tissue-augmentation-using-acellular-dermis-around-dental-implants-100632327",false,"NCT07512245","Assessment of Two Soft Tissue Augmentation Using Acellular Dermis Around Dental Implants","Assessment of Two Soft Tissue Augmentation Protocols Using Acellular Dermis for Augmentation of Soft Tissue Quantity and Quality Around Dental Implants","Inclusion Criteria:\n\n* English speaking\n* At least 18 years old\n* Must be a patient of the UAB Dental School\n* Able to read and understand informed consent document\n* Patients presenting with a single edentulous site planned for dental implant placement deemed deficient in soft tissue peri-implant phenotype (\\> 2mm width of keratinized tissue, \\\u003C 1mm marginal soft tissue thickness, and\u002For \\> 2mm vertical soft tissue height)\n* Presence of periodontally healthy, non-carious neighboring teeth and\u002For healthy restored dental implants on either side of edentulous site planned for dental implant placement.\n* No anticipated need for surgical and\u002For endodontic care at teeth adjacent to the proposed surgical site during the study period.\n\nExclusion Criteria:\n\n* Non-English speaking\n* Less than 18 years old\n* Smokers\u002Ftobacco users (\\>10 cigarettes\u002Fday)\n* Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing\n* Edentulous sites treatment planned for dental implant placement with adequate implant site soft tissue quality\u002Fquantity (\\> 2mm width of keratinized tissue, \\> 1mm marginal soft tissue thickness, and\u002For \\> 2mm vertical soft tissue height).\n* Absence of adjacent teeth\u002Fimplants on either side of the tooth to be extracted and\u002For edentulous sites where 2 or more adjacent implants are planned.",true,"ALL","18 Years","85 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to compare soft tissue grafting with acellular dermis at Phase I or Phase II dental implant surgery.",[28,29],"Acellular Dermal Matrix","Alveolar Mucosa",[31],"soft tissue graft","NOT_YET_RECRUITING","2026-06-22",{"date":35,"type":36},"2026-06-25","ACTUAL",{"date":38,"type":22},"2026-08",{"date":40,"type":22},"2028-12",{"name":42,"class":43},"University of Alabama at Birmingham","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":44},"100638981","evaluating-the-barrier-function-regenerative-capacity-and-soft-tissue-outcomes-of-acellular-dermal-matrix-100638981","NCT07613047","Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix","A Prospective, Double-Arm, Randomized Controlled Trial Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix Compared to Resorbable Collagen Membranes in Edentulous Ridge Augmentation","Inclusion Criteria:\n\n* English speaking\n* At least 18 years old\n* Must be a patient of the UAB Dental School\n* Able to read and understand informed consent document\n* Patients presenting with a diagnosed need horizontal ridge augmentation with GBR without simultaneous implant placement, to allow for future dental implant placement.\n* Presence of periodontally healthy, non-carious neighboring teeth and\u002For healthy restored dental implants on either side of the edentulous span planned for GBR, or unhealthy adjacent teeth to be extracted during the same visit.\n* ≤4 mm ridge width in a Seibert Class I Edentulous span19\n* No anticipated need for surgical and\u002For endodontic care at planned teeth adjacent to the proposed surgical site during the study period.\n\nExclusion Criteria:\n\n* Non-English speaking\n* Less than 18 years old\n* Smokers\u002Fnicotine users (defined as currently reporting use of any form of tobacco\u002Fnicotine products)\n* Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing, including:\n\n  * Uncontrolled diabetes (HbA1c \\> 7%)\n  * Untreated periodontal disease\n  * History of head\u002Fneck radiation\n  * IV bisphosphonates\n  * Immunocompromised state\n  * Pregnancy\n  * Acute infection at site\n* Documented or suspected allergy or sensitivity to any study product",{"count":53,"type":22},70,[25],"This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.",[28,57,58],"Bone Grafting","Soft Tissue Grafting",[31],"2026-05-28",{"date":62,"type":36},"2026-06-01",{"date":64,"type":22},"2026-10",{"date":66,"type":22},"2028-10",{"name":42,"class":43}]