[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acl-repair\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acl-repair":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100562429","the-effect-of-pre-operative-cryoneurolysis-on-post-operative-narcotic-consumption-in-patients-undergoing-autograft-acl-reconstruction-100562429",false,"NCT06603051","The Effect of Pre-Operative Cryoneurolysis on Post-Operative Narcotic Consumption in Patients Undergoing Autograft ACL Reconstruction","Inclusion Criteria:\n\n* \\- Patients aged 14 and over\n* Patients who are patients within the PI's practice\n* Patients who can speak and read English\n* Patients undergoing autograft ACL reconstruction.\n* Patients who are opioid naïve\n\nExclusion Criteria:\n\n* \\- Under the age of 14\n* Non-English speaking\u002Freading patients\n* Patients with Reynauds' syndrome\n* Patients with skin disorders or hypo-vascularity\n* Patients undergoing allograft ACL reconstruction.\n* Patients who consistently use opioids preoperatively","ALL","14 Years",{"count":18,"type":19},20,"ESTIMATED","INTERVENTIONAL",[22],"NA","The purpose of the research is to investigate the effect of preoperative Cryoneurolysis of the knee on postoperative pain management in patients undergoing autograft anterior cruciate ligament (ACL) reconstruction (a surgical procedure that makes a new ACL using the patient's own tendon). Cryoneurolysis is an approved process of applying extreme cold temperatures to targeted nerves in order to decrease or eliminate pain. . If you take part in the research, you will be randomly assigned (assigned by chance, like a flip of a coin) to Group A (standard care) or Group B (standard care plus Cryoneurolysis). Participants in both groups will undergo standard ACL reconstruction and receive standard preoperative and postoperative pain management. Participants in Group B only will also receive a standard treatment of Cryoneurolysis to their surgical knee within 7-10 days before their scheduled surgery. Participants in both groups (A \\& B) will be asked to bring their remaining postoperative pain medication to their postoperative follow-up appointments for review by study personnel. Participants will also be asked to complete a survey about their knee activity, function and symptoms at these appointments. Your time in the study will last until the completion of the 12-week postoperative follow-up appointment.",[25],"ACL Repair",[25,27],"Cryoneurolysis","RECRUITING","2026-05-11",{"date":31,"type":32},"2026-05-12","ACTUAL",{"date":34,"type":32},"2024-08-28",{"date":36,"type":19},"2027-10",{"name":38,"class":39},"Virtua Health, Inc.","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":15,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":20,"phases":52,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100622527","isokinetic-exercise-combined-with-blood-flow-restriction-high-load-vs-low-load-training-100622527","NCT07384780","Isokinetic Exercise Combined With Blood Flow Restriction: High-Load Vs Low-Load Training","Isokinetic Exercise Combined With Blood Flow Restriction: High-Load Vs Low-Load Training : A Randomized Controlled Trial in Post-ACL Reconstruction Populations","Inclusion Criteria:\n\nFor ACLR group:\n\n•Isolated unilateral ACL reconstruction 8-16 weeks post-surgery with medical clearance for moderate to high resistance training.\n\nFor control group(healthy population):\n\n* Healthy adults with no musculoskeletal pathology.\n\nExclusion Criteria:\n\n* History of cardiovascular or metabolic diseases\n* Deep vein thrombosis\n* Coagulopathy\n* Hypertension\n* Skin lesions or infections at the site of BFR cuff administration\n* Neuromuscular disorders\n* Non-clearance from the surgeon or physiotherapist or resistance training.",true,"18 Years","35 Years",{"count":51,"type":19},60,[22],"The goal of this clinical trial is to see which type of strengthening exercise with a tight band (blood flow restriction) helps people recover better after ACL reconstruction. The study includes adults after ACL surgery who are doing physiotherapy to rebuild thigh muscle strength and knee function.\n\nThe main questions are:\n\n* Does heavy strengthening with blood flow restriction improve thigh strength, knee function, and daily activities more than light strengthening with blood flow restriction after ACL surgery?\n* Can light strengthening with blood flow restriction give similar benefits to heavy strengthening while putting less strain on the knee?\n\nResearchers will compare a heavy-exercise program plus blood flow restriction to a light-exercise program plus blood flow restriction to see which gives better strength and functional improvements.\n\nParticipants will:\n\n* Come for supervised physiotherapy sessions and do knee exercises on a machine, using either heavy or light loads while a cuff on the thigh gently squeezes to reduce blood flow.\n* Have their leg strength, and knee questionnaires checked several times during the study.",[55,25],"ACL Reconstruction",[57,58,59,60,55,61,62,63,64,65,66,67,68,69,70],"blood flow restriction training ACL","Blood flow restriction","ACL Rehab","ACLR","BFR therapy anterior cruciate ligament reconstruction","BFR therapy ACLR","BFR Therapy","low-load versus high-load BFR knee rehabilitation","isokinetic strength training after ACL surgery","physiotherapy rehabilitation protocol ACL isokinetic BFR","Knee physiotherapy","ACL","ACL Isokinetic","ACLٍ Isokinetic","NOT_YET_RECRUITING","2026-02-03",{"date":74,"type":32},"2026-02-05",{"date":76,"type":19},"2026-02",{"date":78,"type":19},"2026-06",{"name":80,"class":39},"Gulf Medical University"]